Small molecule inhibitors of aggregation indicate that amyloid β oligomerization and fibrillization pathways are independent and distinct

Journal of Biological Chemistry

Volumn 282, Issue 14, 2007, Pages 10311-10324

  Necula, Mihaela ^a   Kayed, Rakez ^a   Milton, Saskia ^a   Glabe, Charles G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b 3438 McGaugh Hall ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; FIBRILLIZATION; PROTEIN AGGREGATION; THERAPEUTIC AGENTS;

DISEASES; OLIGOMERIZATION; OLIGOMERS; PATHOLOGY; STOICHIOMETRY;

PEPTIDES;

1,2 NAPHTHOQUINONE; 2,2' DIHYDROXYBENZOPHENONE; 2,9 DIMETHYL 1,10 PHENANTHROLINE; AMYLOID BETA PROTEIN; AZURE C; BASIC BLUE 41; CETRIMIDE; CONGO RED; CURCUMIN; DAUNORUBICIN; EOSIN; HEMATIN; HEMIN; INDOMETACIN; JUGLONE; LACMOID; MECLOCYCLINE SULFOSALICYLATE; MEPACRINE MUSTARD; MYRICETIN; NORAPOMORPHINE HYDROBROMIDE; NORDIHYDROGUAIARETIC ACID; OLIGOMER; PHENOLSULFONPHTHALEIN; PHERPHENAZINE; PROTEIN INHIBITOR; RHODAMINE B; RIFAMYCIN; ROLITETRACYCLINE; TRIMETHYL(TETRADECYL)AMMONIUM BROMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; AMYLOID;

ARTICLE; CONCENTRATION RESPONSE; DRUG TARGETING; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; STOICHIOMETRY; ALZHEIMER DISEASE; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; HUMAN; METABOLISM; PATHOLOGY; PROTEIN QUATERNARY STRUCTURE; SENILE PLAQUE; THERMODYNAMICS; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; ANIMALS; HUMANS; PROTEIN STRUCTURE, QUATERNARY; SENILE PLAQUES; THERMODYNAMICS;

EID: 34249860495     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608207200     Document Type: Article

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