Molten globule intermediate of recombinant human growth hormone: Stabilization with surfactants

Biotechnology Progress

Volumn 12, Issue 6, 1996, Pages 801-809

  Bam, Narendra B ^a   Cleland, Jeffrey L ^b   Randolph, Theodore W ^c  

^a Yale University   (United States)

^b GENENTECH INC   (United States)

^c University of Colorado at Boulder   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; CONFORMATIONS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FLUORESCENCE; PROTEINS; SURFACE ACTIVE AGENTS;

GUANIDINIUM HYDROCHLORIDE (GUHCL); HYDROPHOBIC PROBE; MOLTEN GLOBULE INTERMEDIATE; RECOMBINANT HUMAN GROWTH HORMONE (RHGH);

HORMONES;

1-ANILINO-8-NAPHTHALENESULFONATE; 8 ANILINO 1 NAPHTHALENESULFONIC ACID; FLUORESCENT DYE; HUMAN GROWTH HORMONE; RECOMBINANT PROTEIN; SURFACTANT;

ARTICLE; CHEMISTRY; CIRCULAR DICHROISM; DRUG STABILITY; ELECTRON SPIN RESONANCE; HUMAN; MIDDLE AGED; PROTEIN DENATURATION; PROTEIN FOLDING; SPECTROFLUOROMETRY;

ANILINO NAPHTHALENESULFONATES; CIRCULAR DICHROISM; DRUG STABILITY; ELECTRON SPIN RESONANCE SPECTROSCOPY; FLUORESCENT DYES; HUMAN GROWTH HORMONE; HUMANS; MIDDLE AGED; PROTEIN DENATURATION; PROTEIN FOLDING; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; SURFACE-ACTIVE AGENTS;

EID: 0030292616     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp960068b     Document Type: Article

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