A transient expansion of the native state precedes aggregation of recombinant human interferon-γ

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 24, 1998, Pages 14142-14146

  Kendrick, Brent S ^a,d   Carpenter, John F ^a   Cleland, Jeffrey L ^b   Randolph, Theodore W ^c  

^a UNIVERSITY OF COLORADO   (United States)

^b GENENTECH INC   (United States)

^c UCB 450   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT GAMMA INTERFERON;

ARTICLE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE; THERMODYNAMICS;

CHROMATOGRAPHY, GEL; ESCHERICHIA COLI; GUANIDINE; HUMANS; INTERFERON-GAMMA, RECOMBINANT; KINETICS; LIGHT; MODELS, CHEMICAL; PROTEIN BINDING; SCATTERING, RADIATION; SUCROSE; SURFACE TENSION;

EID: 0032564420     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.24.14142     Document Type: Article

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