Stabilization of recombinant human growth hormone against emulsification-induced aggregation by Pluronic surfactants during microencapsulation

International Journal of Pharmaceutics

Volumn 338, Issue 1-2, 2007, Pages 125-132

  Wei, Gang ^a   Lu, Li Fang ^a   Lu, Wei Yue ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Emulsification; Microspheres; Pluronic; Protein stability; Recombinant human growth hormone (rhGH)

Indexed keywords

DICHLOROMETHANE; HUMAN GROWTH HORMONE; MICROSPHERE; POLOXAMER; POLYOL; POLYSORBATE 20; SUCROSE; SURFACTANT;

ARTICLE; DRUG FORMULATION; DRUG PURIFICATION; DRUG RELEASE; DRUG STABILITY; EMULSION; MICROENCAPSULATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; SCANNING ELECTRON MICROSCOPY;

DRUG STABILITY; EMULSIONS; EXCIPIENTS; HUMAN GROWTH HORMONE; LACTIC ACID; MICROSPHERES; POLOXAMER; POLYGLYCOLIC ACID; POLYMERS; RECOMBINANT PROTEINS; SOLUBILITY; SURFACE-ACTIVE AGENTS;

EID: 34248658536     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.01.043     Document Type: Article

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