Protein aggregation and bioprocessing

AAPS Journal

Volumn 8, Issue 3, 2006, Pages

  Cromwell, Mary E M ^a   Hilario, Eric ^a   Jacobson, Fred ^a  

^a GENENTECH INC   (United States)

Author keywords

Aggregation; Cell culture; Filling; Manufacture; Purification; Self association

Indexed keywords

ALEMTUZUMAB; DISULFIDE; FILLER; MONOCLONAL ANTIBODY; PROTEIN;

AFFINITY CHROMATOGRAPHY; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BIOPROCESS; CELL CULTURE; CONCENTRATION (PARAMETERS); COVALENT BOND; CULTURE MEDIUM; DIAFILTRATION; DISULFIDE BOND; DRUG FORMULATION; ELUTION; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; ION EXCHANGE CHROMATOGRAPHY; IONIC STRENGTH; PARTICLE SIZE; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROCESS MONITORING; PROTEIN AGGREGATION; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; QUALITY CONTROL; TEMPERATURE; TURBIDITY; ULTRAFILTRATION; VISCOSITY;

CELL CULTURE TECHNIQUES; CHEMISTRY, PHARMACEUTICAL; HYDROPHOBICITY; PARTICLE SIZE; PROTEINS;

EID: 33749057744     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/aapsj080366     Document Type: Article

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