Non-native intermediate conformational states of human growth hormone in the presence of organic solvents

Pharmaceutical Research

Volumn 22, Issue 5, 2005, Pages 789-796

  Sukumar, Muppalla ^a   Storms, Sacha M ^a   De Felippis, Michael R ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Circular dichroism; Fluorescence anisotropy; Light scattering; Protein folding; Protein structure; Solvent effects

Indexed keywords

ALCOHOL; HUMAN GROWTH HORMONE; ORGANIC SOLVENT; TRYPTOPHAN;

ANISOTROPY; AQUEOUS SOLUTION; ARTICLE; CIRCULAR DICHROISM; DRUG STRUCTURE; FLUORESCENCE SPECTROSCOPY; HORMONE STRUCTURE; HYDRODYNAMICS; LIGHT SCATTERING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; ULTRAVIOLET RADIATION;

CHEMISTRY, PHARMACEUTICAL; CIRCULAR DICHROISM; ETHANOL; FLUORESCENCE POLARIZATION; HUMAN GROWTH HORMONE; HUMANS; LIGHT; MOLECULAR CONFORMATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; SCATTERING, RADIATION; SOLVENTS; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 20044383430     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-005-2596-5     Document Type: Article

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