-
1
-
-
11844291300
-
Protein aggregation and its inhibition in biopharmaceutics
-
Wang W. 2005. Protein aggregation and its inhibition in biopharmaceutics. Int J Pharm 289 (1-2): 1-30.
-
(2005)
Int J Pharm.
, vol.289
, Issue.1-2
, pp. 1-30
-
-
Wang, W.1
-
2
-
-
0025149544
-
The effects of formulation additives on the degradation of freeze-dried ribonuclease A
-
Townsend MW, Byron PR, DeLuca PP. 1990. The effects of formulation additives on the degradation of freeze-dried ribonuclease A. Pharm Res 7 (10): 1086-1091.
-
(1990)
Pharm Res.
, vol.7
, Issue.10
, pp. 1086-1091
-
-
Townsend, M.W.1
Byron, P.R.2
DeLuca, P.P.3
-
3
-
-
0025671869
-
Refolding and aggregation of bovine carbonic anhydrase B: Quasi-elastic light scattering analysis
-
Cleland JL, Wang DI. 1990. Refolding and aggregation of bovine carbonic anhydrase B: Quasi-elastic light scattering analysis. Biochemistry 29 (50): 11072-11078.
-
(1990)
Biochemistry.
, vol.29
, Issue.50
, pp. 11072-11078
-
-
Cleland, J.L.1
Wang, D.I.2
-
4
-
-
14444271579
-
Structural and functional differences between glycosylated and non-glycosylated forms of human interferon-beta (IFN-beta)
-
Runkel L, Meier W, Pepinsky RB, Karpusas M, Whitty A, Kimball K, Brickelmaier M, Muldowney C, Jones W, Goelz SE. 1998. Structural and functional differences between glycosylated and non-glycosylated forms of human interferon-beta (IFN-beta). Pharm Res 15 (4): 641-649.
-
(1998)
Pharm Res.
, vol.15
, Issue.4
, pp. 641-649
-
-
Runkel, L.1
Meier, W.2
Pepinsky, R.B.3
Karpusas, M.4
Whitty, A.5
Kimball, K.6
Brickelmaier, M.7
Muldowney, C.8
Jones, W.9
Goelz, S.E.10
-
5
-
-
0034688449
-
Supercritical fluid precipitation of recombinant human immunoglobulin from aqueous solutions
-
Nesta DP, Elliott JS, Warr JP. 2000. Supercritical fluid precipitation of recombinant human immunoglobulin from aqueous solutions. Biotechnol Bioeng 67 (4): 457-464.
-
(2000)
Biotechnol Bioeng.
, vol.67
, Issue.4
, pp. 457-464
-
-
Nesta, D.P.1
Elliott, J.S.2
Warr, J.P.3
-
6
-
-
0037392796
-
Correlation of rFVIII inactivation with aggregation in solution
-
Wang W, Kelner DN. 2003. Correlation of rFVIII inactivation with aggregation in solution. Pharm Res 20 (4): 693-700.
-
(2003)
Pharm Res.
, vol.20
, Issue.4
, pp. 693-700
-
-
Wang, W.1
Kelner, D.N.2
-
7
-
-
36749035336
-
Protein folding: Are we there yet?
-
Clark AC. 2008. Protein folding: Are we there yet? Arch Biochem Biophys 469 (1): 1-3.
-
(2008)
Arch Biochem Biophys.
, vol.469
, Issue.1
, pp. 1-3
-
-
Clark, A.C.1
-
8
-
-
62749099087
-
Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality
-
Carpenter JF, Randolph TW, Jiskoot W, Crommelin DJ, Middaugh CR, Winter G, Fan YX, Kirshner S, Verthelyi D, Kozlowski S, Clouse KA, Swann PG, Rosenberg A, Cherney B. 2008. Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality. J Pharm Sci. doi: 10.1002/jps.21530.
-
(2008)
J Pharm Sci
-
-
Carpenter, J.F.1
Randolph, T.W.2
Jiskoot, W.3
Crommelin, D.J.4
Middaugh, C.R.5
Winter, G.6
Fan, Y.X.7
Kirshner, S.8
Verthelyi, D.9
Kozlowski, S.10
Clouse, K.A.11
Swann, P.G.12
Rosenberg, A.13
Cherney, B.14
-
9
-
-
0031932169
-
Protein aggregation: Folding aggregates, inclusion bodies and amyloid
-
Fink AL. 1998. Protein aggregation: Folding aggregates, inclusion bodies and amyloid. Fold Des 3 (1): R9-R23.
-
(1998)
Fold Des.
, vol.3
, Issue.1
-
-
Fink, A.L.1
-
10
-
-
0000594410
-
Theory for the aggregation of proteins and copolymers
-
Fields G, Alonso D, Stiger D, Dill KA. 1992. Theory for the aggregation of proteins and copolymers. J Phys Chem 96: 3974-3981.
-
(1992)
J Phys Chem.
, vol.96
, pp. 3974-3981
-
-
Fields, G.1
Alonso, D.2
Stiger, D.3
Dill, K.A.4
-
11
-
-
0026649261
-
Molecular basis of co-operativity in protein folding
-
III. Structural identification of folding units and folding intermediates
-
Murphy KP, Bhakuni V, Xie D, Freire E. 1992. Molecular basis of co-operativity in protein folding. III. Structural identification of folding units and folding intermediates. J Mol Biol 227 (1): 293-306.
-
(1992)
J Mol Biol.
, vol.227
, Issue.1
, pp. 293-306
-
-
Murphy, K.P.1
Bhakuni, V.2
Xie, D.3
Freire, E.4
-
12
-
-
0032564420
-
A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma
-
Kendrick BS, Carpenter JF, Cleland JL, Randolph TW. 1998. A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma. Proc Natl Acad Sci U S A 95 (24): 14142-14146.
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, Issue.24
, pp. 14142-14146
-
-
Kendrick, B.S.1
Carpenter, J.F.2
Cleland, J.L.3
Randolph, T.W.4
-
13
-
-
0023934323
-
Kinetics of adsorption of proteins at interfaces: Role of protein conformation in diffusional adsorption
-
Damodaran S, Song KB. 1988. Kinetics of adsorption of proteins at interfaces: Role of protein conformation in diffusional adsorption. Biochim Biophys Acta 954 (3): 253-264.
-
(1988)
Biochim Biophys Acta.
, vol.954
, Issue.3
, pp. 253-264
-
-
Damodaran, S.1
Song, K.B.2
-
14
-
-
0032932954
-
Association of partially-folded intermediates of staphylococcal nuclease induces structure and stability
-
Uversky VN, Karnoup AS, Khurana R, Segel DJ, Doniach S, Fink AL. 1999. Association of partially-folded intermediates of staphylococcal nuclease induces structure and stability. Protein Sci 8 (1): 161-173.
-
(1999)
Protein Sci.
, vol.8
, Issue.1
, pp. 161-173
-
-
Uversky, V.N.1
Karnoup, A.S.2
Khurana, R.3
Segel, D.J.4
Doniach, S.5
Fink, A.L.6
-
15
-
-
42649110014
-
The in vivo and in vitro aggregation properties of globular proteins correlate with their conformational stability: The SH3 case
-
Espargaro A, Castillo V, de Groot NS, Ventura S. 2008. The in vivo and in vitro aggregation properties of globular proteins correlate with their conformational stability: The SH3 case. J Mol Biol 378(5): 1116-1131.
-
(2008)
J Mol Biol.
, vol.378
, Issue.5
, pp. 1116-1131
-
-
Espargaro, A.1
Castillo, V.2
De Groot, N.S.3
Ventura, S.4
-
16
-
-
38749131194
-
How native proteins aggregate in solution: A dynamic Monte Carlo simulation
-
Zhang L, Lu D, Liu Z. 2008. How native proteins aggregate in solution: A dynamic Monte Carlo simulation. Biophys Chem 133 (1-3): 71-80.
-
(2008)
Biophys Chem.
, vol.133
, Issue.1-3
, pp. 71-80
-
-
Zhang, L.1
Lu, D.2
Liu, Z.3
-
17
-
-
67449132077
-
Principles, approaches, and challenges for predicting protein aggregation rates and shelf life
-
Weiss WFt, Young TM, Roberts CJ. 2008. Principles, approaches, and challenges for predicting protein aggregation rates and shelf life. J Pharm Sci. doi: 10.1002/ jps.21521.
-
(2008)
J Pharm Sci
-
-
Weiss, W.Ft.1
Young, T.M.2
Roberts, C.J.3
-
18
-
-
24344497281
-
Aggregation of granulocyte-colony stimulating factor in vitro involves a conformationally altered monomeric state
-
Raso SW, Abel J, Barnes JM, Maloney KM, Pipes G, Treuheit MJ, King J, Brems DN. 2005. Aggregation of granulocyte-colony stimulating factor in vitro involves a conformationally altered monomeric state. Protein Sci 14 (9): 2246-2257.
-
(2005)
Protein Sci.
, vol.14
, Issue.9
, pp. 2246-2257
-
-
Raso, S.W.1
Abel, J.2
Barnes, J.M.3
Maloney, K.M.4
Pipes, G.5
Treuheit, M.J.6
King, J.7
Brems, D.N.8
-
19
-
-
0028120343
-
Scrapie amyloid (prion) protien has the conformational characteristics of an aggregated molten globule folding intermediate
-
Safar J, Roller PP, Gajdusek DC, Gibbs JCJ. 1994. Scrapie amyloid (prion) protien has the conformational characteristics of an aggregated molten globule folding intermediate. Biochemistry 33: 8375-8383.
-
(1994)
Biochemistry.
, vol.33
, pp. 8375-8383
-
-
Safar, J.1
Roller, P.P.2
Gajdusek, D.C.3
Gibbs, J.C.J.4
-
20
-
-
0026833079
-
Transient association of the first intermediate during the refolding of bovine carbonic anhydrase B
-
Cleland JL, Wang DI. 1992. Transient association of the first intermediate during the refolding of bovine carbonic anhydrase B. Biotechnol Prog 8 (2): 97-103.
-
(1992)
Biotechnol Prog.
, vol.8
, Issue.2
, pp. 97-103
-
-
Cleland, J.L.1
Wang, D.I.2
-
21
-
-
0032731353
-
Structural mapping of an aggregation nucleation site in a molten globule intermediate
-
Hammarstrom P, Persson M, Freskgard PO, Martensson LG, Andersson D, Jonsson BH, Carlsson U. 1999. Structural mapping of an aggregation nucleation site in a molten globule intermediate. J Biol Chem 274 (46): 32897-32903.
-
(1999)
J Biol Chem.
, vol.274
, Issue.46
, pp. 32897-32903
-
-
Hammarstrom, P.1
Persson, M.2
Freskgard, P.O.3
Martensson, L.G.4
Andersson, D.5
Jonsson, B.H.6
Carlsson, U.7
-
22
-
-
0030292616
-
Molten globule intermediate of recombinant human growth hormone: Stabilization with surfactants
-
Bam NB, Cleland JL, Randolph TW. 1996. Molten globule intermediate of recombinant human growth hormone: Stabilization with surfactants. Biotechnol Prog 12 (6): 801-809.
-
(1996)
Biotechnol Prog.
, vol.12
, Issue.6
, pp. 801-809
-
-
Bam, N.B.1
Cleland, J.L.2
Randolph, T.W.3
-
23
-
-
0030959947
-
Toward understanding insulin fibrillation
-
Brange J, Andersen L, Laursen ED, Meyn G, Rasmussen E. 1997. Toward understanding insulin fibrillation. J Pharm Sci 86 (5): 517-525.
-
(1997)
J Pharm Sci.
, vol.86
, Issue.5
, pp. 517-525
-
-
Brange, J.1
Andersen, L.2
Laursen, E.D.3
Meyn, G.4
Rasmussen, E.5
-
24
-
-
0031056829
-
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
-
Booth DR, Sunde M, Bellotti V, Robinson CV, Hutchinson WL, Fraser PE, Hawkins PN, Dobson CM, Radford SE, Blake CC, Pepys MB. 1997. Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis. Nature 385 (6619): 787-793.
-
(1997)
Nature.
, vol.385
, Issue.6619
, pp. 787-793
-
-
Booth, D.R.1
Sunde, M.2
Bellotti, V.3
Robinson, C.V.4
Hutchinson, W.L.5
Fraser, P.E.6
Hawkins, P.N.7
Dobson, C.M.8
Radford, S.E.9
Blake, C.C.10
Pepys, M.B.11
-
25
-
-
0343416947
-
Polymerization mechanism of polypeptide chain aggregation
-
Speed MA, King J, Wang DIC. 1997. Polymerization mechanism of polypeptide chain aggregation. Biotechnol Bioeng 54: 333-343.
-
(1997)
Biotechnol Bioeng.
, vol.54
, pp. 333-343
-
-
Speed, M.A.1
King, J.2
Wang, D.I.C.3
-
26
-
-
0033603336
-
Formation of fibrous aggregates from a non-native intermediate: The isolated P22 tailspike beta-helix domain
-
Schuler B, Rachel R, Seckler R. 1999. Formation of fibrous aggregates from a non-native intermediate: The isolated P22 tailspike beta-helix domain. J Biol Chem 274 (26): 18589-18596.
-
(1999)
J Biol Chem.
, vol.274
, Issue.26
, pp. 18589-18596
-
-
Schuler, B.1
Rachel, R.2
Seckler, R.3
-
27
-
-
0033537635
-
Aggregation and assembly of phage P22 temperature-sensitive coat protein mutants in vitro mimic the in vivo phenotype
-
Teschke CM. 1999. Aggregation and assembly of phage P22 temperature-sensitive coat protein mutants in vitro mimic the in vivo phenotype. Biochemistry 38 (10): 2873-2881.
-
(1999)
Biochemistry.
, vol.38
, Issue.10
, pp. 2873-2881
-
-
Teschke, C.M.1
-
28
-
-
0242515822
-
Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor
-
Chi EY, Krishnan S, Kendrick BS, Chang BS, Carpenter JF, Randolph TW. 2003. Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor. Protein Sci 12 (5): 903-913.
-
(2003)
Protein Sci.
, vol.12
, Issue.5
, pp. 903-913
-
-
Chi, E.Y.1
Krishnan, S.2
Kendrick, B.S.3
Chang, B.S.4
Carpenter, J.F.5
Randolph, T.W.6
-
29
-
-
1242271236
-
Aggregation kinetics of bovine serum albumin studied by FTIR spectroscopy and light scattering
-
Militello V, Casarino C, Emanuele A, Giostra A, Pullara F, Leone M. 2004. Aggregation kinetics of bovine serum albumin studied by FTIR spectroscopy and light scattering. Biophys Chem 107 (2): 175-187.
-
(2004)
Biophys Chem.
, vol.107
, Issue.2
, pp. 175-187
-
-
Militello, V.1
Casarino, C.2
Emanuele, A.3
Giostra, A.4
Pullara, F.5
Leone, M.6
-
30
-
-
11144317965
-
Thermal induced conformational changes involved in the aggregation pathways of beta-lactoglobulin
-
Vetri V, Militello V. 2005. Thermal induced conformational changes involved in the aggregation pathways of beta-lactoglobulin. Biophys Chem 113 (1): 83-91.
-
(2005)
Biophys Chem.
, vol.113
, Issue.1
, pp. 83-91
-
-
Vetri, V.1
Militello, V.2
-
31
-
-
33745020119
-
Effect of buffer species on the thermally induced aggregation of interferon-tau
-
Katayama DS, Nayar R, Chou DK, Valente JJ, Cooper J, Henry CS, Vander Velde DG, Villarete L, Liu CP, Manning MC. 2006. Effect of buffer species on the thermally induced aggregation of interferon-tau. J Pharm Sci 95 (6): 1212-1226.
-
(2006)
J Pharm Sci.
, vol.95
, Issue.6
, pp. 1212-1226
-
-
Katayama, D.S.1
Nayar, R.2
Chou, D.K.3
Valente, J.J.4
Cooper, J.5
Henry, C.S.6
Vander Velde, D.G.7
Villarete, L.8
Liu, C.P.9
Manning, M.C.10
-
32
-
-
38949124389
-
The effect of small molecules in modulating the chaperone activity of alpha B-crystallin against ordered and disordered protein aggregation
-
Ecroyd H, Carver JA. 2008. The effect of small molecules in modulating the chaperone activity of alpha B-crystallin against ordered and disordered protein aggregation. FEBS J 275 (5): 935-947.
-
(2008)
FEBS J.
, vol.275
, Issue.5
, pp. 935-947
-
-
Ecroyd, H.1
Carver, J.A.2
-
33
-
-
34249860495
-
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct
-
Necula M, Kayed R, Milton S, Glabe CG. 2007. Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. J Biol Chem 282 (14): 10311-10324.
-
(2007)
J Biol Chem.
, vol.282
, Issue.14
, pp. 10311-10324
-
-
Necula, M.1
Kayed, R.2
Milton, S.3
Glabe, C.G.4
-
34
-
-
27644477360
-
Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution
-
Liu J, Nguyen MD, Andya JD, Shire SJ. 2005. Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution. J Pharm Sci 94 (9): 1928-1940.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.9
, pp. 1928-1940
-
-
Liu, J.1
Nguyen, M.D.2
Andya, J.D.3
Shire, S.J.4
-
35
-
-
52449112053
-
High concentration formulations of recombinant human interleukin-1 receptor antagonist: II
-
Aggregation kinetics
-
Alford JR, Kendrick BS, Carpenter JF, Randolph TW. 2008. High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics. J Pharm Sci 97 (8): 3005-3021.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.8
, pp. 3005-3021
-
-
Alford, J.R.1
Kendrick, B.S.2
Carpenter, J.F.3
Randolph, T.W.4
-
36
-
-
55749113694
-
Reversible self-association of a concentrated monoclonal antibody solution mediated by Fab-Fab interaction that impacts solution viscosity
-
Kanai S, Liu J, Patapoff TW, Shire SJ. 2008. Reversible self-association of a concentrated monoclonal antibody solution mediated by Fab-Fab interaction that impacts solution viscosity. J Pharm Sci. doi:10.1002/jps.21322.
-
(2008)
J Pharm Sci
-
-
Kanai, S.1
Liu, J.2
Patapoff, T.W.3
Shire, S.J.4
-
37
-
-
44449108578
-
Nature and consequences of protein-protein interactions in high protein concentration solutions
-
Saluja A, Kalonia DS. 2008. Nature and consequences of protein-protein interactions in high protein concentration solutions. Int J Pharm 358 (1-2): 1-15.
-
(2008)
Int J Pharm.
, vol.358
, Issue.1-2
, pp. 1-15
-
-
Saluja, A.1
Kalonia, D.S.2
-
38
-
-
0141567459
-
Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation
-
Chi EY, Krishnan S, Randolph TW, Carpenter JF. 2003. Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation. Pharm Res 20 (9): 1325-1336.
-
(2003)
Pharm Res.
, vol.20
, Issue.9
, pp. 1325-1336
-
-
Chi, E.Y.1
Krishnan, S.2
Randolph, T.W.3
Carpenter, J.F.4
-
39
-
-
0031751766
-
Self-association properties of monomeric insulin analogs under formulation conditions
-
Richards JP, Stickelmeyer MP, Flora DB, Chance RE, Frank BH, DeFelippis MR. 1998. Self-association properties of monomeric insulin analogs under formulation conditions. Pharm Res 15 (9): 1434-1441.
-
(1998)
Pharm Res.
, vol.15
, Issue.9
, pp. 1434-1441
-
-
Richards, J.P.1
Stickelmeyer, M.P.2
Flora, D.B.3
Chance, R.E.4
Frank, B.H.5
DeFelippis, M.R.6
-
40
-
-
33745413982
-
Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution
-
Bajaj H, Sharma VK, Badkar A, Zeng D, Nema S, Kalonia DS. 2006. Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution. Pharm Res 23 (6): 1382-1394.
-
(2006)
Pharm Res.
, vol.23
, Issue.6
, pp. 1382-1394
-
-
Bajaj, H.1
Sharma, V.K.2
Badkar, A.3
Zeng, D.4
Nema, S.5
Kalonia, D.S.6
-
41
-
-
34249898873
-
Effect of protein charge on the generation of aggregation-prone conformers
-
Broersen K, Weijers M, de Groot J, Hamer RJ, de Jongh HHJ. 2007. Effect of protein charge on the generation of aggregation-prone conformers. Biomacromolecules 8 (5): 1648-1656.
-
(2007)
Biomacromolecules.
, vol.8
, Issue.5
, pp. 1648-1656
-
-
Broersen, K.1
Weijers, M.2
De Groot, J.3
Hamer, R.J.4
De Jongh, H.H.J.5
-
42
-
-
33846839238
-
Protein particulates: Another generic form of protein aggregation?
-
Krebs MR, Devlin GL, Donald AM. 2007. Protein particulates: Another generic form of protein aggregation? Biophys J 92 (4): 1336-1342.
-
(2007)
Biophys J.
, vol.92
, Issue.4
, pp. 1336-1342
-
-
Krebs, M.R.1
Devlin, G.L.2
Donald, A.M.3
-
43
-
-
0030338340
-
Characterization, stability, and formulations of basic fibroblast growth factor
-
Wang YJ, Shahrokh Z, Vemuri S, Eberlein G, Beylin I, Busch M. 1996. Characterization, stability, and formulations of basic fibroblast growth factor. Pharm Biotechnol 9: 141-180.
-
(1996)
Pharm Biotechnol.
, vol.9
, pp. 141-180
-
-
Wang, Y.J.1
Shahrokh, Z.2
Vemuri, S.3
Eberlein, G.4
Beylin, I.5
Busch, M.6
-
44
-
-
0028234747
-
Major degradation products of basic fibroblast growth factor: Detection of succinimide and iso-aspartate in place of aspartate
-
Shahrokh Z, Eberlein G, Buckley D, Paranandi MV, Aswad DW, Stratton P, Mischak R, Wang YJ. 1994. Major degradation products of basic fibroblast growth factor: Detection of succinimide and iso-aspartate in place of aspartate. Pharm Res 11 (7): 936-944.
-
(1994)
Pharm Res.
, vol.11
, Issue.7
, pp. 936-944
-
-
Shahrokh, Z.1
Eberlein, G.2
Buckley, D.3
Paranandi, M.V.4
Aswad, D.W.5
Stratton, P.6
Mischak, R.7
Wang, Y.J.8
-
45
-
-
0027164092
-
Aggregates formed during storage of beta-galactosidase in solution and in the freeze-dried state
-
Yoshioka S, Aso Y, Izutsu K, Terao T. 1993. Aggregates formed during storage of beta-galactosidase in solution and in the freeze-dried state. Pharm Res 10 (5): 687-691.
-
(1993)
Pharm Res.
, vol.10
, Issue.5
, pp. 687-691
-
-
Yoshioka, S.1
Aso, Y.2
Izutsu, K.3
Terao, T.4
-
46
-
-
0028345740
-
The aggregation of bovine serum albumin in solution and in the solid state
-
Jordan GM, Yoshioka S, Terao T. 1994. The aggregation of bovine serum albumin in solution and in the solid state. J Pharm Pharmacol 46 (3): 182-185.
-
(1994)
J Pharm Pharmacol.
, vol.463
, pp. 182-185
-
-
Jordan, G.M.1
Yoshioka, S.2
Terao, T.3
-
47
-
-
4143094993
-
Specificity of disulfide bond formation during thermal aggregation in solutions of beta-lactoglobulin b and kappa-casein A
-
Livney YD, Dalgleish DG. 2004. Specificity of disulfide bond formation during thermal aggregation in solutions of beta-lactoglobulin b and kappa-casein A. J Agric Food Chem 52 (17): 5527-5532.
-
(2004)
J Agric Food Chem.
, vol.52
, Issue.17
, pp. 5527-5532
-
-
Livney, Y.D.1
Dalgleish, D.G.2
-
48
-
-
0346336103
-
Steric effects governing disulfide bond interchange during thermal aggregation in solutions of beta-lactoglobulin B and alpha-lactalbumin
-
Livney YD, Verespej E, Dalgleish DG. 2003. Steric effects governing disulfide bond interchange during thermal aggregation in solutions of beta-lactoglobulin B and alpha-lactalbumin. J Agric Food Chem 51 (27): 8098-8106.
-
(2003)
J Agric Food Chem.
, vol.51
, Issue.27
, pp. 8098-8106
-
-
Livney, Y.D.1
Verespej, E.2
Dalgleish, D.G.3
-
49
-
-
52449135457
-
The effect of sulfhydryl groups and disulphide linkage in the thermal aggregation of Z19 alpha-zein
-
Cabra V, Vazquez-Contreras E, Moreno A, Arreguin-Espinosa R. 2008. The effect of sulfhydryl groups and disulphide linkage in the thermal aggregation of Z19 alpha-zein. Biochim Biophys Acta 1784 (7-8): 1028-1036.
-
(2008)
Biochim Biophys Acta.
, vol.1784
, Issue.7-8
, pp. 1028-1036
-
-
Cabra, V.1
Vazquez-Contreras, E.2
Moreno, A.3
Arreguin-Espinosa, R.4
-
50
-
-
0027955039
-
Moisture-induced aggregation of lyophilized insulin
-
Costantino HR, Langer R, Klibanov AM. 1994. Moisture-induced aggregation of lyophilized insulin. Pharm Res 11 (1): 21-29.
-
(1994)
Pharm Res.
, vol.11
, Issue.1
, pp. 21-29
-
-
Costantino, H.R.1
Langer, R.2
Klibanov, A.M.3
-
51
-
-
0346100519
-
Dityrosine as a product of oxidative stress and fluorescent probe
-
Malencik DA, Anderson SR. 2003. Dityrosine as a product of oxidative stress and fluorescent probe. Amino Acids 25 (3-4): 233-247.
-
(2003)
Amino Acids.
, vol.25
, Issue.3-4
, pp. 233-247
-
-
Malencik, D.A.1
Anderson, S.R.2
-
52
-
-
0028789630
-
Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation
-
Schwendeman SP, Costantino HR, Gupta RK, Siber GR, Klibanov AM, Langer R. 1995. Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation. Proc Natl Acad Sci U S A 92 (24): 11234-11238.
-
(1995)
Proc Natl Acad Sci U S A.
, vol.92
, Issue.24
, pp. 11234-11238
-
-
Schwendeman, S.P.1
Costantino, H.R.2
Gupta, R.K.3
Siber, G.R.4
Klibanov, A.M.5
Langer, R.6
-
53
-
-
0346100519
-
Dityrosine as a product of oxidative stress and fluorescent probe
-
Malencik DA, Anderson SR. 2003. Dityrosine as a product of oxidative stress and fluorescent probe. Amino Acids 25 (3-4): 233-247.
-
(2003)
Amino Acids.
, vol.25
, Issue.3-4
, pp. 233-247
-
-
Malencik, D.A.1
Anderson, S.R.2
-
54
-
-
0034674038
-
Evidence for the involvement of histidine A(12) in the aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation
-
Khossravi M, Shire SJ, Borchardt RT. 2000. Evidence for the involvement of histidine A(12) in the aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation. Biochemistry 39 (19): 5876-5885.
-
(2000)
Biochemistry.
, vol.39
, Issue.19
, pp. 5876-5885
-
-
Khossravi, M.1
Shire, S.J.2
Borchardt, R.T.3
-
55
-
-
0025239329
-
In vitro non-enzymatic glycation and formation of browning products in the bovine lens alpha-crystallin
-
Liang JN, Rossi MT. 1990. In vitro non-enzymatic glycation and formation of browning products in the bovine lens alpha-crystallin. Exp Eye Res 50 (4): 367-371.
-
(1990)
Exp Eye Res.
, vol.50
, Issue.4
, pp. 367-371
-
-
Liang, J.N.1
Rossi, M.T.2
-
56
-
-
0033624640
-
Advanced glycation end products in human senile and diabetic cataractous lenses
-
Zarina S, Zhao HR, Abraham EC. 2000. Advanced glycation end products in human senile and diabetic cataractous lenses. Mol Cell Biochem 210 (1-2): 29-34.
-
(2000)
Mol Cell Biochem.
, vol.210
, Issue.1-2
, pp. 29-34
-
-
Zarina, S.1
Zhao, H.R.2
Abraham, E.C.3
-
57
-
-
49849100536
-
Effect of methionine oxidation on the structural properties, conformational stability, and aggregation of immunoglobulin light chain LEN
-
Hu D, Qin Z, Xue B, Fink AL, Uversky VN. 2008. Effect of methionine oxidation on the structural properties, conformational stability, and aggregation of immunoglobulin light chain LEN. Biochemistry (Mosc) 47 (33): 8665-8677.
-
(2008)
Biochemistry (Mosc).
, vol.47
, Issue.33
, pp. 8665-8677
-
-
Hu, D.1
Qin, Z.2
Xue, B.3
Fink, A.L.4
Uversky, V.N.5
-
58
-
-
0029028559
-
Aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation
-
Li S, Nguyen TH, Schoneich C, Borchardt RT. 1995. Aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation. Biochemistry 34 (17): 5762-5772.
-
(1995)
Biochemistry.
, vol.34
, Issue.17
, pp. 5762-5772
-
-
Li, S.1
Nguyen, T.H.2
Schoneich, C.3
Borchardt, R.T.4
-
59
-
-
32944455998
-
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
-
Hawkins CL, Davies MJ. 2005. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme. Chem Res Toxicol 18 (11): 1669-1677.
-
(2005)
Chem Res Toxicol.
, vol.18
, Issue.11
, pp. 1669-1677
-
-
Hawkins, C.L.1
Davies, M.J.2
-
60
-
-
0025890206
-
Stability of interleukin 1 beta (IL-1 beta) in aqueous solution: Analytical methods, kinetics, products, and solution formulation implications
-
Gu LC, Erdos EA, Chiang HS, Calderwood T, Tsai K, Visor GC, Duffy J, Hsu WC, Foster LC. 1991. Stability of interleukin 1 beta (IL-1 beta) in aqueous solution: Analytical methods, kinetics, products, and solution formulation implications. Pharm Res 8 (4): 485-490.
-
(1991)
Pharm Res.
, vol.8
, Issue.4
, pp. 485-490
-
-
Gu, L.C.1
Erdos, E.A.2
Chiang, H.S.3
Calderwood, T.4
Tsai, K.5
Visor, G.C.6
Duffy, J.7
Hsu, W.C.8
Foster, L.C.9
-
62
-
-
50049119429
-
Deamidation destabilizes and triggers aggregation of a lens protein
-
{beta}A3-crystallin
-
Takata T, Oxford JT, Demeler B, Lampi KJ. 2008. Deamidation destabilizes and triggers aggregation of a lens protein, {beta}A3-crystallin. Protein Sci. doi:10.1110/ ps.035410.108.
-
(2008)
Protein Sci
-
-
Takata, T.1
Oxford, J.T.2
Demeler, B.3
Lampi, K.J.4
-
63
-
-
33750078696
-
Glutamine deamidation destabilizes human gammaD-crystallin and lowers the kinetic barrier to unfolding
-
Flaugh SL, Mills IA, King J. 2006. Glutamine deamidation destabilizes human gammaD-crystallin and lowers the kinetic barrier to unfolding. J Biol Chem 281 (41): 30782-30793.
-
(2006)
J Biol Chem.
, vol.281
, Issue.41
, pp. 30782-30793
-
-
Flaugh, S.L.1
Mills, I.A.2
King, J.3
-
64
-
-
0035930625
-
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
-
von Bergen M, Barghorn S, Li L, Marx A, Biernat J, Mandelkow EM, Mandelkow E. 2001. Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure. J Biol Chem 276 (51): 48165-48174.
-
(2001)
J Biol Chem.
, vol.276
, Issue.51
, pp. 48165-48174
-
-
von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
Mandelkow, E.7
-
65
-
-
2942620074
-
Hsp70 reduces alpha-synuclein aggregation and toxicity
-
Klucken J, Shin Y, Masliah E, Hyman BT, McLean PJ. 2004. Hsp70 reduces alpha-synuclein aggregation and toxicity. J Biol Chem 279 (24): 25497-25502.
-
(2004)
J Biol Chem.
, vol.279
, Issue.24
, pp. 25497-25502
-
-
Klucken, J.1
Shin, Y.2
Masliah, E.3
Hyman, B.T.4
McLean, P.J.5
-
66
-
-
44949185533
-
Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids
-
Mizuguchi M, Hayashi A, Takeuchi M, Dobashi M, Mori Y, Shinoda H, Aizawa T, Demura M, Kawano K. 2008. Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids. Proteins 72 (1): 261-269.
-
(2008)
Proteins.
, vol.72
, Issue.1
, pp. 261-269
-
-
Mizuguchi, M.1
Hayashi, A.2
Takeuchi, M.3
Dobashi, M.4
Mori, Y.5
Shinoda, H.6
Aizawa, T.7
Demura, M.8
Kawano, K.9
-
67
-
-
33645911471
-
Interrelationships of glycosylation and aggregation kinetics for Peniophora lycii phytase
-
Hoiberg-Nielsen R, Fuglsang CC, Arleth L, Westh P. 2006. Interrelationships of glycosylation and aggregation kinetics for Peniophora lycii phytase. Biochemistry (Mosc) 45 (15): 5057-5066.
-
(2006)
Biochemistry (Mosc).
, vol.45
, Issue.15
, pp. 5057-5066
-
-
Hoiberg-Nielsen, R.1
Fuglsang, C.C.2
Arleth, L.3
Westh, P.4
-
68
-
-
15444374846
-
Role of arginine in the stabilization of proteins against aggregation
-
Baynes BM, Wang DI, Trout BL. 2005. Role of arginine in the stabilization of proteins against aggregation. Biochemistry 44 (12): 4919-4925.
-
(2005)
Biochemistry.
, vol.44
, Issue.12
, pp. 4919-4925
-
-
Baynes, B.M.1
Wang, D.I.2
Trout, B.L.3
-
69
-
-
33645513980
-
Theoretical approaches to protein aggregation
-
Gsponer J, Vendruscolo M. 2006. Theoretical approaches to protein aggregation. Protein Pept Lett 13 (3): 287-293.
-
(2006)
Protein Pept Lett.
, vol.13
, Issue.3
, pp. 287-293
-
-
Gsponer, J.1
Vendruscolo, M.2
-
70
-
-
0027006436
-
Amyoid fibril formation requires a chemically discriminating nucleation event: Studies of an amyloidogenic sequence from the bacterial protein OsmB
-
Jarrett JT, Lansbury PT Jr. 1993. Amyoid fibril formation requires a chemically discriminating nucleation event: Studies of an amyloidogenic sequence from the bacterial protein OsmB. Biochemistry 31: 12345-12352.
-
(1993)
Biochemistry.
, vol.31
, pp. 12345-12352
-
-
Jarrett, J.T.1
Lansbury, P.T.Jr.2
-
71
-
-
0034711745
-
Aggregation events occur prior to stable intermediate formation during refolding of interleukin 1beta
-
Finke JM, Roy M, Zimm BH, Jennings PA. 2000. Aggregation events occur prior to stable intermediate formation during refolding of interleukin 1beta. Biochemistry 39 (3): 575-583.
-
(2000)
Biochemistry.
, vol.39
, Issue.3
, pp. 575-583
-
-
Finke, J.M.1
Roy, M.2
Zimm, B.H.3
Jennings, P.A.4
-
73
-
-
0033584815
-
An FT-IR study of the beta-amyloid conformation: standardization of aggregation grade
-
Szabo Z, Klement E, Jost K, Zarandi M, Soos K, Penke B. 1999. An FT-IR study of the beta-amyloid conformation: standardization of aggregation grade. Biochem Biophys Res Commun 265 (2): 297-300.
-
(1999)
Biochem Biophys Res Commun.
, vol.265
, Issue.2
, pp. 297-300
-
-
Szabo, Z.1
Klement, E.2
Jost, K.3
Zarandi, M.4
Soos, K.5
Penke, B.6
-
74
-
-
37349050368
-
Nonnative protein polymers: Structure, morphology, and relation to nucleation and growth
-
Weiss WFt, Hodgdon TK, Kaler EW, Lenhoff AM, Roberts CJ. 2007. Nonnative protein polymers: Structure, morphology, and relation to nucleation and growth. Biophys J 93 (12): 4392-4403.
-
(2007)
Biophys J.
, vol.93
, Issue.12
, pp. 4392-4403
-
-
Weiss, W.Ft.1
Hodgdon, T.K.2
Kaler, E.W.3
Lenhoff, A.M.4
Roberts, C.J.5
-
75
-
-
47049116773
-
Chymotrypsin-poly vinyl sulfonate interaction studied by dynamic light scattering and turbidimetric approaches
-
Boeris V, Spelzini D, Salgado JP, Pico G, Romanini D, Farruggia B. 2008. Chymotrypsin-poly vinyl sulfonate interaction studied by dynamic light scattering and turbidimetric approaches. Biochim Biophys Acta 1780 (9): 1032-1037.
-
(2008)
Biochim Biophys Acta.
, vol.1780
, Issue.9
, pp. 1032-1037
-
-
Boeris, V.1
Spelzini, D.2
Salgado, J.P.3
Pico, G.4
Romanini, D.5
Farruggia, B.6
-
76
-
-
0032102646
-
Stabilizers against heat-induced aggregation of RPR 114849, an acidic fibroblast growth factor (AFGF)
-
Won CM, Molnar TE, McKean RE, Spenlehauer GA. 1998. Stabilizers against heat-induced aggregation of RPR 114849, an acidic fibroblast growth factor (AFGF). Int J Pharm 167: 25-36.
-
(1998)
Int J Pharm.
, vol.167
, pp. 25-36
-
-
Won, C.M.1
Molnar, T.E.2
McKean, R.E.3
Spenlehauer, G.A.4
-
77
-
-
22744435459
-
Anion binding and controlled aggregation of human interleukin-1 receptor antagonist
-
Raibekas AA, Bures EJ, Siska CC, Kohno T, Latypov RF, Kerwin BA. 2005. Anion binding and controlled aggregation of human interleukin-1 receptor antagonist. Biochemistry (Mosc) 44 (29): 9871-9879.
-
(2005)
Biochemistry (Mosc).
, vol.44
, Issue.29
, pp. 9871-9879
-
-
Raibekas, A.A.1
Bures, E.J.2
Siska, C.C.3
Kohno, T.4
Latypov, R.F.5
Kerwin, B.A.6
-
78
-
-
35848947730
-
Thermal aggregation of alpha-chymotrypsin: Role of hydrophobic and electrostatic interactions
-
Rezaei-Ghaleh N, Ramshini H, Ebrahim HA, Moosavi MAA, Nemat GM. 2008. Thermal aggregation of alpha-chymotrypsin: Role of hydrophobic and electrostatic interactions. Biophys Chem 132 (1): 23-32.
-
(2008)
Biophys Chem.
, vol.132
, Issue.1
, pp. 23-32
-
-
Rezaei-Ghaleh, N.1
Ramshini, H.2
Ebrahim, H.A.3
Moosavi, M.A.A.4
Nemat, G.M.5
-
79
-
-
0027273987
-
Aggregation and denaturation of apomyoglobin in aqueous urea solutions
-
De Young LR, Dill KA, Fink AL. 1993. Aggregation and denaturation of apomyoglobin in aqueous urea solutions. Biochemistry 32 (15): 3877-3886.
-
(1993)
Biochemistry.
, vol.32
, Issue.15
, pp. 3877-3886
-
-
De Young, L.R.1
Dill, K.A.2
Fink, A.L.3
-
80
-
-
0141750565
-
Kinetics of heat-and acidification-induced aggregation of firefly luciferase
-
Wang K, Kurganov BI. 2003. Kinetics of heat-and acidification-induced aggregation of firefly luciferase. Biophys Chem 106 (2): 97-109.
-
(2003)
Biophys Chem.
, vol.106
, Issue.2
, pp. 97-109
-
-
Wang, K.1
Kurganov, B.I.2
-
81
-
-
21344466724
-
Single particle detection and characterization of synuclein co-aggregation
-
Giese A, Bader B, Bieschke J, Schaffar G, Odoy S, Kahle PJ, Haass C, Kretzschmar H. 2005. Single particle detection and characterization of synuclein co-aggregation. Biochem Biophys Res Commun 333 (4): 1202-1210.
-
(2005)
Biochem Biophys Res Commun.
, vol.333
, Issue.4
, pp. 1202-1210
-
-
Giese, A.1
Bader, B.2
Bieschke, J.3
Schaffar, G.4
Odoy, S.5
Kahle, P.J.6
Haass, C.7
Kretzschmar, H.8
-
82
-
-
33846358473
-
Kinetic studies of protein L aggregation and disaggregation
-
Cellmer T, Douma R, Huebner A, Prausnitz J, Blanch H. 2007. Kinetic studies of protein L aggregation and disaggregation. Biophys Chem 125 (2-3): 350-359.
-
(2007)
Biophys Chem.
, vol.125
, Issue.2-3
, pp. 350-359
-
-
Cellmer, T.1
Douma, R.2
Huebner, A.3
Prausnitz, J.4
Blanch, H.5
-
83
-
-
0037070365
-
Heat-induced gels of egg white/ovalbumins from five avian species: Thermal aggregation, molecular forces involved, and rheological properties
-
Sun Y, Hayakawa S. 2002. Heat-induced gels of egg white/ovalbumins from five avian species: Thermal aggregation, molecular forces involved, and rheological properties. J Agric Food Chem 50 (6): 1636-1642.
-
(2002)
J Agric Food Chem.
, vol.50
, Issue.6
, pp. 1636-1642
-
-
Sun, Y.1
Hayakawa, S.2
-
84
-
-
0026004620
-
Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces
-
Sluzky V, Tamada JA, Klibanov AM, Langer R. 1991. Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces. Proc Natl Acad Sci U S A 88: 9377-9381.
-
(1991)
Proc Natl Acad Sci U S A.
, vol.88
, pp. 9377-9381
-
-
Sluzky, V.1
Tamada, J.A.2
Klibanov, A.M.3
Langer, R.4
-
85
-
-
0026698922
-
Mechanism of insulin aggregation and stabilization in agitated aqueous solutions
-
Sluzky V, Klibanov AM, Langer R. 1992. Mechanism of insulin aggregation and stabilization in agitated aqueous solutions. Biotechnol Bioeng 40: 895-903.
-
(1992)
Biotechnol Bioeng.
, vol.40
, pp. 895-903
-
-
Sluzky, V.1
Klibanov, A.M.2
Langer, R.3
-
86
-
-
0028931574
-
Evidence for a common intermediate in insulin deamidation and covalent dimer formation: Effects of pH and aniline trapping in dilute acidic solutions
-
Darrington RT, Anderson BD. 1995. Evidence for a common intermediate in insulin deamidation and covalent dimer formation: Effects of pH and aniline trapping in dilute acidic solutions. J Pharm Sci 84: 275-282.
-
(1995)
J Pharm Sci.
, vol.84
, pp. 275-282
-
-
Darrington, R.T.1
Anderson, B.D.2
-
87
-
-
0027955039
-
Moisture-induced aggregation of lyophilized insulin
-
Costantino HR, Langer R, Klibanov AM. 1994. Moisture-induced aggregation of lyophilized insulin. Pharm Res 11: 21-29.
-
(1994)
Pharm Res.
, vol.11
, pp. 21-29
-
-
Costantino, H.R.1
Langer, R.2
Klibanov, A.M.3
-
88
-
-
0026659078
-
Chemical stability of insulin. 2. Formation of higher molecular weight transformation products during storage of pharmaceutical preparations
-
Brange J, Havelund S, Hougaard P. 1992. Chemical stability of insulin. 2. Formation of higher molecular weight transformation products during storage of pharmaceutical preparations. Pharm Res 9 (6): 727-734.
-
(1992)
Pharm Res.
, vol.9
, Issue.6
, pp. 727-734
-
-
Brange, J.1
Havelund, S.2
Hougaard, P.3
-
89
-
-
0028576509
-
Approaches to analysis of aggregates and demonstrating mass balance in pharmaceutical protein (basic fibroblast growth factor) formulations
-
Shahrokh Z, Stratton PR, Eberlein GA, Wang YJ. 1994. Approaches to analysis of aggregates and demonstrating mass balance in pharmaceutical protein (basic fibroblast growth factor) formulations. J Pharm Sci 83 (12): 1645-1650.
-
(1994)
J Pharm Sci.
, vol.83
, Issue.12
, pp. 1645-1650
-
-
Shahrokh, Z.1
Stratton, P.R.2
Eberlein, G.A.3
Wang, Y.J.4
-
90
-
-
32344448608
-
Protein aggregation and amyloidosis: Confusion of the kinds?
-
Rousseau F, Schymkowitz J, Serrano L. 2006. Protein aggregation and amyloidosis: Confusion of the kinds? Curr Opin Struct Biol 16 (1): 118-126.
-
(2006)
Curr Opin Struct Biol.
, vol.16
, Issue.1
, pp. 118-126
-
-
Rousseau, F.1
Schymkowitz, J.2
Serrano, L.3
-
91
-
-
84858613793
-
Wikipedia
-
Wikipedia. 2009. Available at http://enwikipediaorg/wiki/Thermodynamic_ temperature.
-
(2009)
-
-
-
92
-
-
38549147909
-
Determining accurate molecular sizes in solution through NMR diffusion spectroscopy
-
Macchioni A, Ciancaleoni G, Zuccaccia C, Zuccaccia D. 2008. Determining accurate molecular sizes in solution through NMR diffusion spectroscopy. Chem Soc Rev 37 (3): 479-489.
-
(2008)
Chem Soc Rev.
, vol.37
, Issue.3
, pp. 479-489
-
-
Macchioni, A.1
Ciancaleoni, G.2
Zuccaccia, C.3
Zuccaccia, D.4
-
93
-
-
0025370815
-
Dominant forces in protein folding
-
Dill KA. 1990. Dominant forces in protein folding. Biochemistry 29 (31): 7133-7155.
-
(1990)
Biochemistry.
, vol.29
, Issue.31
, pp. 7133-715
-
-
Dill, K.A.1
-
94
-
-
0034717156
-
Stability and stabilization of globular proteins in solution
-
Jaenicke R. 2000. Stability and stabilization of globular proteins in solution. J Biotechnol 79 (3): 193-203.
-
(2000)
J Biotechnol.
, vol.79
, Issue.3
, pp. 193-203
-
-
Jaenicke, R.1
-
95
-
-
0030059689
-
Forces contributing to the conformational stability of proteins
-
Pace CN, Shirley BA, McNutt M, Gajiwala K. 1996. Forces contributing to the conformational stability of proteins. FASEB J 10 (1): 75-83.
-
(1996)
FASEB J.
, vol.10
, Issue.1
, pp. 75-83
-
-
Pace, C.N.1
Shirley, B.A.2
McNutt, M.3
Gajiwala, K.4
-
96
-
-
36749084004
-
Protein folding: Then and now
-
Chen Y, Ding F, Nie H, Serohijos AW, Sharma S, Wilcox KC, Yin S, Dokholyan NV. 2008. Protein folding: Then and now. Arch Biochem Biophys 469 (1): 4-19.
-
(2008)
Arch Biochem Biophys.
, vol.469
, Issue.1
, pp. 4-19
-
-
Chen, Y.1
Ding, F.2
Nie, H.3
Serohijos, A.W.4
Sharma, S.5
Wilcox, K.C.6
Yin, S.7
Dokholyan, N.V.8
-
97
-
-
44349104231
-
Refinement of noncalorimetric determination of the change in heat capacity, DeltaC(p), of protein unfolding and validation across a wide temperature range
-
Talla-Singh D, Stites WE. 2008. Refinement of noncalorimetric determination of the change in heat capacity, DeltaC(p), of protein unfolding and validation across a wide temperature range. Proteins 71 (4): 1607-1616.
-
(2008)
Proteins.
, vol.71
, Issue.4
, pp. 1607-1616
-
-
Talla-Singh, D.1
Stites, W.E.2
-
98
-
-
0035000257
-
Some thermodynamic implications for the thermostability of proteins
-
Rees DC, Robertson AD. 2001. Some thermodynamic implications for the thermostability of proteins. Protein Sci 10 (6): 1187-1194.
-
(2001)
Protein Sci.
, vol.10
, Issue.6
, pp. 1187-1194
-
-
Rees, D.C.1
Robertson, A.D.2
-
99
-
-
0026320508
-
Protein stability and molecular adaptation to extreme conditions
-
Jaenicke R. 1991. Protein stability and molecular adaptation to extreme conditions. Eur J Biochem 202 (3): 715-728.
-
(1991)
Eur J Biochem.
, vol.202
, Issue.3
, pp. 715-728
-
-
Jaenicke, R.1
-
100
-
-
52649110660
-
Suppression of insulin aggregation by heparin
-
Giger K, Vanam RP, Seyrek E, Dubin PL. 2008. Suppression of insulin aggregation by heparin. Biomacromolecules 9 (9): 2338-2344.
-
(2008)
Biomacromolecules.
, vol.9
, Issue.9
, pp. 2338-2344
-
-
Giger, K.1
Vanam, R.P.2
Seyrek, E.3
Dubin, P.L.4
-
101
-
-
33846037870
-
Characterization of protein aggregation: The case of a therapeutic immunoglobulin
-
Demeule B, Lawrence MJ, Drake AF, Gurny R, Arvinte T. 2007. Characterization of protein aggregation: The case of a therapeutic immunoglobulin. Biochim Biophys Acta 1774 (1): 146-153.
-
(2007)
Biochim Biophys Acta.
, vol.1774
, Issue.1
, pp. 146-153
-
-
Demeule, B.1
Lawrence, M.J.2
Drake, A.F.3
Gurny, R.4
Arvinte, T.5
-
102
-
-
0001109729
-
Formation of intermolecular b-sheet structure during heat denaturation of ovalbumin
-
Kato A, Takagi T. 1988. Formation of intermolecular b-sheet structure during heat denaturation of ovalbumin. J Agric Food Chem 36: 1156-1159.
-
(1988)
J Agric Food Chem.
, vol.36
, pp. 1156-1159
-
-
Kato, A.1
Takagi, T.2
-
103
-
-
0039129406
-
Secondary structure and oligomerization behavior of equilibrium unfolding intermediates of the lambda cro repressor
-
Fabian H, Falber K, Gast K, Reinstadler D, Rogov VV, Naumann D, Zamyatkin DF, Filimonov VV. 1999. Secondary structure and oligomerization behavior of equilibrium unfolding intermediates of the lambda cro repressor. Biochemistry 38 (17): 5633-5642.
-
(1999)
Biochemistry.
, vol.38
, Issue.17
, pp. 5633-5642
-
-
Fabian, H.1
Falber, K.2
Gast, K.3
Reinstadler, D.4
Rogov, V.V.5
Naumann, D.6
Zamyatkin, D.F.7
Filimonov, V.V.8
-
104
-
-
0026694609
-
Enhancement of the stability of thrombin by polyols: Microcalorimetric studies
-
Boctor AM, Mehta SC. 1992. Enhancement of the stability of thrombin by polyols: Microcalorimetric studies. J Pharm Pharmacol 44 (7): 600-603.
-
(1992)
J Pharm Pharmacol.
, vol.44
, Issue.7
, pp. 600-603
-
-
Boctor, A.M.1
Mehta, S.C.2
-
105
-
-
0027228385
-
Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone
-
Charman SA, Mason KL, Charman WN. 1993. Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone. Pharm Res 10 (7): 954-962.
-
(1993)
Pharm Res.
, vol.10
, Issue.7
, pp. 954-962
-
-
Charman, S.A.1
Mason, K.L.2
Charman, W.N.3
-
106
-
-
0032982258
-
Reversibility of heat-induced denaturation of the recombinant human megakaryocyte growth and development factor
-
Narhi LO, Philo JS, Sun B, Chang BS, Arakawa T. 1999. Reversibility of heat-induced denaturation of the recombinant human megakaryocyte growth and development factor. Pharm Res 16 (6): 799-807.
-
(1999)
Pharm Res.
, vol.16
, Issue.6
, pp. 799-807
-
-
Narhi, L.O.1
Philo, J.S.2
Sun, B.3
Chang, B.S.4
Arakawa, T.5
-
107
-
-
12544259221
-
Reversal of protein aggregation provides evidence for multiple aggregated States
-
Calamai M, Canale C, Relini A, Stefani M, Chiti F, Dobson CM. 2005. Reversal of protein aggregation provides evidence for multiple aggregated States. J Mol Biol 346 (2): 603-616.
-
(2005)
J Mol Biol.
, vol.346
, Issue.2
, pp. 603-616
-
-
Calamai, M.1
Canale, C.2
Relini, A.3
Stefani, M.4
Chiti, F.5
Dobson, C.M.6
-
108
-
-
0037150072
-
Aggregation of granulocyte colony stimulating factor under physiological conditions: Characterization and thermodynamic inhibition
-
Krishnan S, Chi EY, Webb JN, Chang BS, Shan D, Goldenberg M, Manning MC, Randolph TW, Carpenter JF. 2002. Aggregation of granulocyte colony stimulating factor under physiological conditions: Characterization and thermodynamic inhibition. Biochemistry 41 (20): 6422-6431.
-
(2002)
Biochemistry.
, vol.41
, Issue.20
, pp. 6422-6431
-
-
Krishnan, S.1
Chi, E.Y.2
Webb, J.N.3
Chang, B.S.4
Shan, D.5
Goldenberg, M.6
Manning, M.C.7
Randolph, T.W.8
Carpenter, J.F.9
-
109
-
-
0027987422
-
Aggregation pathway of recombinant human keratinocyte growth factor and its stabilization
-
Chen BL, Arakawa T, Morris CF, Kenney WC, Wells CM, Pitt CG. 1994. Aggregation pathway of recombinant human keratinocyte growth factor and its stabilization. Pharm Res 11 (11): 1581-1587.
-
(1994)
Pharm Res.
, vol.11
, Issue.11
, pp. 1581-1587
-
-
Chen, B.L.1
Arakawa, T.2
Morris, C.F.3
Kenney, W.C.4
Wells, C.M.5
Pitt, C.G.6
-
110
-
-
0030629665
-
Insulin formulation and delivery
-
Brange J, Langkjaer L. 1997. Insulin formulation and delivery. Pharm Biotechnol 10: 343-409.
-
(1997)
Pharm Biotechnol.
, vol.10
, pp. 343-409
-
-
Brange, J.1
Langkjaer, L.2
-
111
-
-
25444489351
-
Turbidity as a probe of tubulin polymerization kinetics: A theoretical and experimental re-examination
-
Hall D, Minton AP. 2005. Turbidity as a probe of tubulin polymerization kinetics: A theoretical and experimental re-examination. Anal Biochem 345 (2): 198-213.
-
(2005)
Anal Biochem.
, vol.345
, Issue.2
, pp. 198-213
-
-
Hall, D.1
Minton, A.P.2
-
112
-
-
14344262955
-
Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation
-
Chi EY, Weickmann J, Carpenter JF, Manning MC, Randolph TW. 2005. Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation. J Pharm Sci 94 (2): 256-274.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.2
, pp. 256-274
-
-
Chi, E.Y.1
Weickmann, J.2
Carpenter, J.F.3
Manning, M.C.4
Randolph, T.W.5
-
113
-
-
33144466335
-
Population balance modeling of aggregation kinetics of recombinant human interleukin-1 receptor antagonist
-
Chi EY, Kendrick BS, Carpenter JF, Randolph TW. 2005. Population balance modeling of aggregation kinetics of recombinant human interleukin-1 receptor antagonist. J Pharm Sci 94 (12): 2735-2748.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.12
, pp. 2735-2748
-
-
Chi, E.Y.1
Kendrick, B.S.2
Carpenter, J.F.3
Randolph, T.W.4
-
114
-
-
33645451427
-
Temperature dependence of benzyl alcohol-and 8-anilinonaphthalene-1-sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist
-
Roy S, Katayama D, Dong A, Kerwin BA, Randolph TW, Carpenter JF. 2006. Temperature dependence of benzyl alcohol-and 8-anilinonaphthalene-1-sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist. Biochemistry (Mosc) 45 (12): 3898-3911.
-
(2006)
Biochemistry (Mosc).
, vol.45
, Issue.12
, pp. 3898-3911
-
-
Roy, S.1
Katayama, D.2
Dong, A.3
Kerwin, B.A.4
Randolph, T.W.5
Carpenter, J.F.6
-
115
-
-
0346846691
-
Influence of histidine on the stability and physical properties of a fully human antibody in aqueous and solid forms
-
Chen B, Bautista R, Yu K, Zapata GA, Chamow SM. 2003. Influence of histidine on the stability and physical properties of a fully human antibody in aqueous and solid forms. Pharm Res 20 (12): 1952-1960.
-
(2003)
Pharm Res.
, vol.20
, Issue.12
, pp. 1952-1960
-
-
Chen, B.1
Bautista, R.2
Yu, K.3
Zapata, G.A.4
Chamow, S.M.5
-
116
-
-
0025689597
-
Analytical approaches to the study of monoclonal antibody stability
-
Jiskoot W, Beuvery EC, de Koning AAM, Herron JN, Crommelin DJA. 1990. Analytical approaches to the study of monoclonal antibody stability. Pharm Res 7: 1234-1241.
-
(1990)
Pharm Res.
, vol.7
, pp. 1234-1241
-
-
Jiskoot, W.1
Beuvery, E.C.2
De Koning, A.A.M.3
Herron, J.N.4
Crommelin, D.J.A.5
-
118
-
-
1842555298
-
Effects of sucrose on rFVIIa aggregation and methionine oxidation
-
Soenderkaer S, Carpenter JF, Van De Weert M, Hansen LL, Flink J, Frokjaer S. 2004. Effects of sucrose on rFVIIa aggregation and methionine oxidation. Eur J Pharm Sci 21 (5): 597-606.
-
(2004)
Eur J Pharm Sci.
, vol.21
, Issue.5
, pp. 597-606
-
-
Soenderkaer, S.1
Carpenter, J.F.2
Van De Weert, M.3
Hansen, L.L.4
Flink, J.5
Frokjaer, S.6
-
119
-
-
0032709317
-
Factors affecting the dissociation and aggregation of human interferon gamma
-
Zlateva T, Boteva R, Salvato B, Tsanev R. 1999. Factors affecting the dissociation and aggregation of human interferon gamma. Int J Biol Macromol 26 (5): 357-362.
-
(1999)
Int J Biol Macromol.
, vol.26
, Issue.5
, pp. 357-362
-
-
Zlateva, T.1
Boteva, R.2
Salvato, B.3
Tsanev, R.4
-
120
-
-
38949216069
-
Effect of trehalose on W7FW14F apomyoglobin and insulin fibrillization: New insight into inhibition activity
-
Vilasi S, Iannuzzi C, Portaccio M, Irace G, Sirangelo I. 2008. Effect of trehalose on W7FW14F apomyoglobin and insulin fibrillization: New insight into inhibition activity. Biochemistry (Mosc) 47 (6): 1789-1796.
-
(2008)
Biochemistry (Mosc).
, vol.47
, Issue.6
, pp. 1789-1796
-
-
Vilasi, S.1
Iannuzzi, C.2
Portaccio, M.3
Irace, G.4
Sirangelo, I.5
-
121
-
-
17144422829
-
Denaturation and aggregation of three alpha-lactalbumin preparations at neutral pH
-
McGuffey MK, Epting KL, Kelly RM, Foegeding EA. 2005. Denaturation and aggregation of three alpha-lactalbumin preparations at neutral pH. J Agric Food Chem 53 (8): 3182-3190.
-
(2005)
J Agric Food Chem.
, vol.53
, Issue.8
, pp. 3182-3190
-
-
McGuffey, M.K.1
Epting, K.L.2
Kelly, R.M.3
Foegeding, E.A.4
-
122
-
-
1542345526
-
Protein thermal aggregation involves distinct regions: Sequential events in the heat-induced unfolding and aggregation of hemoglobin
-
Yan YB, Wang Q, He HW, Zhou HM. 2004. Protein thermal aggregation involves distinct regions: Sequential events in the heat-induced unfolding and aggregation of hemoglobin. Biophys J 86 (3): 1682-1690.
-
(2004)
Biophys J.
, vol.86
, Issue.3
, pp. 1682-1690
-
-
Yan, Y.B.1
Wang, Q.2
He, H.W.3
Zhou, H.M.4
-
123
-
-
0242299773
-
pH-dependent aggregation of oligomeric Artocarpus hirsuta lectin on thermal denaturation
-
Gaikwad SM, Khan MI. 2003. pH-dependent aggregation of oligomeric Artocarpus hirsuta lectin on thermal denaturation. Biochem Biophys Res Commun 311 (2): 254-257.
-
(2003)
Biochem Biophys Res Commun.
, vol.311
, Issue.2
, pp. 254-257
-
-
Gaikwad, S.M.1
Khan, M.I.2
-
124
-
-
42549129620
-
The mechanisms underlying the effect 186 AGGREGATION OF THERAPEUTIC PROTEINS of alpha-cyclodextrin on the aggregation and stability of alcohol dehydrogenase
-
Barzegar A, Moosavi-Movahedi AA, Rezaei-Zarchi S, Saboury AA, Ganjali MR, Norouzi P, Hakimelahi GH, Tsai FY. 2008. The mechanisms underlying the effect 186 AGGREGATION OF THERAPEUTIC PROTEINS of alpha-cyclodextrin on the aggregation and stability of alcohol dehydrogenase. Biotechnol Appl Biochem 49 (Pt 3): 203-211.
-
(2008)
Biotechnol Appl Biochem.
, vol.49
, Issue.3 PT
, pp. 203-211
-
-
Barzegar, A.1
Moosavi-Movahedi, A.A.2
Rezaei-Zarchi, S.3
Saboury, A.A.4
Ganjali, M.R.5
Norouzi, P.6
Hakimelahi, G.H.7
Tsai, F.Y.8
-
125
-
-
33644499478
-
Monitoring protein aggregation during thermal unfolding in circular dichroism experiments
-
Benjwal S, Verma S, Roehm KH, Gursky O. 2006. Monitoring protein aggregation during thermal unfolding in circular dichroism experiments. Protein Sci 15 (3): 635-639.
-
(2006)
Protein Sci.
, vol.15
, Issue.3
, pp. 635-639
-
-
Benjwal, S.1
Verma, S.2
Roehm, K.H.3
Gursky, O.4
-
126
-
-
43149094397
-
Thermal inactivation, denaturation and aggregation of mitochondrial aspartate aminotransferase
-
Golub NV, Markossian KA, Kasilovich NV, Sholukh MV, Orlov VN, Kurganov BI. 2008. Thermal inactivation, denaturation and aggregation of mitochondrial aspartate aminotransferase. Biophys Chem 135 (1-3): 125-131.
-
(2008)
Biophys Chem.
, vol.135
, Issue.1-3
, pp. 125-131
-
-
Golub, N.V.1
Markossian, K.A.2
Kasilovich, N.V.3
Sholukh, M.V.4
Orlov, V.N.5
Kurganov, B.I.6
-
127
-
-
7444240973
-
Sorbitol prevents the self-aggregation of unfolded lysozyme leading to an up to 13°C stabilisation of the folded form
-
Petersen SB, Jonson V, Fojan P, Wimmer R, Pedersen S. 2004. Sorbitol prevents the self-aggregation of unfolded lysozyme leading to an up to 13°C stabilisation of the folded form. J Biotechnol 114 (3): 269-278.
-
(2004)
J Biotechnol.
, vol.114
, Issue.3
, pp. 269-278
-
-
Petersen, S.B.1
Jonson, V.2
Fojan, P.3
Wimmer, R.4
Pedersen, S.5
-
128
-
-
34247477705
-
Effect of polyanions on the structure and stability of repifermin (keratinocyte growth factor-2)
-
Derrick T, Grillo AO, Vitharana SN, Jones L, Rexroad J, Shah A, Perkins M, Spitznagel TM, Middaugh CR. 2007. Effect of polyanions on the structure and stability of repifermin (keratinocyte growth factor-2). J Pharm Sci 96 (4): 761-776.
-
(2007)
J Pharm Sci.
, vol.96
, Issue.4
, pp. 761-776
-
-
Derrick, T.1
Grillo, A.O.2
Vitharana, S.N.3
Jones, L.4
Rexroad, J.5
Shah, A.6
Perkins, M.7
Spitznagel, T.M.8
Middaugh, C.R.9
-
129
-
-
11244340520
-
Thermally induced fibrillar aggregation of hen egg white lysozyme
-
Arnaudov LN, de Vries R. 2005. Thermally induced fibrillar aggregation of hen egg white lysozyme. Biophys J 88 (1): 515-526.
-
(2005)
Biophys J.
, vol.88
, Issue.1
, pp. 515-526
-
-
Arnaudov, L.N.1
De Vries, R.2
-
130
-
-
34250855118
-
Amidated amino acids are prominent additives for preventing heat-induced aggregation of lysozyme
-
Matsuoka T, Tomita S, Hamada H, Shiraki K. 2007. Amidated amino acids are prominent additives for preventing heat-induced aggregation of lysozyme. J Biosci Bioeng 103 (5): 440-443.
-
(2007)
J Biosci Bioeng.
, vol.103
, Issue.5
, pp. 440-443
-
-
Matsuoka, T.1
Tomita, S.2
Hamada, H.3
Shiraki, K.4
-
131
-
-
34548210324
-
Aggregation and fibrillation of bovine serum albumin
-
Holm NK, Jespersen SK, Thomassen LV, Wolff TY, Pankaj S, Thomsen LA, Christiansen G, Andersen CB, Knudsen AD, Otzen DE. 2007. Aggregation and fibrillation of bovine serum albumin. BBA-Proteins Proteom 1774 (9): 1128-1138.
-
(2007)
BBA-Proteins Proteom.
, vol.1774
, Issue.9
, pp. 1128-1138
-
-
Holm, N.K.1
Jespersen, S.K.2
Thomassen, L.V.3
Wolff, T.Y.4
Pankaj, S.5
Thomsen, L.A.6
Christiansen, G.7
Andersen, C.B.8
Knudsen, A.D.9
Otzen, D.E.10
-
132
-
-
32644434554
-
Influence of aggregation on immunogenicity of recombinant human factor VIII in hemophilia A mice
-
Purohit VS, Middaugh CR, Balasubramanian SV. 2006. Influence of aggregation on immunogenicity of recombinant human factor VIII in hemophilia A mice. J Pharm Sci 95 (2): 358-371.
-
(2006)
J Pharm Sci.
, vol.95
, Issue.2
, pp. 358-371
-
-
Purohit, V.S.1
Middaugh, C.R.2
Balasubramanian, S.V.3
-
133
-
-
39749110693
-
Nucleation, growth, and activation energies for seeded and unseeded aggregation of alpha-chymotrypsinogen A
-
Andrews JM, Weiss WF, Roberts CJ. 2008. Nucleation, growth, and activation energies for seeded and unseeded aggregation of alpha-chymotrypsinogen A. Biochemistry (Mosc) 47 (8): 2397-2403.
-
(2008)
Biochemistry (Mosc).
, vol.47
, Issue.8
, pp. 2397-2403
-
-
Andrews, J.M.1
Weiss, W.F.2
Roberts, C.J.3
-
134
-
-
33645282235
-
Change in kinetic regime of protein aggregation with temperature increase. Thermal aggregation of rabbit muscle creatine kinase
-
Fedurkina NV, Belousova LV, Mitskevich LG, Zhou HM, Chang Z, Kurganov BI. 2006. Change in kinetic regime of protein aggregation with temperature increase. Thermal aggregation of rabbit muscle creatine kinase. Biochemistry (Mosc) 71 (3): 325-331.
-
(2006)
Biochemistry (Mosc)
, vol.71
, Issue.3
, pp. 325-331
-
-
Fedurkina, N.V.1
Belousova, L.V.2
Mitskevich, L.G.3
Zhou, H.M.4
Chang, Z.5
Kurganov, B.I.6
-
135
-
-
0034076282
-
The thermal stability of immunoglobulin: Unfolding and aggregation of a multi-domain protein
-
Vermeer AW, Norde W. 2000. The thermal stability of immunoglobulin: Unfolding and aggregation of a multi-domain protein. Biophys J 78 (1): 394-404.
-
(2000)
Biophys J.
, vol.78
, Issue.1
, pp. 394-404
-
-
Vermeer, A.W.1
Norde, W.2
-
136
-
-
33745664260
-
The thermal behaviour of enzyme activity: Implications for biotechnology
-
Eisenthal R, Peterson ME, Daniel RM, Danson MJ. 2006. The thermal behaviour of enzyme activity: Implications for biotechnology. Trends Biotechnol 24 (7): 289-292.
-
(2006)
Trends Biotechnol.
, vol.24
, Issue.7
, pp. 289-292
-
-
Eisenthal, R.1
Peterson, M.E.2
Daniel, R.M.3
Danson, M.J.4
-
137
-
-
33846219578
-
Denaturation and aggregation processes in thermal gelation of whey proteins resolved by differential scanning calorimetry
-
Fitzsimons SM, Mulvihill DM, Morris ER. 2007. Denaturation and aggregation processes in thermal gelation of whey proteins resolved by differential scanning calorimetry. Food Hydrocolloids 21 (4): 638-644.
-
(2007)
Food Hydrocolloids.
, vol.21
, Issue.4
, pp. 638-644
-
-
Fitzsimons, S.M.1
Mulvihill, D.M.2
Morris, E.R.3
-
138
-
-
38149037129
-
Ultrasonic rheology of a monoclonal antibody (IgG2) solution: Implications for physical stability of proteins in high concentration formulations
-
Saluja A, Badkar AV, Zeng DL, Kalonia DS. 2007. Ultrasonic rheology of a monoclonal antibody (IgG2) solution: Implications for physical stability of proteins in high concentration formulations. J Pharm Sci 96 (12): 3181-3195.
-
(2007)
J Pharm Sci.
, vol.96
, Issue.12
, pp. 3181-3195
-
-
Saluja, A.1
Badkar, A.V.2
Zeng, D.L.3
Kalonia, D.S.4
-
139
-
-
0029040518
-
NMR study of the cold, heat, and pressure unfolding of ribonuclease A
-
Zhang J, Peng X, Jonas A, Jonas J. 1995. NMR study of the cold, heat, and pressure unfolding of ribonuclease A. Biochemistry 34 (27): 8631-8641.
-
(1995)
Biochemistry.
, vol.34
, Issue.27
, pp. 8631-8641
-
-
Zhang, J.1
Peng, X.2
Jonas, A.3
Jonas, J.4
-
140
-
-
0031896612
-
Species differences of serum albumins: II. Chemical and thermal stability
-
Kosa T, Maruyama T, Otagiri M. 1998. Species differences of serum albumins: II. Chemical and thermal stability. Pharm Res 15 (3): 449-454.
-
(1998)
Pharm Res.
, vol.15
, Issue.3
, pp. 449-454
-
-
Kosa, T.1
Maruyama, T.2
Otagiri, M.3
-
142
-
-
0036760452
-
Crystal structures of human antibodies: A detailed and unfinished tapestry of immunoglobulin gene products
-
Ramsland PA, Farrugia W. 2002. Crystal structures of human antibodies: A detailed and unfinished tapestry of immunoglobulin gene products. J Mol Recognit 15 (5): 248-259.
-
(2002)
J Mol Recognit.
, vol.15
, Issue.5
, pp. 248-259
-
-
Ramsland, P.A.1
Farrugia, W.2
-
143
-
-
3242670796
-
Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association
-
Sukumar M, Doyle BL, Combs JL, Pekar AH. 2004. Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association. Pharm Res 21 (7): 1087-1093.
-
(2004)
Pharm Res.
, vol.21
, Issue.7
, pp. 1087-1093
-
-
Sukumar, M.1
Doyle, B.L.2
Combs, J.L.3
Pekar, A.H.4
-
144
-
-
33845410077
-
Sorbitol crystallization can lead to protein aggregation in frozen protein formulations
-
Piedmonte DM, Summers C, McAuley A, Karamujic L, Ratnaswamy G. 2007. Sorbitol crystallization can lead to protein aggregation in frozen protein formulations. Pharm Res 24 (1): 136-146.
-
(2007)
Pharm Res.
, vol.24
, Issue.1
, pp. 136-146
-
-
Piedmonte, D.M.1
Summers, C.2
McAuley, A.3
Karamujic, L.4
Ratnaswamy, G.5
-
145
-
-
0031239857
-
Manipulation of lyophilization-induced phase separation: Implications for pharmaceutical proteins
-
Heller MC, Carpenter JF, Randolph TW. 1997. Manipulation of lyophilization-induced phase separation: Implications for pharmaceutical proteins. Biotechnol Prog 13 (5): 590-596.
-
(1997)
Biotechnol Prog.
, vol.13
, Issue.5
, pp. 590-596
-
-
Heller, M.C.1
Carpenter, J.F.2
Randolph, T.W.3
-
146
-
-
0033586786
-
Protein formulation and lyophilization cycle design: Prevention of damage due to freeze-concentration induced phase separation
-
Heller MC, Carpenter JF, Randolph TW. 1999. Protein formulation and lyophilization cycle design: Prevention of damage due to freeze-concentration induced phase separation. Biotechnol Bioeng 63 (2): 166-174.
-
(1999)
Biotechnol Bioeng.
, vol.63
, Issue.2
, pp. 166-174
-
-
Heller, M.C.1
Carpenter, J.F.2
Randolph, T.W.3
-
147
-
-
11944271430
-
Solubility as a function of protein structure and solvent components
-
Schein CH. 1990. Solubility as a function of protein structure and solvent components. Biotechnology 8: 308-317.
-
(1990)
Biotechnology.
, vol.8
, pp. 308-317
-
-
Schein, C.H.1
-
148
-
-
0031564608
-
Salt effects on protein stability: Two-stranded alpha-helical coiled-coils containing inter-or intrahelical ion pairs
-
Kohn WD, Kay CM, Hodges RS. 1997. Salt effects on protein stability: Two-stranded alpha-helical coiled-coils containing inter-or intrahelical ion pairs. J Mol Biol 267 (4): 1039-1052.
-
(1997)
J Mol Biol.
, vol.267
, Issue.4
, pp. 1039-1052
-
-
Kohn, W.D.1
Kay, C.M.2
Hodges, R.S.3
-
149
-
-
0028341299
-
Thermal stability of low molecular weight urokinase during heat treatment. II. Effect of polymeric additives
-
Vrkljan M, Foster TM, Powers ME, Henkin J, Porter WR, Staack H, Carpenter JF, Manning MC. 1994. Thermal stability of low molecular weight urokinase during heat treatment. II. Effect of polymeric additives. Pharm Res 11 (7): 1004-1008.
-
(1994)
Pharm Res.
, vol.11
, Issue.7
, pp. 1004-1008
-
-
Vrkljan, M.1
Foster, T.M.2
Powers, M.E.3
Henkin, J.4
Porter, W.R.5
Staack, H.6
Carpenter, J.F.7
Manning, M.C.8
-
150
-
-
0030765942
-
Recombinant factor VIII SQ-Influence of oxygen, metal ions, pH and ionic strength on its stability in aqueous solution
-
Fatouros A, Osterberg T, Mikaelsson M. 1997. Recombinant factor VIII SQ-Influence of oxygen, metal ions, pH and ionic strength on its stability in aqueous solution. Int J Pharm 155: 121-131.
-
(1997)
Int J Pharm.
, vol.155
, pp. 121-131
-
-
Fatouros, A.1
Osterberg, T.2
Mikaelsson, M.3
-
151
-
-
0042467550
-
Rationalization of the effects of mutations on peptide and protein aggregation rates
-
Chiti F, Stefani M, Taddei N, Ramponi G, Dobson CM. 2003. Rationalization of the effects of mutations on peptide and protein aggregation rates. Nature 424 (6950): 805-808.
-
(2003)
Nature.
, vol.424
, Issue.6950
, pp. 805-808
-
-
Chiti, F.1
Stefani, M.2
Taddei, N.3
Ramponi, G.4
Dobson, C.M.5
-
152
-
-
3242785264
-
Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains
-
DuBay KF, Pawar AP, Chiti F, Zurdo J, Dobson CM, Vendruscolo M. 2004. Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains. J Mol Biol 341 (5): 1317-1326.
-
(2004)
J Mol Biol.
, vol.341
, Issue.5
, pp. 1317-1326
-
-
DuBay, K.F.1
Pawar, A.P.2
Chiti, F.3
Zurdo, J.4
Dobson, C.M.5
Vendruscolo, M.6
-
153
-
-
38749126403
-
pH dependent effect of glycosylation on protein stability
-
Wang W, Antonsen K, Wang YJ, Wang DQ. 2008. pH dependent effect of glycosylation on protein stability. Eur J Pharm Sci 33 (2): 120-127.
-
(2008)
Eur J Pharm Sci.
, vol.33
, Issue.2
, pp. 120-127
-
-
Wang, W.1
Antonsen, K.2
Wang, Y.J.3
Wang, D.Q.4
-
154
-
-
1642456636
-
Characterization and analysis of thermal denaturation of antibodies by size exclusion high-performance liquid chromatography with quadruple detection
-
Hartmann WK, Saptharishi N, Yang XY, Mitra G, Soman G. 2004. Characterization and analysis of thermal denaturation of antibodies by size exclusion high-performance liquid chromatography with quadruple detection. Anal Biochem 325 (2): 227-239.
-
(2004)
Anal Biochem.
, vol.325
, Issue.2
, pp. 227-239
-
-
Hartmann, W.K.1
Saptharishi, N.2
Yang, X.Y.3
Mitra, G.4
Soman, G.5
-
155
-
-
0031660957
-
Effects of Tween 80 and sucrose on acute short-term stability and long-term storage at-20 degrees C of a recombinant hemoglobin
-
Kerwin BA, Heller MC, Levin SH, Randolph TW. 1998. Effects of Tween 80 and sucrose on acute short-term stability and long-term storage at-20 degrees C of a recombinant hemoglobin. J Pharm Sci 87 (9): 1062-1068.
-
(1998)
J Pharm Sci.
, vol.87
, Issue.9
, pp. 1062-1068
-
-
Kerwin, B.A.1
Heller, M.C.2
Levin, S.H.3
Randolph, T.W.4
-
156
-
-
0029077350
-
The effect of pH and temperature on the self-association of recombinant human interleukin-2 as studied by equilibrium sedimentation
-
Advant SJ, Braswell EH, Kumar CV, Kalonia DS. 1995. The effect of pH and temperature on the self-association of recombinant human interleukin-2 as studied by equilibrium sedimentation. Pharm Res 12 (5): 637-641.
-
(1995)
Pharm Res.
, vol.12
, Issue.5
, pp. 637-641
-
-
Advant, S.J.1
Braswell, E.H.2
Kumar, C.V.3
Kalonia, D.S.4
-
157
-
-
0032486770
-
I. Study of protein aggregation due to heat denaturation: A structural approach using circular dichroism spectroscopy, nuclear magnetic resonance, and static light scattering
-
Tsai AM, van Zanten JH, Betenbaugh MJ. 1998. I. Study of protein aggregation due to heat denaturation: A structural approach using circular dichroism spectroscopy, nuclear magnetic resonance, and static light scattering. Biotechnol Bioeng 59 (3): 273-280.
-
(1998)
Biotechnol Bioeng.
, vol.59
, Issue.3
, pp. 273-280
-
-
Tsai, A.M.1
Van Zanten, J.H.2
Betenbaugh, M.J.3
-
158
-
-
33745876259
-
Effects of pH, temperature, and sucrose on benzyl alcohol-induced aggregation of recombinant human granulocyte colony stimulating factor
-
Thirumangalathu R, Krishnan S, Brems DN, Randolph TW, Carpenter JF. 2006. Effects of pH, temperature, and sucrose on benzyl alcohol-induced aggregation of recombinant human granulocyte colony stimulating factor. J Pharm Sci 95 (7): 1480-1497.
-
(2006)
J Pharm Sci.
, vol.95
, Issue.7
, pp. 1480-1497
-
-
Thirumangalathu, R.1
Krishnan, S.2
Brems, D.N.3
Randolph, T.W.4
Carpenter, J.F.5
-
159
-
-
57349123585
-
Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations
-
Roy S, Henderson I, Nayar R, Randolph TW, Carpenter JF. 2008. Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations. J Pharm Sci. doi:10.1002/ jps.21409.
-
(2008)
J Pharm Sci
-
-
Roy, S.1
Henderson, I.2
Nayar, R.3
Randolph, T.W.4
Carpenter, J.F.5
-
160
-
-
35348823110
-
Protein aggregation kinetics during protein A chromatography case study for an Fc fusion protein
-
Shukla AA, Gupta P, Han X. 2007. Protein aggregation kinetics during protein A chromatography case study for an Fc fusion protein. J Chromatogr 1171 (1-2): 22-28.
-
(2007)
J Chromatogr.
, vol.1171
, Issue.1-2
, pp. 22-28
-
-
Shukla, A.A.1
Gupta, P.2
Han, X.3
-
161
-
-
33847059215
-
Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies
-
Ejima D, Tsumoto K, Fukada H, Yumioka R, Nagase K, Arakawa T, Philo JS. 2007. Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies. Proteins 66 (4): 954-962.
-
(2007)
Proteins.
, vol.66
, Issue.4
, pp. 954-962
-
-
Ejima, D.1
Tsumoto, K.2
Fukada, H.3
Yumioka, R.4
Nagase, K.5
Arakawa, T.6
Philo, J.S.7
-
162
-
-
0034659694
-
Effect of pH on the structure and aggregation of human glycodelin A. A comparison with beta-lactoglobulin A
-
Barteri M, Gaudiano MC, Rotella S, Benagiano G, Pala A. 2000. Effect of pH on the structure and aggregation of human glycodelin A. A comparison with beta-lactoglobulin A. BBA-Protein Struct M 1479 (12): 255-264.
-
(2000)
BBA-Protein Struct M
, vol.1479
, Issue.12
, pp. 255-264
-
-
Barteri, M.1
Gaudiano, M.C.2
Rotella, S.3
Benagiano, G.4
Pala, A.5
-
163
-
-
50149096820
-
Guiding protein aggregation with macromolecular crowding
-
Munishkina LA, Ahmad A, Fink AL, Uversky VN. 2008. Guiding protein aggregation with macromolecular crowding. Biochemistry 47 (34): 8993-9006.
-
(2008)
Biochemistry
, vol.47
, Issue.34
, pp. 8993-9006
-
-
Munishkina, L.A.1
Ahmad, A.2
Fink, A.L.3
Uversky, V.N.4
-
164
-
-
0029075870
-
Domain structure, stability and domain-domain interactions in recombinant factor XIII
-
Kurochkin IV, Procyk R, Bishop PD, Yee VC, Teller DC, Ingham KC, Medved LV. 1995. Domain structure, stability and domain-domain interactions in recombinant factor XIII. J Mol Biol 248 (2): 414-430.
-
(1995)
J Mol Biol.
, vol.248
, Issue.2
, pp. 414-430
-
-
Kurochkin, I.V.1
Procyk, R.2
Bishop, P.D.3
Yee, V.C.4
Teller, D.C.5
Ingham, K.C.6
Medved, L.V.7
-
165
-
-
33751421851
-
Electrostatically driven protein aggregation: Beta-lactoglobulin at low ionic strength
-
Majhi PR, Ganta RR, Vanam RP, Seyrek E, Giger K, Dubin PL. 2006. Electrostatically driven protein aggregation: Beta-lactoglobulin at low ionic strength. Langmuir 22 (22): 9150-9159.
-
(2006)
Langmuir.
, vol.22
, Issue.22
, pp. 9150-9159
-
-
Majhi, P.R.1
Ganta, R.R.2
Vanam, R.P.3
Seyrek, E.4
Giger, K.5
Dubin, P.L.6
-
166
-
-
33846814867
-
How does dextran sulfate prevent heat induced aggregation of protein? The mechanism and its limitation as aggregation inhibitor
-
Chung K, Kim J, Cho BK, Ko BJ, Hwang BY, Kim BG. 2007. How does dextran sulfate prevent heat induced aggregation of protein? The mechanism and its limitation as aggregation inhibitor. Biochim Biophys Acta 1774 (2): 249-257.
-
(2007)
Biochim Biophys Acta.
, vol.1774
, Issue.2
, pp. 249-257
-
-
Chung, K.1
Kim, J.2
Cho, B.K.3
Ko, B.J.4
Hwang, B.Y.5
Kim, B.G.6
-
167
-
-
37349110384
-
A novel method for study of the aggregation of protein induced by metal ion aluminum(III) using resonance Rayleigh scattering technique
-
Long X, Zhang C, Cheng J, Bi S. 2008. A novel method for study of the aggregation of protein induced by metal ion aluminum(III) using resonance Rayleigh scattering technique. Spectrochim Acta A Mol Biomol Spectrosc 69 (1): 71-77.
-
(2008)
Spectrochim Acta A Mol Biomol Spectrosc.
, vol.69
, Issue.1
, pp. 71-77
-
-
Long, X.1
Zhang, C.2
Cheng, J.3
Bi, S.4
-
168
-
-
43649090986
-
Formation of amyloid fibrils by bovine carbonic anhydrase
-
Rana A, Gupta TP, Bansal S, Kundu B. 2008. Formation of amyloid fibrils by bovine carbonic anhydrase. Biochim Biophys Acta 1784 (6): 930-935.
-
(2008)
Biochim Biophys Acta.
, vol.1784
, Issue.6
, pp. 930-935
-
-
Rana, A.1
Gupta, T.P.2
Bansal, S.3
Kundu, B.4
-
169
-
-
0030329632
-
Formulation development of an antifibrin monoclonal antibody radiopharmaceutical
-
Kamat MS, Tolman GL, Brown JM. 1996. Formulation development of an antifibrin monoclonal antibody radiopharmaceutical. Pharm Biotechnol 9: 343-364.
-
(1996)
Pharm Biotechnol.
, vol.9
, pp. 343-364
-
-
Kamat, M.S.1
Tolman, G.L.2
Brown, J.M.3
-
170
-
-
0025793265
-
The effects of formulation variables on the stability of freeze-dried human growth hormone
-
Pikal MJ, Dellerman KM, Roy ML, Riggin RM. 1991. The effects of formulation variables on the stability of freeze-dried human growth hormone. Pharm Res 8 (4): 427-436.
-
(1991)
Pharm Res.
, vol.8
, Issue.4
, pp. 427-436
-
-
Pikal, M.J.1
Dellerman, K.M.2
Roy, M.L.3
Riggin, R.M.4
-
171
-
-
0028126885
-
Stability of rhbFGF as determined by UV spectroscopic measurements of turbidity
-
Eberlein GA, Stratton PR, Wang YJ. 1994. Stability of rhbFGF as determined by UV spectroscopic measurements of turbidity. PDA J Pharm Sci Technol 48 (5): 224-230.
-
(1994)
PDA J Pharm Sci Technol.
, vol.48
, Issue.5
, pp. 224-230
-
-
Eberlein, G.A.1
Stratton, P.R.2
Wang, Y.J.3
-
172
-
-
0028300715
-
Chemical and physical stability of chimeric L6, a mouse-human monoclonal antibody
-
May
-
Paborji M, Pochopin NL, Coppola WP, Bogardus JB. 1994. Chemical and physical stability of chimeric L6, a mouse-human monoclonal antibody. Pharm Res 11 (May): 764-771.
-
(1994)
Pharm Res.
, vol.11
, pp. 764-771
-
-
Paborji, M.1
Pochopin, N.L.2
Coppola, W.P.3
Bogardus, J.B.4
-
173
-
-
0036549922
-
Salts and glycine increase reversibility and decrease aggregation during thermal unfolding of ribonuclease-A
-
Kita Y, Arakawa T. 2002. Salts and glycine increase reversibility and decrease aggregation during thermal unfolding of ribonuclease-A. Biosci Biotechnol Biochem 66 (4): 880-882.
-
(2002)
Biosci Biotechnol Biochem.
, vol.66
, Issue.4
, pp. 880-882
-
-
Kita, Y.1
Arakawa, T.2
-
174
-
-
2642562735
-
Influence of the ionic strength on the heat-induced aggregation of the globular protein beta-lactoglobulin at pH 7
-
Baussay K, Bon CL, Nicolai T, Durand D, Busnel JP. 2004. Influence of the ionic strength on the heat-induced aggregation of the globular protein beta-lactoglobulin at pH 7. Int J Biol Macromol 34 (1-2): 21-28.
-
(2004)
Int J Biol Macromol.
, vol.34
, Issue.1-2
, pp. 21-28
-
-
Baussay, K.1
Bon, C.L.2
Nicolai, T.3
Durand, D.4
Busnel, J.P.5
-
175
-
-
33846274983
-
Strong impact of ionic strength on the kinetics of fibrilar aggregation of bovine beta-lactoglobulin
-
Arnaudov LN, de Vries R. 2006. Strong impact of ionic strength on the kinetics of fibrilar aggregation of bovine beta-lactoglobulin. Biomacromolecules 7 (12): 3490-3498.
-
(2006)
Biomacromolecules.
, vol.7
, Issue.12
, pp. 3490-3498
-
-
Arnaudov, L.N.1
De Vries, R.2
-
176
-
-
12344310069
-
Confocal microscopy of heat-induced aggregation and gelation of beta-lactoglobulin in presence of non-ionic surfactant
-
Kerstens S, Murray BS, Dickinson E. 2005. Confocal microscopy of heat-induced aggregation and gelation of beta-lactoglobulin in presence of non-ionic surfactant. Food Hydrocolloids 19 (3): 625-633.
-
(2005)
Food Hydrocolloids.
, vol.19
, Issue.3
, pp. 625-633
-
-
Kerstens, S.1
Murray, B.S.2
Dickinson, E.3
-
177
-
-
55749096388
-
Measuring and increasing protein solubility
-
Trevino SR, Scholtz JM, Pace CN. 2008. Measuring and increasing protein solubility. J Pharm Sci 97 (10): 4155-4166.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.10
, pp. 4155-4166
-
-
Trevino, S.R.1
Scholtz, J.M.2
Pace, C.N.3
-
178
-
-
34548717041
-
Solute effects on the irreversible aggregation of serum albumin
-
Bagger HL, Ogendal LH, Westh P. 2007. Solute effects on the irreversible aggregation of serum albumin. Biophys Chem 130 (1-2): 17-25.
-
(2007)
Biophys Chem.
, vol.130
, Issue.1-2
, pp. 17-25
-
-
Bagger, H.L.1
Ogendal, L.H.2
Westh, P.3
-
179
-
-
33845977687
-
Role of electrostatic interactions in 2,2,2-trifluoroethanol-induced structural changes and aggregation of alpha-chymotrypsin
-
Rezaei-Ghaleh N, Ebrahim-Habibi A, Moosavi-Movahedi AA, Nemat-Gorgani M. 2007. Role of electrostatic interactions in 2,2,2-trifluoroethanol-induced structural changes and aggregation of alpha-chymotrypsin. Arch Biochem Biophys 457 (2): 160-169.
-
(2007)
Arch Biochem Biophys.
, vol.457
, Issue.2
, pp. 160-169
-
-
Rezaei-Ghaleh, N.1
Ebrahim-Habibi, A.2
Moosavi-Movahedi, A.A.3
Nemat-Gorgani, M.4
-
180
-
-
34447621390
-
The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin
-
Grudzielanek S, Smirnovas V, Winter R. 2007. The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin. Chem Phys Lipids 149 (1-2): 28-39.
-
(2007)
Chem Phys Lipids.
, vol.149
, Issue.1-2
, pp. 28-39
-
-
Grudzielanek, S.1
Smirnovas, V.2
Winter, R.3
-
181
-
-
33847105134
-
The protective effects of osmolytes on arginine kinase unfolding and aggregation
-
Xia Y, Park YD, Mu H, Zhou HM, Wang XY, Meng FG. 2007. The protective effects of osmolytes on arginine kinase unfolding and aggregation. Int J Biol Macromol 40 (5): 437-443.
-
(2007)
Int J Biol Macromol.
, vol.40
, Issue.5
, pp. 437-443
-
-
Xia, Y.1
Park, Y.D.2
Mu, H.3
Zhou, H.M.4
Wang, X.Y.5
Meng, F.G.6
-
182
-
-
17044405795
-
LEA proteins prevent protein aggregation due to water stress
-
Goyal K, Walton LJ, Tunnacliffe A. 2005. LEA proteins prevent protein aggregation due to water stress. Biochem J 388 (1): 151-157.
-
(2005)
Biochem J.
, vol.388
, Issue.1
, pp. 151-157
-
-
Goyal, K.1
Walton, L.J.2
Tunnacliffe, A.3
-
183
-
-
47949127624
-
Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage
-
Beranger F, Crozet C, Goldsborough A, Lehmann S. 2008. Trehalose impairs aggregation of PrPSc molecules and protects prion-infected cells against oxidative damage. Biochem Biophys Res Commun 374 (1): 44-48.
-
(2008)
Biochem Biophys Res Commun.
, vol.374
, Issue.1
, pp. 44-48
-
-
Beranger, F.1
Crozet, C.2
Goldsborough, A.3
Lehmann, S.4
-
184
-
-
48149093621
-
Stabilization of IgG1 in spray-dried powders for inhalation
-
Schule S, Schulz-Fademrecht T, Garidel P, Bechtold-Peters K, Friess W. 2008. Stabilization of IgG1 in spray-dried powders for inhalation. Eur J Pharm Biopharm 69 (3): 793-807.
-
(2008)
Eur J Pharm Biopharm.
, vol.69
, Issue.3
, pp. 793-807
-
-
Schule, S.1
Schulz-Fademrecht, T.2
Garidel, P.3
Bechtold-Peters, K.4
Friess, W.5
-
185
-
-
33947723675
-
Assessment of temperature effects on beta-aggregation of native and glycated albumin by FTIR spectroscopy and PAGE: Relations between structural changes and antioxidant properties
-
Rondeau P, Armenta S, Caillens H, Chesne S, Bourdon E. 2007. Assessment of temperature effects on beta-aggregation of native and glycated albumin by FTIR spectroscopy and PAGE: Relations between structural changes and antioxidant properties. Arch Biochem Biophys 460 (1): 141-150.
-
(2007)
Arch Biochem Biophys.
, vol.460
, Issue.1
, pp. 141-150
-
-
Rondeau, P.1
Armenta, S.2
Caillens, H.3
Chesne, S.4
Bourdon, E.5
-
186
-
-
0036784648
-
Stabilization of proteins by low molecular weight multi-ions
-
Maclean DS, Qian Q, Middaugh CR. 2002. Stabilization of proteins by low molecular weight multi-ions. J Pharm Sci 91 (10): 2220-2229.
-
(2002)
J Pharm Sci.
, vol.91
, Issue.10
, pp. 2220-2229
-
-
Maclean, D.S.1
Qian, Q.2
Middaugh, C.R.3
-
187
-
-
33746219698
-
Heat denaturation and aggregation of beta-lactoglobulin enriched WPI in the presence of arginine HCl, NaCl and guanidinium HCl at pH 4.0 and 7.0
-
Unterhaslberger G, Schmitt C, Sanchez C, Appolonia NC, Raemy A. 2006. Heat denaturation and aggregation of beta-lactoglobulin enriched WPI in the presence of arginine HCl, NaCl and guanidinium HCl at pH 4.0 and 7.0. Food Hydrocolloids 20 (7): 1006-1019.
-
(2006)
Food Hydrocolloids.
, vol.20
, Issue.7
, pp. 1006-1019
-
-
Unterhaslberger, G.1
Schmitt, C.2
Sanchez, C.3
Appolonia, N.C.4
Raemy, A.5
-
188
-
-
33748588165
-
Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant
-
Ignatova Z, Gierasch LM. 2006. Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant. Proc Natl Acad Sci U S A 103 (36): 13357-13361.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, Issue.36
, pp. 13357-13361
-
-
Ignatova, Z.1
Gierasch, L.M.2
-
189
-
-
24944581330
-
Review: Why is arginine effective in suppressing aggregation?
-
Tsumoto K, Ejima D, Kita Y, Arakawa T. 2005. Review: Why is arginine effective in suppressing aggregation? Protein Pept Lett 12 (7): 613-619.
-
(2005)
Protein Pept Lett.
, vol.12
, Issue.7
, pp. 613-619
-
-
Tsumoto, K.1
Ejima, D.2
Kita, Y.3
Arakawa, T.4
-
190
-
-
42049098161
-
Differences in the effects of solution additives on heat-and refolding-induced aggregation
-
Hamada H, Takahashi R, Noguchi T, Shiraki K. 2008. Differences in the effects of solution additives on heat-and refolding-induced aggregation. Biotechnol Prog 24 (2): 436-443.
-
(2008)
Biotechnol Prog.
, vol.24
, Issue.2
, pp. 436-443
-
-
Hamada, H.1
Takahashi, R.2
Noguchi, T.3
Shiraki, K.4
-
191
-
-
37149051553
-
Effects of arginine on kinetics of protein aggregation studied by dynamic laser light scattering and tubidimetry techniques
-
Lyutova EM, Kasakov AS, Gurvits BY. 2007. Effects of arginine on kinetics of protein aggregation studied by dynamic laser light scattering and tubidimetry techniques. Biotechnol Prog 23 (6): 1411-1416.
-
(2007)
Biotechnol Prog.
, vol.23
, Issue.6
, pp. 1411-1416
-
-
Lyutova, E.M.1
Kasakov, A.S.2
Gurvits, B.Y.3
-
192
-
-
43149117084
-
Inhibition of protein aggregation: Supramolecular assemblies of arginine hold the key
-
Das U, Hariprasad G, Ethayathulla AS, Manral P, Das TK, Pasha S, Mann A, Ganguli M, Verma AK, Bhat R, Chandrayan SK, Ahmed S, Sharma S, Kaur P, Singh TP, Srinivasan A. 2007. Inhibition of protein aggregation: Supramolecular assemblies of arginine hold the key. PLoS One 2 (11): e1176.
-
(2007)
PLoS One.
, vol.2
, Issue.11
-
-
Das, U.1
Hariprasad, G.2
Ethayathulla, A.S.3
Manral, P.4
Das, T.K.5
Pasha, S.6
Mann, A.7
Ganguli, M.8
Verma, A.K.9
Bhat, R.10
Chandrayan, S.K.11
Ahmed, S.12
Sharma, S.13
Kaur, P.14
Singh, T.P.15
Srinivasan, A.16
-
193
-
-
35748959041
-
Effects of osmolytes on protein folding and aggregation in cells
-
Ignatova Z, Gierasch LM. 2007. Effects of osmolytes on protein folding and aggregation in cells. Methods Enzymol 428: 355-372.
-
(2007)
Methods Enzymol.
, vol.428
, pp. 355-372
-
-
Ignatova, Z.1
Gierasch, L.M.2
-
194
-
-
37549046467
-
Enhancement of thermal stability and inhibition of protein aggregation by osmolytic effect of hydroxyproline
-
Kar K, Kishore N. 2007. Enhancement of thermal stability and inhibition of protein aggregation by osmolytic effect of hydroxyproline. Biopolymers 87 (5-6): 339-351.
-
(2007)
Biopolymers.
, vol.87
, Issue.5-6
, pp. 339-351
-
-
Kar, K.1
Kishore, N.2
-
195
-
-
35348925111
-
Effect of polyamines on the structure, thermal stability and 2,2,2-trifluoroethanol-induced aggregation of alpha-chymotrypsin
-
Rezaei-Ghaleh N, Ebrahim HA, Moosavi MAA, Nemat GM. 2007. Effect of polyamines on the structure, thermal stability and 2,2,2-trifluoroethanol-induced aggregation of alpha-chymotrypsin. Int J Biol Macromol 41 (5): 597-604.
-
(2007)
Int J Biol Macromol.
, vol.41
, Issue.5
, pp. 597-604
-
-
Rezaei-Ghaleh, N.1
Ebrahim, H.A.2
Moosavi, M.A.A.3
Nemat, G.M.4
-
196
-
-
1442289357
-
Expression, purification, and aggregation studies of His-tagged thermoalkalophilic lipase from Bacillus thermocatenulatus
-
Schlieben NH, Niefind K, Schomburg D. 2004. Expression, purification, and aggregation studies of His-tagged thermoalkalophilic lipase from Bacillus thermocatenulatus. Protein Expr Purif 34 (1): 103-110.
-
(2004)
Protein Expr Purif.
, vol.34
, Issue.1
, pp. 103-110
-
-
Schlieben, N.H.1
Niefind, K.2
Schomburg, D.3
-
197
-
-
33846159512
-
Stabilized antibody formulation
-
US6991790 B1
-
Lam XM, Oeswein JQ, Ongpipattanakul B, Shahrokh Z, Wang SX, Weissburg RP, Wong RL. 2000. Stabilized antibody formulation. US6991790 B1.
-
(2000)
-
-
Lam, X.M.1
Oeswein, J.Q.2
Ongpipattanakul, B.3
Shahrokh, Z.4
Wang, S.X.5
Weissburg, R.P.6
Wong, R.L.7
-
198
-
-
29144503698
-
Influence of osmolytes on inactivation and aggregation of muscle glycogen phosphorylase b by guanidine hydrochloride. Stimulation of protein aggregation under crowding conditions
-
Eronina TB, Chebotareva NA, Kurganov BI. 2005. Influence of osmolytes on inactivation and aggregation of muscle glycogen phosphorylase b by guanidine hydrochloride. Stimulation of protein aggregation under crowding conditions. Biochemistry (Mosc) 70 (9): 1020-1026.
-
(2005)
Biochemistry (Mosc)
, vol.70
, Issue.9
, pp. 1020-1026
-
-
Eronina, T.B.1
Chebotareva, N.A.2
Kurganov, B.I.3
-
199
-
-
36849059324
-
Dopamine differentially induces aggregation of A53T mutant and wild type alpha-synuclein: Insights into the protein chemistry of Parkinson's disease
-
Moussa CE, Mahmoodian F, Tomita Y, Sidhu A. 2008. Dopamine differentially induces aggregation of A53T mutant and wild type alpha-synuclein: Insights into the protein chemistry of Parkinson's disease. Biochem Biophys Res Commun 365 (4): 833-839.
-
(2008)
Biochem Biophys Res Commun.
, vol.365
, Issue.4
, pp. 833-839
-
-
Moussa, C.E.1
Mahmoodian, F.2
Tomita, Y.3
Sidhu, A.4
-
200
-
-
43249095250
-
The interaction of heparin/polyanions with bovine, porcine, and human growth hormone
-
Joshi SB, Kamerzell TJ, McNown C, Middaugh CR. 2008. The interaction of heparin/polyanions with bovine, porcine, and human growth hormone. J Pharm Sci 97 (4): 1368-1385.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.4
, pp. 1368-1385
-
-
Joshi, S.B.1
Kamerzell, T.J.2
McNown, C.3
Middaugh, C.R.4
-
201
-
-
0027769657
-
Densimetric determination of equilibrium binding of sucrose octasulfate with basic fibroblast growth factor
-
Arakawa T, Wen J, Philo JS. 1993. Densimetric determination of equilibrium binding of sucrose octasulfate with basic fibroblast growth factor. J Protein Chem 12 (6): 689-693.
-
(1993)
J Protein Chem.
, vol.12
, Issue.6
, pp. 689-693
-
-
Arakawa, T.1
Wen, J.2
Philo, J.S.3
-
202
-
-
33846596245
-
Influence of binding conjugated linoleic acid and myristic acid on the heat-and high-pressure-induced unfolding and aggregation of beta-lactoglobulin B
-
Considine T, Patel HA, Singh H, Creamer LK. 2007. Influence of binding conjugated linoleic acid and myristic acid on the heat-and high-pressure-induced unfolding and aggregation of beta-lactoglobulin B. Food Chem 102 (4): 1270-1280.
-
(2007)
Food Chem.
, vol.102
, Issue.4
, pp. 1270-1280
-
-
Considine, T.1
Patel, H.A.2
Singh, H.3
Creamer, L.K.4
-
203
-
-
4444301974
-
Rational design of solution additives for the prevention of protein aggregation
-
Baynes BM, Trout BL 2004. Rational design of solution additives for the prevention of protein aggregation. Biophys J 87 (3): 1631-1639.
-
(2004)
Biophys J.
, vol.87
, Issue.3
, pp. 1631-1639
-
-
Baynes, B.M.1
Trout B.L2
-
204
-
-
0028895083
-
A new strategy for enhancing the stability of lyophilized protein: The effect of the reconstitution medium on keratinocyte growth factor
-
Zhang MZ, Wen J, Arakawa T, Prestrelski SJ. 1995. A new strategy for enhancing the stability of lyophilized protein: The effect of the reconstitution medium on keratinocyte growth factor. Pharm Res 12 (10): 1447-1452.
-
(1995)
Pharm Res.
, vol.12
, Issue.10
, pp. 1447-1452
-
-
Zhang, M.Z.1
Wen, J.2
Arakawa, T.3
Prestrelski, S.J.4
-
205
-
-
0027828605
-
Formulation and stability of recombinant alpha 1-antitrypsin
-
Vemuri S, Yu CT, Roosdorp N. 1993. Formulation and stability of recombinant alpha 1-antitrypsin. Pharm Biotechnol 5: 263-286.
-
(1993)
Pharm Biotechnol.
, vol.5
, pp. 263-286
-
-
Vemuri, S.1
Yu, C.T.2
Roosdorp, N.3
-
206
-
-
0347594241
-
Relative influence of hydrophobicity and net charge in the aggregation of two homologous proteins
-
Calamai M, Taddei N, Stefani M, Ramponi G, Chiti F. 2003. Relative influence of hydrophobicity and net charge in the aggregation of two homologous proteins. Biochemistry (Mosc) 42 (51): 15078-15083.
-
(2003)
Biochemistry (Mosc).
, vol.42
, Issue.51
, pp. 15078-15083
-
-
Calamai, M.1
Taddei, N.2
Stefani, M.3
Ramponi, G.4
Chiti, F.5
-
207
-
-
0028357322
-
Stoichiometry of heparin binding to basic fibroblast growth factor
-
Arakawa T, Wen J, Philo JS. 1994. Stoichiometry of heparin binding to basic fibroblast growth factor. Arch Biochem Biophys 308 (1): 267-273.
-
(1994)
Arch Biochem Biophys.
, vol.308
, Issue.1
, pp. 267-273
-
-
Arakawa, T.1
Wen, J.2
Philo, J.S.3
-
208
-
-
0027313186
-
Physical stabilization of acidic fibroblast growth factor by polyanions
-
Volkin DB, Tsai PK, Dabora JM, Gress JO, Burke CJ, Linhardt RJ, Middaugh CR. 1993. Physical stabilization of acidic fibroblast growth factor by polyanions. Arch Biochem Biophys 300 (1): 30-41.
-
(1993)
Arch Biochem Biophys.
, vol.300
, Issue.1
, pp. 30-41
-
-
Volkin, D.B.1
Tsai, P.K.2
Dabora, J.M.3
Gress, J.O.4
Burke, C.J.5
Linhardt, R.J.6
Middaugh, C.R.7
-
209
-
-
0032486768
-
II. Electrostatic effect in the aggregation of heat-denatured RNase A and implications for protein additive design
-
Tsai AM, van Zanten JH, Betenbaugh MJ 1998. II. Electrostatic effect in the aggregation of heat-denatured RNase A and implications for protein additive design. Biotechnol Bioeng 59 (3): 281-285.
-
(1998)
Biotechnol Bioeng.
, vol.59
, Issue.3
, pp. 281-285
-
-
Tsai, A.M.1
Van Zanten, J.H.2
Betenbaugh M.J3
-
210
-
-
37349114505
-
Characterization of the aggregation-prevention activity of p97/valosin-containing protein
-
Song C, Wang Q, Li CC. 2007. Characterization of the aggregation-prevention activity of p97/valosin-containing protein. Biochemistry 46 (51): 14889-14898.
-
(2007)
Biochemistry.
, vol.46
, Issue.51
, pp. 14889-14898
-
-
Song, C.1
Wang, Q.2
Li, C.C.3
-
211
-
-
0029637153
-
Approaches for increasing the solution stability of proteins
-
Manning MC, Matsuura JE, Kendrick BS, Meyer JD, Dormish JJ, Vrkljian M, Ruth JR, Carpenter JF, Shefter E. 1995. Approaches for increasing the solution stability of proteins. Biotechnol Bioeng 48: 506-512.
-
(1995)
Biotechnol Bioeng.
, vol.48
, pp. 506-512
-
-
Manning, M.C.1
Matsuura, J.E.2
Kendrick, B.S.3
Meyer, J.D.4
Dormish, J.J.5
Vrkljian, M.6
Ruth, J.R.7
Carpenter, J.F.8
Shefter, E.9
-
212
-
-
33947197808
-
The influence of bovine serum albumin on beta-lactoglobulin denaturation, aggregation and gelation
-
Kehoe JJ, Morris ER, Brodkorb A. 2007. The influence of bovine serum albumin on beta-lactoglobulin denaturation, aggregation and gelation. Food Hydrocolloids 21 (56): 747-755.
-
(2007)
Food Hydrocolloids.
, vol.21
, Issue.56
, pp. 747-755
-
-
Kehoe, J.J.1
Morris, E.R.2
Brodkorb, A.3
-
213
-
-
33744800848
-
Cytosolic chaperonin protects folding intermediates of G ss from aggregation by recognizing hydrophobic ss-strands
-
Kubota S, Kubota H, Nagata K. 2006. Cytosolic chaperonin protects folding intermediates of G ss from aggregation by recognizing hydrophobic ss-strands. Proc Natl Acad Sci U S A 103 (22): 8360-8365.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, Issue.22
, pp. 8360-8365
-
-
Kubota, S.1
Kubota, H.2
Nagata, K.3
-
214
-
-
35748965834
-
Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin
-
Pivovarova AV, Chebotareva NA, Chernik IS, Gusev NB, Levitsky DI. 2007. Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin. FEBS J 274 (22): 5937-5948.
-
(2007)
FEBS J.
, vol.274
, Issue.22
, pp. 5937-5948
-
-
Pivovarova, A.V.1
Chebotareva, N.A.2
Chernik, I.S.3
Gusev, N.B.4
Levitsky, D.I.5
-
215
-
-
18844417388
-
Effects of small heat shock proteins on the thermal denaturation and aggregation of F-actin
-
Pivovarova AV, Mikhailova VV, Chernik IS, Chebotareva NA, Levitsky DI, Gusev NB. 2005. Effects of small heat shock proteins on the thermal denaturation and aggregation of F-actin. Biochem Biophys Res Commun 331 (4): 1548-1553.
-
(2005)
Biochem Biophys Res Commun.
, vol.331
, Issue.4
, pp. 1548-1553
-
-
Pivovarova, A.V.1
Mikhailova, V.V.2
Chernik, I.S.3
Chebotareva, N.A.4
Levitsky, D.I.5
Gusev, N.B.6
-
216
-
-
34547893834
-
Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase: Clues to a possible strategy for treating ALS
-
Yamashita H, Kawamata J, Okawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S. 2007. Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase: Clues to a possible strategy for treating ALS. J Neurochem 102 (5): 1497-1505.
-
(2007)
J Neurochem.
, vol.102
, Issue.5
, pp. 1497-1505
-
-
Yamashita, H.1
Kawamata, J.2
Okawa, K.3
Kanki, R.4
Nakamizo, T.5
Hatayama, T.6
Yamanaka, K.7
Takahashi, R.8
Shimohama, S.9
-
217
-
-
33745874108
-
Small heat shock proteins differentially affect A beta aggregation and toxicity
-
Lee S, Carson K, Rice FA, Good T. 2006. Small heat shock proteins differentially affect A beta aggregation and toxicity. Biochem Biophys Res Commun 347 (2): 527-533.
-
(2006)
Biochem Biophys Res Commun.
, vol.347
, Issue.2
, pp. 527-533
-
-
Lee, S.1
Carson, K.2
Rice, F.A.3
Good, T.4
-
218
-
-
39149124807
-
Glycation by ascorbic acid oxidation products leads to the aggregation of lens proteins
-
Linetsky M, Shipova E, Cheng R, Ortwerth BJ. 2008. Glycation by ascorbic acid oxidation products leads to the aggregation of lens proteins. Biochim Biophys Acta 1782 (1): 22-34.
-
(2008)
Biochim Biophys Acta.
, vol.1782
, Issue.1
, pp. 22-34
-
-
Linetsky, M.1
Shipova, E.2
Cheng, R.3
Ortwerth, B.J.4
-
219
-
-
33745758083
-
Inhibition of protein misfolding and aggregation by small rationally-designed peptides
-
Estrada LD, Soto C. 2006. Inhibition of protein misfolding and aggregation by small rationally-designed peptides. Curr Pharm Des 12 (20): 2557-2567.
-
(2006)
Curr Pharm Des.
, vol.12
, Issue.20
, pp. 2557-2567
-
-
Estrada, L.D.1
Soto, C.2
-
220
-
-
33645384655
-
Stoichiometric inhibition of amyloid beta-protein aggregation with peptides containing alternating alpha, alpha-disubstituted amino acids
-
Etienne MA, Aucoin JP, Fu Y, McCarley RL, Hammer RP. 2006. Stoichiometric inhibition of amyloid beta-protein aggregation with peptides containing alternating alpha, alpha-disubstituted amino acids. J Am Chem Soc 128 (11): 3522-3523.
-
(2006)
J Am Chem Soc.
, vol.128
, Issue.11
, pp. 3522-3523
-
-
Etienne, M.A.1
Aucoin, J.P.2
Fu, Y.3
McCarley, R.L.4
Hammer, R.P.5
-
221
-
-
33845900466
-
Control of aggregation in protein refolding: Cooperative effects of artificial chaperone and cold temperature
-
Yazdanparast R, Esmaeili MA, Khodagholi F. 2007. Control of aggregation in protein refolding: Cooperative effects of artificial chaperone and cold temperature. Int J Biol Macromol 40 (2): 126-133.
-
(2007)
Int J Biol Macromol.
, vol.40
, Issue.2
, pp. 126-133
-
-
Yazdanparast, R.1
Esmaeili, M.A.2
Khodagholi, F.3
-
222
-
-
0030980576
-
Varying effects of cyclodextrin derivatives on aggregation and thermal behavior of insulin in aqueous solution
-
Tokihiro K, Irie T, Uekama K. 1997. Varying effects of cyclodextrin derivatives on aggregation and thermal behavior of insulin in aqueous solution. Chem Pharm Bull (Tokyo) 45 (3): 525-531.
-
(1997)
Chem Pharm Bull (Tokyo).
, vol.45
, Issue.3
, pp. 525-531
-
-
Tokihiro, K.1
Irie, T.2
Uekama, K.3
-
223
-
-
36549040103
-
Dual effects of Tween 80 on protein stability
-
Wang W, Wang YJ, Wang DQ. 2008. Dual effects of Tween 80 on protein stability. Int J Pharm 347 (1-2): 31-38.
-
(2008)
Int J Pharm.
, vol.347
, Issue.1-2
, pp. 31-38
-
-
Wang, W.1
Wang, Y.J.2
Wang, D.Q.3
-
225
-
-
0028816796
-
Stability of protein formulations: Investigation of surfactant effects by a novel EPR spectroscopic technique
-
Bam NB, Randolph TW, Cleland JL. 1995. Stability of protein formulations: Investigation of surfactant effects by a novel EPR spectroscopic technique. Pharm Res 12 (1): 2-11.
-
(1995)
Pharm Res.
, vol.12
, Issue.1
, pp. 2-11
-
-
Bam, N.B.1
Randolph, T.W.2
Cleland, J.L.3
-
226
-
-
21344469442
-
Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation
-
Chou DK, Krishnamurthy R, Randolph TW, Carpenter JF, Manning MC. 2005. Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation. J Pharm Sci 94 (6): 1368-1381.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.6
, pp. 1368-1381
-
-
Chou, D.K.1
Krishnamurthy, R.2
Randolph, T.W.3
Carpenter, J.F.4
Manning, M.C.5
-
227
-
-
52449090177
-
Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: Structure and degradation pathways
-
Kerwin BA. 2008. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: Structure and degradation pathways. J Pharm Sci 97 (8): 2924-2935.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.8
, pp. 2924-2935
-
-
Kerwin, B.A.1
-
228
-
-
0031742802
-
Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions
-
Bam NB, Cleland JL, Yang J, Manning MC, Carpenter JF, Kelley RF, Randolph TW. 1998. Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions. J Pharm Sci 87 (12): 1554-1559.
-
(1998)
J Pharm Sci.
, vol.87
, Issue.12
, pp. 1554-1559
-
-
Bam, N.B.1
Cleland, J.L.2
Yang, J.3
Manning, M.C.4
Carpenter, J.F.5
Kelley, R.F.6
Randolph, T.W.7
-
229
-
-
0033822417
-
Protection of bovine serum albumin from aggregation by Tween 80
-
Arakawa T, Kita Y. 2000. Protection of bovine serum albumin from aggregation by Tween 80. J Pharm Sci 89 (5): 646-651.
-
(2000)
J Pharm Sci.
, vol.89
, Issue.5
, pp. 646-651
-
-
Arakawa, T.1
Kita, Y.2
-
230
-
-
0031391073
-
Use of poloxamer polymers to stabilize recombinant human growth hormone against various processing stresses
-
Katakam M, Banga AK. 1997. Use of poloxamer polymers to stabilize recombinant human growth hormone against various processing stresses. Pharm Dev Technol 2 (2): 143-149.
-
(1997)
Pharm Dev Technol.
, vol.2
, Issue.2
, pp. 143-149
-
-
Katakam, M.1
Banga, A.K.2
-
231
-
-
0030041098
-
Artificial chaperone-assisted refolding of carbonic anhydrase B
-
Rozema D, Gellman SH. 1996. Artificial chaperone-assisted refolding of carbonic anhydrase B. J Biol Chem 271 (7): 3478-3487.
-
(1996)
J Biol Chem.
, vol.271
, Issue.7
, pp. 3478-3487
-
-
Rozema, D.1
Gellman, S.H.2
-
232
-
-
0036111474
-
Inverse relationship of protein concentration and aggregation
-
Treuheit MJ, Kosky AA, Brems DN. 2002. Inverse relationship of protein concentration and aggregation. Pharm Res 19 (4): 511-516.
-
(2002)
Pharm Res.
, vol.19
, Issue.4
, pp. 511-516
-
-
Treuheit, M.J.1
Kosky, A.A.2
Brems, D.N.3
-
233
-
-
41249095351
-
Surfactant-induced amorphous aggregation of tobacco mosaic virus coat protein: A physical methods approach
-
Panyukov YV, Nemykh MA, Dobrov EN, Drachev VA. 2008. Surfactant-induced amorphous aggregation of tobacco mosaic virus coat protein: A physical methods approach. Macromol Biosci 8 (2): 199-209.
-
(2008)
Macromol Biosci.
, vol.8
, Issue.2
, pp. 199-209
-
-
Panyukov, Y.V.1
Nemykh, M.A.2
Dobrov, E.N.3
Drachev, V.A.4
-
234
-
-
30944448829
-
Low cetyltrimethylammonium bromide concentrations induce reversible amorphous aggregation of tobacco EXTERNAL FACTORS AFFECTING PROTEIN AGGREGATION 193 mosaic virus and its coat protein at room temperature
-
Panyukov YV, Nemykh MA, Rafikova ER, Kurganov BI, Yaguzhinsky LS, Arutyunyan AM, Drachev VA, Dobrov EN. 2006. Low cetyltrimethylammonium bromide concentrations induce reversible amorphous aggregation of tobacco EXTERNAL FACTORS AFFECTING PROTEIN AGGREGATION 193 mosaic virus and its coat protein at room temperature. Int J Biochem Cell Biol 38 (4): 533-543.
-
(2006)
Int J Biochem Cell Biol.
, vol.38
, Issue.4
, pp. 533-543
-
-
Panyukov, Y.V.1
Nemykh, M.A.2
Rafi Kova, E.R.3
Kurganov, B.I.4
Yaguzhinsky, L.S.5
Arutyunyan, A.M.6
Drachev, V.A.7
Dobrov, E.N.8
-
235
-
-
33646151145
-
A nondetergent sulfobetaine prevents protein aggregation in microcalorimetric studies
-
Collins T, D'Amico S, Georlette D, Marx JC, Huston AL, Feller G. 2006. A nondetergent sulfobetaine prevents protein aggregation in microcalorimetric studies. Anal Biochem 352 (2): 299-301.
-
(2006)
Anal Biochem.
, vol.352
, Issue.2
, pp. 299-301
-
-
Collins, T.1
D'Amico, S.2
Georlette, D.3
Marx, J.C.4
Huston, A.L.5
Feller, G.6
-
236
-
-
10644283956
-
Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution
-
Zhang Y, Roy S, Jones LS, Krishnan S, Kerwin BA, Chang BS, Manning MC, Randolph TW, Carpenter JF. 2004. Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution. J Pharm Sci 93 (12): 3076-3089.
-
(2004)
J Pharm Sci.
, vol.93
, Issue.12
, pp. 3076-3089
-
-
Zhang, Y.1
Roy, S.2
Jones, L.S.3
Krishnan, S.4
Kerwin, B.A.5
Chang, B.S.6
Manning, M.C.7
Randolph, T.W.8
Carpenter, J.F.9
-
237
-
-
14344261247
-
Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations
-
Roy S, Jung R, Kerwin BA, Randolph TW, Carpenter JF. 2005. Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations. J Pharm Sci 94 (2): 382-396.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.2
, pp. 382-396
-
-
Roy, S.1
Jung, R.2
Kerwin, B.A.3
Randolph, T.W.4
Carpenter, J.F.5
-
238
-
-
33947544337
-
Highly concentrated monoclonal antibody solutions: Direct analysis of physical structure and thermal stability
-
Harn N, Allan C, Oliver C, Middaugh CR. 2007. Highly concentrated monoclonal antibody solutions: Direct analysis of physical structure and thermal stability. J Pharm Sci 96 (3): 532-546.
-
(2007)
J Pharm Sci.
, vol.96
, Issue.3
, pp. 532-546
-
-
Harn, N.1
Allan, C.2
Oliver, C.3
Middaugh, C.R.4
-
239
-
-
33746099650
-
Protein aggregation in crowded environments
-
Ellis RJ, Minton AP. 2006. Protein aggregation in crowded environments. Biol Chem 387 (5): 485-497.
-
(2006)
Biol Chem.
, vol.387
, Issue.5
, pp. 485-497
-
-
Ellis, R.J.1
Minton, A.P.2
-
240
-
-
33646475011
-
Macromolecular crowding
-
Minton AP. 2006. Macromolecular crowding. Curr Biol 16(8): R269-R271.
-
(2006)
Curr Biol.
, vol.16
, Issue.8
-
-
Minton, A.P.1
-
241
-
-
33746045299
-
Stability of helix-rich proteins at high concentrations
-
Guo J, Harn N, Robbins A, Dougherty R, Middaugh CR. 2006. Stability of helix-rich proteins at high concentrations. Biochemistry 45 (28): 8686-8696.
-
(2006)
Biochemistry.
, vol.45
, Issue.28
, pp. 8686-8696
-
-
Guo, J.1
Harn, N.2
Robbins, A.3
Dougherty, R.4
Middaugh, C.R.5
-
242
-
-
34447566117
-
Quantitative characterization of weak self-association in concentrated solutions of immunoglobulin G via the measurement of sedimentation equilibrium and osmotic pressure
-
Jimenez M, Rivas G, Minton AP. 2007. Quantitative characterization of weak self-association in concentrated solutions of immunoglobulin G via the measurement of sedimentation equilibrium and osmotic pressure. Biochemistry (Mosc) 46 (28): 8373-8378.
-
(2007)
Biochemistry (Mosc).
, vol.46
, Issue.28
, pp. 8373-8378
-
-
Jimenez, M.1
Rivas, G.2
Minton, A.P.3
-
243
-
-
38449110484
-
Fluorescence-based soft-sensor for monitoring beta-lactoglobulin and alpha-lactalbumin solubility during thermal aggregation
-
Elshereef R, Budman H, Moresoli C, Legge RL. 2008. Fluorescence-based soft-sensor for monitoring beta-lactoglobulin and alpha-lactalbumin solubility during thermal aggregation. Biotechnol Bioeng 99 (3): 567-577.
-
(2008)
Biotechnol Bioeng.
, vol.99
, Issue.3
, pp. 567-577
-
-
Elshereef, R.1
Budman, H.2
Moresoli, C.3
Legge, R.L.4
-
244
-
-
3242670796
-
Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association
-
Sukumar M, Doyle BL, Combs JL, Pekar AH. 2004. Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association. Pharm Res 21 (7): 1087-1093.
-
(2004)
Pharm Res.
, vol.21
, Issue.7
, pp. 1087-1093
-
-
Sukumar, M.1
Doyle, B.L.2
Combs, J.L.3
Pekar, A.H.4
-
245
-
-
56749085339
-
Determination of protein aggregation with differential mobility analysis: application to IgG antibody
-
Pease LF III, Elliott JT, Tsai DH, Zachariah MR, Tarlov MJ. 2008. Determination of protein aggregation with differential mobility analysis: application to IgG antibody. Biotechnol Bioeng 101 (6): 1214-1222.
-
(2008)
Biotechnol Bioeng.
, vol.101
, Issue.6
, pp. 1214-1222
-
-
Pease L.F, I.I.I.1
Elliott, J.T.2
Tsai, D.H.3
Zachariah, M.R.4
Tarlov, M.J.5
-
246
-
-
27644462541
-
Aggregation kinetics of recombinant human FVIII (rFVIII)
-
Ramani K, Purohit V, Middaugh CR, Balasubramanian SV. 2005. Aggregation kinetics of recombinant human FVIII (rFVIII). J Pharm Sci 94 (9): 2023-2029.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.9
, pp. 2023-2029
-
-
Ramani, K.1
Purohit, V.2
Middaugh, C.R.3
Balasubramanian, S.V.4
-
247
-
-
0028567981
-
A model for the denaturation and aggregation of beta-lactoglobulin
-
Roefs SP, De Kruif KG. 1994. A model for the denaturation and aggregation of beta-lactoglobulin. Eur J Biochem 226 (3): 883-889.
-
(1994)
Eur J Biochem.
, vol.226
, Issue.3
, pp. 883-889
-
-
Roefs, S.P.1
De Kruif, K.G.2
-
248
-
-
0033520495
-
An NMR investigation of solution aggregation reactions preceding the misassembly of acid-denatured cold shock protein A into fibrils
-
Alexandrescu AT, Rathgeb-Szabo K. 1999. An NMR investigation of solution aggregation reactions preceding the misassembly of acid-denatured cold shock protein A into fibrils. J Mol Biol 291 (5): 1191-1206.
-
(1999)
J Mol Biol.
, vol.291
, Issue.5
, pp. 1191-1206
-
-
Alexandrescu, A.T.1
Rathgeb-Szabo, K.2
-
249
-
-
34548120750
-
Evidence for the formation of start aggregates as an initial stage of protein aggregation
-
Golub N, Meremyanin A, Markossian K, Eronina T, Chebotareva N, Asryants R, Muronets V, Kurganov B. 2007. Evidence for the formation of start aggregates as an initial stage of protein aggregation. FEBS Lett 581 (22): 4223-4227.
-
(2007)
FEBS Lett.
, vol.581
, Issue.22
, pp. 4223-4227
-
-
Golub, N.1
Meremyanin, A.2
Markossian, K.3
Eronina, T.4
Chebotareva, N.5
Asryants, R.6
Muronets, V.7
Kurganov, B.8
-
250
-
-
34250001656
-
Conditions limiting the influence of thiol-disulphide interchange reactions on the heat-induced aggregation kinetics of beta-lactoglobulin
-
Mounsey JS, O'Kennedy BT. 2007. Conditions limiting the influence of thiol-disulphide interchange reactions on the heat-induced aggregation kinetics of beta-lactoglobulin. Int Dairy J 17 (9): 1034-1042.
-
(2007)
Int Dairy J.
, vol.17
, Issue.9
, pp. 1034-1042
-
-
Mounsey, J.S.1
O'Kennedy, B.T.2
-
251
-
-
38349011533
-
Mechanisms of protein fibril formation: Nucleated polymerization with competing off-pathway aggregation
-
Powers ET, Powers DL. 2008. Mechanisms of protein fibril formation: Nucleated polymerization with competing off-pathway aggregation. Biophys J 94(2): 379-391.
-
(2008)
Biophys J.
, vol.94
, Issue.2
, pp. 379-391
-
-
Powers, E.T.1
Powers, D.L.2
-
252
-
-
23944504732
-
Thermal dissociation and unfolding of insulin
-
Huus K, Havelund S, Olsen HB, van de Weert M, Frokjaer S. 2005. Thermal dissociation and unfolding of insulin. Biochemistry (Mosc) 44 (33): 11171-11177.
-
(2005)
Biochemistry (Mosc).
, vol.44
, Issue.33
, pp. 11171-11177
-
-
Huus, K.1
Havelund, S.2
Olsen, H.B.3
Van de Weert, M.4
Frokjaer, S.5
-
253
-
-
0038362149
-
Coagulation factor VIII: Structure and stability
-
Wang W, Wang YJ, Kelner DN. 2003. Coagulation factor VIII: Structure and stability. Int J Pharm 259 (1-2): 1-15.
-
(2003)
Int J Pharm.
, vol.259
, Issue.1-2
, pp. 1-15
-
-
Wang, W.1
Wang, Y.J.2
Kelner, D.N.3
-
254
-
-
8644259054
-
Unfolding process of rusticyanin-Evidence of protein aggregation
-
Alcaraz LA, Donaire A. 2004. Unfolding process of rusticyanin-Evidence of protein aggregation. Eur J Biochem 271 (21): 4284-4292.
-
(2004)
Eur J Biochem.
, vol.271
, Issue.21
, pp. 4284-4292
-
-
Alcaraz, L.A.1
Donaire, A.2
-
255
-
-
3142774200
-
Effect of metal ions on de novo aggregation of full-length prion protein
-
Giese A, Levin J, Bertsch U, Kretzschmar H. 2004. Effect of metal ions on de novo aggregation of full-length prion protein. Biochem Biophys Res Commun 320 (4): 1240-1246.
-
(2004)
Biochem Biophys Res Commun.
, vol.320
, Issue.4
, pp. 1240-1246
-
-
Giese, A.1
Levin, J.2
Bertsch, U.3
Kretzschmar, H.4
-
256
-
-
4844230143
-
Effect of metal cations on the conformation and inactivation of recombinant human factor VIII
-
Derrick TS, Kashi RS, Durrani M, Jhingan A, Middaugh CR. 2004. Effect of metal cations on the conformation and inactivation of recombinant human factor VIII. J Pharm Sci 93 (10): 2549-2557.
-
(2004)
J Pharm Sci.
, vol.93
, Issue.10
, pp. 2549-2557
-
-
Derrick, T.S.1
Kashi, R.S.2
Durrani, M.3
Jhingan, A.4
Middaugh, C.R.5
-
257
-
-
28844476528
-
Calcium-induced changes to the molecular conformation and aggregate structure of beta-casein at the air-water interface
-
Vessely CR, Carpenter JF, Schwartz DK. 2005. Calcium-induced changes to the molecular conformation and aggregate structure of beta-casein at the air-water interface. Biomacromolecules 6 (6): 3334-3344.
-
(2005)
Biomacromolecules.
, vol.6
, Issue.6
, pp. 3334-3344
-
-
Vessely, C.R.1
Carpenter, J.F.2
Schwartz, D.K.3
-
258
-
-
2442628158
-
Investigation of the effects of copper ions on protein aggregation using a model system
-
Capanni C, Taddei N, Gabrielli S, Messori L, Orioli P, Chiti F, Stefania M, Ramponia G. 2004. Investigation of the effects of copper ions on protein aggregation using a model system. Cell Mol Life Sci 61 (7-8): 982-991.
-
(2004)
Cell Mol Life Sci.
, vol.61
, Issue.7-8
, pp. 982-991
-
-
Capanni, C.1
Taddei, N.2
Gabrielli, S.3
Messori, L.4
Orioli, P.5
Chiti, F.6
Stefania, M.7
Ramponia, G.8
-
259
-
-
33749331938
-
The effect of temperature and shear rate upon the aggregation of whey protein and its implications for milk fouling
-
Simmons MJH, Jayaraman P, Fryer PJ. 2007. The effect of temperature and shear rate upon the aggregation of whey protein and its implications for milk fouling. J Food Eng 79 (2): 517-528.
-
(2007)
J Food Eng.
, vol.79
, Issue.2
, pp. 517-528
-
-
Simmons, M.J.H.1
Jayaraman, P.2
Fryer, P.J.3
-
260
-
-
2642551384
-
Aggregation and denaturation of antibodies: A capillary electrophoresis, dynamic light scattering, and aqueous two-phase partitioning study
-
Bermudez O, Forciniti D. 2004. Aggregation and denaturation of antibodies: A capillary electrophoresis, dynamic light scattering, and aqueous two-phase partitioning study. J Chromatogr B 807 (1): 17-24.
-
(2004)
J Chromatogr B.
, vol.807
, Issue.1
, pp. 17-24
-
-
Bermudez, O.1
Forciniti, D.2
-
261
-
-
0029074530
-
Effect of surfactants on the physical stability of recombinant human growth hormone
-
Katakam M, Bell LN, Banga AK. 1995. Effect of surfactants on the physical stability of recombinant human growth hormone. J Pharm Sci 84 (6): 713-716.
-
(1995)
J Pharm Sci.
, vol.84
, Issue.6
, pp. 713-716
-
-
Katakam, M.1
Bell, L.N.2
Banga, A.K.3
-
262
-
-
41849084850
-
Moisture-induced aggregation of whey proteins in a protein/buffer model system
-
Zhou P, Liu X, Labuza TP. 2008. Moisture-induced aggregation of whey proteins in a protein/buffer model system. J Agric Food Chem 56 (6): 2048-2054.
-
(2008)
J Agric Food Chem.
, vol.56
, Issue.6
, pp. 2048-2054
-
-
Zhou, P.1
Liu, X.2
Labuza, T.P.3
-
263
-
-
25144498107
-
Thermal aggregation of SARS-CoV membrane protein
-
Lee YN, Chen LK, Ma HC, Yang HH, Li HP, Lo SY. 2005. Thermal aggregation of SARS-CoV membrane protein. J Virol Methods 129 (2): 152-161.
-
(2005)
J Virol Methods.
, vol.129
, Issue.2
, pp. 152-161
-
-
Lee, Y.N.1
Chen, L.K.2
Ma, H.C.3
Yang, H.H.4
Li, H.P.5
Lo, S.Y.6
-
264
-
-
0028326899
-
Simulations of kinetically irreversible protein aggregate structure
-
Patro SY, Przybycien TM. 1994. Simulations of kinetically irreversible protein aggregate structure. Biophys J 66: 1274-1289.
-
(1994)
Biophys J.
, vol.66
, pp. 1274-1289
-
-
Patro, S.Y.1
Przybycien, T.M.2
-
265
-
-
40849140680
-
Oligomerization of ribonuclease A under reducing conditions
-
Gotte G, Libonati M. 2008. Oligomerization of ribonuclease A under reducing conditions. Biochim Biophys Acta 1784 (4): 638-650.
-
(2008)
Biochim Biophys Acta.
, vol.1784
, Issue.4
, pp. 638-650
-
-
Gotte, G.1
Libonati, M.2
-
266
-
-
36849060218
-
Promotion of insulin aggregation by protein disulfide isomerase
-
Maeda R, Ado K, Takeda N, Taniguchi Y. 2007. Promotion of insulin aggregation by protein disulfide isomerase. Biochim Biophys Acta 1774 (12): 1619-1627.
-
(2007)
Biochim Biophys Acta.
, vol.1774
, Issue.12
, pp. 1619-1627
-
-
Maeda, R.1
Ado, K.2
Takeda, N.3
Taniguchi, Y.4
-
267
-
-
0034462997
-
Heat-induced aggregation of beta-lactoglobulin A and B with alpha-lactalbumin
-
Schokker EP, Singh H, Creamer LK. 2000. Heat-induced aggregation of beta-lactoglobulin A and B with alpha-lactalbumin. Int Dairy J 10 (12): 843-853.
-
(2000)
Int Dairy J.
, vol.10
, Issue.12
, pp. 843-853
-
-
Schokker, E.P.1
Singh, H.2
Creamer, L.K.3
-
268
-
-
34447291808
-
Binding of lysozyme to phospholipid bilayers: Evidence for protein aggregation upon membrane association
-
Gorbenko GP, Ioffe VM, Kinnunen PK. 2007. Binding of lysozyme to phospholipid bilayers: Evidence for protein aggregation upon membrane association. Biophys J 93 (1): 140-153.
-
(2007)
Biophys J.
, vol.93
, Issue.1
, pp. 140-153
-
-
Gorbenko, G.P.1
Ioffe, V.M.2
Kinnunen, P.K.3
-
269
-
-
34648819856
-
Enzyme-induced aggregation and gelation of proteins
-
Creusot N, Gruppen H. 2007. Enzyme-induced aggregation and gelation of proteins. Biotechnol Adv 25 (6): 597-601.
-
(2007)
Biotechnol Adv.
, vol.25
, Issue.6
, pp. 597-601
-
-
Creusot, N.1
Gruppen, H.2
-
270
-
-
4344669431
-
Protein structure, stability and solubility in water and other solvents
-
discussion 1234-1235
-
Pace CN, Trevino S, Prabhakaran E, Scholtz JM. 2004. Protein structure, stability and solubility in water and other solvents. Philos Trans R Soc Lond B Biol Sci 359 (1448): 1225-1234; discussion 1234-1235.
-
(2004)
Philos Trans R Soc Lond B Biol Sci.
, vol.359
, Issue.1448
, pp. 1225-1234
-
-
Pace, C.N.1
Trevino, S.2
Prabhakaran, E.3
Scholtz, J.M.4
-
271
-
-
41149180748
-
Effects of glycerol on the compaction and stability of the wild type and mutated rabbit muscle creatine kinase
-
Feng S, Yan YB. 2008. Effects of glycerol on the compaction and stability of the wild type and mutated rabbit muscle creatine kinase. Proteins 71 (2): 844-854.
-
(2008)
Proteins.
, vol.71
, Issue.2
, pp. 844-854
-
-
Feng, S.1
Yan, Y.B.2
-
272
-
-
45749153708
-
Structural changes and aggregation process of Cu/containing amine oxidase in the presence of 2,2,2 '-trifluoroethanol
-
Amani M, Yousefi R, Moosavi-Movahedi AA, Pintus F, Mura A, Floris G, Kurganov BI, Saboury AA. 2008. Structural changes and aggregation process of Cu/containing amine oxidase in the presence of 2,2,2 '-trifluoroethanol. Protein Pept Lett 15 (5): 521-527.
-
(2008)
Protein Pept Lett.
, vol.15
, Issue.5
, pp. 521-527
-
-
Amani, M.1
Yousefi, R.2
Moosavi-Movahedi, A.A.3
Pintus, F.4
Mura, A.5
Floris, G.6
Kurganov, B.I.7
Saboury, A.A.8
-
273
-
-
20044383430
-
Non-native intermediate conformational states of human growth hormone in the presence of organic solvents
-
Sukumar M, Storms SM, De Felippis MR. 2005. Non-native intermediate conformational states of human growth hormone in the presence of organic solvents. Pharm Res 22 (5): 789-796.
-
(2005)
Pharm Res.
, vol.22
, Issue.5
, pp. 789-796
-
-
Sukumar, M.1
Storms, S.M.2
De Felippis, M.R.3
-
274
-
-
0030453160
-
Degradation pathways, analytical characterization and formulation strategies of a peptide and a protein. Calcitonine and human growth hormone in comparison
-
Cholewinski M, Luckel B, Horn H. 1996. Degradation pathways, analytical characterization and formulation strategies of a peptide and a protein. Calcitonine and human growth hormone in comparison. Pharm Acta Helv 71 (6): 405-419.
-
(1996)
Pharm Acta Helv.
, vol.71
, Issue.6
, pp. 405-419
-
-
Cholewinski, M.1
Luckel, B.2
Horn, H.3
-
275
-
-
55749107596
-
Adsorption and function of recombinant factor VIII at solid-water interfaces in the presence of Tween-80
-
Joshi O, McGuire J, Wang DQ. 2008. Adsorption and function of recombinant factor VIII at solid-water interfaces in the presence of Tween-80. J Pharm Sci. doi:10.1002/jps.21333.
-
(2008)
J Pharm Sci
-
-
Joshi, O.1
McGuire, J.2
Wang, D.Q.3
-
276
-
-
33845900969
-
Protein aggregation and degradation during iodine labelling and its consequences for protein adsorption to biomaterials
-
Holmberg M, Stibius KB, Ndoni S, Larsen NB, Kingshott P, Hou XL. 2007. Protein aggregation and degradation during iodine labelling and its consequences for protein adsorption to biomaterials. Anal Biochem 361 (1): 120-125.
-
(2007)
Anal Biochem.
, vol.361
, Issue.1
, pp. 120-125
-
-
Holmberg, M.1
Stibius, K.B.2
Ndoni, S.3
Larsen, N.B.4
Kingshott, P.5
Hou, X.L.6
-
277
-
-
31944442534
-
Whey protein adsorption onto steel surfaces-Effect of temperature, flow rate, residence time and aggregation
-
Santos O, Nylander T, Paulsson M, Trägårdh C. 2006. Whey protein adsorption onto steel surfaces-Effect of temperature, flow rate, residence time and aggregation. J Food Eng 74 (4): 468-483.
-
(2006)
J Food Eng.
, vol.74
, Issue.4
, pp. 468-483
-
-
Santos, O.1
Nylander, T.2
Paulsson, M.3
Trägårdh, C.4
-
278
-
-
58849161897
-
Adsorption behavior of lysozyme and Tween 80 at hydrophilic and hydrophobic silica-water interfaces
-
Joshi O, McGuire J. 2008. Adsorption behavior of lysozyme and Tween 80 at hydrophilic and hydrophobic silica-water interfaces. Appl Biochem Biotechnol. doi:10.1007/s12010-008-8246-8.
-
(2008)
Appl Biochem Biotechnol
-
-
Joshi, O.1
McGuire, J.2
-
279
-
-
48549086114
-
Effects of solution conditions, processing parameters, and container materials on aggregation of a monoclonal antibody during freeze-thawing
-
Kueltzo LA, Wang W, Randolph TW, Carpenter JF. 2008. Effects of solution conditions, processing parameters, and container materials on aggregation of a monoclonal antibody during freeze-thawing. J Pharm Sci 97 (5): 1801-1812.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.5
, pp. 1801-1812
-
-
Kueltzo, L.A.1
Wang, W.2
Randolph, T.W.3
Carpenter, J.F.4
-
280
-
-
53549121957
-
Multivariate calibration of covalent aggregate fraction to the Raman spectrum of regular human insulin
-
Gryniewicz CM, Kauffman JF. 2008. Multivariate calibration of covalent aggregate fraction to the Raman spectrum of regular human insulin. J Pharm Sci 97 (9): 3727-3734.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.9
, pp. 3727-3734
-
-
Gryniewicz, C.M.1
Kauffman, J.F.2
-
281
-
-
17744363305
-
Silicone oil induced aggregation of proteins
-
Jones LS, Kaufmann A, Middaugh CR. 2005. Silicone oil induced aggregation of proteins. J Pharm Sci 94 (4): 918-927.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.4
, pp. 918-927
-
-
Jones, L.S.1
Kaufmann, A.2
Middaugh, C.R.3
-
282
-
-
34447622095
-
Solubility and aggregation of commercial alpha-lactalbumin at neutral pH
-
McGuffey MK, Otter DE, Zanten JHv, Foegeding EA. 2007. Solubility and aggregation of commercial alpha-lactalbumin at neutral pH. Int Dairy J 17 (10): 1168-1178.
-
(2007)
Int Dairy J.
, vol.17
, Issue.10
, pp. 1168-1178
-
-
McGuffey, M.K.1
Otter, D.E.2
Zanten, J.Hv.3
Foegeding, E.A.4
-
283
-
-
34250781639
-
Protect from light: Photodegradation and protein biologics
-
Kerwin BA, Remmele RL Jr. 2007. Protect from light: Photodegradation and protein biologics. J Pharm Sci 96 (6): 1468-1479.
-
(2007)
J Pharm Sci.
, vol.96
, Issue.6
, pp. 1468-1479
-
-
Kerwin, B.A.1
Remmele R.L, Jr.2
-
284
-
-
0025685391
-
Mechanisms of photochemically produced turbidity in lens protein solutions
-
Li DY, Borkman RF, Wang RH, Dillon J. 1990. Mechanisms of photochemically produced turbidity in lens protein solutions. Exp Eye Res 51 (6): 663-669.
-
(1990)
Exp Eye Res.
, vol.51
, Issue.6
, pp. 663-669
-
-
Li, D.Y.1
Borkman, R.F.2
Wang, R.H.3
Dillon, J.4
-
285
-
-
0036712109
-
Photoexcitation of tryptophan groups induces reduction of two disulfide bonds in goat alpha-lactalbumin
-
Vanhooren A, Devreese B, Vanhee K, Van Beeumen J, Hanssens I. 2002. Photoexcitation of tryptophan groups induces reduction of two disulfide bonds in goat alpha-lactalbumin. Biochemistry (Mosc) 41 (36): 11035-11043.
-
(2002)
Biochemistry (Mosc).
, vol.41
, Issue.36
, pp. 11035-11043
-
-
Vanhooren, A.1
Devreese, B.2
Vanhee, K.3
Van Beeumen, J.4
Hanssens, I.5
-
286
-
-
0037564169
-
Singlet oxygen-mediated damage to proteins and its consequences
-
Davies MJ. 2003. Singlet oxygen-mediated damage to proteins and its consequences. Biochem Biophys Res Commun 305 (3): 761-770.
-
(2003)
Biochem Biophys Res Commun.
, vol.305
, Issue.3
, pp. 761-770
-
-
Davies, M.J.1
-
287
-
-
0032832463
-
Isolating inclusion bodies from bacteria
-
Georgiou G, Valax P. 1999. Isolating inclusion bodies from bacteria. Methods Enzymol 309: 48-58.
-
(1999)
Methods Enzymol.
, vol.309
, pp. 48-58
-
-
Georgiou, G.1
Valax, P.2
-
288
-
-
33745991934
-
Protein activity in bacterial inclusion bodies correlates with predicted aggregation rates
-
de Groot NS, Ventura S. 2006. Protein activity in bacterial inclusion bodies correlates with predicted aggregation rates. J Biotechnol 125 (1): 110-113.
-
(2006)
J Biotechnol.
, vol.125
, Issue.1
, pp. 110-113
-
-
de Groot, N.S.1
Ventura, S.2
-
289
-
-
33847146241
-
The inhibition of aggregation of recombinant human consensus interferon-alpha mutant during Pichia pastoris fermentation
-
Hao Y, Chu J, Wang Y, Zhuang Y, Zhang S. 2007. The inhibition of aggregation of recombinant human consensus interferon-alpha mutant during Pichia pastoris fermentation. Appl Microbiol Biotechnol 74 (3): 578-584.
-
(2007)
Appl Microbiol Biotechnol.
, vol.74
, Issue.3
, pp. 578-584
-
-
Hao, Y.1
Chu, J.2
Wang, Y.3
Zhuang, Y.4
Zhang, S.5
-
290
-
-
53249107196
-
Inhibition of degradation and aggregation of recombinant human consensus interferon-alpha mutant expressed in Pichia pastoris with complex medium in bioreactor
-
Wu D, Hao YY, Chu J, Zhuang YP, Zhang SL. 2008. Inhibition of degradation and aggregation of recombinant human consensus interferon-alpha mutant expressed in Pichia pastoris with complex medium in bioreactor. Appl Microbiol Biotechnol. doi:10.1007/s00253-008-1629-5.
-
(2008)
Appl Microbiol Biotechnol
-
-
Wu, D.1
Hao, Y.Y.2
Chu, J.3
Zhuang, Y.P.4
Zhang, S.L.5
-
291
-
-
60549097554
-
Prevention of human G-CSF protein aggregation in recombinant Pichia pastoris fed-batch fermentation using additives
-
Bahrami A, Shojaosadati SA, Khalilzadeh R, Mohammadian J, Vashghani Farahani E, Masoumian MR. 2008. Prevention of human G-CSF protein aggregation in recombinant Pichia pastoris fed-batch fermentation using additives. Biotechnol Appl Biochem. doi:10.1042/BA20070267.
-
(2008)
Biotechnol Appl Biochem
-
-
Bahrami, A.1
Shojaosadati, S.A.2
Khalilzadeh, R.3
Mohammadian, J.4
Vashghani Farahani, E.5
Masoumian, M.R.6
-
292
-
-
16344374566
-
Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed
-
Chaderjian WB, Chin ET, Harris RJ, Etcheverry TM. 2005. Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed. Biotechnol Prog 21 (2): 550-553.
-
(2005)
Biotechnol Prog.
, vol.21
, Issue.2
, pp. 550-553
-
-
Chaderjian, W.B.1
Chin, E.T.2
Harris, R.J.3
Etcheverry, T.M.4
-
293
-
-
67449119292
-
Effects of glycosylation on the stability of protein pharmaceuticals
-
Sola RJ, Griebenow K. 2008. Effects of glycosylation on the stability of protein pharmaceuticals. J Pharm Sci. doi:10.1002/jps.21504.
-
(2008)
J Pharm Sci
-
-
Sola, R.J.1
Griebenow, K.2
-
294
-
-
33746904776
-
O-linked N-acetylglucosamine suppresses thermal aggregation of Sp1
-
Lim KH, Chang HI. 2006. O-linked N-acetylglucosamine suppresses thermal aggregation of Sp1. FEBS Lett 580 (19): 4645-4652.
-
(2006)
FEBS Lett.
, vol.580
, Issue.19
, pp. 4645-4652
-
-
Lim, K.H.1
Chang, H.I.2
-
295
-
-
38049046114
-
Modified expression of coagulation factor VIII by addition of a glycosylation site at the N terminus of the protein
-
Srour MA, Grupp J, Aburubaiha Z, Albert T, Brondke H, Oldenburg J, Schwaab R. 2008. Modified expression of coagulation factor VIII by addition of a glycosylation site at the N terminus of the protein. Ann Hematol 87 (2): 107-112.
-
(2008)
Ann Hematol.
, vol.87
, Issue.2
, pp. 107-112
-
-
Srour, M.A.1
Grupp, J.2
Aburubaiha, Z.3
Albert, T.4
Brondke, H.5
Oldenburg, J.6
Schwaab, R.7
-
296
-
-
45749100074
-
Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1
-
Singleton KD, Wischmeyer PE. 2008. Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1. JPEN J Parenter Enteral Nutr 32 (4): 371-376.
-
(2008)
JPEN J Parenter Enteral Nutr.
, vol.32
, Issue.4
, pp. 371-376
-
-
Singleton, K.D.1
Wischmeyer, P.E.2
-
297
-
-
0031916440
-
Enhanced glycosylation and sulfation of secretory proteoglycans is coupled to the expression of a basic secretory protein
-
Castle AM, Castle JD. 1998. Enhanced glycosylation and sulfation of secretory proteoglycans is coupled to the expression of a basic secretory protein. Mol Biol Cell 9 (3): 575-583.
-
(1998)
Mol Biol Cell.
, vol.9
, Issue.3
, pp. 575-583
-
-
Castle, A.M.1
Castle, J.D.2
-
298
-
-
0020744376
-
Glycosylation of thyroid-stimulating hormone in pituitary tumor cells: Influence of high mannose oligosaccharide units on subunit aggregation, combination, and intracellular degradation
-
Weintraub BD, Stannard BS, Meyers L. 1983. Glycosylation of thyroid-stimulating hormone in pituitary tumor cells: Influence of high mannose oligosaccharide units on subunit aggregation, combination, and intracellular degradation. Endocrinology 112 (4): 1331-1345.
-
(1983)
Endocrinology.
, vol.112
, Issue.4
, pp. 1331-1345
-
-
Weintraub, B.D.1
Stannard, B.S.2
Meyers, L.3
-
299
-
-
18144400877
-
Efficient refolding of aggregation-prone citrate synthase by polyol osmolytes: How well are protein folding and stability aspects coupled?
-
Mishra R, Seckler R, Bhat R. 2005. Efficient refolding of aggregation-prone citrate synthase by polyol osmolytes: How well are protein folding and stability aspects coupled? J Biol Chem 280 (16): 15553-15560.
-
(2005)
J Biol Chem.
, vol.280
, Issue.16
, pp. 15553-15560
-
-
Mishra, R.1
Seckler, R.2
Bhat, R.3
-
300
-
-
0032855077
-
Inhibition of aggregation side reactions during in vitro protein folding
-
De Bernardez Clark E, Schwarz E, Rudolph R. 1999. Inhibition of aggregation side reactions during in vitro protein folding. Methods Enzymol 309: 217-236.
-
(1999)
Methods Enzymol.
, vol.309
, pp. 217-236
-
-
De Bernardez Clark, E.1
Schwarz, E.2
Rudolph, R.3
-
301
-
-
0031950560
-
Refolding of recombinant proteins
-
Clark EDB. 1998. Refolding of recombinant proteins. Curr Opin Biotechnol 9 (2): 157-163.
-
(1998)
Curr Opin Biotechnol.
, vol.9
, Issue.2
, pp. 157-163
-
-
Clark, E.D.B.1
-
302
-
-
0028917406
-
Protein aggregation kinetics in an Escherichia coli strain overexpressing a Salmonella typhimurium CheY mutant gene
-
Klein J, Dhurjati P. 1995. Protein aggregation kinetics in an Escherichia coli strain overexpressing a Salmonella typhimurium CheY mutant gene. Appl Environ Microbiol 61 (4): 1220-1225.
-
(1995)
Appl Environ Microbiol.
, vol.61
, Issue.4
, pp. 1220-1225
-
-
Klein, J.1
Dhurjati, P.2
-
303
-
-
0028559525
-
Folding and aggregation of TEM beta-lactamase: Analogies with the formation of inclusion bodies in Escherichia coli
-
Georgiou G, Valax P, Ostermeier M, Horowitz PM. 1994. Folding and aggregation of TEM beta-lactamase: Analogies with the formation of inclusion bodies in Escherichia coli. Protein Sci 3 (11): 1953-1960.
-
(1994)
Protein Sci.
, vol.3
, Issue.11
, pp. 1953-1960
-
-
Georgiou, G.1
Valax, P.2
Ostermeier, M.3
Horowitz, P.M.4
-
305
-
-
0029916225
-
Control of aggregation in protein refolding: The temperature-leap tactic
-
Xie Y, Wetlaufer DB. 1996. Control of aggregation in protein refolding: The temperature-leap tactic. Protein Sci 5 (3): 517-523.
-
(1996)
Protein Sci.
, vol.5
, Issue.3
, pp. 517-523
-
-
Xie, Y.1
Wetlaufer, D.B.2
-
307
-
-
0031696773
-
Effect of denaturant and protein concentrations upon protein refolding and aggregation: A simple lattice model
-
Gupta P, Hall CK, Voegler AC. 1998. Effect of denaturant and protein concentrations upon protein refolding and aggregation: A simple lattice model. Protein Sci 7 (12): 2642-2652.
-
(1998)
Protein Sci.
, vol.7
, Issue.12
, pp. 2642-2652
-
-
Gupta, P.1
Hall, C.K.2
Voegler, A.C.3
-
308
-
-
0029001489
-
Comparing the refolding and reoxidation of recombinant porcine growth hormone from a urea denatured state and from Escherichia coli inclusion bodies
-
Cardamone M, Puri NK, Brandon MR. 1995. Comparing the refolding and reoxidation of recombinant porcine growth hormone from a urea denatured state and from Escherichia coli inclusion bodies. Biochemistry 34 (17): 5773-5794.
-
(1995)
Biochemistry.
, vol.34
, Issue.17
, pp. 5773-5794
-
-
Cardamone, M.1
Puri, N.K.2
Brandon, M.R.3
-
309
-
-
0030582355
-
Folding pathway of human alpha 1-antitrypsin: Characterization of an intermediate that is active but prone to aggregation
-
Kim D, Yu MH. 1996. Folding pathway of human alpha 1-antitrypsin: Characterization of an intermediate that is active but prone to aggregation. Biochem Biophys Res Commun 226 (2): 378-384.
-
(1996)
Biochem Biophys Res Commun.
, vol.226
, Issue.2
, pp. 378-384
-
-
Kim, D.1
Yu, M.H.2
-
311
-
-
0032127796
-
Effect of additives on refolding of a denatured protein
-
Yasuda M, Murakami Y, Sowa A, Ogino H, Ishikawa H. 1998. Effect of additives on refolding of a denatured protein. Biotechnol Prog 14 (4): 601-606.
-
(1998)
Biotechnol Prog.
, vol.14
, Issue.4
, pp. 601-606
-
-
Yasuda, M.1
Murakami, Y.2
Sowa, A.3
Ogino, H.4
Ishikawa, H.5
-
312
-
-
0029944619
-
Effective renaturation of denatured and reduced immunoglobulin G in vitro without assistance of chaperone
-
Maeda Y, Ueda T, Imoto T. 1996. Effective renaturation of denatured and reduced immunoglobulin G in vitro without assistance of chaperone. Protein Eng 9: 95-100.
-
(1996)
Protein Eng.
, vol.9
, pp. 95-100
-
-
Maeda, Y.1
Ueda, T.2
Imoto, T.3
-
313
-
-
0026656965
-
Polyethylene glycol enhanced protein refolding
-
Cleland JL, Builder SE, Swartz JR, Winkler M, Chang JY, Wang DI. 1992. Polyethylene glycol enhanced protein refolding. Biotechnology (N Y) 10 (9): 1013-1019.
-
(1992)
Biotechnology (N Y).
, vol.10
, Issue.9
, pp. 1013-1019
-
-
Cleland, J.L.1
Builder, S.E.2
Swartz, J.R.3
Winkler, M.4
Chang, J.Y.5
Wang, D.I.6
-
314
-
-
0029146296
-
Control of aggregation in protein refolding: A variety of surfactants promote renaturation of carbonic anhydrase II
-
Wetlaufer DB, Xie Y. 1995. Control of aggregation in protein refolding: A variety of surfactants promote renaturation of carbonic anhydrase II. Protein Sci 4 (8): 1535-1543.
-
(1995)
Protein Sci.
, vol.4
, Issue.8
, pp. 1535-1543
-
-
Wetlaufer, D.B.1
Xie, Y.2
-
315
-
-
36348979413
-
Effect of high concentration of inert cosolutes on the refolding of an enzyme: Carbonic anhydrase B in sucrose and Ficoll 70
-
Monterroso B, Minton AP. 2007. Effect of high concentration of inert cosolutes on the refolding of an enzyme: Carbonic anhydrase B in sucrose and Ficoll 70. J Biol Chem 282 (46): 33452-33458.
-
(2007)
J Biol Chem.
, vol.282
, Issue.46
, pp. 33452-33458
-
-
Monterroso, B.1
Minton, A.P.2
-
316
-
-
0033572725
-
Effects of macromolecular crowding on protein folding and aggregation
-
van den Berg B, Ellis RJ, Dobson CM. 1999. Effects of macromolecular crowding on protein folding and aggregation. EMBO J 18 (24): 6927-6933.
-
(1999)
EMBO J.
, vol.18
, Issue.24
, pp. 6927-6933
-
-
Van Den Berg, B.1
Ellis, R.J.2
Dobson, C.M.3
-
317
-
-
1842410676
-
Oxidative renaturation of lysozyme at high concentrations
-
Hevehan D, De Bernardez-Clark E. 1997. Oxidative renaturation of lysozyme at high concentrations. Biotechnol Bioeng 54: 221-230.
-
(1997)
Biotechnol Bioeng.
, vol.54
, pp. 221-230
-
-
Hevehan, D.1
De Bernardez-Clark, E.2
-
319
-
-
34249063646
-
L-argininamide improves the refolding more effectively than L-arginine
-
Hamada H, Shiraki K. 2007. L-argininamide improves the refolding more effectively than L-arginine. J Biotechnol 130 (2): 153-160.
-
(2007)
J Biotechnol.
, vol.130
, Issue.2
, pp. 153-160
-
-
Hamada, H.1
Shiraki, K.2
-
320
-
-
0032545150
-
Global analysis of the effects of temperature and denaturant on the folding and unfolding kinetics of the N-terminal domain of the protein L9
-
Kuhlman B, Luisi DL, Evans PA, Raleigh DP. 1998. Global analysis of the effects of temperature and denaturant on the folding and unfolding kinetics of the N-terminal domain of the protein L9. J Mol Biol 284 (5): 1661-1670.
-
(1998)
J Mol Biol.
, vol.284
, Issue.5
, pp. 1661-1670
-
-
Kuhlman, B.1
Luisi, D.L.2
Evans, P.A.3
Raleigh, D.P.4
-
321
-
-
0030984109
-
Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability
-
Scalley ML, Baker D. 1997. Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability. Proc Natl Acad Sci U S A 94 (20): 10636-10640.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, Issue.20
, pp. 10636-10640
-
-
Scalley, M.L.1
Baker, D.2
-
323
-
-
0031155312
-
Refolding with a piece of the ring
-
King J. 1997. Refolding with a piece of the ring. Nat Biotechnol 15 (6): 514-515.
-
(1997)
Nat Biotechnol.
, vol.15
, Issue.6
, pp. 514-515
-
-
King, J.1
-
324
-
-
0032548994
-
Thermodynamic stability and folding of GroEL minichaperones
-
Golbik R, Zahn R, Harding SE, Fersht AR. 1998. Thermodynamic stability and folding of GroEL minichaperones. J Mol Biol 276 (2): 505-515.
-
(1998)
J Mol Biol.
, vol.276
, Issue.2
, pp. 505-515
-
-
Golbik, R.1
Zahn, R.2
Harding, S.E.3
Fersht, A.R.4
-
325
-
-
0031157025
-
Molecular chaperones, folding catalysts, and the recovery of active recombinant proteins from E
-
Thomas JG, Ayling A, Baneyx F. 1997. Molecular chaperones, folding catalysts, and the recovery of active recombinant proteins from E. coli. To fold or to refold. Appl Biochem Biotechnol 66 (3): 197-238.
-
(1997)
coli. To fold or to refold. Appl Biochem Biotechnol.
, vol.66
, Issue.3
, pp. 197-238
-
-
Thomas, J.G.1
Ayling, A.2
Baneyx, F.3
-
326
-
-
0029774156
-
Artificial chaperone-assisted refolding of denatured-reduced lysozyme: Modulation of the competition between renaturation and aggregation
-
Rozema D, Gellman SH. 1996. Artificial chaperone-assisted refolding of denatured-reduced lysozyme: Modulation of the competition between renaturation and aggregation. Biochemistry 35 (49): 15760-15771.
-
(1996)
Biochemistry.
, vol.35
, Issue.49
, pp. 15760-15771
-
-
Rozema, D.1
Gellman, S.H.2
-
327
-
-
0030804221
-
Pathway of detergent-mediated and peptide ligand-mediated refolding of heterodimeric class II major histocompatibility complex (MHC) molecules
-
Stockel J, Doring K, Malotka J, Jahnig F, Dornmair K. 1997. Pathway of detergent-mediated and peptide ligand-mediated refolding of heterodimeric class II major histocompatibility complex (MHC) molecules. Eur J Biochem 248 (3): 684-691.
-
(1997)
Eur J Biochem.
, vol.248
, Issue.3
, pp. 684-691
-
-
Stockel, J.1
Doring, K.2
Malotka, J.3
Jahnig, F.4
Dornmair, K.5
-
328
-
-
42049114013
-
Successful control of aggregation and folding rates during refolding of denatured lysozyme by adding N-methylimidazolium cations with various N '-substituents
-
Yamaguchi S, Yamamoto E, Tsukiji S, Nagamune T. 2008. Successful control of aggregation and folding rates during refolding of denatured lysozyme by adding N-methylimidazolium cations with various N '-substituents. Biotechnol Prog 24 (2): 402-408.
-
(2008)
Biotechnol Prog.
, vol.24
, Issue.2
, pp. 402-408
-
-
Yamaguchi, S.1
Yamamoto, E.2
Tsukiji, S.3
Nagamune, T.4
-
329
-
-
0029980026
-
Effect of additives on the renaturation of reduced lysozyme in the presence of 4 m urea
-
Maeda Y, Yamada H, Ueda T, Imoto T. 1996. Effect of additives on the renaturation of reduced lysozyme in the presence of 4 m urea. Protein Eng 9: 461-465.
-
(1996)
Protein Eng.
, vol.9
, pp. 461-465
-
-
Maeda, Y.1
Yamada, H.2
Ueda, T.3
Imoto, T.4
-
330
-
-
0037466513
-
The effects of arginine on refolding of aggregated proteins: Not facilitate refolding, but suppress aggregation
-
Arakawa T, Tsumoto K. 2003. The effects of arginine on refolding of aggregated proteins: Not facilitate refolding, but suppress aggregation. Biochem Biophys Res Commun 304 (1): 148-152.
-
(2003)
Biochem Biophys Res Commun.
, vol.304
, Issue.1
, pp. 148-152
-
-
Arakawa, T.1
Tsumoto, K.2
-
331
-
-
0344495223
-
Solubilization of active green fluorescent protein from insoluble particles by guanidine and arginine
-
Tsumoto K, Umetsu M, Kumagai I, Ejima D, Arakawa T. 2003. Solubilization of active green fluorescent protein from insoluble particles by guanidine and arginine. Biochem Biophys Res Commun 312 (4): 1383-1386.
-
(2003)
Biochem Biophys Res Commun.
, vol.312
, Issue.4
, pp. 1383-1386
-
-
Tsumoto, K.1
Umetsu, M.2
Kumagai, I.3
Ejima, D.4
Arakawa, T.5
-
332
-
-
0034759325
-
Manufacture and quality control of CAMPATH-1 antibodies for clinical trials
-
Phillips J, Drumm A, Harrison P, Bird P, Bhamra K, Berrie E, Hale G. 2001. Manufacture and quality control of CAMPATH-1 antibodies for clinical trials. Cytotherapy 3 (3): 233-242.
-
(2001)
Cytotherapy.
, vol.3
, Issue.3
, pp. 233-242
-
-
Phillips, J.1
Drumm, A.2
Harrison, P.3
Bird, P.4
Bhamra, K.5
Berrie, E.6
Hale, G.7
-
333
-
-
38149128094
-
Protein isolated from biopharmaceutical formulations cannot be used for comparative studies: Follow-up to "a case study using Epoetin Alfa from Epogen and EPREX"
-
Heavner GA, Arakawa T, Philo JS, Calmann MA, Labrenz S. 2007. Protein isolated from biopharmaceutical formulations cannot be used for comparative studies: Follow-up to "a case study using Epoetin Alfa from Epogen and EPREX." J Pharm Sci 96 (12): 3214-3225.
-
(2007)
J Pharm Sci.
, vol.96
, Issue.12
, pp. 3214-3225
-
-
Heavner, G.A.1
Arakawa, T.2
Philo, J.S.3
Calmann, M.A.4
Labrenz, S.5
-
335
-
-
0030443567
-
Surface-induced denaturation of proteins during freezing and its inhibition by surfactants
-
Chang BS, Kendrick BS, Carpenter JF. 1996. Surface-induced denaturation of proteins during freezing and its inhibition by surfactants. J Pharm Sci 85 (12): 1325-1330.
-
(1996)
J Pharm Sci.
, vol.85
, Issue.12
, pp. 1325-1330
-
-
Chang, B.S.1
Kendrick, B.S.2
Carpenter, J.F.3
-
336
-
-
33846125282
-
Stabilized monomeric protein compositions
-
US5656730, Enzon, Inc
-
Lee LS. 1997. Stabilized monomeric protein compositions. US5656730, Enzon, Inc.
-
(1997)
-
-
Lee, L.S.1
-
337
-
-
0034255393
-
Lyophilization and development of solid protein pharmaceuticals
-
Wang W. 2000. Lyophilization and development of solid protein pharmaceuticals. Int J Pharm 203 (1-2): 1-60.
-
(2000)
Int J Pharm.
, vol.203
, Issue.1-2
, pp. 1-60
-
-
Wang, W.1
-
338
-
-
33747449180
-
Influence of controoled nucleation by ultrasounds on ice morphology of froaen formulations for pharmaceutical proteins freeze-drying
-
Nakagawa K, Hottot A, Vessot S, Andrieu J. 2006. Influence of controoled nucleation by ultrasounds on ice morphology of froaen formulations for pharmaceutical proteins freeze-drying. Chem Eng Proc 45: 783-791.
-
(2006)
Chem Eng Proc.
, vol.45
, pp. 783-791
-
-
Nakagawa, K.1
Hottot, A.2
Vessot, S.3
Andrieu, J.4
-
339
-
-
0025952279
-
Effect of freezing on aggregation of human growth hormone
-
Eckhardt BM, Oeswein JQ, Bewley TA. 1991. Effect of freezing on aggregation of human growth hormone. Pharm Res 8 (11): 1360-1364.
-
(1991)
Pharm Res.
, vol.8
, Issue.11
, pp. 1360-1364
-
-
Eckhardt, B.M.1
Oeswein, J.Q.2
Bewley, T.A.3
-
340
-
-
0030586740
-
Polymers protect lactate dehydrogenase during freeze-drying by inhibiting dissociation in the frozen state
-
Anchordoquy TJ, Carpenter JF. 1996. Polymers protect lactate dehydrogenase during freeze-drying by inhibiting dissociation in the frozen state. Arch Biochem Biophys 332 (2): 231-238.
-
(1996)
Arch Biochem Biophys.
, vol.332
, Issue.2
, pp. 231-238
-
-
Anchordoquy, T.J.1
Carpenter, J.F.2
-
341
-
-
0027272126
-
Freeze-thaw studies of a model protein, lactate dehydrogenase, in the presence of cryoprotectants
-
Nema S, Avis KE. 1992. Freeze-thaw studies of a model protein, lactate dehydrogenase, in the presence of cryoprotectants. J Parenter Sci Technol 47: 76-83.
-
(1992)
J Parenter Sci Technol.
, vol.47
, pp. 76-83
-
-
Nema, S.1
Avis, K.E.2
-
343
-
-
0030932504
-
Destabilization of human serum albumin by polyethylene glycols studied by thermodynamical equilibrium and kinetic approaches
-
Farruggia B, Garcia G, D'Angelo C, Pico G. 1997. Destabilization of human serum albumin by polyethylene glycols studied by thermodynamical equilibrium and kinetic approaches. Int J Biol Macromol 20 (1): 43-51.
-
(1997)
Int J Biol Macromol.
, vol.20
, Issue.1
, pp. 43-51
-
-
Farruggia, B.1
Garcia, G.2
D'Angelo, C.3
Pico, G.4
-
344
-
-
33846125282
-
Stabilized monomeric protein compositions
-
US 5656730
-
Lee LS. 1997. Stabilized monomeric protein compositions. US 5656730.
-
(1997)
-
-
Lee, L.S.1
-
345
-
-
0031976660
-
The formulation of recombinant factor IX: Stability, robustness, and convenience
-
Bush L, Webb C, Bartlett L, Burnett B. 1998. The formulation of recombinant factor IX: Stability, robustness, and convenience. Semin Hematol 35 (2 Suppl. 2): 18-21.
-
(1998)
Semin Hematol.
, vol.35
, Issue.2 SUPPL. 2
, pp. 18-21
-
-
Bush, L.1
Webb, C.2
Bartlett, L.3
Burnett, B.4
-
346
-
-
0031773791
-
Effect of Tween 20 on freeze-thawing-and agitation-induced aggregation of recombinant human factor XIII
-
Kreilgaard L, Jones LS, Randolph TW, Frokjaer S, Flink JM, Manning MC, Carpenter JF. 1998. Effect of Tween 20 on freeze-thawing-and agitation-induced aggregation of recombinant human factor XIII. J Pharm Sci 87 (12): 1597-1603.
-
(1998)
J Pharm Sci.
, vol.87
, Issue.12
, pp. 1597-1603
-
-
Kreilgaard, L.1
Jones, L.S.2
Randolph, T.W.3
Frokjaer, S.4
Flink, J.M.5
Manning, M.C.6
Carpenter, J.F.7
-
347
-
-
0002643399
-
Minimizing protein inactivation
-
In Creighton TE, ed., Protein Function a Practical Approach. Oxford, England: Information Press
-
Volkin DB, Klibanov AM. 1989. Minimizing protein inactivation. In Creighton TE, ed., Protein Function a Practical Approach. Oxford, England: Information Press, pp. 1-24.
-
(1989)
, pp. 1-24
-
-
Volkin, D.B.1
Klibanov, A.M.2
-
349
-
-
0025892154
-
The use of surface tension measurements in the design of antibody-based product formulations
-
Levine HL, Ransohoff TC, Kawahata RT, McGregor WC. 1991. The use of surface tension measurements in the design of antibody-based product formulations. J Parenter Sci Technol 45 (3): 160-165.
-
(1991)
J Parenter Sci Technol.
, vol.45
, Issue.3
, pp. 160-165
-
-
Levine, H.L.1
Ransohoff, T.C.2
Kawahata, R.T.3
McGregor, W.C.4
-
350
-
-
84886079085
-
Formulation Strategies for Protein Therapeutics
-
Boston: IBC Life Sciences
-
Kueltzo LA. 2004. Formulation Strategies for Protein Therapeutics. Boston: IBC Life Sciences.
-
(2004)
-
-
Kueltzo, L.A.1
-
351
-
-
35348827271
-
Determining antibody stability: Creation of solid-liquid interfacial effects within a high shear environment
-
Biddlecombe JG, Craig AV, Zhang H, Uddin S, Mulot S, Fish BC, Bracewell DG. 2007. Determining antibody stability: Creation of solid-liquid interfacial effects within a high shear environment. Biotechnol Prog 23 (5): 1218-1222.
-
(2007)
Biotechnol Prog.
, vol.23
, Issue.5
, pp. 1218-1222
-
-
Biddlecombe, J.G.1
Craig, A.V.2
Zhang, H.3
Uddin, S.4
Mulot, S.5
Fish, B.C.6
Bracewell, D.G.7
-
352
-
-
0035663205
-
In situ study of insulin aggregation induced by water-organic solvent interface
-
Kwon YM, Baudys M, Knutson K, Kim SW. 2001. In situ study of insulin aggregation induced by water-organic solvent interface. Pharm Res 18 (12): 1754-1759.
-
(2001)
Pharm Res.
, vol.18
, Issue.12
, pp. 1754-1759
-
-
Kwon, Y.M.1
Baudys, M.2
Knutson, K.3
Kim, S.W.4
-
353
-
-
0032957319
-
Acute and long-term stability studies of deoxy hemoglobin and characterization of ascorbate-induced modifications
-
Kerwin BA, Akers MJ, Apostol I, Moore-Einsel C, Etter JE, Hess E, Lippincott J, Levine J, Mathews AJ, Revilla-Sharp P, Schubert R, Looker DL. 1999. Acute and long-term stability studies of deoxy hemoglobin and characterization of ascorbate-induced modifications. J Pharm Sci 88 (1): 79-88.
-
(1999)
J Pharm Sci.
, vol.88
, Issue.1
, pp. 79-88
-
-
Kerwin, B.A.1
Akers, M.J.2
Apostol, I.3
Moore-Einsel, C.4
Etter, J.E.5
Hess, E.6
Lippincott, J.7
Levine, J.8
Mathews, A.J.9
Revilla-Sharp, P.10
Schubert, R.11
Looker, D.L.12
-
354
-
-
40749088430
-
Effect of dynamic high pressure on whey protein aggregation: a 200 AGGREGATION OF THERAPEUTIC PROTEINS comparison with the effect of continuous short-time thermal treatments
-
Grácia-JuliáA, RenéM, Cortés MM, Picart L, López PT, Chevalier D, Dumay E. 2008. Effect of dynamic high pressure on whey protein aggregation: a 200 AGGREGATION OF THERAPEUTIC PROTEINS comparison with the effect of continuous short-time thermal treatments. Food Hydrocolloids 22 (6): 1014-1032.
-
(2008)
Food Hydrocolloids.
, vol.22
, Issue.6
, pp. 1014-1032
-
-
Grácia-Juliá, A.1
René, M.2
Cortés, M.M.3
Picart, L.4
López, P.T.5
Chevalier, D.6
Dumay, E.7
-
355
-
-
28944443945
-
Pressure-induced unfolding and aggregation of the proteins in whey protein concentrate solutions
-
Patel HA, Singh H, Havea P, Considine T, Creamer LK. 2005. Pressure-induced unfolding and aggregation of the proteins in whey protein concentrate solutions. J Agric Food Chem 53 (24): 9590-9601.
-
(2005)
J Agric Food Chem.
, vol.53
, Issue.24
, pp. 9590-9601
-
-
Patel, H.A.1
Singh, H.2
Havea, P.3
Considine, T.4
Creamer, L.K.5
-
356
-
-
24344491042
-
High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: Thermodynamics, kinetics, and application to accelerated formulation studies
-
Seefeldt MB, Kim YS, Tolley KP, Seely J, Carpenter JF, Randolph TW. 2005. High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: Thermodynamics, kinetics, and application to accelerated formulation studies. Protein Sci 14 (9): 2258-2266.
-
(2005)
Protein Sci.
, vol.14
, Issue.9
, pp. 2258-2266
-
-
Seefeldt, M.B.1
Kim, Y.S.2
Tolley, K.P.3
Seely, J.4
Carpenter, J.F.5
Randolph, T.W.6
-
357
-
-
33645975504
-
High pressure-induced changes in bovine milk proteins: a review
-
Huppertz T, Fox PF, de Kruif KG, Kelly AL. 2006. High pressure-induced changes in bovine milk proteins: a review. Biochim Biophys Acta 1764 (3): 593-598.
-
(2006)
Biochim Biophys Acta.
, vol.1764
, Issue.3
, pp. 593-598
-
-
Huppertz, T.1
Fox, P.F.2
De Kruif, K.G.3
Kelly, A.L.4
-
358
-
-
0034999046
-
Effects of high pressure and low temperature on beta-lactoglobulin unfolding and aggregation
-
Kolakowski P, Dumay E, Cheftel JC. 2001. Effects of high pressure and low temperature on beta-lactoglobulin unfolding and aggregation. Food Hydrocolloids 15 (3): 215-232.
-
(2001)
Food Hydrocolloids.
, vol.15
, Issue.3
, pp. 215-232
-
-
Kolakowski, P.1
Dumay, E.2
Cheftel, J.C.3
-
359
-
-
0035861633
-
High pressure refolding of recombinant human growth hormone from insoluble aggregates. Structural transformations, kinetic barriers, and energetics
-
St John RJ, Carpenter JF, Balny C, Randolph TW. 2001. High pressure refolding of recombinant human growth hormone from insoluble aggregates. Structural transformations, kinetic barriers, and energetics. J Biol Chem 276 (50): 46856-46863.
-
(2001)
J Biol. Chem.
, vol.276
, Issue.50
, pp. 46856-46863
-
-
St John, R.J.1
Carpenter, J.F.2
Balny, C.3
Randolph, T.W.4
-
360
-
-
0033539596
-
High pressure fosters protein refolding from aggregates at high concentrations
-
St John RJ, Carpenter JF, Randolph TW. 1999. High pressure fosters protein refolding from aggregates at high concentrations. Proc Natl Acad Sci U S A 96 (23): 13029-13033.
-
(1999)
Proc Natl Acad Sci U S A.
, vol.96
, Issue.23
, pp. 13029-13033
-
-
St John, R.J.1
Carpenter, J.F.2
Randolph, T.W.3
-
361
-
-
0035988066
-
High-pressure refolding of disulfide-cross-linked lysozyme aggregates: Thermodynamics and optimization
-
St John RJ, Carpenter JF, Randolph TW. 2002. High-pressure refolding of disulfide-cross-linked lysozyme aggregates: Thermodynamics and optimization. Biotechnol Prog 18 (3): 565-571.
-
(2002)
Biotechnol Prog.
, vol.18
, Issue.3
, pp. 565-571
-
-
St John, R.J.1
Carpenter, J.F.2
Randolph, T.W.3
-
362
-
-
0031214378
-
An exceptionally stable helix from the ribosomal protein L9: Implications for protein folding and stability
-
Kuhlman B, Yang HY, Boice JA, Fairman R, Raleigh DP. 1997. An exceptionally stable helix from the ribosomal protein L9: Implications for protein folding and stability. J Mol Biol 270 (5): 640-647.
-
(1997)
J Mol Biol.
, vol.270
, Issue.5
, pp. 640-647
-
-
Kuhlman, B.1
Yang, H.Y.2
Boice, J.A.3
Fairman, R.4
Raleigh, D.P.5
-
364
-
-
38349150992
-
The impact of drying method and formulation on the physical properties and stability of methionyl human growth hormone in the amorphous solid state
-
Abdul-Fattah AM, Lechuga-Ballesteros D, Kalonia DS, Pikal MJ. 2008. The impact of drying method and formulation on the physical properties and stability of methionyl human growth hormone in the amorphous solid state. J Pharm Sci 97 (1): 163-184.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.1
, pp. 163-184
-
-
Abdul-Fattah, A.M.1
Lechuga-Ballesteros, D.2
Kalonia, D.S.3
Pikal, M.J.4
-
365
-
-
44449083190
-
Stability of lyophilized human growth hormone
-
Salnikova MS, Middaugh CR, Rytting JH. 2008. Stability of lyophilized human growth hormone. Int J Pharm 358 (1-2): 108-113.
-
(2008)
Int J Pharm.
, vol.358
, Issue.1-2
, pp. 108-113
-
-
Salnikova, M.S.1
Middaugh, C.R.2
Rytting, J.H.3
-
366
-
-
34547647078
-
Significance of local mobility in aggregation of beta-galactosidase lyophilized with trehalose, sucrose or stachyose
-
Yoshioka S, Miyazaki T, Aso Y, Kawanishi T. 2007. Significance of local mobility in aggregation of beta-galactosidase lyophilized with trehalose, sucrose or stachyose. Pharm Res 24 (9): 1660-1667.
-
(2007)
Pharm Res.
, vol.24
, Issue.9
, pp. 1660-1667
-
-
Yoshioka, S.1
Miyazaki, T.2
Aso, Y.3
Kawanishi, T.4
-
367
-
-
28444436280
-
Spray freezing into liquid versus spray-freeze drying: Influence of atomization on protein aggregation and biological activity
-
Yu Z, Johnston KP, Williams RO III. 2006. Spray freezing into liquid versus spray-freeze drying: Influence of atomization on protein aggregation and biological activity. Eur J Pharm Sci 27 (1): 9-18.
-
(2006)
Eur J Pharm Sci.
, vol.27
, Issue.1
, pp. 9-18
-
-
Yu, Z.1
Johnston, K.P.2
Williams R.O, I.I.I.3
-
368
-
-
0032703669
-
Effects of buffer composition and processing conditions on aggregation of bovine IgG during freeze-drying
-
Sarciaux JM, Mansour S, Hageman MJ, Nail SL. 1999. Effects of buffer composition and processing conditions on aggregation of bovine IgG during freeze-drying. J Pharm Sci 88 (12): 1354-1361.
-
(1999)
J Pharm Sci.
, vol.88
, Issue.12
, pp. 1354-1361
-
-
Sarciaux, J.M.1
Mansour, S.2
Hageman, M.J.3
Nail, S.L.4
-
369
-
-
48149112046
-
A specific molar ratio of stabilizer to protein is EXTERNAL FACTORS AFFECTING PROTEIN AGGREGATION 201 required for storage stability of a lyophilized monoclonal antibody
-
Cleland JL, Lam X, Kendrick B, Yang J, Yang TH, Overcashier D, Brooks D, Hsu C, Carpenter JF. 2001. A specific molar ratio of stabilizer to protein is EXTERNAL FACTORS AFFECTING PROTEIN AGGREGATION 201 required for storage stability of a lyophilized monoclonal antibody. J Pharm Sci 90 (3): 310-321.
-
(2001)
J Pharm Sci.
, vol.90
, Issue.3
, pp. 310-321
-
-
Cleland, J.L.1
Lam, X.2
Kendrick, B.3
Yang, J.4
Yang, T.H.5
Overcashier, D.6
Brooks, D.7
Hsu, C.8
Carpenter, J.F.9
-
370
-
-
84885976341
-
Stabilized human monoclonal antibody preparation
-
US6165467
-
Hagiwara H, Yuasa H, Yamamoto Y. 2000. Stabilized human monoclonal antibody preparation. US6165467.
-
(2000)
-
-
Hagiwara, H.1
Yuasa, H.2
Yamamoto, Y.3
-
371
-
-
0026546749
-
Influence of sucrose, dextran, and hydroxypropyl-beta-cyclodextrin as lyoprotectants for a freeze-dried mouse IgG2a monoclonal antibody (MN12)
-
Feb
-
Ressing ME, Jiskoot W, Talsma H, Van Ingen CW, Crommelin DJ. 1992. Influence of sucrose, dextran, and hydroxypropyl-beta-cyclodextrin as lyoprotectants for a freeze-dried mouse IgG2a monoclonal antibody (MN12). Pharm Res 9 (Feb): 266-270.
-
(1992)
Pharm Res.
, vol.9
, pp. 266-270
-
-
Ressing, M.E.1
Jiskoot, W.2
Talsma, H.3
Van Ingen, C.W.4
Crommelin, D.J.5
-
372
-
-
55449104956
-
Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations
-
Andya JD, Hsu CC, Shire SJ. 2003. Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations. AAPS PharmSci 5 (2): E10.
-
(2003)
AAPS PharmSci.
, vol.5
, Issue.2
, pp. 10
-
-
Andya, J.D.1
Hsu, C.C.2
Shire, S.J.3
-
373
-
-
0344563582
-
Freeze-dried formulation for direct 99mTc-labeling ior-egf/r3 MAb: Additives, biodistribution, and stability
-
Morales AA, Nunez-Gandolff G, Perez NP, Veliz BC, Caballero-Torres I, Duconge J, Fernandez E, Crespo FZ, Veloso A, Iznaga-Escobar N. 1999. Freeze-dried formulation for direct 99mTc-labeling ior-egf/r3 MAb: Additives, biodistribution, and stability. Nucl Med Biol 26 (6): 717-723.
-
(1999)
Nucl Med Biol.
, vol.26
, Issue.6
, pp. 717-723
-
-
Morales, A.A.1
Nunez-Gandolff, G.2
Perez, N.P.3
Veliz, B.C.4
Caballero-Torres, I.5
Duconge, J.6
Fernandez, E.7
Crespo, F.Z.8
Veloso, A.9
Iznaga-Escobar, N.10
-
374
-
-
0031664119
-
Effects of formulation and process variables on the aggregation of freeze-dried interleukin-6 (IL-6) after lyophilization and on storage
-
Lueckel B, Helk B, Bodmer D, Leuenberger H. 1998. Effects of formulation and process variables on the aggregation of freeze-dried interleukin-6 (IL-6) after lyophilization and on storage. Pharm Dev Technol 3 (3): 337-346.
-
(1998)
Pharm Dev Technol.
, vol.3
, Issue.3
, pp. 337-346
-
-
Lueckel, B.1
Helk, B.2
Bodmer, D.3
Leuenberger, H.4
-
375
-
-
0032425839
-
Effects of additives on the stability of recombinant human factor XIII during freeze-drying and storage in the dried solid
-
Kreilgaard L, Frokjaer S, Flink JM, Randolph TW, Carpenter JF. 1998. Effects of additives on the stability of recombinant human factor XIII during freeze-drying and storage in the dried solid. Arch Biochem Biophys 360 (1): 121-134.
-
(1998)
Arch Biochem Biophys.
, vol.360
, Issue.1
, pp. 121-134
-
-
Kreilgaard, L.1
Frokjaer, S.2
Flink, J.M.3
Randolph, T.W.4
Carpenter, J.F.5
-
376
-
-
0030338236
-
The characterization, stabilization, and formulation of acidic fibroblast growth factor
-
Volkin DB, Middaugh CR. 1996. The characterization, stabilization, and formulation of acidic fibroblast growth factor. Pharm Biotechnol 9: 181-217.
-
(1996)
Pharm Biotechnol.
, vol.9
, pp. 181-217
-
-
Volkin, D.B.1
Middaugh, C.R.2
-
377
-
-
0037381974
-
Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma
-
Webb SD, Cleland JL, Carpenter JF, Randolph TW. 2003. Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma. J Pharm Sci 92 (4): 715-729.
-
(2003)
J Pharm Sci.
, vol.92
, Issue.4
, pp. 715-729
-
-
Webb, S.D.1
Cleland, J.L.2
Carpenter, J.F.3
Randolph, T.W.4
-
378
-
-
12344290280
-
Spray-drying of proteins: Effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G
-
Maury M, Murphy K, Kumar S, Mauerer A, Lee G. 2005. Spray-drying of proteins: Effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G. Eur J Pharm Biopharm 59 (2): 251-261.
-
(2005)
Eur J Pharm Biopharm.
, vol.59
, Issue.2
, pp. 251-261
-
-
Maury, M.1
Murphy, K.2
Kumar, S.3
Mauerer, A.4
Lee, G.5
-
379
-
-
0032962882
-
The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody
-
Andya JD, Maa YF, Costantino HR, Nguyen PA, Dasovich N, Sweeney TD, Hsu CC, Shire SJ. 1999. The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody. Pharm Res 16 (3): 350-358.
-
(1999)
Pharm Res.
, vol.16
, Issue.3
, pp. 350-358
-
-
Andya, J.D.1
Maa, Y.F.2
Costantino, H.R.3
Nguyen, P.A.4
Dasovich, N.5
Sweeney, T.D.6
Hsu, C.C.7
Shire, S.J.8
-
380
-
-
0031914743
-
Spray-drying of air-liquid interface sensitive recombinant human growth hormone
-
Maa YF, Nguyen PA, Hsu SW. 1998. Spray-drying of air-liquid interface sensitive recombinant human growth hormone. J Pharm Sci 87 (2): 152-159.
-
(1998)
J Pharm Sci.
, vol.87
, Issue.2
, pp. 152-159
-
-
Maa, Y.F.1
Nguyen, P.A.2
Hsu, S.W.3
-
381
-
-
0036281804
-
Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations
-
Webb SD, Golledge SL, Cleland JL, Carpenter JF, Randolph TW. 2002. Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations. J Pharm Sci 91 (6): 1474-1487.
-
(2002)
J Pharm Sci.
, vol.91
, Issue.6
, pp. 1474-1487
-
-
Webb, S.D.1
Golledge, S.L.2
Cleland, J.L.3
Carpenter, J.F.4
Randolph, T.W.5
-
382
-
-
1542511345
-
Poly(lactide-co-glycolide) microsphere formulations of darbepoetin alfa: Spray drying is an alternative to encapsulation by spray-freeze drying
-
Burke PA, Klumb LA, Herberger JD, Nguyen XC, Harrell RA, Zordich M. 2004. Poly(lactide-co-glycolide) microsphere formulations of darbepoetin alfa: Spray drying is an alternative to encapsulation by spray-freeze drying. Pharm Res 21 (3): 500-506.
-
(2004)
Pharm Res.
, vol.21
, Issue.3
, pp. 500-506
-
-
Burke, P.A.1
Klumb, L.A.2
Herberger, J.D.3
Nguyen, X.C.4
Harrell, R.A.5
Zordich, M.6
-
383
-
-
1542615793
-
Protein powders for encapsulation: A comparison of spray-freeze drying and spray drying of darbepoetin alfa
-
Nguyen XC, Herberger JD, Burke PA. 2004. Protein powders for encapsulation: A comparison of spray-freeze drying and spray drying of darbepoetin alfa. Pharm Res 21 (3): 507-514.
-
(2004)
Pharm Res.
, vol.21
, Issue.3
, pp. 507-514
-
-
Nguyen, X.C.1
Herberger, J.D.2
Burke, P.A.3
-
384
-
-
0034495318
-
Protein spray-freeze drying. Effect of atomization conditions on particle size and stability
-
Costantino HR, Firouzabadian L, Hogeland K, Wu C, Beganski C, Carrasquillo KG, Cordova M, Griebenow K, Zale SE, Tracy MA. 2000. Protein spray-freeze drying. Effect of atomization conditions on particle size and stability. Pharm Res 17 (11): 1374-1383.
-
(2000)
Pharm Res.
, vol.17
, Issue.11
, pp. 1374-1383
-
-
Costantino, H.R.1
Firouzabadian, L.2
Hogeland, K.3
Wu, C.4
Beganski, C.5
Carrasquillo, K.G.6
Cordova, M.7
Griebenow, K.8
Zale, S.E.9
Tracy, M.A.10
-
385
-
-
36048983812
-
Stable sugar-based protein formulations by supercritical fluid drying
-
Jovanovic N, Bouchard A, Sutter M, Van Speybroeck M, Hofland GW, Witkamp GJ, Crommelin DJ, Jiskoot W. 2008. Stable sugar-based protein formulations by supercritical fluid drying. Int J Pharm 346 (1-2): 102-108.
-
(2008)
Int J Pharm.
, vol.346
, Issue.1-2
, pp. 102-108
-
-
Jovanovic, N.1
Bouchard, A.2
Sutter, M.3
Van Speybroeck, M.4
Hofl, G.W.5
Witkamp, G.J.6
Crommelin, D.J.7
Jiskoot, W.8
-
386
-
-
0037436016
-
Poly(ethylene glycol) as stabilizer and emulsifying agent: A novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres
-
Castellanos IJ, Crespo R, Griebenow K. 2003. Poly(ethylene glycol) as stabilizer and emulsifying agent: A novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres. J Control Release 88 (1): 135-145.
-
(2003)
J Control Release.
, vol.88
, Issue.1
, pp. 135-145
-
-
Castellanos, I.J.1
Crespo, R.2
Griebenow, K.3
-
387
-
-
34248658536
-
Stabilization of recombinant human growth hormone against emulsification-induced aggregation by pluronic surfactants during microencapsulation
-
Wei G, Lu LF, Lu WY. 2007. Stabilization of recombinant human growth hormone against emulsification-induced aggregation by pluronic surfactants during microencapsulation. Int J Pharm 338 (1-2): 125-132.
-
(2007)
Int J Pharm.
, vol.338
, Issue.1-2
, pp. 125-132
-
-
Wei, G.1
Lu, L.F.2
Lu, W.Y.3
-
388
-
-
50949096580
-
Formulating erythropoietin-loaded sustained-release PLGA microspheres without protein aggregation
-
Geng Y, Yuan W, Wu F, Chen J, He M, Jin T. 2008. Formulating erythropoietin-loaded sustained-release PLGA microspheres without protein aggregation. J Control Release 130 (3): 259-265.
-
(2008)
J Control Release.
, vol.130
, Issue.3
, pp. 259-265
-
-
Geng, Y.1
Yuan, W.2
Wu, F.3
Chen, J.4
He, M.5
Jin, T.6
-
389
-
-
0033039914
-
Stabilization of proteins against methylene chloride/water interface-induced denaturation and aggregation
-
Sah H. 1999. Stabilization of proteins against methylene chloride/water interface-induced denaturation and aggregation. J Control Release 58 (2): 143-151.
-
(1999)
J Control Release.
, vol.58
, Issue.2
, pp. 143-151
-
-
Sah, H.1
-
390
-
-
0032876495
-
Stabilization of aerosolized IFN-gamma by liposomes
-
Kanaoka E, Nagata S, Hirano K. 1999. Stabilization of aerosolized IFN-gamma by liposomes. Int J Pharm 188 (2): 165-172.
-
(1999)
Int J Pharm.
, vol.188
, Issue.2
, pp. 165-172
-
-
Kanaoka, E.1
Nagata, S.2
Hirano, K.3
-
391
-
-
0029134661
-
Stability of recombinant consensus interferon to air-jet and ultrasonic nebulization
-
Ip AY, Arakawa T, Silvers H, Ransone CM, Niven RW. 1995. Stability of recombinant consensus interferon to air-jet and ultrasonic nebulization. J Pharm Sci 84 (10): 1210-1214.
-
(1995)
J Pharm Sci.
, vol.84
, Issue.10
, pp. 1210-1214
-
-
Ip, A.Y.1
Arakawa, T.2
Silvers, H.3
Ransone, C.M.4
Niven, R.W.5
-
392
-
-
0142106018
-
L-tyrosine prevents aggregation of therapeutic proteins by gamma-irradiation
-
Assemand E, Lacroix M, Mateescu MA. 2003. L-tyrosine prevents aggregation of therapeutic proteins by gamma-irradiation. Biotechnol Appl Biochem 38 (Pt 2): 151-156.
-
(2003)
Biotechnol Appl Biochem.
, vol.38
, Issue.2 PT
, pp. 151-156
-
-
Assemand, E.1
Lacroix, M.2
Mateescu, M.A.3
-
393
-
-
42749087238
-
Stability of proteins encapsulated in injectable and biodegradable poly(lactide-co-glycolide)-glucose millicylinders
-
Kang J, Lambert O, Ausborn M, Schwendeman SP. 2008. Stability of proteins encapsulated in injectable and biodegradable poly(lactide-co-glycolide)-glucose millicylinders. Int J Pharm 357 (1-2): 235-243.
-
(2008)
Int J Pharm.
, vol.357
, Issue.1-2
, pp. 235-243
-
-
Kang, J.1
Lambert, O.2
Ausborn, M.3
Schwendeman, S.P.4
-
394
-
-
0028875052
-
Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form
-
Costantino HR, Griebenow K, Mishra P, Langer R, Klibanov AM. 1995. Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form. Biochim Biophys Acta 1253 (1): 69-74.
-
(1995)
Biochim Biophys Acta.
, vol.1253
, Issue.1
, pp. 69-74
-
-
Costantino, H.R.1
Griebenow, K.2
Mishra, P.3
Langer, R.4
Klibanov, A.M.5
-
395
-
-
23844447975
-
Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
-
Chang LL, Shepherd D, Sun J, Ouellette D, Grant KL, Tang XC, Pikal MJ. 2005. Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix? J Pharm Sci 94 (7): 1427-1444.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.7
, pp. 1427-1444
-
-
Chang, L.L.1
Shepherd, D.2
Sun, J.3
Ouellette, D.4
Grant, K.L.5
Tang, X.C.6
Pikal, M.J.7
-
396
-
-
0026356940
-
The effects of formulation and moisture on the stability of a freeze-dried monoclonal antibody-vinca conjugate: A test of the WLF glass transition theory
-
discussion 340
-
Roy ML, Pikal MJ, Rickard EC, Maloney AM. 1992. The effects of formulation and moisture on the stability of a freeze-dried monoclonal antibody-vinca conjugate: A test of the WLF glass transition theory. Dev Biol Stand 74: 323-339; discussion 340.
-
(1992)
Dev Biol Stand.
, vol.74
, pp. 323-339
-
-
Roy, M.L.1
Pikal, M.J.2
Rickard, E.C.3
Maloney, A.M.4
-
397
-
-
57349122408
-
Solid state chemistry of proteins: II. The correlation of storage stability of freeze-dried human growth hormone (hGH) with structure and dynamics in the glassy solid
-
Pikal MJ, Rigsbee D, Roy ML, Galreath D, Kovach KJ, Wang BS, Carpenter JF, Cicerone MT. 2008. Solid state chemistry of proteins: II. The correlation of storage stability of freeze-dried human growth hormone (hGH) with structure and dynamics in the glassy solid. J Pharm Sci 97 (12): 5106-5121.
-
(2008)
J Pharm Sci.
, vol.97
, Issue.12
, pp. 5106-5121
-
-
Pikal, M.J.1
Rigsbee, D.2
Roy, M.L.3
Galreath, D.4
Kovach, K.J.5
Wang, B.S.6
Carpenter, J.F.7
Cicerone, M.T.8
-
398
-
-
48149089155
-
Role of trehalose in moisture-induced aggregation of bovine serum albumin
-
Jain NK, Roy I. 2008. Role of trehalose in moisture-induced aggregation of bovine serum albumin. Eur J Pharm Biopharm 69 (3): 824-834.
-
(2008)
Eur J Pharm Biopharm.
, vol.69
, Issue.3
, pp. 824-834
-
-
Jain, N.K.1
Roy, I.2
-
399
-
-
0030044405
-
Development of a stable freeze-dried formulation of recombinant human interleukin-1 receptor antagonist
-
Chang BS, Reeder G, Carpenter JF. 1996. Development of a stable freeze-dried formulation of recombinant human interleukin-1 receptor antagonist. Pharm Res 13 (2): 243-249.
-
(1996)
Pharm Res.
, vol.13
, Issue.2
, pp. 243-249
-
-
Chang, B.S.1
Reeder, G.2
Carpenter, J.F.3
-
400
-
-
0026527801
-
Lyophilized formulations of recombinant tumor necrosis factor
-
Hora MS, Rana RK, Smith FW. 1992. Lyophilized formulations of recombinant tumor necrosis factor. Pharm Res 9 (1): 33-36.
-
(1992)
Pharm Res.
, vol.9
, Issue.1
, pp. 33-36
-
-
Hora, M.S.1
Rana, R.K.2
Smith, F.W.3
-
401
-
-
1542619712
-
Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures
-
Garzon-Rodriguez W, Koval RL, Chongprasert S, Krishnan S, Randolph TW, Warne NW, Carpenter JF. 2004. Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures. J Pharm Sci 93 (3): 684-696.
-
(2004)
J Pharm Sci.
, vol.93
, Issue.3
, pp. 684-696
-
-
Garzon-Rodriguez, W.1
Koval, R.L.2
Chongprasert, S.3
Krishnan, S.4
Randolph, T.W.5
Warne, N.W.6
Carpenter, J.F.7
-
402
-
-
0030997388
-
Solid-state stability of human insulin
-
II. Effect of water on reactive intermediate partitioning in lyophiles from pH. 2-5 solutions: Stabilization against covalent dimer formation
-
Strickley RG, Anderson BD. 1997. Solid-state stability of human insulin. II. Effect of water on reactive intermediate partitioning in lyophiles from pH 2-5 solutions: Stabilization against covalent dimer formation. J Pharm Sci 86 (6): 645-653.
-
(1997)
J Pharm Sci.
, vol.86
, Issue.6
, pp. 645-653
-
-
Strickley, R.G.1
Anderson, B.D.2
-
403
-
-
0032969861
-
Effects of additives on the stability of Humicola lanuginosa lipase during freeze-drying and storage in the dried solid
-
Kreilgaard L, Frokjaer S, Flink JM, Randolph TW, Carpenter JF. 1999. Effects of additives on the stability of Humicola lanuginosa lipase during freeze-drying and storage in the dried solid. J Pharm Sci 88 (3): 281-290.
-
(1999)
J Pharm Sci.
, vol.88
, Issue.3
, pp. 281-290
-
-
Kreilgaard, L.1
Frokjaer, S.2
Flink, J.M.3
Randolph, T.W.4
Carpenter, J.F.5
-
404
-
-
0030470871
-
The secondary structure and aggregation of lyophilized tetanus toxoid
-
Costantino HR, Schwendeman SP, Griebenow K, Klibanov AM, Langer R. 1996. The secondary structure and aggregation of lyophilized tetanus toxoid. J Pharm Sci 85 (12): 1290-1293.
-
(1996)
J Pharm Sci.
, vol.85
, Issue.12
, pp. 1290-1293
-
-
Costantino, H.R.1
Schwendeman, S.P.2
Griebenow, K.3
Klibanov, A.M.4
Langer, R.5
-
405
-
-
1842482434
-
Raman spectroscopic characterization of drying-induced structural changes in a therapeutic antibody: Correlating structural changes with long-term stability
-
Sane SU, Wong R, Hsu CC. 2004. Raman spectroscopic characterization of drying-induced structural changes in a therapeutic antibody: Correlating structural changes with long-term stability. J Pharm Sci 93 (4): 1005-1018.
-
(2004)
J Pharm Sci.
, vol.93
, Issue.4
, pp. 1005-1018
-
-
Sane, S.U.1
Wong, R.2
Hsu, C.C.3
-
406
-
-
0031793406
-
Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized anti-IgE monoclonal antibody
-
Costantino HR, Andya JD, Nguyen PA, Dasovich N, Sweeney TD, Shire SJ, Hsu CC, Maa YF. 1998. Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized anti-IgE monoclonal antibody. J Pharm Sci 87 (11): 1406-1411.
-
(1998)
J Pharm Sci.
, vol.87
, Issue.11
, pp. 1406-1411
-
-
Costantino, H.R.1
Andya, J.D.2
Nguyen, P.A.3
Dasovich, N.4
Sweeney, T.D.5
Shire, S.J.6
Hsu, C.C.7
Maa, Y.F.8
-
407
-
-
0026071674
-
Moisture-induced aggregation of lyophilized proteins in the solid state
-
Liu WR, Langer R, Klibanov AM. 1990. Moisture-induced aggregation of lyophilized proteins in the solid state. Biotechnol Bioeng 37: 177-184.
-
(1990)
Biotechnol Bioeng.
, vol.37
, pp. 177-184
-
-
Liu, W.R.1
Langer, R.2
Klibanov, A.M.3
-
408
-
-
0029071504
-
Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: Effect of moisture and stabilization by excipients
-
Costantino HR, Langer R, Klibanov AM. 1995. Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: Effect of moisture and stabilization by excipients. Biotechnology (N Y) 13 (5): 493-496.
-
(1995)
Biotechnology (N Y).
, vol.13
, Issue.5
, pp. 493-496
-
-
Costantino, H.R.1
Langer, R.2
Klibanov, A.M.3
-
409
-
-
0026328935
-
Development of a lyophilized formulation of interleukin-2
-
Hora MS, Rana RK, Wilcox CL, Katre NV, Hirtzer P, Wolfe SN, Thomson JW. 1992. Development of a lyophilized formulation of interleukin-2. Dev Biol Stand 74: 295-303.
-
(1992)
Dev Biol Stand.
, vol.74
, pp. 295-303
-
-
Hora, M.S.1
Rana, R.K.2
Wilcox, C.L.3
Katre, N.V.4
Hirtzer, P.5
Wolfe, S.N.6
Thomson, J.W.7
-
410
-
-
0032958279
-
Influence of calcium ions on the structure and stability of recombinant human deoxyribonuclease I in the aqueous and lyophilized states
-
Chen B, Costantino HR, Liu J, Hsu CC, Shire SJ. 1999. Influence of calcium ions on the structure and stability of recombinant human deoxyribonuclease I in the aqueous and lyophilized states. J Pharm Sci 88 (4): 477-482.
-
(1999)
J Pharm Sci.
, vol.88
, Issue.4
, pp. 477-482
-
-
Chen, B.1
Costantino, H.R.2
Liu, J.3
Hsu, C.C.4
Shire, S.J.5
-
411
-
-
0029093065
-
Aggregation of insulin and its prevention by carbohydrate excipients
-
Katakam M, Banga AK. 1995. Aggregation of insulin and its prevention by carbohydrate excipients. PDA J Pharm Sci Technol 49 (4): 160-165.
-
(1995)
PDA J Pharm Sci Technol.
, vol.49
, Issue.4
, pp. 160-165
-
-
Katakam, M.1
Banga, A.K.2
-
412
-
-
0034854492
-
Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation
-
Breen ED, Curley JG, Overcashier DE, Hsu CC, Shire SJ. 2001. Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation. Pharm Res 18 (9): 1345-1353.
-
(2001)
Pharm Res.
, vol.18
, Issue.9
, pp. 1345-1353
-
-
Breen, E.D.1
Curley, J.G.2
Overcashier, D.E.3
Hsu, C.C.4
Shire, S.J.5
-
413
-
-
33846140511
-
Protein Formulation
-
Genentech, Inc. US6685940 B2
-
Andya J, Cleland JL, Hsu CC, Lam XM, Overcashier DE, Shire SJ, Yang JY-F, Wu SS-Y. 2004. Protein Formulation. Genentech, Inc. US6685940 B2.
-
(2004)
-
-
Andya, J.1
Cleland, J.L.2
Hsu, C.C.3
Lam, X.M.4
Overcashier, D.E.5
Shire, S.J.6
Yang, J.Y.-F.7
Wu, S.S-Y.8
-
414
-
-
23844447975
-
Mechanism of protein stabilization by sugars during freeze-drying and storage: 204 AGGREGATION OF THERAPEUTIC PROTEINS Native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
-
Chang LL, Shepherd D, Sun J, Ouellette D, Grant KL, Tang XC, Pikal MJ. 2005. Mechanism of protein stabilization by sugars during freeze-drying and storage: 204 AGGREGATION OF THERAPEUTIC PROTEINS Native structure preservation, specific interaction, and/or immobilization in a glassy matrix? J Pharm Sci 94 (7): 1427-1444.
-
(2005)
J Pharm Sci.
, vol.94
, Issue.7
, pp. 1427-1444
-
-
Chang, L.L.1
Shepherd, D.2
Sun, J.3
Ouellette, D.4
Grant, K.L.5
Tang, X.C.6
Pikal, M.J.7
-
415
-
-
34147175003
-
Aggregation of beta-lactoglobulin regulated by glucosylation
-
Broersen K, Elshof M, de Groot J, Voragen AGJ, Hamer RJ, de Jongh HHJ. 2007. Aggregation of beta-lactoglobulin regulated by glucosylation. J Agric Food Chem 55 (6): 2431-2437.
-
(2007)
J Agric Food Chem.
, vol.55
, Issue.6
, pp. 2431-2437
-
-
Broersen, K.1
Elshof, M.2
De Groot, J.3
Voragen, A.G.J.4
Hamer, R.J.5
De Jongh, H.H.J.6
-
416
-
-
85009900563
-
Glass transition and product stability-An overview
-
Schenz TW. 1995. Glass transition and product stability-An overview. Food Hydrocolloids 9: 307-315.
-
(1995)
Food Hydrocolloids.
, vol.9
, pp. 307-315
-
-
Schenz, T.W.1
-
417
-
-
67449138534
-
Solid state chemistry of proteins IV
-
What is the meaning of thermal denaturation in freeze dried proteins?
-
Pikal MJ, Rigsbee D, Akers MJ. 2009. Solid state chemistry of proteins IV. What is the meaning of thermal denaturation in freeze dried proteins? J Pharm Sci 98 (4): 1387-1399.
-
(2009)
J Pharm Sci.
, vol.98
, Issue.4
, pp. 1387-1399
-
-
Pikal, M.J.1
Rigsbee, D.2
Akers, M.J.3
-
418
-
-
0034854492
-
Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation
-
Breen ED, Curley JG, Overcashier DE, Hsu CC, Shire SJ. 2001. Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation. Pharm Res 18 (9): 1345-1353.
-
(2001)
Pharm Res.
, vol.18
, Issue.9
, pp. 1345-1353
-
-
Breen, E.D.1
Curley, J.G.2
Overcashier, D.E.3
Hsu, C.C.4
Shire, S.J.5
-
419
-
-
0031780284
-
Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders
-
May
-
Maa YF, Nguyen PA, Andya JD, Dasovich N, Hsu CC, et al. 1998. Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders. Pharm Res 15 (May): 768-775.
-
(1998)
Pharm Res.
, vol.15
, pp. 768-775
-
-
Maa, Y.F.1
Nguyen, P.A.2
Andya, J.D.3
Dasovich, N.4
Hsu, C.C.5
-
420
-
-
0034954471
-
Characterization of murine monoclonal antibody to tumor necrosis factor (TNF-MAb) formulation for freeze drying cycle development
-
Feb
-
Ma X, Wang DQ, Bouffard R, MacKenzie A. 2001. Characterization of murine monoclonal antibody to tumor necrosis factor (TNF-MAb) formulation for freeze drying cycle development. Pharm Res 18 (Feb): 196-202.
-
(2001)
Pharm Res.
, vol.18
, pp. 196-202
-
-
Ma, X.1
Wang, D.Q.2
Bouffard, R.3
MacKenzie, A.4
-
421
-
-
0032425197
-
A solid-state NMR study of protein hydration and stability
-
Separovic F, Lam YH, Ke X, Chan HK. 1998. A solid-state NMR study of protein hydration and stability. Pharm Res 15 (12): 1816-1821.
-
(1998)
Pharm Res.
, vol.15
, Issue.12
, pp. 1816-1821
-
-
Separovic, F.1
Lam, Y.H.2
Ke, X.3
Chan, H.K.4
-
422
-
-
0030339449
-
Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine
-
Schwendeman SP, Costantino HR, Gupta RK, Tobio M, Chang AC, Alonso MJ, Siber GR, Langer R. 1996. Strategies for stabilising tetanus toxoid towards the development of a single-dose tetanus vaccine. Dev Biol Stand 87: 293-306.
-
(1996)
Dev Biol Stand.
, vol.87
, pp. 293-306
-
-
Schwendeman, S.P.1
Costantino, H.R.2
Gupta, R.K.3
Tobio, M.4
Chang, A.C.5
Alonso, M.J.6
Siber, G.R.7
Langer, R.8
-
423
-
-
0032834037
-
Structural investigation of beta-lactoglobulin gelation in ethanol/water solutions
-
Renard D, Lefebvre J, Robert P, Llamas G, Dufour E, Dufour E. 1999. Structural investigation of beta-lactoglobulin gelation in ethanol/water solutions. Int J Biol Macromol 26 (1): 35-44.
-
(1999)
Int J Biol Macromol.
, vol.26
, Issue.1
, pp. 35-44
-
-
Renard, D.1
Lefebvre, J.2
Robert, P.3
Llamas, G.4
Dufour, E.5
Dufour, E.6
-
424
-
-
0342762048
-
Protein denaturation by combined effect of shear and air-liquid interface
-
Maa Y-F, Hsu CC. 1997. Protein denaturation by combined effect of shear and air-liquid interface. Biotechnol Bioeng 54 (6): 503-512.
-
(1997)
Biotechnol Bioeng.
, vol.54
, Issue.6
, pp. 503-512
-
-
Maa, Y.-F.1
Hsu, C.C.2
-
425
-
-
0004780476
-
High-pressure effects on vacuolar H +-ATPase from etiolated mung bean seedlings
-
Tsai YR, Yang SJ, Jiang SS, Ko SJ, Hung SH, Kuo SY, Pan RL. 1998. High-pressure effects on vacuolar H +-ATPase from etiolated mung bean seedlings. J Protein Chem 17 (2): 161-172.
-
(1998)
J Protein Chem.
, vol.17
, Issue.2
, pp. 161-172
-
-
Tsai, Y.R.1
Yang, S.J.2
Jiang, S.S.3
Ko, S.J.4
Hung, S.H.5
Kuo, S.Y.6
Pan, R.L.7
-
426
-
-
0027164091
-
Formulation design of acidic fibroblast growth factor
-
Tsai PK, Volkin DB, Dabora JM, Thompson KC, Bruner MW, Gress JO, Matuszewska B, Keogan M, Bondi JV, Middaugh CR. 1993. Formulation design of acidic fibroblast growth factor. Pharm Res 10 (5): 649-659.
-
(1993)
Pharm Res.
, vol.10
, Issue.5
, pp. 649-659
-
-
Tsai, P.K.1
Volkin, D.B.2
Dabora, J.M.3
Thompson, K.C.4
Bruner, M.W.5
Gress, J.O.6
Matuszewska, B.7
Keogan, M.8
Bondi, J.V.9
Middaugh, C.R.10
-
427
-
-
35748948052
-
Thermal aggregation of beta-lactoglobulin in presence of metal ions
-
Navarra G, Leone M, Militello V. 2007. Thermal aggregation of beta-lactoglobulin in presence of metal ions. Biophys Chem 131 (13): 52-61.
-
(2007)
Biophys Chem.
, vol.131
, Issue.13
, pp. 52-61
-
-
Navarra, G.1
Leone, M.2
Militello, V.3
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