Nature and consequences of protein-protein interactions in high protein concentration solutions

International Journal of Pharmaceutics

Volumn 358, Issue 1-2, 2008, Pages 1-15

  Saluja, Atul ^a   Kalonia, Devendra S ^b  

^a AMGEN INC   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Aggregation; High protein concentration solutions; Protein protein interactions; Rheology; Self association; Virial coefficient; Viscoelasticity; Viscosity

Indexed keywords

SOLVENT;

CONCENTRATION (PARAMETERS); DRUG FORMULATION; DRUG INDUSTRY; FLOW KINETICS; HIGH PROTEIN CONCENTRATION SOLUTION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; REVIEW; SHELF LIFE; SOLUTE; SOLUTION AND SOLUBILITY; THERMODYNAMICS; VISCOELASTICITY;

ANIMALS; CHEMISTRY, PHYSICAL; DRUG STABILITY; HUMANS; PROTEINS; RHEOLOGY; SOLUTIONS; THERMODYNAMICS; VISCOSITY;

EID: 44449108578     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.03.041     Document Type: Review

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