Temperature dependence of benzyl alcohol- and 8-anilinonaphthalene-1- sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist

Biochemistry

Volumn 45, Issue 12, 2006, Pages 3898-3911

  Roy, Shouvik ^a   Katayama, Derrick ^a   Dong, Aichun ^b   Kerwin, Bruce A ^c   Randolph, Theodore W ^d   Carpenter, John F ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF NORTHERN COLORADO   (United States)

^c AMGEN INC   (United States)

^d UCB 450   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; ALCOHOLS; PERTURBATION TECHNIQUES; REACTION KINETICS; TITRATION;

HUMAN INTERLEUKIN-1 RECEPTORS; PROTEIN AGGREGATION; TEMPERATURE DEPENDENCE;

PROTEINS;

8 ANILINO 1 NAPHTHALENESULFONIC ACID; BENZYL ALCOHOL; BUFFER; CYSTEINE; LIGAND; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SULFONIC ACID DERIVATIVE;

ARTICLE; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; KINETICS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REACTION ANALYSIS; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

ANILINO NAPHTHALENESULFONATES; BENZYL ALCOHOL; CIRCULAR DICHROISM; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SIALOGLYCOPROTEINS; SPECTROPHOTOMETRY, ULTRAVIOLET; TEMPERATURE; THERMODYNAMICS;

EID: 33645451427     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052132g     Document Type: Article

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