A solid-state NMR study of protein hydration and stability

Pharmaceutical Research

Volumn 15, Issue 12, 1998, Pages 1816-1821

  Separovic, F ^a   Lam, Y H ^a   Ke, X ^b   Chan, H K ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Activity; Aggregation; Bound water; NMR relaxation time; Protein mobility

Indexed keywords

DEOXYRIBONUCLEASE I; INSULIN; LYSOZYME; WATER;

ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DEUTERON NUCLEAR MAGNETIC RESONANCE; ENZYME ACTIVITY; FREEZE DRYING; GEL PERMEATION CHROMATOGRAPHY; HUMIDITY; HYDRATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POWDER; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN STABILITY; PROTON NUCLEAR MAGNETIC RESONANCE; WATER CONTENT;

CARBON ISOTOPES; DEOXYRIBONUCLEASES; ENZYME ACTIVATION; FREEZE DRYING; HUMANS; HYDROGEN BONDING; INSULIN; MURAMIDASE; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXYGEN ISOTOPES; PROTEIN BINDING; PROTONS; RECOMBINANT PROTEINS; SPECIMEN HANDLING; WATER;

EID: 0032425197     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011993620177     Document Type: Article

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