Development of a stable freeze-dried formulation of recombinant human interleukin-1 receptor antagonist

Pharmaceutical Research

Volumn 13, Issue 2, 1996, Pages 243-249

  Chang, Byeong S ^a   Reeder, Gail ^a   Carpenter, John F ^b  

^a AMGEN INC   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Freeze dried formulation; Protein stability; rhIL 1ra

Indexed keywords

RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ARTICLE; DRUG DEGRADATION; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL;

BUFFERS; CATIONS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; FREEZE DRYING; HUMANS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; SIALOGLYCOPROTEINS; TEMPERATURE; VEHICLES; WATER;

EID: 0030044405     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016043114998     Document Type: Article

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