메뉴 건너뛰기




Volumn 10, Issue 1, 2012, Pages 12-48

Therapeutic potential of metabotropic glutamate receptor modulators

Author keywords

Addiction; Alzheimer's disease; Anxiety; Depression; Epilepsy; Fragile X syndrome; Huntington's disease; Metabotropic glutamate receptors; Pain; Parkinson's disease; Schizophrenia

Indexed keywords

(4 FLUOROPHENYL) [3 [3 (4 FLUOROPHENYL) [1,2,4] OXADIAZOL 5 YL]PIPERIDIN 1 YL]METHANONE; 1 [2 HYDROXY 3 METHYL 4 [4 [4 (2H TETRAZOL 5 YL)PHENOXY]BUTOXY]PHENYL]ETHANONE; 1 AMINO 1,5 INDANDICARBOXYLIC ACID; 1 AMINOCYCLOPENTANE 1,3,4 TRICARBOXYLIC ACID; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 2 AMINO 2 (3 CARBOXYCYCLOBUTYL) 3 (9 THIOXANTHYL)PROPIONIC ACID; 2 AMINO 2 (4 CARBOXYPHENYL) 3 (9 THIOXANTHYL)PROPIONIC ACID; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 3 CYANO N (1,3 DIPHENYL 1H PYRAZOL 5 YL)BENZAMIDE; 3,5 DIHYDROXYPHENYLGLYCINE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; 4 AMINO 2 THIABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; 4 AMINO 2 THIABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID 2,2 DIOXIDE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; 4 CARBOXYPHENYLGLYCINE; 4 PHOSPHONOPHENYLGLYCINE; 6A NAPHTALEN 2 YL METHYL 5 METHYLIDEN HEXAHYDROCYCLOPENTAL[C]FURAN 1 ON]; 9 DIMETHYLAMINO 3 (4 ETHYLPHENYL) 3H 5 THIA 1,3,6 TRIAZAFLUOREN 4 ONE; 9 DIMETHYLAMINO 3 (4 METHYLPHENYL) 3H 5 THIA 1,3,7 TRIAZAFLUOREN 4 ONE; 9 DIMETHYLAMINO 3 (N HEXAMETHYLENEIMINYL) 3H 5 THIA 1,3,6 TRIAZAFLUOREN 4 ONE; 9 DIMETHYLAMINO 3 CYCLOHEPTYL 3H 5 THIA 1,3,6 TRIAZAFLUOREN 4 ONE; A 794278; A 794282; A 841720; A 850002; BIPHENYLINDANONE A; EGLUMETAD; GLUTAMATE CARBOXYPEPTIDASE II; LY 339764; LY 339840; LY 367335; LY 456066; LY 456236; LY 487379; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; N,N' DIBENZHYDRYLETHANE 1,2 DIAMINE DIHYDROCHLORIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84857705629     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/157015912799362805     Document Type: Review
Times cited : (79)

References (406)
  • 1
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • Conn, P. J.; Pin, J. P. Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol., 1997, 37, 205-237.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 205-237
    • Conn, P.J.1    Pin, J.P.2
  • 2
    • 0028912822 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin, J. P.; Duvoisin, R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology, 1995, 34 (1), 1-26.
    • (1995) Neuropharmacology , vol.34 , Issue.1 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 3
    • 0035812645 scopus 로고    scopus 로고
    • Neuroprotective and behavioral effects of the selective metabotropic glutamate mGlu(1) receptor antagonist BAY 36-7620
    • De Vry, J.; Horvath, E.; Schreiber, R. Neuroprotective and behavioral effects of the selective metabotropic glutamate mGlu(1) receptor antagonist BAY 36-7620. Eur. J. Pharmacol., 2001, 428 (2), 203-214.
    • (2001) Eur. J. Pharmacol. , vol.428 , Issue.2 , pp. 203-214
    • de Vry, J.1    Horvath, E.2    Schreiber, R.3
  • 4
    • 0026093312 scopus 로고
    • Sequence and expression of a metabotropic glutamate receptor
    • Masu, M.; Tanabe, Y.; Tsuchida, K.; Shigemoto, R.; Nakanishi, S. Sequence and expression of a metabotropic glutamate receptor. Nature, 1991, 349 (6312), 760-765.
    • (1991) Nature , vol.349 , Issue.6312 , pp. 760-765
    • Masu, M.1    Tanabe, Y.2    Tsuchida, K.3    Shigemoto, R.4    Nakanishi, S.5
  • 5
    • 0026681594 scopus 로고
    • Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction
    • Abe, T.; Sugihara, H.; Nawa, H.; Shigemoto, R.; Mizuno, N.; Nakanishi, S. Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction. J. Biol. Chem., 1992, 267 (19), 13361-13368.
    • (1992) J. Biol. Chem. , vol.267 , Issue.19 , pp. 13361-13368
    • Abe, T.1    Sugihara, H.2    Nawa, H.3    Shigemoto, R.4    Mizuno, N.5    Nakanishi, S.6
  • 6
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • Kew, J. N.; Kemp, J. A. Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacology (Berl), 2005, 179 (1), 4-29.
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 4-29
    • Kew, J.N.1    Kemp, J.A.2
  • 7
    • 0026794813 scopus 로고
    • Cellular localization of a metabotropic glutamate receptor in rat brain
    • Martin, L. J.; Blackstone, C. D.; Huganir, R. L.; Price, D. L. Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron, 1992, 9 (2), 259-270.
    • (1992) Neuron , vol.9 , Issue.2 , pp. 259-270
    • Martin, L.J.1    Blackstone, C.D.2    Huganir, R.L.3    Price, D.L.4
  • 8
    • 0027475709 scopus 로고
    • Differential localization of phosphoinositide- linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain
    • Fotuhi, M.; Sharp, A. H.; Glatt, C. E.; Hwang, P. M.; von, K. M.; Snyder, S. H.; Dawson, T. M. Differential localization of phosphoinositide- linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain. J. Neurosci., 1993, 13 (5), 2001-2012.
    • (1993) J. Neurosci. , vol.13 , Issue.5 , pp. 2001-2012
    • Fotuhi, M.1    Sharp, A.H.2    Glatt, C.E.3    Hwang, P.M.4    Von, K.M.5    Snyder, S.H.6    Dawson, T.M.7
  • 9
    • 0030014918 scopus 로고    scopus 로고
    • Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus
    • Lujan, R.; Nusser, Z.; Roberts, J. D.; Shigemoto, R.; Somogyi, P. Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus. Eur. J. Neurosci., 1996, 8 (7), 1488-1500.
    • (1996) Eur. J. Neurosci. , vol.8 , Issue.7 , pp. 1488-1500
    • Lujan, R.1    Nusser, Z.2    Roberts, J.D.3    Shigemoto, R.4    Somogyi, P.5
  • 10
    • 0027378595 scopus 로고
    • Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
    • Shigemoto, R.; Nomura, S.; Ohishi, H.; Sugihara, H.; Nakanishi, S.; Mizuno, N. Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci. Lett., 1993, 163 (1), 53-57.
    • (1993) Neurosci. Lett. , vol.163 , Issue.1 , pp. 53-57
    • Shigemoto, R.1    Nomura, S.2    Ohishi, H.3    Sugihara, H.4    Nakanishi, S.5    Mizuno, N.6
  • 11
    • 13244264871 scopus 로고    scopus 로고
    • Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
    • Rodrigues, R. J.; Alfaro, T. M.; Rebola, N.; Oliveira, C. R.; Cunha, R. A. Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. J. Neurochem., 2005, 92 (3), 433-441.
    • (2005) J. Neurochem. , vol.92 , Issue.3 , pp. 433-441
    • Rodrigues, R.J.1    Alfaro, T.M.2    Rebola, N.3    Oliveira, C.R.4    Cunha, R.A.5
  • 13
    • 0030704241 scopus 로고    scopus 로고
    • Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites
    • Lujan, R.; Roberts, J. D.; Shigemoto, R.; Ohishi, H.; Somogyi, P. Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites. J. Chem. Neuroanat., 1997, 13 (4), 219-241.
    • (1997) J. Chem. Neuroanat. , vol.13 , Issue.4 , pp. 219-241
    • Lujan, R.1    Roberts, J.D.2    Shigemoto, R.3    Ohishi, H.4    Somogyi, P.5
  • 14
    • 33748924690 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors
    • Ferraguti, F.; Shigemoto, R. Metabotropic glutamate receptors. Cell Tissue Res., 2006, 326 (2), 483-504.
    • (2006) Cell Tissue Res , vol.326 , Issue.2 , pp. 483-504
    • Ferraguti, F.1    Shigemoto, R.2
  • 15
    • 0029874694 scopus 로고    scopus 로고
    • The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations
    • Petralia, R. S.; Wang, Y. X.; Niedzielski, A. S.; Wenthold, R. J. The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience, 1996, 71 (4), 949-976.
    • (1996) Neuroscience , vol.71 , Issue.4 , pp. 949-976
    • Petralia, R.S.1    Wang, Y.X.2    Niedzielski, A.S.3    Wenthold, R.J.4
  • 17
    • 0035960059 scopus 로고    scopus 로고
    • Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: Differential location relative to pre- and postsynaptic sites
    • Tamaru, Y.; Nomura, S.; Mizuno, N.; Shigemoto, R. Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites. Neuroscience, 2001, 106 (3), 481-503.
    • (2001) Neuroscience , vol.106 , Issue.3 , pp. 481-503
    • Tamaru, Y.1    Nomura, S.2    Mizuno, N.3    Shigemoto, R.4
  • 19
    • 0030045889 scopus 로고    scopus 로고
    • Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: An immunohistochemical study with a monoclonal antibody
    • Neki, A.; Ohishi, H.; Kaneko, T.; Shigemoto, R.; Nakanishi, S.; Mizuno, N. Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: an immunohistochemical study with a monoclonal antibody. Neurosci. Lett., 1996, 202 (3), 197-200.
    • (1996) Neurosci. Lett. , vol.202 , Issue.3 , pp. 197-200
    • Neki, A.1    Ohishi, H.2    Kaneko, T.3    Shigemoto, R.4    Nakanishi, S.5    Mizuno, N.6
  • 20
    • 0030561581 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum
    • Neki, A.; Ohishi, H.; Kaneko, T.; Shigemoto, R.; Nakanishi, S.; Mizuno, N. Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum. Neuroscience, 1996, 75 (3), 815-826.
    • (1996) Neuroscience , vol.75 , Issue.3 , pp. 815-826
    • Neki, A.1    Ohishi, H.2    Kaneko, T.3    Shigemoto, R.4    Nakanishi, S.5    Mizuno, N.6
  • 21
    • 0029120580 scopus 로고
    • Distributions of the mRNAs for L-2-amino-4-phosphonobutyratesensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain
    • Ohishi, H.; Akazawa, C.; Shigemoto, R.; Nakanishi, S.; Mizuno, N. Distributions of the mRNAs for L-2-amino-4-phosphonobutyratesensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain. J. Comp. Neurol., 1995, 360 (4), 555-570.
    • (1995) J. Comp. Neurol. , vol.360 , Issue.4 , pp. 555-570
    • Ohishi, H.1    Akazawa, C.2    Shigemoto, R.3    Nakanishi, S.4    Mizuno, N.5
  • 22
    • 0028088017 scopus 로고
    • Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex
    • Ohishi, H.; Ogawa-Meguro, R.; Shigemoto, R.; Kaneko, T.; Nakanishi, S.; Mizuno, N. Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex. Neuron, 1994, 13 (1), 55-66.
    • (1994) Neuron , vol.13 , Issue.1 , pp. 55-66
    • Ohishi, H.1    Ogawa-Meguro, R.2    Shigemoto, R.3    Kaneko, T.4    Nakanishi, S.5    Mizuno, N.6
  • 23
    • 0027232329 scopus 로고
    • Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate
    • Nakajima, Y.; Iwakabe, H.; Akazawa, C.; Nawa, H.; Shigemoto, R.; Mizuno, N.; Nakanishi, S. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem., 1993, 268 (16), 11868-11873.
    • (1993) J. Biol. Chem. , vol.268 , Issue.16 , pp. 11868-11873
    • Nakajima, Y.1    Iwakabe, H.2    Akazawa, C.3    Nawa, H.4    Shigemoto, R.5    Mizuno, N.6    Nakanishi, S.7
  • 24
    • 0027772108 scopus 로고
    • Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii
    • Glaum, S. R.; Miller, R. J. Metabotropic glutamate receptors depress afferent excitatory transmission in the rat nucleus tractus solitarii. J. Neurophysiol., 1993, 70 (6), 2669-2672.
    • (1993) J. Neurophysiol. , vol.70 , Issue.6 , pp. 2669-2672
    • Glaum, S.R.1    Miller, R.J.2
  • 25
    • 0036716723 scopus 로고    scopus 로고
    • Enrichment of mGluR7a in the presynaptic active zones of GABAergic and non-GABAergic terminals on interneurons in the rat somatosensory cortex
    • Dalezios, Y.; Lujan, R.; Shigemoto, R.; Roberts, J. D.; Somogyi, P. Enrichment of mGluR7a in the presynaptic active zones of GABAergic and non-GABAergic terminals on interneurons in the rat somatosensory cortex. Cereb. Cortex, 2002, 12 (9), 961-974.
    • (2002) Cereb. Cortex. , vol.12 , Issue.9 , pp. 961-974
    • Dalezios, Y.1    Lujan, R.2    Shigemoto, R.3    Roberts, J.D.4    Somogyi, P.5
  • 26
    • 0038684774 scopus 로고    scopus 로고
    • High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus
    • Somogyi, P.; Dalezios, Y.; Lujan, R.; Roberts, J. D.; Watanabe, M.; Shigemoto, R. High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus. Eur. J. Neurosci., 2003, 17 (12), 2503-2520.
    • (2003) Eur. J. Neurosci. , vol.17 , Issue.12 , pp. 2503-2520
    • Somogyi, P.1    Dalezios, Y.2    Lujan, R.3    Roberts, J.D.4    Watanabe, M.5    Shigemoto, R.6
  • 28
    • 0033538893 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn
    • Jia, H.; Rustioni, A.; Valtschanoff, J. G. Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn. J. Comp. Neurol., 1999, 410 (4), 627-642.
    • (1999) J. Comp. Neurol. , vol.410 , Issue.4 , pp. 627-642
    • Jia, H.1    Rustioni, A.2    Valtschanoff, J.G.3
  • 29
    • 0029090582 scopus 로고
    • Distribution of metabotropic glutamate receptor 7 messenger RNA in the developing and adult rat brain
    • Kinzie, J. M.; Saugstad, J. A.; Westbrook, G. L.; Segerson, T. P. Distribution of metabotropic glutamate receptor 7 messenger RNA in the developing and adult rat brain. Neuroscience, 1995, 69 (1), 167-176.
    • (1995) Neuroscience , vol.69 , Issue.1 , pp. 167-176
    • Kinzie, J.M.1    Saugstad, J.A.2    Westbrook, G.L.3    Segerson, T.P.4
  • 30
    • 0031050960 scopus 로고    scopus 로고
    • Localization of a metabotropic glutamate receptor, mGluR7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: An electron microscope study in the rat
    • Li, H.; Ohishi, H.; Kinoshita, A.; Shigemoto, R.; Nomura, S.; Mizuno, N. Localization of a metabotropic glutamate receptor, mGluR7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: an electron microscope study in the rat. Neurosci. Lett., 1997, 223 (3), 153-156.
    • (1997) Neurosci. Lett. , vol.223 , Issue.3 , pp. 153-156
    • Li, H.1    Ohishi, H.2    Kinoshita, A.3    Shigemoto, R.4    Nomura, S.5    Mizuno, N.6
  • 31
    • 0029566973 scopus 로고
    • Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: An immunohistochemical study in the rat
    • Ohishi, H.; Nomura, S.; Ding, Y. Q.; Shigemoto, R.; Wada, E.; Kinoshita, A.; Li, J. L.; Neki, A.; Nakanishi, S.; Mizuno, N. Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: an immunohistochemical study in the rat. Neurosci. Lett., 1995, 202 (1-2), 85-88.
    • (1995) Neurosci. Lett. , vol.202 , Issue.1-2 , pp. 85-88
    • Ohishi, H.1    Nomura, S.2    Ding, Y.Q.3    Shigemoto, R.4    Wada, E.5    Kinoshita, A.6    Li, J.L.7    Neki, A.8    Nakanishi, S.9    Mizuno, N.10
  • 32
    • 0035094199 scopus 로고    scopus 로고
    • Peripheral group I metabotropic glutamate receptors modulate nociception in mice
    • Bhave, G.; Karim, F.; Carlton, S. M.; Gereau, R. W. Peripheral group I metabotropic glutamate receptors modulate nociception in mice. Nat. Neurosci., 2001, 4 (4), 417-423.
    • (2001) Nat. Neurosci. , vol.4 , Issue.4 , pp. 417-423
    • Bhave, G.1    Karim, F.2    Carlton, S.M.3    Gereau, R.W.4
  • 33
    • 33847331085 scopus 로고    scopus 로고
    • Colocalization of metabotropic glutamate receptors in rat dorsal root ganglion cells
    • Carlton, S. M.; Hargett, G. L. Colocalization of metabotropic glutamate receptors in rat dorsal root ganglion cells. J. Comp. Neurol., 2007, 501 (5), 780-789.
    • (2007) J. Comp. Neurol. , vol.501 , Issue.5 , pp. 780-789
    • Carlton, S.M.1    Hargett, G.L.2
  • 34
    • 0033763535 scopus 로고    scopus 로고
    • mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia
    • Walker, K.; Reeve, A.; Bowes, M.; Winter, J.; Wotherspoon, G.; Davis, A.; Schmid, P.; Gasparini, F.; Kuhn, R.; Urban, L. mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia. Neuropharmacology, 2001, 40 (1), 10-19.
    • (2001) Neuropharmacology , vol.40 , Issue.1 , pp. 10-19
    • Walker, K.1    Reeve, A.2    Bowes, M.3    Winter, J.4    Wotherspoon, G.5    Davis, A.6    Schmid, P.7    Gasparini, F.8    Kuhn, R.9    Urban, L.10
  • 35
    • 15244350494 scopus 로고    scopus 로고
    • Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand
    • Taylor, D. L.; Jones, F.; Kubota, E. S.; Pocock, J. M. Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. J. Neurosci., 2005, 25 (11), 2952-2964.
    • (2005) J. Neurosci. , vol.25 , Issue.11 , pp. 2952-2964
    • Taylor, D.L.1    Jones, F.2    Kubota, E.S.3    Pocock, J.M.4
  • 36
    • 0036724311 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease
    • Taylor, D. L.; Diemel, L. T.; Cuzner, M. L.; Pocock, J. M. Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease. J. Neurochem. 2002, 82 (5), 1179-1191.
    • (2002) J. Neurochem. , vol.82 , Issue.5 , pp. 1179-1191
    • Taylor, D.L.1    Diemel, L.T.2    Cuzner, M.L.3    Pocock, J.M.4
  • 37
    • 2442677876 scopus 로고    scopus 로고
    • Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress
    • Deng, W.; Wang, H.; Rosenberg, P. A.; Volpe, J. J.; Jensen, F. E. Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress. Proc. Natl. Acad. Sci. USA, 2004, 101 (20), 7751-7756.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.20 , pp. 7751-7756
    • Deng, W.1    Wang, H.2    Rosenberg, P.A.3    Volpe, J.J.4    Jensen, F.E.5
  • 38
    • 0035824570 scopus 로고    scopus 로고
    • Alpha 1-adrenergic modulation of metabotropic glutamate receptor-induced calcium oscillations and glutamate release in astrocytes
    • Muyderman, H.; Angehagen, M.; Sandberg, M.; Bjorklund, U.; Olsson, T.; Hansson, E.; Nilsson, M. Alpha 1-adrenergic modulation of metabotropic glutamate receptor-induced calcium oscillations and glutamate release in astrocytes. J. Biol. Chem., 2001, 276 (49), 46504-46514.
    • (2001) J. Biol. Chem. , vol.276 , Issue.49 , pp. 46504-46514
    • Muyderman, H.1    Angehagen, M.2    Sandberg, M.3    Bjorklund, U.4    Olsson, T.5    Hansson, E.6    Nilsson, M.7
  • 39
    • 0038810014 scopus 로고    scopus 로고
    • Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: Opposite regulation of glutamate transporter proteins
    • Aronica, E.; Gorter, J. A.; Ijlst-Keizers, H.; Rozemuller, A. J.; Yankaya, B.; Leenstra, S.; Troost, D. Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins. Eur. J. Neurosci., 2003, 17 (10), 2106-2118.
    • (2003) Eur. J. Neurosci. , vol.17 , Issue.10 , pp. 2106-2118
    • Aronica, E.1    Gorter, J.A.2    Ijlst-Keizers, H.3    Rozemuller, A.J.4    Yankaya, B.5    Leenstra, S.6    Troost, D.7
  • 40
    • 11844269229 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 3 enhances interleukin (IL)-1beta-stimulated release of IL-6 in cultured human astrocytes
    • Aronica, E.; Gorter, J. A.; Rozemuller, A. J.; Yankaya, B.; Troost, D. Activation of metabotropic glutamate receptor 3 enhances interleukin (IL)-1beta-stimulated release of IL-6 in cultured human astrocytes. Neuroscience, 2005, 130 (4), 927-933.
    • (2005) Neuroscience , vol.130 , Issue.4 , pp. 927-933
    • Aronica, E.1    Gorter, J.A.2    Rozemuller, A.J.3    Yankaya, B.4    Troost, D.5
  • 41
    • 0026635029 scopus 로고
    • Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract
    • Glaum, S. R.; Miller, R. J. Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract. J. Neurosci., 1992, 12 (6), 2251-2258.
    • (1992) J. Neurosci. , vol.12 , Issue.6 , pp. 2251-2258
    • Glaum, S.R.1    Miller, R.J.2
  • 42
    • 0032907608 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Electrophysiological properties and role in plasticity
    • Anwyl, R. Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res. Brain Res. Rev., 1999, 29 (1), 83-120.
    • (1999) Brain Res. Brain Res. Rev. , vol.29 , Issue.1 , pp. 83-120
    • Anwyl, R.1
  • 43
    • 44949104175 scopus 로고    scopus 로고
    • Presynaptic glutamate receptors: Physiological functions and mechanisms of action
    • Pinheiro, P. S.; Mulle, C. Presynaptic glutamate receptors: physiological functions and mechanisms of action. Nat. Rev. Neurosci., 2008, 9 (6), 423-436.
    • (2008) Nat. Rev. Neurosci. , vol.9 , Issue.6 , pp. 423-436
    • Pinheiro, P.S.1    Mulle, C.2
  • 44
    • 0025952198 scopus 로고
    • An ion channel locus for the protein kinase C potentiation of transmitter glutamate release from guinea pig cerebrocortical synaptosomes
    • Barrie, A. P.; Nicholls, D. G.; Sanchez-Prieto, J.; Sihra, T. S. An ion channel locus for the protein kinase C potentiation of transmitter glutamate release from guinea pig cerebrocortical synaptosomes. J. Neurochem., 1991, 57 (4), 1398-1404.
    • (1991) J. Neurochem. , vol.57 , Issue.4 , pp. 1398-1404
    • Barrie, A.P.1    Nicholls, D.G.2    Sanchez-Prieto, J.3    Sihra, T.S.4
  • 45
    • 0028102254 scopus 로고
    • Glutamate exocytosis and MARCKS phosphorylation are enhanced by a metabotropic glutamate receptor coupled to a protein kinase C synergistically activated by diacylglycerol and arachidonic acid
    • Coffey, E. T.; Herrero, I.; Sihra, T. S.; Sanchez-Prieto, J.; Nicholls, D. G. Glutamate exocytosis and MARCKS phosphorylation are enhanced by a metabotropic glutamate receptor coupled to a protein kinase C synergistically activated by diacylglycerol and arachidonic acid. J. Neurochem., 1994, 63 (4), 1303-1310.
    • (1994) J. Neurochem. , vol.63 , Issue.4 , pp. 1303-1310
    • Coffey, E.T.1    Herrero, I.2    Sihra, T.S.3    Sanchez-Prieto, J.4    Nicholls, D.G.5
  • 46
    • 2442691555 scopus 로고    scopus 로고
    • Noncompetitive metabotropic glutamate5 receptor antagonist (E)-2-methyl-6-styryl-pyridine (SIB1893) depresses glutamate release through inhibition of voltage-dependent Ca2+ entry in rat cerebrocortical nerve terminals (synaptosomes)
    • Wang, S. J.; Sihra, T. S. Noncompetitive metabotropic glutamate5 receptor antagonist (E)-2-methyl-6-styryl-pyridine (SIB1893) depresses glutamate release through inhibition of voltage-dependent Ca2+ entry in rat cerebrocortical nerve terminals (synaptosomes). J. Pharmacol. Exp. Ther., 2004, 309 (3), 951-958.
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , Issue.3 , pp. 951-958
    • Wang, S.J.1    Sihra, T.S.2
  • 47
    • 6344257091 scopus 로고    scopus 로고
    • Dual signaling by mGluR5a results in bi-directional modulation of N-type Ca2+ channels
    • Sanchez-Prieto, J.; Paternain, A. V.; Lerma, J. Dual signaling by mGluR5a results in bi-directional modulation of N-type Ca2+ channels. FEBS Lett., 2004, 576 (3), 428-432.
    • (2004) FEBS Lett , vol.576 , Issue.3 , pp. 428-432
    • Sanchez-Prieto, J.1    Paternain, A.V.2    Lerma, J.3
  • 48
    • 0035053627 scopus 로고    scopus 로고
    • Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
    • Kreitzer, A. C.; Regehr, W. G. Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron, 2001, 29 (3), 717-727.
    • (2001) Neuron , vol.29 , Issue.3 , pp. 717-727
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 49
    • 33750495376 scopus 로고    scopus 로고
    • Compartmentalized Ca(2+) channel regulation at divergent mossy-fiber release sites underlies target cell-dependent plasticity
    • Pelkey, K. A.; Topolnik, L.; Lacaille, J. C.; McBain, C. J. Compartmentalized Ca(2+) channel regulation at divergent mossy-fiber release sites underlies target cell-dependent plasticity. Neuron, 2006, 52 (3), 497-510.
    • (2006) Neuron , vol.52 , Issue.3 , pp. 497-510
    • Pelkey, K.A.1    Topolnik, L.2    Lacaille, J.C.3    McBain, C.J.4
  • 50
    • 0036616837 scopus 로고    scopus 로고
    • Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3- dependent presynaptic long-term depression at nucleus accumbens synapses
    • Robbe, D.; Alonso, G.; Chaumont, S.; Bockaert, J.; Manzoni, O. J. Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3- dependent presynaptic long-term depression at nucleus accumbens synapses. J. Neurosci., 2002, 22 (11), 4346-4356.
    • (2002) J. Neurosci. , vol.22 , Issue.11 , pp. 4346-4356
    • Robbe, D.1    Alonso, G.2    Chaumont, S.3    Bockaert, J.4    Manzoni, O.J.5
  • 52
    • 16844380129 scopus 로고    scopus 로고
    • mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition
    • Pelkey, K. A.; Lavezzari, G.; Racca, C.; Roche, K. W.; McBain, C. J. mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition. Neuron, 2005, 46 (1), 89-102.
    • (2005) Neuron , vol.46 , Issue.1 , pp. 89-102
    • Pelkey, K.A.1    Lavezzari, G.2    Racca, C.3    Roche, K.W.4    McBain, C.J.5
  • 53
    • 0034330981 scopus 로고    scopus 로고
    • Selective blockade of P/Q-type calcium channels by the metabotropic glutamate receptor type 7 involves a phospholipase C pathway in neurons
    • Perroy, J.; Prezeau, L.; De, W. M.; Shigemoto, R.; Bockaert, J.; Fagni, L. Selective blockade of P/Q-type calcium channels by the metabotropic glutamate receptor type 7 involves a phospholipase C pathway in neurons. J. Neurosci., 2000, 20 (21), 7896-7904.
    • (2000) J. Neurosci. , vol.20 , Issue.21 , pp. 7896-7904
    • Perroy, J.1    Prezeau, L.2    De, W.M.3    Shigemoto, R.4    Bockaert, J.5    Fagni, L.6
  • 54
    • 0035853270 scopus 로고    scopus 로고
    • G protein betagamma subunit-mediated presynaptic inhibition: Regulation of exocytotic fusion downstream of Ca2+ entry
    • Blackmer, T.; Larsen, E. C.; Takahashi, M.; Martin, T. F.; Alford, S.; Hamm, H. E. G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of Ca2+ entry. Science, 2001, 292 (5515), 293-297.
    • (2001) Science , vol.292 , Issue.5515 , pp. 293-297
    • Blackmer, T.1    Larsen, E.C.2    Takahashi, M.3    Martin, T.F.4    Alford, S.5    Hamm, H.E.6
  • 56
  • 57
    • 36549053560 scopus 로고    scopus 로고
    • Noradrenaline modulates transmission at a central synapse by a presynaptic mechanism
    • Delaney, A. J.; Crane, J. W.; Sah, P. Noradrenaline modulates transmission at a central synapse by a presynaptic mechanism. Neuron, 2007, 56 (5), 880-892.
    • (2007) Neuron , vol.56 , Issue.5 , pp. 880-892
    • Delaney, A.J.1    Crane, J.W.2    Sah, P.3
  • 58
    • 0027166147 scopus 로고
    • Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus
    • Bashir, Z. I.; Jane, D. E.; Sunter, D. C.; Watkins, J. C.; Collingridge, G. L. Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus. Eur. J. Pharmacol., 1993, 239 (1-3), 265-266.
    • (1993) Eur. J. Pharmacol. , vol.239 , Issue.1-3 , pp. 265-266
    • Bashir, Z.I.1    Jane, D.E.2    Sunter, D.C.3    Watkins, J.C.4    Collingridge, G.L.5
  • 59
    • 0028244082 scopus 로고
    • Postsynaptic induction and presynaptic expression of hippocampal long-term depression
    • Bolshakov, V. Y.; Siegelbaum, S. A. Postsynaptic induction and presynaptic expression of hippocampal long-term depression. Science, 1994, 264 (5162), 1148-1152.
    • (1994) Science , vol.264 , Issue.5162 , pp. 1148-1152
    • Bolshakov, V.Y.1    Siegelbaum, S.A.2
  • 60
    • 0032870419 scopus 로고    scopus 로고
    • DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterisation and sensitivity to novel mGlu receptor antagonists
    • Fitzjohn, S. M.; Kingston, A. E.; Lodge, D.; Collingridge, G. L. DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterisation and sensitivity to novel mGlu receptor antagonists. Neuropharmacology, 1999, 38 (10), 1577-1583.
    • (1999) Neuropharmacology , vol.38 , Issue.10 , pp. 1577-1583
    • Fitzjohn, S.M.1    Kingston, A.E.2    Lodge, D.3    Collingridge, G.L.4
  • 61
    • 0032985245 scopus 로고    scopus 로고
    • Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors
    • Kemp, N.; Bashir, Z. I. Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors. Neuropharmacology, 1999, 38 (4), 495-504.
    • (1999) Neuropharmacology , vol.38 , Issue.4 , pp. 495-504
    • Kemp, N.1    Bashir, Z.I.2
  • 62
    • 0029099597 scopus 로고
    • Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro
    • O'Mara, S. M.; Rowan, M. J.; Anwyl, R. Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro. Neuropharmacology, 1995, 34 (8), 983-989.
    • (1995) Neuropharmacology , vol.34 , Issue.8 , pp. 983-989
    • O'Mara, S.M.1    Rowan, M.J.2    Anwyl, R.3
  • 63
    • 0031406039 scopus 로고    scopus 로고
    • The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus
    • Palmer, M. J.; Irving, A. J.; Seabrook, G. R.; Jane, D. E.; Collingridge, G. L. The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus. Neuropharmacology, 1997, 36 (11-12), 1517-1532.
    • (1997) Neuropharmacology , vol.36 , Issue.11-12 , pp. 1517-1532
    • Palmer, M.J.1    Irving, A.J.2    Seabrook, G.R.3    Jane, D.E.4    Collingridge, G.L.5
  • 64
    • 48049101169 scopus 로고    scopus 로고
    • Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro
    • Wang, W.; Zhang, Z.; Shang, J.; Jiang, Z. Z.; Wang, S.; Liu, Y.; Zhang, L. Y. Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro. Neurosci. Res., 2008, 62 (1), 43-50.
    • (2008) Neurosci. Res. , vol.62 , Issue.1 , pp. 43-50
    • Wang, W.1    Zhang, Z.2    Shang, J.3    Jiang, Z.Z.4    Wang, S.5    Liu, Y.6    Zhang, L.Y.7
  • 66
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • Malenka, R. C.; Bear, M. F. LTP and LTD: an embarrassment of riches. Neuron, 2004, 44 (1), 5-21.
    • (2004) Neuron , vol.44 , Issue.1 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 67
    • 0029780982 scopus 로고    scopus 로고
    • Presynaptic long-term depression at the hippocampal mossy fiber-CA3 synapse
    • Kobayashi, K.; Manabe, T.; Takahashi, T. Presynaptic long-term depression at the hippocampal mossy fiber-CA3 synapse. Science, 1996, 273 (5275), 648-650.
    • (1996) Science , vol.273 , Issue.5275 , pp. 648-650
    • Kobayashi, K.1    Manabe, T.2    Takahashi, T.3
  • 69
    • 0035370861 scopus 로고    scopus 로고
    • Time-dependent reversal of long-term potentiation by low-frequency stimulation at the hippocampal mossy fiber-CA3 synapses
    • Chen, Y. L.; Huang, C. C.; Hsu, K. S. Time-dependent reversal of long-term potentiation by low-frequency stimulation at the hippocampal mossy fiber-CA3 synapses. J. Neurosci., 2001, 21 (11), 3705-3714.
    • (2001) J. Neurosci. , vol.21 , Issue.11 , pp. 3705-3714
    • Chen, Y.L.1    Huang, C.C.2    Hsu, K.S.3
  • 70
    • 71249097446 scopus 로고    scopus 로고
    • Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala
    • Hong, I.; Song, B.; Lee, S.; Kim, J.; Kim, J.; Choi, S. Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala. Eur. J. Neurosci., 2009, 30 (11), 2089-2099.
    • (2009) Eur. J. Neurosci. , vol.30 , Issue.11 , pp. 2089-2099
    • Hong, I.1    Song, B.2    Lee, S.3    Kim, J.4    Kim, J.5    Choi, S.6
  • 71
    • 0033609981 scopus 로고    scopus 로고
    • Long-term depression in hippocampal interneurons: Joint requirement for pre- and postsynaptic events
    • Laezza, F.; Doherty, J. J.; Dingledine, R. Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events. Science, 1999, 285 (5432), 1411-1414.
    • (1999) Science , vol.285 , Issue.5432 , pp. 1411-1414
    • Laezza, F.1    Doherty, J.J.2    Dingledine, R.3
  • 72
    • 73449137227 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated long-term depression: Molecular mechanisms
    • Gladding, C. M.; Fitzjohn, S. M.; Molnar, E. Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms. Pharmacol. Rev., 2009, 61 (4), 395-412.
    • (2009) Pharmacol. Rev. , vol.61 , Issue.4 , pp. 395-412
    • Gladding, C.M.1    Fitzjohn, S.M.2    Molnar, E.3
  • 73
    • 60149095737 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-dependent long-term potentiation
    • Anwyl, R. Metabotropic glutamate receptor-dependent long-term potentiation. Neuropharmacology, 2009, 56 (4), 735-740.
    • (2009) Neuropharmacology , vol.56 , Issue.4 , pp. 735-740
    • Anwyl, R.1
  • 76
    • 37549021899 scopus 로고    scopus 로고
    • Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses
    • Rebola, N.; Lujan, R.; Cunha, R. A.; Mulle, C. Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses. Neuron, 2008, 57 (1), 121-134.
    • (2008) Neuron , vol.57 , Issue.1 , pp. 121-134
    • Rebola, N.1    Lujan, R.2    Cunha, R.A.3    Mulle, C.4
  • 77
    • 37549031345 scopus 로고    scopus 로고
    • Long-term potentiation selectively expressed by NMDA receptors at hippocampal mossy fiber synapses
    • Kwon, H. B.; Castillo, P. E. Long-term potentiation selectively expressed by NMDA receptors at hippocampal mossy fiber synapses. Neuron, 2008, 57 (1), 108-120.
    • (2008) Neuron , vol.57 , Issue.1 , pp. 108-120
    • Kwon, H.B.1    Castillo, P.E.2
  • 78
    • 23644434602 scopus 로고    scopus 로고
    • The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors
    • Bortolotto, Z. A.; Collett, V. J.; Conquet, F.; Jia, Z.; van der Putten, H.; Collingridge, G. L. The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors. Neuropharmacology, 2005, 49 Suppl 1, 13-25.
    • (2005) Neuropharmacology , vol.49 , Issue.SUPPL. 1 , pp. 13-25
    • Bortolotto, Z.A.1    Collett, V.J.2    Conquet, F.3    Jia, Z.4    van der Putten, H.5    Collingridge, G.L.6
  • 79
    • 0030954048 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
    • Lu, Y. M.; Jia, Z.; Janus, C.; Henderson, J. T.; Gerlai, R.; Wojtowicz, J. M.; Roder, J. C. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci., 1997, 17 (13), 5196-5205.
    • (1997) J. Neurosci. , vol.17 , Issue.13 , pp. 5196-5205
    • Lu, Y.M.1    Jia, Z.2    Janus, C.3    Henderson, J.T.4    Gerlai, R.5    Wojtowicz, J.M.6    Roder, J.C.7
  • 80
    • 0942290621 scopus 로고    scopus 로고
    • Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: Relevance for learning and memory formation
    • Naie, K.; Manahan-Vaughan, D. Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation. Cereb. Cortex, 2004, 14 (2), 189-198.
    • (2004) Cereb. Cortex. , vol.14 , Issue.2 , pp. 189-198
    • Naie, K.1    Manahan-Vaughan, D.2
  • 82
    • 0028864442 scopus 로고
    • Metabotropic glutamate receptor antagonist, (R,S)-alpha-methyl-4-carboxyphenyglycine, blocks two distinct forms of long-term potentiation in area CA1 of rat hippocampus
    • Little, Z.; Grover, L. M.; Teyler, T. J. Metabotropic glutamate receptor antagonist, (R,S)-alpha-methyl-4-carboxyphenyglycine, blocks two distinct forms of long-term potentiation in area CA1 of rat hippocampus. Neurosci. Lett., 1995, 201 (1), 73-76.
    • (1995) Neurosci. Lett. , vol.201 , Issue.1 , pp. 73-76
    • Little, Z.1    Grover, L.M.2    Teyler, T.J.3
  • 83
    • 0030657948 scopus 로고    scopus 로고
    • LTP induction dependent on activation of Ni2+-sensitive voltage-gated calcium channels, but not NMDA receptors, in the rat dentate gyrus in vitro
    • Wang, Y.; Rowan, M. J.; Anwyl, R. LTP induction dependent on activation of Ni2+-sensitive voltage-gated calcium channels, but not NMDA receptors, in the rat dentate gyrus in vitro. J. Neurophysiol., 1997, 78 (5), 2574-2581.
    • (1997) J. Neurophysiol. , vol.78 , Issue.5 , pp. 2574-2581
    • Wang, Y.1    Rowan, M.J.2    Anwyl, R.3
  • 84
    • 33744456766 scopus 로고    scopus 로고
    • Low-frequency stimulation induces a new form of LTP, metabotropic glutamate (mGlu5) receptor- and PKA-dependent, in the CA1 area of the rat hippocampus
    • Lante, F.; de Jesus Ferreira, M. C.; Guiramand, J.; Recasens, M.; Vignes, M. Low-frequency stimulation induces a new form of LTP, metabotropic glutamate (mGlu5) receptor- and PKA-dependent, in the CA1 area of the rat hippocampus. Hippocampus, 2006, 16 (4), 345-360.
    • (2006) Hippocampus , vol.16 , Issue.4 , pp. 345-360
    • Lante, F.1    de Jesus Ferreira, M.C.2    Guiramand, J.3    Recasens, M.4    Vignes, M.5
  • 85
    • 15244346364 scopus 로고    scopus 로고
    • Characterization of longterm potentiation of primary afferent transmission at trigeminal synapses of juvenile rats: Essential role of subtype 5 metabotropic glutamate receptors
    • Liang, Y. C.; Huang, C. C.; Hsu, K. S. Characterization of longterm potentiation of primary afferent transmission at trigeminal synapses of juvenile rats: essential role of subtype 5 metabotropic glutamate receptors. Pain, 2005, 114 (3), 417-428.
    • (2005) Pain , vol.114 , Issue.3 , pp. 417-428
    • Liang, Y.C.1    Huang, C.C.2    Hsu, K.S.3
  • 87
    • 0033401643 scopus 로고    scopus 로고
    • Evidence for involvement of group II/III metabotropic glutamate receptors in NMDA receptor-independent long-term potentiation in area CA1 of rat hippocampus
    • Grover, L. M.; Yan, C. Evidence for involvement of group II/III metabotropic glutamate receptors in NMDA receptor-independent long-term potentiation in area CA1 of rat hippocampus. J. Neurophysiol., 1999, 82 (6), 2956-2969.
    • (1999) J. Neurophysiol. , vol.82 , Issue.6 , pp. 2956-2969
    • Grover, L.M.1    Yan, C.2
  • 88
    • 0037101631 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor (mGluR)-dependent long-term depression mediated via p38 mitogen-activated protein kinase is inhibited by previous high-frequency stimulation and activation of mGluRs and protein kinase C in the rat dentate gyrus in vitro
    • Rush, A. M.; Wu, J.; Rowan, M. J.; Anwyl, R. Group I metabotropic glutamate receptor (mGluR)-dependent long-term depression mediated via p38 mitogen-activated protein kinase is inhibited by previous high-frequency stimulation and activation of mGluRs and protein kinase C in the rat dentate gyrus in vitro. J. Neurosci., 2002, 22 (14), 6121-6128.
    • (2002) J. Neurosci. , vol.22 , Issue.14 , pp. 6121-6128
    • Rush, A.M.1    Wu, J.2    Rowan, M.J.3    Anwyl, R.4
  • 89
    • 2942648152 scopus 로고    scopus 로고
    • Schizophrenia
    • Mueser, K. T.; McGurk, S. R. Schizophrenia. Lancet, 2004, 363 (9426), 2063-2072.
    • (2004) Lancet , vol.363 , Issue.9426 , pp. 2063-2072
    • Mueser, K.T.1    McGurk, S.R.2
  • 90
    • 34748864737 scopus 로고    scopus 로고
    • The pipeline and future of drug development in schizophrenia
    • Gray, J. A.; Roth, B. L. The pipeline and future of drug development in schizophrenia. Mol. Psychiatry, 2007, 12 (10), 904-922.
    • (2007) Mol. Psychiatry. , vol.12 , Issue.10 , pp. 904-922
    • Gray, J.A.1    Roth, B.L.2
  • 91
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman, P. Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse 1987, 1 (2), 133-152.
    • (1987) Synapse , vol.1 , Issue.2 , pp. 133-152
    • Seeman, P.1
  • 92
    • 6044278223 scopus 로고    scopus 로고
    • Receptor mechanisms in the treatment of schizophrenia
    • Reynolds, G. P. Receptor mechanisms in the treatment of schizophrenia. J. Psychopharmacol., 2004, 18 (3), 340-345.
    • (2004) J. Psychopharmacol. , vol.18 , Issue.3 , pp. 340-345
    • Reynolds, G.P.1
  • 93
    • 33749645423 scopus 로고    scopus 로고
    • Cognitive dysfunction in schizophrenia: Convergence of gamma-aminobutyric acid and glutamate alterations
    • Lewis, D. A.; Moghaddam, B. Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations. Arch. Neurol., 2006, 63 (10), 1372-1376.
    • (2006) Arch. Neurol. , vol.63 , Issue.10 , pp. 1372-1376
    • Lewis, D.A.1    Moghaddam, B.2
  • 94
    • 70350128123 scopus 로고    scopus 로고
    • Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: Therapeutic implications
    • Gaspar, P. A.; Bustamante, M. L.; Silva, H.; Aboitiz, F. Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: therapeutic implications. J. Neurochem., 2009, 111 (4), 891-900.
    • (2009) J. Neurochem. , vol.111 , Issue.4 , pp. 891-900
    • Gaspar, P.A.1    Bustamante, M.L.2    Silva, H.3    Aboitiz, F.4
  • 95
  • 97
    • 22544449233 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia
    • Gupta, D. S.; McCullumsmith, R. E.; Beneyto, M.; Haroutunian, V.; Davis, K. L.; Meador-Woodruff, J. H. Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse, 2005, 57 (3), 123-131.
    • (2005) Synapse , vol.57 , Issue.3 , pp. 123-131
    • Gupta, D.S.1    McCullumsmith, R.E.2    Beneyto, M.3    Haroutunian, V.4    Davis, K.L.5    Meador-Woodruff, J.H.6
  • 98
    • 0347419233 scopus 로고    scopus 로고
    • Disruption of prepulse inhibition in mice lacking mGluR1
    • Brody, S. A.; Conquet, F.; Geyer, M. A. Disruption of prepulse inhibition in mice lacking mGluR1. Eur. J. Neurosci., 2003, 18 (12), 3361-3366.
    • (2003) Eur. J. Neurosci. , vol.18 , Issue.12 , pp. 3361-3366
    • Brody, S.A.1    Conquet, F.2    Geyer, M.A.3
  • 99
    • 21344470129 scopus 로고    scopus 로고
    • mGluR5, but not mGluR1, antagonist modifies MK- 801-induced locomotor activity and deficit of prepulse inhibition
    • Pietraszek, M.; Gravius, A.; Schafer, D.; Weil, T.; Trifanova, D.; Danysz, W. mGluR5, but not mGluR1, antagonist modifies MK- 801-induced locomotor activity and deficit of prepulse inhibition. Neuropharmacology, 2005, 49 (1), 73-85.
    • (2005) Neuropharmacology , vol.49 , Issue.1 , pp. 73-85
    • Pietraszek, M.1    Gravius, A.2    Schafer, D.3    Weil, T.4    Trifanova, D.5    Danysz, W.6
  • 100
    • 0035124349 scopus 로고    scopus 로고
    • Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges
    • Attucci, S.; Carla, V.; Mannaioni, G.; Moroni, F. Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges. Br. J. Pharmacol., 2001, 132 (4), 799-806.
    • (2001) Br. J. Pharmacol. , vol.132 , Issue.4 , pp. 799-806
    • Attucci, S.1    Carla, V.2    Mannaioni, G.3    Moroni, F.4
  • 101
    • 61949104116 scopus 로고    scopus 로고
    • Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: Association with N-methyl-D-aspartic acid receptor up-regulation
    • Gray, L.; van den, B. M.; Scarr, E.; Dean, B.; Hannan, A. J. Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation. Int. J. Neuropsychopharmacol., 2009, 12 (1), 45-60.
    • (2009) Int. J. Neuropsychopharmacol. , vol.12 , Issue.1 , pp. 45-60
    • Gray, L.1    van den, B.M.2    Scarr, E.3    Dean, B.4    Hannan, A.J.5
  • 102
    • 2942650911 scopus 로고    scopus 로고
    • Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release
    • Homayoun, H.; Stefani, M. R.; Adams, B. W.; Tamagan, G. D.; Moghaddam, B. Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release. Neuropsychopharmacology, 2004, 29 (7), 1259-1269.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.7 , pp. 1259-1269
    • Homayoun, H.1    Stefani, M.R.2    Adams, B.W.3    Tamagan, G.D.4    Moghaddam, B.5
  • 105
    • 0037123728 scopus 로고    scopus 로고
    • Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors
    • Diaz-Cabiale, Z.; Vivo, M.; Del, A. A.; O'Connor, W. T.; Harte, M. K.; Muller, C. E.; Martinez, E.; Popoli, P.; Fuxe, K.; Ferre, S. Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors. Neurosci. Lett., 2002, 324 (2), 154-158.
    • (2002) Neurosci. Lett. , vol.324 , Issue.2 , pp. 154-158
    • Diaz-Cabiale, Z.1    Vivo, M.2    Del, A.A.3    O'Connor, W.T.4    Harte, M.K.5    Muller, C.E.6    Martinez, E.7    Popoli, P.8    Fuxe, K.9    Ferre, S.10
  • 106
    • 43449131567 scopus 로고    scopus 로고
    • Interaction of Nmethyl- D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm
    • Darrah, J. M.; Stefani, M. R.; Moghaddam, B. Interaction of Nmethyl- D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm. Behav. Pharmacol., 2008, 19 (3), 225-234.
    • (2008) Behav. Pharmacol. , vol.19 , Issue.3 , pp. 225-234
    • Darrah, J.M.1    Stefani, M.R.2    Moghaddam, B.3
  • 107
    • 28644440123 scopus 로고    scopus 로고
    • Bursting of prefrontal cortex neurons in awake rats is regulated by metabotropic glutamate 5 (mGlu5) receptors: Rate-dependent influence and interaction with NMDA receptors
    • Homayoun, H.; Moghaddam, B. Bursting of prefrontal cortex neurons in awake rats is regulated by metabotropic glutamate 5 (mGlu5) receptors: rate-dependent influence and interaction with NMDA receptors. Cereb. Cortex, 2006, 16 (1), 93-105.
    • (2006) Cereb. Cortex. , vol.16 , Issue.1 , pp. 93-105
    • Homayoun, H.1    Moghaddam, B.2
  • 108
    • 34548506012 scopus 로고    scopus 로고
    • Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonistinduced alteration of neuronal firing in prefrontal cortex
    • Lecourtier, L.; Homayoun, H.; Tamagnan, G.; Moghaddam, B. Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonistinduced alteration of neuronal firing in prefrontal cortex. Biol. Psychiatry 2007, 62 (7), 739-746.
    • (2007) Biol. Psychiatry. , vol.62 , Issue.7 , pp. 739-746
    • Lecourtier, L.1    Homayoun, H.2    Tamagnan, G.3    Moghaddam, B.4
  • 109
    • 33847026476 scopus 로고    scopus 로고
    • The selective mGlu5 receptor antagonist MTEP, similar to NMDA receptor antagonists, induces social isolation in rats
    • Koros, E.; Rosenbrock, H.; Birk, G.; Weiss, C.; Sams-Dodd, F. The selective mGlu5 receptor antagonist MTEP, similar to NMDA receptor antagonists, induces social isolation in rats. Neuropsychopharmacology, 2007, 32 (3), 562-576.
    • (2007) Neuropsychopharmacology , vol.32 , Issue.3 , pp. 562-576
    • Koros, E.1    Rosenbrock, H.2    Birk, G.3    Weiss, C.4    Sams-Dodd, F.5
  • 110
    • 0035056929 scopus 로고    scopus 로고
    • The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia
    • Devon, R. S.; Anderson, S.; Teague, P. W.; Muir, W. J.; Murray, V.; Pelosi, A. J.; Blackwood, D. H.; Porteous, D. J. The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Mol. Psychiatry, 2001, 6 (3), 311-314.
    • (2001) Mol. Psychiatry. , vol.6 , Issue.3 , pp. 311-314
    • Devon, R.S.1    Anderson, S.2    Teague, P.W.3    Muir, W.J.4    Murray, V.5    Pelosi, A.J.6    Blackwood, D.H.7    Porteous, D.J.8
  • 111
    • 0032078391 scopus 로고    scopus 로고
    • Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia
    • Ohnuma, T.; Augood, S. J.; Arai, H.; McKenna, P. J.; Emson, P. C. Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain. Res. Mol. Brain. Res., 1998, 56 (1-2), 207-217.
    • (1998) Brain. Res. Mol. Brain. Res. , vol.56 , Issue.1-2 , pp. 207-217
    • Ohnuma, T.1    Augood, S.J.2    Arai, H.3    McKenna, P.J.4    Emson, P.C.5
  • 112
    • 0030852182 scopus 로고    scopus 로고
    • In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats
    • Battaglia, G.; Monn, J. A.; Schoepp, D. D. In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats. Neurosci. Lett., 1997, 229 (3), 161-164.
    • (1997) Neurosci. Lett. , vol.229 , Issue.3 , pp. 161-164
    • Battaglia, G.1    Monn, J.A.2    Schoepp, D.D.3
  • 114
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
    • Moghaddam, B.; Adams, B. W. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science, 1998, 281 (5381), 1349-1352.
    • (1998) Science , vol.281 , Issue.5381 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2
  • 118
    • 33745227414 scopus 로고    scopus 로고
    • Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice
    • Galici, R.; Jones, C. K.; Hemstapat, K.; Nong, Y.; Echemendia, N. G.; Williams, L. C.; de, P. T.; Conn, P. J. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J. Pharmacol. Exp. Ther., 2006, 318 (1), 173-185.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , Issue.1 , pp. 173-185
    • Galici, R.1    Jones, C.K.2    Hemstapat, K.3    Nong, Y.4    Echemendia, N.G.5    Williams, L.C.6    De, P.T.7    Conn, P.J.8
  • 119
    • 45749139623 scopus 로고    scopus 로고
    • Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2- sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039)
    • Fell, M. J.; Svensson, K. A.; Johnson, B. G.; Schoepp, D. D. Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2- sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039). J. Pharmacol. Exp. Ther., 2008, 326 (1), 209-217.
    • (2008) J. Pharmacol. Exp. Ther. , vol.326 , Issue.1 , pp. 209-217
    • Fell, M.J.1    Svensson, K.A.2    Johnson, B.G.3    Schoepp, D.D.4
  • 120
    • 38949207272 scopus 로고    scopus 로고
    • The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity
    • Woolley, M. L.; Pemberton, D. J.; Bate, S.; Corti, C.; Jones, D. N. The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity. Psychopharmacology (Berl.,) 2008, 196 (3), 431-440.
    • (2008) Psychopharmacology (Berl.,) , vol.196 , Issue.3 , pp. 431-440
    • Woolley, M.L.1    Pemberton, D.J.2    Bate, S.3    Corti, C.4    Jones, D.N.5
  • 121
    • 34249888474 scopus 로고    scopus 로고
    • Stimulation of the metabotropic glutamate 2/3 receptor attenuates social novelty discrimination deficits induced by neonatal phencyclidine treatment
    • Harich, S.; Gross, G.; Bespalov, A. Stimulation of the metabotropic glutamate 2/3 receptor attenuates social novelty discrimination deficits induced by neonatal phencyclidine treatment. Psychopharmacology (Berl.,) 2007, 192 (4), 511-519.
    • (2007) Psychopharmacology (Berl.,) , vol.192 , Issue.4 , pp. 511-519
    • Harich, S.1    Gross, G.2    Bespalov, A.3
  • 122
    • 61449150536 scopus 로고    scopus 로고
    • Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition
    • Schlumberger, C.; Schafer, D.; Barberi, C.; More, L.; Nagel, J.; Pietraszek, M.; Schmidt, W. J.; Danysz, W. Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition. Behav. Pharmacol., 2009, 20 (1), 56-66.
    • (2009) Behav. Pharmacol. , vol.20 , Issue.1 , pp. 56-66
    • Schlumberger, C.1    Schafer, D.2    Barberi, C.3    More, L.4    Nagel, J.5    Pietraszek, M.6    Schmidt, W.J.7    Danysz, W.8
  • 123
    • 15544385061 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate 2/3 receptors reverses the effects of NMDA receptor hypofunction on prefrontal cortex unit activity in awake rats
    • Homayoun, H.; Jackson, M. E.; Moghaddam, B. Activation of metabotropic glutamate 2/3 receptors reverses the effects of NMDA receptor hypofunction on prefrontal cortex unit activity in awake rats. J. Neurophysiol., 2005, 93 (4), 1989-2001.
    • (2005) J. Neurophysiol. , vol.93 , Issue.4 , pp. 1989-2001
    • Homayoun, H.1    Jackson, M.E.2    Moghaddam, B.3
  • 124
    • 20944439080 scopus 로고    scopus 로고
    • Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects
    • Krystal, J. H.; bi-Saab, W.; Perry, E.; D'Souza, D. C.; Liu, N.; Gueorguieva, R.; McDougall, L.; Hunsberger, T.; Belger, A.; Levine, L.; Breier, A. Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects. Psychopharmacology (Berl), 2005, 179 (1), 303-309.
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 303-309
    • Krystal, J.H.1    Bi-Saab, W.2    Perry, E.3    D'Souza, D.C.4    Liu, N.5    Gueorguieva, R.6    McDougall, L.7    Hunsberger, T.8    Belger, A.9    Levine, L.10    Breier, A.11
  • 125
    • 53949094531 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia
    • Ghose, S.; Crook, J. M.; Bartus, C. L.; Sherman, T. G.; Herman, M. M.; Hyde, T. M.; Kleinman, J. E.; Akil, M. Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia. Int. J. Neurosci., 2008, 118 (11), 1609-1627.
    • (2008) Int. J. Neurosci. , vol.118 , Issue.11 , pp. 1609-1627
    • Ghose, S.1    Crook, J.M.2    Bartus, C.L.3    Sherman, T.G.4    Herman, M.M.5    Hyde, T.M.6    Kleinman, J.E.7    Akil, M.8
  • 127
    • 64649098447 scopus 로고    scopus 로고
    • Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia
    • Shibata, H.; Tani, A.; Chikuhara, T.; Kikuta, R.; Sakai, M.; Ninomiya, H.; Tashiro, N.; Iwata, N.; Ozaki, N.; Fukumaki, Y. Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia. Psychiatry Res., 2009, 167 (1-2), 88-96.
    • (2009) Psychiatry Res , vol.167 , Issue.1-2 , pp. 88-96
    • Shibata, H.1    Tani, A.2    Chikuhara, T.3    Kikuta, R.4    Sakai, M.5    Ninomiya, H.6    Tashiro, N.7    Iwata, N.8    Ozaki, N.9    Fukumaki, Y.10
  • 128
    • 33750215004 scopus 로고    scopus 로고
    • The schizophrenic faces of PICK1
    • Dev, K. K.; Henley, J. M. The schizophrenic faces of PICK1. Trends Pharmacol. Sci., 2006, 27 (11), 574-579.
    • (2006) Trends Pharmacol. Sci. , vol.27 , Issue.11 , pp. 574-579
    • Dev, K.K.1    Henley, J.M.2
  • 129
    • 45849134871 scopus 로고    scopus 로고
    • Presynaptic metabotropic glutamate receptors regulate glutamatergic input to dopamine neurons in the ventral tegmental area
    • de Rover, M.; Meye, F. J.; Ramakers, G. M. Presynaptic metabotropic glutamate receptors regulate glutamatergic input to dopamine neurons in the ventral tegmental area. Neuroscience, 2008, 154 (4), 1318-1323.
    • (2008) Neuroscience , vol.154 , Issue.4 , pp. 1318-1323
    • de Rover, M.1    Meye, F.J.2    Ramakers, G.M.3
  • 130
    • 38649091689 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats
    • Li, X.; Gardner, E. L.; Xi, Z. X. The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats. Neuropharmacology, 2008, 54 (3), 542-551.
    • (2008) Neuropharmacology , vol.54 , Issue.3 , pp. 542-551
    • Li, X.1    Gardner, E.L.2    Xi, Z.X.3
  • 131
    • 67349210998 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: Involvement of a ventral pallidal GABAergic mechanism
    • Li, X.; Li, J.; Peng, X. Q.; Spiller, K.; Gardner, E. L.; Xi, Z. X. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology, 2009, 34 (7), 1783-1796.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.7 , pp. 1783-1796
    • Li, X.1    Li, J.2    Peng, X.Q.3    Spiller, K.4    Gardner, E.L.5    Xi, Z.X.6
  • 132
    • 33745781189 scopus 로고    scopus 로고
    • Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7- deficient mice
    • Callaerts-Vegh, Z.; Beckers, T.; Ball, S. M.; Baeyens, F.; Callaerts, P. F.; Cryan, J. F.; Molnar, E.; D'Hooge, R. Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7- deficient mice. J. Neurosci., 2006, 26 (24), 6573-6582.
    • (2006) J. Neurosci. , vol.26 , Issue.24 , pp. 6573-6582
    • Callaerts-Vegh, Z.1    Beckers, T.2    Ball, S.M.3    Baeyens, F.4    Callaerts, P.F.5    Cryan, J.F.6    Molnar, E.7    D'Hooge, R.8
  • 133
    • 4143099070 scopus 로고    scopus 로고
    • Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory
    • Hölscher, C.; Schmid, S.; Pilz, P. K.; Sansig, G.; van der Putten, H.; Plappert, C. F. Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory. Behav. Brain Res., 2004, 154 (2), 473-481.
    • (2004) Behav. Brain Res. , vol.154 , Issue.2 , pp. 473-481
    • Hölscher, C.1    Schmid, S.2    Pilz, P.K.3    Sansig, G.4    van der Putten, H.5    Plappert, C.F.6
  • 134
    • 25844517542 scopus 로고    scopus 로고
    • Lack of the metabotropic glutamate receptor subtype 7 selectively modulates Theta rhythm and working memory
    • Hölscher, C.; Schmid, S.; Pilz, P. K.; Sansig, G.; van der Putten, H.; Plappert, C. F. Lack of the metabotropic glutamate receptor subtype 7 selectively modulates Theta rhythm and working memory. Learn. Mem., 2005, 12 (5), 450-455.
    • (2005) Learn. Mem. , vol.12 , Issue.5 , pp. 450-455
    • Hölscher, C.1    Schmid, S.2    Pilz, P.K.3    Sansig, G.4    van der Putten, H.5    Plappert, C.F.6
  • 135
    • 0038065932 scopus 로고    scopus 로고
    • Altered short-term synaptic plasticity in mice lacking the metabotropic glutamate receptor mGlu7
    • Bushell, T. J.; Sansig, G.; Collett, V. J.; van der, P. H.; Collingridge, G. L. Altered short-term synaptic plasticity in mice lacking the metabotropic glutamate receptor mGlu7. Sci. World J., 2002, 2, 730-737.
    • (2002) Sci. World J. , vol.2 , pp. 730-737
    • Bushell, T.J.1    Sansig, G.2    Collett, V.J.3    van der, P.H.4    Collingridge, G.L.5
  • 136
  • 138
    • 0036386828 scopus 로고    scopus 로고
    • Cystine/glutamate exchange serves as the source for extracellular glutamate: Modifications by repeated cocaine administration
    • Baker, D. A.; Shen, H.; Kalivas, P. W. Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino Acids, 2002, 23 (1-3), 161-162.
    • (2002) Amino Acids , vol.23 , Issue.1-3 , pp. 161-162
    • Baker, D.A.1    Shen, H.2    Kalivas, P.W.3
  • 139
    • 21844443565 scopus 로고    scopus 로고
    • Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking
    • Moran, M. M.; McFarland, K.; Melendez, R. I.; Kalivas, P. W.; Seamans, J. K. Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. J. Neurosci., 2005, 25 (27), 6389-6393.
    • (2005) J. Neurosci. , vol.25 , Issue.27 , pp. 6389-6393
    • Moran, M.M.1    McFarland, K.2    Melendez, R.I.3    Kalivas, P.W.4    Seamans, J.K.5
  • 140
    • 51149092387 scopus 로고    scopus 로고
    • Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors
    • Milton, A. L.; Lee, J. L.; Butler, V. J.; Gardner, R.; Everitt, B. J. Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors. J. Neurosci., 2008, 28 (33), 8230-8237.
    • (2008) J. Neurosci. , vol.28 , Issue.33 , pp. 8230-8237
    • Milton, A.L.1    Lee, J.L.2    Butler, V.J.3    Gardner, R.4    Everitt, B.J.5
  • 141
    • 48749127367 scopus 로고    scopus 로고
    • Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors
    • Zweifel, L. S.; Argilli, E.; Bonci, A.; Palmiter, R. D. Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron, 2008, 59 (3), 486-496.
    • (2008) Neuron , vol.59 , Issue.3 , pp. 486-496
    • Zweifel, L.S.1    Argilli, E.2    Bonci, A.3    Palmiter, R.D.4
  • 142
    • 33748968301 scopus 로고    scopus 로고
    • Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: Potential insight into their anti-addictive properties
    • Lominac, K. D.; Kapasova, Z.; Hannun, R. A.; Patterson, C.; Middaugh, L. D.; Szumlinski, K. K. Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties. Drug Alcohol Depend., 2006, 85 (2), 142-156.
    • (2006) Drug Alcohol Depend , vol.85 , Issue.2 , pp. 142-156
    • Lominac, K.D.1    Kapasova, Z.2    Hannun, R.A.3    Patterson, C.4    Middaugh, L.D.5    Szumlinski, K.K.6
  • 143
    • 33746867592 scopus 로고    scopus 로고
    • Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats
    • Dravolina, O. A.; Danysz, W.; Bespalov, A. Y. Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats. Psychopharmacology (Berl.,) 2006, 187 (4), 397-404.
    • (2006) Psychopharmacology (Berl.,) , vol.187 , Issue.4 , pp. 397-404
    • Dravolina, O.A.1    Danysz, W.2    Bespalov, A.Y.3
  • 144
    • 78650575007 scopus 로고    scopus 로고
    • Pretreatment with Group I metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice
    • Kotlinska, J.; Bochenski, M. Pretreatment with Group I metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice. Neurotox. Res., 2009, 19 (1), 23-30.
    • (2009) Neurotox. Res. , vol.19 , Issue.1 , pp. 23-30
    • Kotlinska, J.1    Bochenski, M.2
  • 145
    • 72649085319 scopus 로고    scopus 로고
    • Effects of mGluR1 antagonism in the dorsal hippocampus on drug contextinduced reinstatement of cocaine-seeking behavior in rats
    • Xie, X.; Ramirez, D. R.; Lasseter, H. C.; Fuchs, R. A. Effects of mGluR1 antagonism in the dorsal hippocampus on drug contextinduced reinstatement of cocaine-seeking behavior in rats. Psychopharmacology (Berl.,) 2010, 208 (1), 1-11.
    • (2010) Psychopharmacology (Berl.,) , vol.208 , Issue.1 , pp. 1-11
    • Xie, X.1    Ramirez, D.R.2    Lasseter, H.C.3    Fuchs, R.A.4
  • 146
    • 33846292496 scopus 로고    scopus 로고
    • Y. mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats
    • Dravolina, O. A.; Zakharova, E. S.; Shekunova, E. V.; Zvartau, E. E.; Danysz, W.; Bespalov, A. Y. mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats. Neuropharmacology, 2007, 52 (2), 263-269.
    • (2007) Neuropharmacology , vol.52 , Issue.2 , pp. 263-269
    • Dravolina, O.A.1    Zakharova, E.S.2    Shekunova, E.V.3    Zvartau, E.E.4    Danysz, W.5    Bespalov, A.6
  • 147
    • 33847331564 scopus 로고    scopus 로고
    • Comparison of the effects of mGluR1 and mGluR5 antagonists on the expression of behavioral sensitization to the locomotor effect of morphine and the morphine withdrawal jumping in mice
    • Kotlinska, J.; Bochenski, M. Comparison of the effects of mGluR1 and mGluR5 antagonists on the expression of behavioral sensitization to the locomotor effect of morphine and the morphine withdrawal jumping in mice. Eur. J. Pharmacol., 2007, 558 (1-3), 113-118.
    • (2007) Eur. J. Pharmacol. , vol.558 , Issue.1-3 , pp. 113-118
    • Kotlinska, J.1    Bochenski, M.2
  • 148
    • 50849129629 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: Relationship to acamprosate actions
    • Blednov, Y. A.; Adron, H. R. Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. Int. J. Neuropsychopharmacol., 2008, 11 (6), 775-793.
    • (2008) Int. J. Neuropsychopharmacol. , vol.11 , Issue.6 , pp. 775-793
    • Blednov, Y.A.1    Adron, H.R.2
  • 149
    • 49949092685 scopus 로고    scopus 로고
    • Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: Blockade by the mGluR5 antagonist MPEP
    • Schroeder, J. P.; Spanos, M.; Stevenson, J. R.; Besheer, J.; Salling, M.; Hodge, C. W. Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP. Neuropharmacology, 2008, 55 (4), 546-554.
    • (2008) Neuropharmacology , vol.55 , Issue.4 , pp. 546-554
    • Schroeder, J.P.1    Spanos, M.2    Stevenson, J.R.3    Besheer, J.4    Salling, M.5    Hodge, C.W.6
  • 150
    • 19244387486 scopus 로고    scopus 로고
    • Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotinetriggered relapse to nicotine-seeking
    • Tessari, M.; Pilla, M.; Andreoli, M.; Hutcheson, D. M.; Heidbreder, C. A. Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotinetriggered relapse to nicotine-seeking. Eur. J. Pharmacol., 2004, 499 (1-2), 121-133.
    • (2004) Eur. J. Pharmacol. , vol.499 , Issue.1-2 , pp. 121-133
    • Tessari, M.1    Pilla, M.2    Andreoli, M.3    Hutcheson, D.M.4    Heidbreder, C.A.5
  • 151
    • 14344261021 scopus 로고    scopus 로고
    • Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)- pyridine in squirrel monkeys: Comparison with dizocilpine
    • Lee, B.; Platt, D. M.; Rowlett, J. K.; Adewale, A. S.; Spealman, R. D. Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)- pyridine in squirrel monkeys: comparison with dizocilpine. J. Pharmacol. Exp. Ther., 2005, 312 (3), 1232-1240.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , Issue.3 , pp. 1232-1240
    • Lee, B.1    Platt, D.M.2    Rowlett, J.K.3    Adewale, A.S.4    Spealman, R.D.5
  • 152
    • 51249102144 scopus 로고    scopus 로고
    • Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: Comparison with dizocilpine
    • Platt, D. M.; Rowlett, J. K.; Spealman, R. D. Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: comparison with dizocilpine. Psychopharmacology (Berl), 2008, 200 (2), 167-176.
    • (2008) Psychopharmacology (Berl) , vol.200 , Issue.2 , pp. 167-176
    • Platt, D.M.1    Rowlett, J.K.2    Spealman, R.D.3
  • 153
    • 33748062344 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP
    • Lea, P. M.; Faden, A. I. Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. CNS Drug Rev., 2006, 12 (2), 149-166.
    • (2006) CNS Drug Rev , vol.12 , Issue.2 , pp. 149-166
    • Lea, P.M.1    Faden, A.I.2
  • 154
    • 0035137866 scopus 로고    scopus 로고
    • Functional coexpression of excitatory mGluR1 and mGluR5 on striatal cholinergic interneurons
    • Pisani, A.; Bonsi, P.; Centonze, D.; Bernardi, G.; Calabresi, P. Functional coexpression of excitatory mGluR1 and mGluR5 on striatal cholinergic interneurons. Neuropharmacology, 2001, 40 (3), 460-463.
    • (2001) Neuropharmacology , vol.40 , Issue.3 , pp. 460-463
    • Pisani, A.1    Bonsi, P.2    Centonze, D.3    Bernardi, G.4    Calabresi, P.5
  • 155
    • 59949088634 scopus 로고    scopus 로고
    • mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats
    • Gass, J. T.; Osborne, M. P.; Watson, N. L.; Brown, J. L.; Olive, M. F. mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats. Neuropsychopharmacology, 2009, 34 (4), 820-833.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.4 , pp. 820-833
    • Gass, J.T.1    Osborne, M.P.2    Watson, N.L.3    Brown, J.L.4    Olive, M.F.5
  • 157
    • 0344980107 scopus 로고    scopus 로고
    • Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models
    • Klodzinska, A.; Chojnacka-Wojcik, E.; Palucha, A.; Branski, P.; Popik, P.; Pilc, A. Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models. Neuropharmacology, 1999, 38 (12), 1831-1839.
    • (1999) Neuropharmacology , vol.38 , Issue.12 , pp. 1831-1839
    • Klodzinska, A.1    Chojnacka-Wojcik, E.2    Palucha, A.3    Branski, P.4    Popik, P.5    Pilc, A.6
  • 158
    • 28844433298 scopus 로고    scopus 로고
    • Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)- 3,4-DCPG
    • Bäckström, P.; Hyytiä, P. Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)- 3,4-DCPG. Eur. J. Pharmacol., 2005, 528 (1-3), 110-118.
    • (2005) Eur. J. Pharmacol. , vol.528 , Issue.1-3 , pp. 110-118
    • Bäckström, P.1    Hyytiä, P.2
  • 159
    • 33646565030 scopus 로고    scopus 로고
    • The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and foodseeking behavior in rats
    • Peters, J.; Kalivas, P. W. The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and foodseeking behavior in rats. Psychopharmacology (Berl), 2006, 186 (2), 143-149.
    • (2006) Psychopharmacology (Berl) , vol.186 , Issue.2 , pp. 143-149
    • Peters, J.1    Kalivas, P.W.2
  • 160
    • 2442672865 scopus 로고    scopus 로고
    • Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: Comparison between cocaine and a potent conventional reinforcer
    • Baptista, M. A.; Martin-Fardon, R.; Weiss, F. Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer. J. Neurosci., 2004, 24 (20), 4723-4727.
    • (2004) J. Neurosci. , vol.24 , Issue.20 , pp. 4723-4727
    • Baptista, M.A.1    Martin-Fardon, R.2    Weiss, F.3
  • 161
    • 33748760601 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking
    • Bossert, J. M.; Gray, S. M.; Lu, L.; Shaham, Y. Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking. Neuropsychopharmacology, 2006, 31 (10), 2197-2209.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2197-2209
    • Bossert, J.M.1    Gray, S.M.2    Lu, L.3    Shaham, Y.4
  • 162
    • 34548151226 scopus 로고    scopus 로고
    • Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence
    • Liechti, M. E.; Lhuillier, L.; Kaupmann, K.; Markou, A. Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence. J. Neurosci., 2007, 27 (34), 9077-9085.
    • (2007) J. Neurosci. , vol.27 , Issue.34 , pp. 9077-9085
    • Liechti, M.E.1    Lhuillier, L.2    Kaupmann, K.3    Markou, A.4
  • 163
    • 33749166779 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala
    • Zhao, Y.; Dayas, C. V.; Aujla, H.; Baptista, M. A.; Martin-Fardon, R.; Weiss, F. Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala. J. Neurosci., 2006, 26 (39), 9967-9974.
    • (2006) J. Neurosci. , vol.26 , Issue.39 , pp. 9967-9974
    • Zhao, Y.1    Dayas, C.V.2    Aujla, H.3    Baptista, M.A.4    Martin-Fardon, R.5    Weiss, F.6
  • 164
    • 9344230367 scopus 로고    scopus 로고
    • A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking
    • Bossert, J. M.; Liu, S. Y.; Lu, L.; Shaham, Y. A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking. J. Neurosci., 2004, 24 (47), 10726-10730.
    • (2004) J. Neurosci. , vol.24 , Issue.47 , pp. 10726-10730
    • Bossert, J.M.1    Liu, S.Y.2    Lu, L.3    Shaham, Y.4
  • 165
    • 36448952285 scopus 로고    scopus 로고
    • Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking
    • Vadasz, C.; Saito, M.; Gyetvai, B. M.; Oros, M.; Szakall, I.; Kovacs, K. M.; Prasad, V. V.; Toth, R. Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking. Genomics, 2007, 90 (6), 690-702.
    • (2007) Genomics , vol.90 , Issue.6 , pp. 690-702
    • Vadasz, C.1    Saito, M.2    Gyetvai, B.M.3    Oros, M.4    Szakall, I.5    Kovacs, K.M.6    Prasad, V.V.7    Toth, R.8
  • 166
    • 40849142336 scopus 로고    scopus 로고
    • Genotype patterns that contribute to increased risk for or protection from developing heroin addiction
    • Nielsen, D. A.; Ji, F.; Yuferov, V.; Ho, A.; Chen, A.; Levran, O.; Ott, J.; Kreek, M. J. Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. Mol. Psychiatry, 2008, 13 (4), 417-428.
    • (2008) Mol. Psychiatry. , vol.13 , Issue.4 , pp. 417-428
    • Nielsen, D.A.1    Ji, F.2    Yuferov, V.3    Ho, A.4    Chen, A.5    Levran, O.6    Ott, J.7    Kreek, M.J.8
  • 167
    • 33645107443 scopus 로고    scopus 로고
    • Tolerability and safety of fluvoxamine and other antidepressants
    • Westenberg, H. G.; Sandner, C. Tolerability and safety of fluvoxamine and other antidepressants. Int. J. Clin. Pract., 2006, 60 (4), 482-491.
    • (2006) Int. J. Clin. Pract. , vol.60 , Issue.4 , pp. 482-491
    • Westenberg, H.G.1    Sandner, C.2
  • 168
    • 3442891499 scopus 로고    scopus 로고
    • Tolerability issues during long-term treatment with antidepressants
    • Cassano, P.; Fava, M. Tolerability issues during long-term treatment with antidepressants. Ann. Clin. Psychiatry, 2004, 16 (1), 15-25.
    • (2004) Ann. Clin. Psychiatry. , vol.16 , Issue.1 , pp. 15-25
    • Cassano, P.1    Fava, M.2
  • 169
    • 33846493529 scopus 로고    scopus 로고
    • Medical disorders affect health outcome and general functioning depending on comorbid major depression in the general population
    • Baune, B. T.; Adrian, I.; Jacobi, F. Medical disorders affect health outcome and general functioning depending on comorbid major depression in the general population. J. Psychosom. Res., 2007, 62 (2), 109-118.
    • (2007) J. Psychosom. Res. , vol.62 , Issue.2 , pp. 109-118
    • Baune, B.T.1    Adrian, I.2    Jacobi, F.3
  • 171
    • 0028051806 scopus 로고
    • Drug-induced actions on brain neurotransmitter systems and changes in the behaviors and emotions of depressed patients
    • Katz, M. M.; Maas, J. W.; Frazer, A.; Koslow, S. H.; Bowden, C. L.; Berman, N.; Swann, A. C.; Stokes, P. E. Drug-induced actions on brain neurotransmitter systems and changes in the behaviors and emotions of depressed patients. Neuropsychopharmacology, 1994, 11 (2), 89-100.
    • (1994) Neuropsychopharmacology , vol.11 , Issue.2 , pp. 89-100
    • Katz, M.M.1    Maas, J.W.2    Frazer, A.3    Koslow, S.H.4    Bowden, C.L.5    Berman, N.6    Swann, A.C.7    Stokes, P.E.8
  • 172
    • 0021995125 scopus 로고
    • Effects of amitriptyline and imipramine on brain amine neurotransmitter metabolites in cerebrospinal fluid
    • Bowden, C. L.; Koslow, S. H.; Hanin, I.; Maas, J. W.; Davis, J. M.; Robins, E. Effects of amitriptyline and imipramine on brain amine neurotransmitter metabolites in cerebrospinal fluid. Clin. Pharmacol. Ther., 1985, 37 (3), 316-324.
    • (1985) Clin. Pharmacol. Ther. , vol.37 , Issue.3 , pp. 316-324
    • Bowden, C.L.1    Koslow, S.H.2    Hanin, I.3    Maas, J.W.4    Davis, J.M.5    Robins, E.6
  • 173
    • 69749103588 scopus 로고    scopus 로고
    • The serotonin-1A receptor in anxiety disorders
    • Akimova, E.; Lanzenberger, R.; Kasper, S. The serotonin-1A receptor in anxiety disorders. Biol. Psychiatry, 2009, 66 (7), 627-635.
    • (2009) Biol. Psychiatry. , vol.66 , Issue.7 , pp. 627-635
    • Akimova, E.1    Lanzenberger, R.2    Kasper, S.3
  • 174
    • 46749121905 scopus 로고    scopus 로고
    • Rapid onset of antidepressant action: A new paradigm in the research and treatment of major depressive disorder
    • Machado-Vieira, R.; Salvadore, G.; Luckenbaugh, D. A.; Manji, H. K.; Zarate, C. A., Jr. Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder. J. Clin. Psychiatry, 2008, 69 (6), 946-958.
    • (2008) J. Clin. Psychiatry. , vol.69 , Issue.6 , pp. 946-958
    • Machado-Vieira, R.1    Salvadore, G.2    Luckenbaugh, D.A.3    Manji, H.K.4    Zarate Jr., C.A.5
  • 176
    • 57749090403 scopus 로고    scopus 로고
    • Dual- and Triple-Acting agents for treating core and Co-morbid symptoms of major depression: Novel concepts, new drugs
    • Millan, M. J. Dual- and Triple-Acting agents for treating core and Co-morbid symptoms of major depression: novel concepts, new drugs. Neurotherapeutics, 2009, 6 (1), 53-77.
    • (2009) Neurotherapeutics , vol.6 , Issue.1 , pp. 53-77
    • Millan, M.J.1
  • 178
    • 0032524219 scopus 로고    scopus 로고
    • Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region
    • Pilc, A.; Branski, P.; Palucha, A.; Tokarski, K.; Bijak, M. Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region. Eur. J. Pharmacol., 1998, 349 (1), 83-87.
    • (1998) Eur. J. Pharmacol. , vol.349 , Issue.1 , pp. 83-87
    • Pilc, A.1    Branski, P.2    Palucha, A.3    Tokarski, K.4    Bijak, M.5
  • 179
    • 0343851555 scopus 로고    scopus 로고
    • Effect of chronic antidepressant or electroconvulsive shock treatment on mGLuR1a immunoreactivity expression in the rat hippocampus
    • Bajkowska, M.; Branski, P.; Smialowska, M.; Pilc, A. Effect of chronic antidepressant or electroconvulsive shock treatment on mGLuR1a immunoreactivity expression in the rat hippocampus. Pol. J. Pharmacol., 1999, 51 (6), 539-541.
    • (1999) Pol. J. Pharmacol. , vol.51 , Issue.6 , pp. 539-541
    • Bajkowska, M.1    Branski, P.2    Smialowska, M.3    Pilc, A.4
  • 180
    • 0036063314 scopus 로고    scopus 로고
    • Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus
    • Smialowska, M.; Szewczyk, B.; Branski, P.; Wieronska, J. M.; Palucha, A.; Bajkowska, M.; Pilc, A. Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus. Neuropharmacology, 2002, 42 (8), 1016-1023.
    • (2002) Neuropharmacology , vol.42 , Issue.8 , pp. 1016-1023
    • Smialowska, M.1    Szewczyk, B.2    Branski, P.3    Wieronska, J.M.4    Palucha, A.5    Bajkowska, M.6    Pilc, A.7
  • 182
    • 67849094100 scopus 로고    scopus 로고
    • Effects of mGluR5 and mGluR1 antagonists on anxiety-like behavior and learning in developing rats
    • Mikulecka, A.; Mares, P. Effects of mGluR5 and mGluR1 antagonists on anxiety-like behavior and learning in developing rats. Behav. Brain Res., 2009, 204 (1), 133-139.
    • (2009) Behav. Brain Res. , vol.204 , Issue.1 , pp. 133-139
    • Mikulecka, A.1    Mares, P.2
  • 183
    • 17744373871 scopus 로고    scopus 로고
    • The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: A comparison
    • Ballard, T. M.; Woolley, M. L.; Prinssen, E.; Huwyler, J.; Porter, R.; Spooren, W. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison. Psychopharmacology (Berl), 2005, 179 (1), 218-229.
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 218-229
    • Ballard, T.M.1    Woolley, M.L.2    Prinssen, E.3    Huwyler, J.4    Porter, R.5    Spooren, W.6
  • 184
    • 0033680311 scopus 로고    scopus 로고
    • Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2- methyl-6-(phenylethynyl)pyridine in rodents
    • Spooren, W. P.; Vassout, A.; Neijt, H. C.; Kuhn, R.; Gasparini, F.; Roux, S.; Porsolt, R. D.; Gentsch, C. Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2- methyl-6-(phenylethynyl)pyridine in rodents. J. Pharmacol. Exp. Ther., 2000, 295 (3), 1267-1275.
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , Issue.3 , pp. 1267-1275
    • Spooren, W.P.1    Vassout, A.2    Neijt, H.C.3    Kuhn, R.4    Gasparini, F.5    Roux, S.6    Porsolt, R.D.7    Gentsch, C.8
  • 185
    • 3342946097 scopus 로고    scopus 로고
    • mGlu5 receptor antagonists: A novel class of anxiolytics?
    • Spooren, W.; Gasparini, F. mGlu5 receptor antagonists: a novel class of anxiolytics? Drug News Perspect., 2004, 17 (4), 251-257.
    • (2004) Drug News Perspect , vol.17 , Issue.4 , pp. 251-257
    • Spooren, W.1    Gasparini, F.2
  • 186
    • 0035069188 scopus 로고    scopus 로고
    • Potential anxiolytic- and antidepressant- like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist
    • Tatarczynska, E.; Klodzinska, A.; Chojnacka-Wojcik, E.; Palucha, A.; Gasparini, F.; Kuhn, R.; Pilc, A. Potential anxiolytic- and antidepressant- like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. Br. J. Pharmacol., 2001, 132 (7), 1423-1430.
    • (2001) Br. J. Pharmacol. , vol.132 , Issue.7 , pp. 1423-1430
    • Tatarczynska, E.1    Klodzinska, A.2    Chojnacka-Wojcik, E.3    Palucha, A.4    Gasparini, F.5    Kuhn, R.6    Pilc, A.7
  • 187
    • 72149100751 scopus 로고    scopus 로고
    • Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity
    • Spanka, C.; Glatthar, R.; Desrayaud, S.; Fendt, M.; Orain, D.; Troxler, T.; Vranesic, I. Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity. Bioorg. Med. Chem. Lett., 2010, 20 (1), 184-188.
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , Issue.1 , pp. 184-188
    • Spanka, C.1    Glatthar, R.2    Desrayaud, S.3    Fendt, M.4    Orain, D.5    Troxler, T.6    Vranesic, I.7
  • 188
    • 57049084065 scopus 로고    scopus 로고
    • Investigation on tolerance development to subchronic blockade of mGluR5 in models of learning, anxiety, and levodopainduced dyskinesia in rats
    • Gravius, A.; Dekundy, A.; Nagel, J.; More, L.; Pietraszek, M.; Danysz, W. Investigation on tolerance development to subchronic blockade of mGluR5 in models of learning, anxiety, and levodopainduced dyskinesia in rats. J. Neural. Transm., 2008, 115 (12), 1609-1619.
    • (2008) J. Neural. Transm. , vol.115 , Issue.12 , pp. 1609-1619
    • Gravius, A.1    Dekundy, A.2    Nagel, J.3    More, L.4    Pietraszek, M.5    Danysz, W.6
  • 189
    • 67349111311 scopus 로고    scopus 로고
    • Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanisms
    • George, S. A.; Hutson, P. H.; Stephens, D. N. Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanisms. Psychopharmacology (Berl.,) 2009, 204 (3), 499-509.
    • (2009) Psychopharmacology (Berl.,) , vol.204 , Issue.3 , pp. 499-509
    • George, S.A.1    Hutson, P.H.2    Stephens, D.N.3
  • 190
    • 0035695488 scopus 로고    scopus 로고
    • Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression
    • Wieronska, J. M.; Branski, P.; Szewczyk, B.; Palucha, A.; Papp, M.; Gruca, P.; Moryl, E.; Pilc, A. Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression. Pol. J. Pharmacol., 2001, 53 (6), 659-662.
    • (2001) Pol. J. Pharmacol. , vol.53 , Issue.6 , pp. 659-662
    • Wieronska, J.M.1    Branski, P.2    Szewczyk, B.3    Palucha, A.4    Papp, M.5    Gruca, P.6    Moryl, E.7    Pilc, A.8
  • 191
    • 23944453080 scopus 로고    scopus 로고
    • Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist
    • Palucha, A.; Branski, P.; Szewczyk, B.; Wieronska, J. M.; Klak, K.; Pilc, A. Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Pharmacol. Biochem. Behav., 2005, 81 (4), 901-906.
    • (2005) Pharmacol. Biochem. Behav. , vol.81 , Issue.4 , pp. 901-906
    • Palucha, A.1    Branski, P.2    Szewczyk, B.3    Wieronska, J.M.4    Klak, K.5    Pilc, A.6
  • 192
    • 33751190762 scopus 로고    scopus 로고
    • Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests
    • Belozertseva, I. V.; Kos, T.; Popik, P.; Danysz, W.; Bespalov, A. Y. Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests. Eur. Neuropsychopharmacol., 2007, 17 (3), 172-179.
    • (2007) Eur. Neuropsychopharmacol. , vol.17 , Issue.3 , pp. 172-179
    • Belozertseva, I.V.1    Kos, T.2    Popik, P.3    Danysz, W.4    Bespalov, A.Y.5
  • 193
    • 33748999574 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice
    • Li, X.; Need, A. B.; Baez, M.; Witkin, J. M. Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice. J. Pharmacol. Exp. Ther., 2006, 319 (1), 254-259.
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , Issue.1 , pp. 254-259
    • Li, X.1    Need, A.B.2    Baez, M.3    Witkin, J.M.4
  • 198
    • 65249100748 scopus 로고    scopus 로고
    • Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus
    • Wieronska, J. M.; Legutko, B.; Dudys, D.; Pilc, A. Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus. Pharmacol. Rep., 2008, 60 (6), 844-855.
    • (2008) Pharmacol. Rep. , vol.60 , Issue.6 , pp. 844-855
    • Wieronska, J.M.1    Legutko, B.2    Dudys, D.3    Pilc, A.4
  • 202
    • 17044396861 scopus 로고    scopus 로고
    • AMPA receptor stimulation mediates the antidepressant-like effect of a group II metabotropic glutamate receptor antagonist
    • Karasawa, J.; Shimazaki, T.; Kawashima, N.; Chaki, S. AMPA receptor stimulation mediates the antidepressant-like effect of a group II metabotropic glutamate receptor antagonist. Brain Res., 2005, 1042 (1), 92-98.
    • (2005) Brain Res , vol.1042 , Issue.1 , pp. 92-98
    • Karasawa, J.1    Shimazaki, T.2    Kawashima, N.3    Chaki, S.4
  • 203
    • 0842288995 scopus 로고    scopus 로고
    • Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039
    • Yoshimizu, T.; Chaki, S. Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039. Biochem Biophys. Res. Commun., 2004, 315 (2), 493-496.
    • (2004) Biochem Biophys. Res. Commun. , vol.315 , Issue.2 , pp. 493-496
    • Yoshimizu, T.1    Chaki, S.2
  • 204
    • 77949387830 scopus 로고    scopus 로고
    • Open questions in current models of antidepressant action
    • Tanti, A.; Belzung, C. Open questions in current models of antidepressant action. Br. J. Pharmacol., 2010, 159 (6), 1187-1200.
    • (2010) Br. J. Pharmacol. , vol.159 , Issue.6 , pp. 1187-1200
    • Tanti, A.1    Belzung, C.2
  • 207
    • 19944418868 scopus 로고    scopus 로고
    • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test
    • Cryan, J. F.; Valentino, R. J.; Lucki, I. Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci. Biobehav. Rev., 2005, 29 (4-5), 547-569.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , Issue.4-5 , pp. 547-569
    • Cryan, J.F.1    Valentino, R.J.2    Lucki, I.3
  • 208
    • 15244356054 scopus 로고    scopus 로고
    • Enhanced cocaine responsiveness and im paired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice
    • Morishima, Y.; Miyakawa, T.; Furuyashiki, T.; Tanaka, Y.; Mizuma, H.; Nakanishi, S. Enhanced cocaine responsiveness and im paired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice. Proc. Natl. Acad Sci. USA, 2005, 102 (11), 4170-4175.
    • (2005) Proc. Natl. Acad Sci. USA , vol.102 , Issue.11 , pp. 4170-4175
    • Morishima, Y.1    Miyakawa, T.2    Furuyashiki, T.3    Tanaka, Y.4    Mizuma, H.5    Nakanishi, S.6
  • 209
    • 20144385463 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors and neuroadaptation to antidepressants: Imipramineinduced down-regulation of beta-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands
    • Matrisciano, F.; Scaccianoce, S.; Del, B. P.; Panaccione, I.; Canudas, A. M.; Battaglia, G.; Riozzi, B.; Ngomba, R. T.; Molinaro, G.; Tatarelli, R.; Melchiorri, D.; Nicoletti, F. Metabotropic glutamate receptors and neuroadaptation to antidepressants: imipramineinduced down-regulation of beta-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands. J. Neurochem., 2005, 93 (5), 1345-1352.
    • (2005) J. Neurochem. , vol.93 , Issue.5 , pp. 1345-1352
    • Matrisciano, F.1    Scaccianoce, S.2    Del, B.P.3    Panaccione, I.4    Canudas, A.M.5    Battaglia, G.6    Riozzi, B.7    Ngomba, R.T.8    Molinaro, G.9    Tatarelli, R.10    Melchiorri, D.11    Nicoletti, F.12
  • 210
    • 49949084013 scopus 로고    scopus 로고
    • Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression
    • Bespalov, A. Y.; van Gaalen, M. M.; Sukhotina, I. A.; Wicke, K.; Mezler, M.; Schoemaker, H.; Gross, G. Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression. Eur. J. Pharmacol., 2008, 592 (1-3), 96-102.
    • (2008) Eur. J. Pharmacol. , vol.592 , Issue.1-3 , pp. 96-102
    • Bespalov, A.Y.1    van Gaalen, M.M.2    Sukhotina, I.A.3    Wicke, K.4    Mezler, M.5    Schoemaker, H.6    Gross, G.7
  • 211
    • 33744957683 scopus 로고    scopus 로고
    • An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats
    • Yoshimizu, T.; Shimazaki, T.; Ito, A.; Chaki, S. An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats. Psychopharmacology (Berl.,) 2006, 186 (4), 587-593.
    • (2006) Psychopharmacology (Berl.,) , vol.186 , Issue.4 , pp. 587-593
    • Yoshimizu, T.1    Shimazaki, T.2    Ito, A.3    Chaki, S.4
  • 212
    • 36348939957 scopus 로고    scopus 로고
    • Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex
    • Wieronska, J. M.; Klak, K.; Palucha, A.; Branski, P.; Pilc, A. Citalopram influences mGlu7, but not mGlu4 receptors' expression in the rat brain hippocampus and cortex. Brain Res., 2007, 1184, 88-95.
    • (2007) Brain Res , vol.1184 , pp. 88-95
    • Wieronska, J.M.1    Klak, K.2    Palucha, A.3    Branski, P.4    Pilc, A.5
  • 213
    • 0036971043 scopus 로고    scopus 로고
    • Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1- aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats
    • Tatarczynska, E.; Palucha, A.; Szewczyk, B.; Chojnacka-Wojcik, E.; Wieronska, J.; Pilc, A. Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1- aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats. Pol. J. Pharmacol., 2002, 54 (6), 707-710.
    • (2002) Pol. J. Pharmacol. , vol.54 , Issue.6 , pp. 707-710
    • Tatarczynska, E.1    Palucha, A.2    Szewczyk, B.3    Chojnacka-Wojcik, E.4    Wieronska, J.5    Pilc, A.6
  • 214
    • 33846666910 scopus 로고    scopus 로고
    • Combined administration of PHCCC, a positive allosteric modulator of mGlu4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant- like effects in rats
    • Klak, K.; Palucha, A.; Branski, P.; Sowa, M.; Pilc, A. Combined administration of PHCCC, a positive allosteric modulator of mGlu4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant- like effects in rats. Amino Acids, 2007, 32 (2), 169-172.
    • (2007) Amino Acids , vol.32 , Issue.2 , pp. 169-172
    • Klak, K.1    Palucha, A.2    Branski, P.3    Sowa, M.4    Pilc, A.5
  • 215
    • 0038391169 scopus 로고    scopus 로고
    • Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7
    • Cryan, J. F.; Kelly, P. H.; Neijt, H. C.; Sansig, G.; Flor, P. J.; van der, P. H. Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. Eur. J. Neurosci., 2003, 17 (11), 2409-2417.
    • (2003) Eur. J. Neurosci. , vol.17 , Issue.11 , pp. 2409-2417
    • Cryan, J.F.1    Kelly, P.H.2    Neijt, H.C.3    Sansig, G.4    Flor, P.J.5    van der, P.H.6
  • 217
    • 67650656649 scopus 로고    scopus 로고
    • The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems
    • Stachowicz, K.; Klodzinska, A.; Palucha-Poniewiera, A.; Schann, S.; Neuville, P.; Pilc, A. The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems. Neuropharmacology, 2009, 57 (3), 227-234.
    • (2009) Neuropharmacology , vol.57 , Issue.3 , pp. 227-234
    • Stachowicz, K.1    Klodzinska, A.2    Palucha-Poniewiera, A.3    Schann, S.4    Neuville, P.5    Pilc, A.6
  • 219
    • 0037112013 scopus 로고    scopus 로고
    • Startle reactivity and anxiety disorders: Aversive conditioning, context, and neurobiology
    • Grillon, C. Startle reactivity and anxiety disorders: aversive conditioning, context, and neurobiology. Biol. Psychiatry, 2002, 52 (10), 958-975.
    • (2002) Biol. Psychiatry. , vol.52 , Issue.10 , pp. 958-975
    • Grillon, C.1
  • 220
    • 33745919520 scopus 로고    scopus 로고
    • Epidemiology of Parkinson's disease
    • de Lau, L. M.; Breteler, M. M. Epidemiology of Parkinson's disease. Lancet Neurol., 2006, 5 (6), 525-535.
    • (2006) Lancet Neurol , vol.5 , Issue.6 , pp. 525-535
    • de Lau, L.M.1    Breteler, M.M.2
  • 221
    • 74249084768 scopus 로고    scopus 로고
    • Systematic review of the prevalence and incidence of parkinson&rsquos disease in asia
    • Muangpaisan, W.; Hori, H.; Brayne, C. Systematic review of the prevalence and incidence of parkinson&rsquos disease in asia. J. Epidemiol., 2009, 19 (6), 281-293.
    • (2009) J. Epidemiol. , vol.19 , Issue.6 , pp. 281-293
    • Muangpaisan, W.1    Hori, H.2    Brayne, C.3
  • 222
    • 0028839005 scopus 로고
    • The functional anatomy of disorders of the basal ganglia
    • Albin, R. L.; Young, A. B.; Penney, J. B. The functional anatomy of disorders of the basal ganglia. Trends Neurosci., 1995, 18 (2), 63-64.
    • (1995) Trends Neurosci , vol.18 , Issue.2 , pp. 63-64
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 223
    • 67649538495 scopus 로고    scopus 로고
    • Anatomy and physiology of the basal ganglia: Relevance to Parkinson's disease and related disorders
    • Wichmann, T.; Delong, M. R. Anatomy and physiology of the basal ganglia: relevance to Parkinson's disease and related disorders. Handb. Clin. Neurol., 2007, 83, 1-18.
    • (2007) Handb. Clin. Neurol. , vol.83 , pp. 1-18
    • Wichmann, T.1    Delong, M.R.2
  • 224
    • 0028021805 scopus 로고
    • The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
    • Bergman, H.; Wichmann, T.; Karmon, B.; Delong, M. R. The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism. J. Neurophysiol., 1994, 72 (2), 507-520.
    • (1994) J. Neurophysiol. , vol.72 , Issue.2 , pp. 507-520
    • Bergman, H.1    Wichmann, T.2    Karmon, B.3    Delong, M.R.4
  • 226
    • 34247232731 scopus 로고    scopus 로고
    • Effects of 6-hydroxydopamine-induced severe or partial lesion of the nigrostriatal pathway on the neuronal activity of pallido-subthalamic network in the rat
    • Breit, S.; Bouali-Benazzouz, R.; Popa, R. C.; Gasser, T.; Benabid, A. L.; Benazzouz, A. Effects of 6-hydroxydopamine-induced severe or partial lesion of the nigrostriatal pathway on the neuronal activity of pallido-subthalamic network in the rat. Exp. Neurol., 2007, 205 (1), 36-47.
    • (2007) Exp. Neurol. , vol.205 , Issue.1 , pp. 36-47
    • Breit, S.1    Bouali-Benazzouz, R.2    Popa, R.C.3    Gasser, T.4    Benabid, A.L.5    Benazzouz, A.6
  • 227
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer, W.; Przedborski, S. Parkinson's disease: mechanisms and models. Neuron, 2003, 39 (6), 889-909.
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 228
    • 0034451725 scopus 로고    scopus 로고
    • Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: Implications for treatment of Parkinson's disease and related disorders
    • Rouse, S. T.; Marino, M. J.; Bradley, S. R.; Awad, H.; Wittmann, M.; Conn, P. J. Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: implications for treatment of Parkinson's disease and related disorders. Pharmacol. Ther., 2000, 88 (3), 427-435.
    • (2000) Pharmacol. Ther. , vol.88 , Issue.3 , pp. 427-435
    • Rouse, S.T.1    Marino, M.J.2    Bradley, S.R.3    Awad, H.4    Wittmann, M.5    Conn, P.J.6
  • 229
    • 0030898586 scopus 로고    scopus 로고
    • Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones
    • Pisani, A.; Calabresi, P.; Centonze, D.; Bernardi, G. Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones. Br. J. Pharmacol., 1997, 120 (6), 1007-1014.
    • (1997) Br. J. Pharmacol. , vol.120 , Issue.6 , pp. 1007-1014
    • Pisani, A.1    Calabresi, P.2    Centonze, D.3    Bernardi, G.4
  • 230
    • 0035216305 scopus 로고    scopus 로고
    • Selective activation of group I metabotropic glutamate receptors upregulates preprodynorphin, substance P, and preproenkephalin mRNA expression in rat dorsal striatum
    • Mao, L.; Wang, J. Q. Selective activation of group I metabotropic glutamate receptors upregulates preprodynorphin, substance P, and preproenkephalin mRNA expression in rat dorsal striatum. Synapse, 2001, 39 (1), 82-94.
    • (2001) Synapse , vol.39 , Issue.1 , pp. 82-94
    • Mao, L.1    Wang, J.Q.2
  • 231
    • 0037448018 scopus 로고    scopus 로고
    • The striopallidal pathway is involved in antiparkinsonian-like effects of the blockade of group I metabotropic glutamate receptors in rats
    • Ossowska, K.; Wardas, J.; Pietraszek, M.; Konieczny, J.; Wolfarth, S. The striopallidal pathway is involved in antiparkinsonian-like effects of the blockade of group I metabotropic glutamate receptors in rats. Neurosci. Lett., 2003, 342 (1-2), 21-24.
    • (2003) Neurosci. Lett. , vol.342 , Issue.1-2 , pp. 21-24
    • Ossowska, K.1    Wardas, J.2    Pietraszek, M.3    Konieczny, J.4    Wolfarth, S.5
  • 232
    • 40949141823 scopus 로고    scopus 로고
    • Intrapallidal metabotropic glutamate receptor activation in a rat model of Parkinson's disease: Behavioral and histological analyses
    • Agari, T.; Yasuhara, T.; Matsui, T.; Kuramoto, S.; Kondo, A.; Miyoshi, Y.; Shingo, T.; Borlongan, C. V.; Date, I. Intrapallidal metabotropic glutamate receptor activation in a rat model of Parkinson's disease: Behavioral and histological analyses. Brain Research, 2008, 1203, 189-196.
    • (2008) Brain Research , vol.1203 , pp. 189-196
    • Agari, T.1    Yasuhara, T.2    Matsui, T.3    Kuramoto, S.4    Kondo, A.5    Miyoshi, Y.6    Shingo, T.7    Borlongan, C.V.8    Date, I.9
  • 233
    • 33645050113 scopus 로고    scopus 로고
    • Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease
    • Dekundy, A.; Pietraszek, M.; Schaefer, D.; Cenci, M. A.; Danysz, W. Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease. Brain Res. Bull., 2006, 69 (3), 318-326.
    • (2006) Brain Res. Bull. , vol.69 , Issue.3 , pp. 318-326
    • Dekundy, A.1    Pietraszek, M.2    Schaefer, D.3    Cenci, M.A.4    Danysz, W.5
  • 234
    • 0036662945 scopus 로고    scopus 로고
    • Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism
    • Breysse, N.; Baunez, C.; Spooren, W.; Gasparini, F.; Amalric, M. Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism. J. Neurosci., 2002, 22 (13), 5669-5678.
    • (2002) J. Neurosci. , vol.22 , Issue.13 , pp. 5669-5678
    • Breysse, N.1    Baunez, C.2    Spooren, W.3    Gasparini, F.4    Amalric, M.5
  • 235
    • 0141856474 scopus 로고    scopus 로고
    • Metabotropic Glutamate 5 Receptor Blockade Alleviates Akinesia by Normalizing Activity of Selective Basal-Ganglia Structures in Parkinsonian Rats
    • Breysse, N.; Amalric, M.; Salin, P. Metabotropic Glutamate 5 Receptor Blockade Alleviates Akinesia by Normalizing Activity of Selective Basal-Ganglia Structures in Parkinsonian Rats. J. Neurosci., 2003, 23 (23), 8302-8309.
    • (2003) J. Neurosci. , vol.23 , Issue.23 , pp. 8302-8309
    • Breysse, N.1    Amalric, M.2    Salin, P.3
  • 236
    • 0035959976 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl--aspartate responses in medium spiny striatal neurons
    • Pisani, A.; Gubellini, P.; Bonsi, P.; Conquet, F.; Picconi, B.; Centonze, D.; Bernardi, G.; Calabresi, P. Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl--aspartate responses in medium spiny striatal neurons. Neuroscience, 2001, 106 (3), 579-587.
    • (2001) Neuroscience , vol.106 , Issue.3 , pp. 579-587
    • Pisani, A.1    Gubellini, P.2    Bonsi, P.3    Conquet, F.4    Picconi, B.5    Centonze, D.6    Bernardi, G.7    Calabresi, P.8
  • 237
    • 33644955961 scopus 로고    scopus 로고
    • Blockade of mGluR glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease
    • Phillips, J. M.; Lam, H. A.; Ackerson, L. C.; Maidment, N. T. Blockade of mGluR glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease. Eur. J. Neurosci., 2006, 23 (1), 151-160.
    • (2006) Eur. J. Neurosci. , vol.23 , Issue.1 , pp. 151-160
    • Phillips, J.M.1    Lam, H.A.2    Ackerson, L.C.3    Maidment, N.T.4
  • 238
    • 67649847847 scopus 로고    scopus 로고
    • Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: Effects on motor behavior and striatal nuclear signaling
    • Rylander, D.; Recchia, A.; Mela, F.; Dekundy, A.; Danysz, W.; Cenci, M. A. Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling. J. Pharmacol. Exp. Ther., 2009, 330 (1), 227-235.
    • (2009) J. Pharmacol. Exp. Ther. , vol.330 , Issue.1 , pp. 227-235
    • Rylander, D.1    Recchia, A.2    Mela, F.3    Dekundy, A.4    Danysz, W.5    Cenci, M.A.6
  • 239
    • 34047186385 scopus 로고    scopus 로고
    • Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease
    • Mela, F.; Marti, M.; Dekundy, A.; Danysz, W.; Morari, M.; Cenci, M. A. Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease. J. Neurochem., 2007, 101 (2), 483-497.
    • (2007) J. Neurochem. , vol.101 , Issue.2 , pp. 483-497
    • Mela, F.1    Marti, M.2    Dekundy, A.3    Danysz, W.4    Morari, M.5    Cenci, M.A.6
  • 240
    • 0012357275 scopus 로고    scopus 로고
    • The mGlu5 receptor antagonist SIB-1830 reduces l-DOPA-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease
    • 17
    • Hill, M. P.; McGuire, S. G.; Crossman, A. R.; Brotchie, J. M. The mGlu5 receptor antagonist SIB-1830 reduces l-DOPA-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. Abstr. Soc. Neurosci., 2001, 27, p.200.17.
    • (2001) Abstr. Soc. Neurosci. , vol.27 , pp. 200
    • Hill, M.P.1    McGuire, S.G.2    Crossman, A.R.3    Brotchie, J.M.4
  • 242
    • 26944465351 scopus 로고    scopus 로고
    • Neuroprotective effects of metabotropic glutamate receptor ligands in a 6-hydroxydopamine rodent model of Parkinson's disease
    • Vernon, A. C.; Palmer, S.; Datla, K. P.; Zbarsky, V.; Croucher, M. J.; Dexter, D. T. Neuroprotective effects of metabotropic glutamate receptor ligands in a 6-hydroxydopamine rodent model of Parkinson's disease. Eur. J. Neurosci., 2005, 22 (7), 1799-1806.
    • (2005) Eur. J. Neurosci. , vol.22 , Issue.7 , pp. 1799-1806
    • Vernon, A.C.1    Palmer, S.2    Datla, K.P.3    Zbarsky, V.4    Croucher, M.J.5    Dexter, D.T.6
  • 243
    • 35248859709 scopus 로고    scopus 로고
    • Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo
    • Vernon, A. C.; Zbarsky, V.; Datla, K. P.; Croucher, M. J.; Dexter, D. T. Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo. J. Neurochem., 2007, 103 (3), 1075-1091.
    • (2007) J. Neurochem. , vol.103 , Issue.3 , pp. 1075-1091
    • Vernon, A.C.1    Zbarsky, V.2    Datla, K.P.3    Croucher, M.J.4    Dexter, D.T.5
  • 244
    • 0035074475 scopus 로고    scopus 로고
    • Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease
    • Blandini, F.; Nappi, G.; Greenamyre, J. T. Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease. Ann. Neurol., 2001, 49 (4), 525-529.
    • (2001) Ann. Neurol. , vol.49 , Issue.4 , pp. 525-529
    • Blandini, F.1    Nappi, G.2    Greenamyre, J.T.3
  • 245
    • 0029897501 scopus 로고    scopus 로고
    • Subthalamic nucleus lesion in rats prevents dopaminergic nigral neuron degeneration after striatal 6-OHDA injection: Behavioural and immunohistochemical studies
    • Piallat, B.; Benazzouz, A.; Benabid, A. L. Subthalamic nucleus lesion in rats prevents dopaminergic nigral neuron degeneration after striatal 6-OHDA injection: behavioural and immunohistochemical studies. Eur. J. Neurosci., 1996, 8 (7), 1408-1414.
    • (1996) Eur. J. Neurosci. , vol.8 , Issue.7 , pp. 1408-1414
    • Piallat, B.1    Benazzouz, A.2    Benabid, A.L.3
  • 246
    • 0742322858 scopus 로고    scopus 로고
    • Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine in mice
    • Battaglia, G.; Busceti, C. L.; Molinaro, G.; Biagioni, F.; Storto, M.; Fornai, F.; Nicoletti, F.; Bruno, V. Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine in mice. J. Neurosci., 2004, 24 (4), 828-835.
    • (2004) J. Neurosci. , vol.24 , Issue.4 , pp. 828-835
    • Battaglia, G.1    Busceti, C.L.2    Molinaro, G.3    Biagioni, F.4    Storto, M.5    Fornai, F.6    Nicoletti, F.7    Bruno, V.8
  • 248
    • 0033967160 scopus 로고    scopus 로고
    • The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine- treated rat
    • Dawson, L.; Chadha, A.; Megalou, M.; Duty, S. The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine- treated rat. Br. J. Pharmacol., 2000, 129 (3), 541-546.
    • (2000) Br. J. Pharmacol. , vol.129 , Issue.3 , pp. 541-546
    • Dawson, L.1    Chadha, A.2    Megalou, M.3    Duty, S.4
  • 249
    • 0034193374 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors inhibits synaptic excitation of the substantia Nigra pars reticulata
    • Bradley, S. R.; Marino, M. J.; Wittmann, M.; Rouse, S. T.; Awad, H.; Levey, A. I.; Conn, P. J. Activation of group II metabotropic glutamate receptors inhibits synaptic excitation of the substantia Nigra pars reticulata. J. Neurosci., 2000, 20 (9), 3085-3094.
    • (2000) J. Neurosci. , vol.20 , Issue.9 , pp. 3085-3094
    • Bradley, S.R.1    Marino, M.J.2    Wittmann, M.3    Rouse, S.T.4    Awad, H.5    Levey, A.I.6    Conn, P.J.7
  • 251
    • 0037493477 scopus 로고    scopus 로고
    • Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
    • Battaglia, G.; Busceti, C. L.; Pontarelli, F.; Biagioni, F.; Fornai, F.; Paparelli, A.; Bruno, V.; Ruggieri, S.; Nicoletti, F. Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuropharmacology, 2003, 45 (2), 155-166.
    • (2003) Neuropharmacology , vol.45 , Issue.2 , pp. 155-166
    • Battaglia, G.1    Busceti, C.L.2    Pontarelli, F.3    Biagioni, F.4    Fornai, F.5    Paparelli, A.6    Bruno, V.7    Ruggieri, S.8    Nicoletti, F.9
  • 252
    • 28544440545 scopus 로고    scopus 로고
    • Modulation of excitatory synaptic transmission by endogenous glutamate acting on presynaptic group II mGluRs in rat substantia nigra compacta
    • Wang, L.; Kitai, S. T.; Xiang, Z. Modulation of excitatory synaptic transmission by endogenous glutamate acting on presynaptic group II mGluRs in rat substantia nigra compacta. J. Neurosci. Res., 2005, 82 (6), 778-787.
    • (2005) J. Neurosci. Res. , vol.82 , Issue.6 , pp. 778-787
    • Wang, L.1    Kitai, S.T.2    Xiang, Z.3
  • 253
    • 0033611972 scopus 로고    scopus 로고
    • Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia
    • Bradley, S. R.; Standaert, D. G.; Rhodes, K. J.; Rees, H. D.; Testa, C. M.; Levey, A. I.; Conn, P. J. Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia. J. Comp. Neurol., 1999, 407 (1), 33-46.
    • (1999) J. Comp. Neurol. , vol.407 , Issue.1 , pp. 33-46
    • Bradley, S.R.1    Standaert, D.G.2    Rhodes, K.J.3    Rees, H.D.4    Testa, C.M.5    Levey, A.I.6    Conn, P.J.7
  • 254
    • 0042626528 scopus 로고    scopus 로고
    • Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse
    • Valenti, O.; Marino, M. J.; Wittmann, M.; Lis, E.; DiLella, A. G.; Kinney, G. G.; Conn, P. J. Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse. J. Neurosci., 2003, 23 (18), 7218-7226.
    • (2003) J. Neurosci. , vol.23 , Issue.18 , pp. 7218-7226
    • Valenti, O.1    Marino, M.J.2    Wittmann, M.3    Lis, E.4    Dilella, A.G.5    Kinney, G.G.6    Conn, P.J.7
  • 255
    • 34250830873 scopus 로고    scopus 로고
    • Targeting group III metabotropic glutamate receptors produces complex behavioral effects in rodent models of Parkinson's disease
    • Lopez, S.; Turle-Lorenzo, N.; Acher, F.; De, L. E.; Mele, A.; Amalric, M. Targeting group III metabotropic glutamate receptors produces complex behavioral effects in rodent models of Parkinson's disease. J. Neurosci., 2007, 27 (25), 6701-6711.
    • (2007) J. Neurosci. , vol.27 , Issue.25 , pp. 6701-6711
    • Lopez, S.1    Turle-Lorenzo, N.2    Acher, F.3    De, L.E.4    Mele, A.5    Amalric, M.6
  • 257
    • 70349695699 scopus 로고    scopus 로고
    • Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism
    • Beurrier, C.; Lopez, S.; Revy, D.; Selvam, C.; Goudet, C.; Lherondel, M.; Gubellini, P.; Kerkerian-LeGoff, L.; Acher, F.; Pin, J. P.; Amalric, M. Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism. FASEB J., 2009, 23 (10), 3619-3628.
    • (2009) FASEB J , vol.23 , Issue.10 , pp. 3619-3628
    • Beurrier, C.1    Lopez, S.2    Revy, D.3    Selvam, C.4    Goudet, C.5    Lherondel, M.6    Gubellini, P.7    Kerkerian-Legoff, L.8    Acher, F.9    Pin, J.P.10    Amalric, M.11
  • 258
    • 33646446045 scopus 로고    scopus 로고
    • Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism
    • Jiang, Q.; Yan, Z.; Feng, J. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J. Neurosci., 2006, 26 (16), 4318-4328.
    • (2006) J. Neurosci. , vol.26 , Issue.16 , pp. 4318-4328
    • Jiang, Q.1    Yan, Z.2    Feng, J.3
  • 259
    • 19444377720 scopus 로고    scopus 로고
    • Group III metabotropic glutamate-receptor-mediated modulation of excitatory transmission in rodent substantia nigra pars compacta dopamine neurons
    • Valenti, O.; Mannaioni, G.; Seabrook, G. R.; Conn, P. J.; Marino, M. J. Group III metabotropic glutamate-receptor-mediated modulation of excitatory transmission in rodent substantia nigra pars compacta dopamine neurons. J. Pharmacol. Exp. Ther., 2005, 313 (3), 1296-1304.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , Issue.3 , pp. 1296-1304
    • Valenti, O.1    Mannaioni, G.2    Seabrook, G.R.3    Conn, P.J.4    Marino, M.J.5
  • 260
    • 77249085779 scopus 로고    scopus 로고
    • Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease
    • Greco, B.; Lopez, S.; Van der Putten, H. P.; Flor, P. J.; Amalric, M. Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease. J. Pharmacol. Exper. Therap., 2010, 332 (3), 1064-1071.
    • (2010) J. Pharmacol. Exper. Therap. , vol.332 , Issue.3 , pp. 1064-1071
    • Greco, B.1    Lopez, S.2    van der Putten, H.P.3    Flor, P.J.4    Amalric, M.5
  • 261
    • 0036591683 scopus 로고    scopus 로고
    • The fragile X premutation: Into the phenotypic fold
    • Hagerman, R. J.; Hagerman, P. J. The fragile X premutation: into the phenotypic fold. Curr. Opin. Genet Dev., 2002, 12 (3), 278-283.
    • (2002) Curr. Opin. Genet Dev. , vol.12 , Issue.3 , pp. 278-283
    • Hagerman, R.J.1    Hagerman, P.J.2
  • 262
    • 0035746538 scopus 로고    scopus 로고
    • FMR1 and the fragile X syndrome: Human genome epidemiology review
    • Crawford, D. C.; Acuna, J. M.; Sherman, S. L. FMR1 and the fragile X syndrome: human genome epidemiology review. Genet Med., 2001, 3 (5), 359-371.
    • (2001) Genet Med , vol.3 , Issue.5 , pp. 359-371
    • Crawford, D.C.1    Acuna, J.M.2    Sherman, S.L.3
  • 263
    • 70350022707 scopus 로고    scopus 로고
    • Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities
    • Schütt, J.; Falley, K.; Richter, D.; Kreienkamp, H. J.; Kindler, S. Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities. J. Biol. Chem., 2009, 284 (38), 25479-25487.
    • (2009) J. Biol. Chem. , vol.284 , Issue.38 , pp. 25479-25487
    • Schütt, J.1    Falley, K.2    Richter, D.3    Kreienkamp, H.J.4    Kindler, S.5
  • 264
    • 77952430888 scopus 로고    scopus 로고
    • Signals, synapses, and synthesis: How new proteins control plasticity
    • Zukin, R. S.; Richter, J. D.; Bagni, C. Signals, synapses, and synthesis: how new proteins control plasticity. Front. Neural. Circuits, 2009, 3, 14.
    • (2009) Front. Neural. Circuits. , vol.3 , pp. 14
    • Zukin, R.S.1    Richter, J.D.2    Bagni, C.3
  • 265
    • 0003187009 scopus 로고
    • The Dutch-Belgian Fragile X Consortium Fmr1 knockout mice: A model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium
    • The Dutch-Belgian Fragile X Consortium Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium. Cell, 1994, 78 (1), 23-33.
    • (1994) Cell , vol.78 , Issue.1 , pp. 23-33
  • 267
    • 24344457816 scopus 로고    scopus 로고
    • Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP
    • Yan, Q. J.; Rammal, M.; Tranfaglia, M.; Bauchwitz, R. P. Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP. Neuropharmacology, 2005, 49 (7), 1053-1066.
    • (2005) Neuropharmacology , vol.49 , Issue.7 , pp. 1053-1066
    • Yan, Q.J.1    Rammal, M.2    Tranfaglia, M.3    Bauchwitz, R.P.4
  • 268
    • 26044460532 scopus 로고    scopus 로고
    • A null mutation for Fmr1 in female mice: Effects on regional cerebral metabolic rate for glucose and relationship to behavior
    • Qin, M.; Kang, J.; Smith, C. B. A null mutation for Fmr1 in female mice: effects on regional cerebral metabolic rate for glucose and relationship to behavior. Neuroscience, 2005, 135 (3), 999-1009.
    • (2005) Neuroscience , vol.135 , Issue.3 , pp. 999-1009
    • Qin, M.1    Kang, J.2    Smith, C.B.3
  • 269
    • 0037180564 scopus 로고    scopus 로고
    • Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation
    • Qin, M.; Kang, J.; Smith, C. B. Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation. Proc. Natl. Acad Sci. USA, 2002, 99 (24), 15758-15763.
    • (2002) Proc. Natl. Acad Sci. USA , vol.99 , Issue.24 , pp. 15758-15763
    • Qin, M.1    Kang, J.2    Smith, C.B.3
  • 270
    • 31444443968 scopus 로고    scopus 로고
    • Social behavior deficits in the Fmr1 mutant mouse
    • Mineur, Y. S.; Huynh, L. X.; Crusio, W. E. Social behavior deficits in the Fmr1 mutant mouse. Behav. Brain Res., 2006, 168 (1), 172-175.
    • (2006) Behav. Brain Res. , vol.168 , Issue.1 , pp. 172-175
    • Mineur, Y.S.1    Huynh, L.X.2    Crusio, W.E.3
  • 271
    • 26444548563 scopus 로고    scopus 로고
    • Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome
    • Spencer, C. M.; Alekseyenko, O.; Serysheva, E.; Yuva-Paylor, L. A.; Paylor, R. Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome. Genes Brain Behav., 2005, 4 (7), 420-430.
    • (2005) Genes Brain Behav , vol.4 , Issue.7 , pp. 420-430
    • Spencer, C.M.1    Alekseyenko, O.2    Serysheva, E.3    Yuva-Paylor, L.A.4    Paylor, R.5
  • 273
    • 0025720084 scopus 로고
    • Analysis of neocortex in three males with the fragile X syndrome
    • Hinton, V. J.; Brown, W. T.; Wisniewski, K.; Rudelli, R. D. Analysis of neocortex in three males with the fragile X syndrome. Am. J. Med. Genet, 1991, 41 (3), 289-294.
    • (1991) Am. J. Med. Genet. , vol.41 , Issue.3 , pp. 289-294
    • Hinton, V.J.1    Brown, W.T.2    Wisniewski, K.3    Rudelli, R.D.4
  • 275
    • 33746892681 scopus 로고    scopus 로고
    • Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines
    • Grossman, A. W.; Elisseou, N. M.; McKinney, B. C.; Greenough, W. T. Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines. Brain Res., 2006, 1084 (1), 158-164.
    • (2006) Brain Res , vol.1084 , Issue.1 , pp. 158-164
    • Grossman, A.W.1    Elisseou, N.M.2    McKinney, B.C.3    Greenough, W.T.4
  • 276
    • 20044388939 scopus 로고    scopus 로고
    • Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome
    • Galvez, R.; Greenough, W. T. Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. Am. J. Med. Genet, A., 2005, 135 (2), 155-160.
    • (2005) Am. J. Med. Genet, A. , vol.135 , Issue.2 , pp. 155-160
    • Galvez, R.1    Greenough, W.T.2
  • 278
    • 17844372504 scopus 로고    scopus 로고
    • From mRNP trafficking to spine dysmorphogenesis: The roots of fragile X syndrome
    • Bagni, C.; Greenough, W. T. From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat. Rev. Neurosci., 2005, 6 (5), 376-387.
    • (2005) Nat. Rev. Neurosci. , vol.6 , Issue.5 , pp. 376-387
    • Bagni, C.1    Greenough, W.T.2
  • 279
    • 44549086670 scopus 로고    scopus 로고
    • Genes, plasticity and mental retardation
    • Vaillend, C.; Poirier, R.; Laroche, S. Genes, plasticity and mental retardation. Behav. Brain Res., 2008, 192 (1), 88-105.
    • (2008) Behav. Brain Res. , vol.192 , Issue.1 , pp. 88-105
    • Vaillend, C.1    Poirier, R.2    Laroche, S.3
  • 280
    • 3042647610 scopus 로고    scopus 로고
    • The mGluR theory of fragile X mental retardation
    • Bear, M. F.; Huber, K. M.; Warren, S. T. The mGluR theory of fragile X mental retardation. Trends Neurosci., 2004, 27 (7), 370-377.
    • (2004) Trends Neurosci , vol.27 , Issue.7 , pp. 370-377
    • Bear, M.F.1    Huber, K.M.2    Warren, S.T.3
  • 281
    • 0037188502 scopus 로고    scopus 로고
    • Altered synaptic plasticity in a mouse model of fragile X mental retardation
    • Huber, K. M.; Gallagher, S. M.; Warren, S. T.; Bear, M. F. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl. Acad Sci. USA, 2002, 99 (11), 7746-7750.
    • (2002) Proc. Natl. Acad Sci. USA , vol.99 , Issue.11 , pp. 7746-7750
    • Huber, K.M.1    Gallagher, S.M.2    Warren, S.T.3    Bear, M.F.4
  • 283
    • 68649093278 scopus 로고    scopus 로고
    • Protein translation in synaptic plasticity: MGluR-LTD, Fragile X
    • Waung, M. W.; Huber, K. M. Protein translation in synaptic plasticity: mGluR-LTD, Fragile X. Curr. Opin. Neurobiol., 2009, 19 (3), 319-326.
    • (2009) Curr. Opin. Neurobiol. , vol.19 , Issue.3 , pp. 319-326
    • Waung, M.W.1    Huber, K.M.2
  • 284
    • 33646194363 scopus 로고    scopus 로고
    • Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome
    • Nosyreva, E. D.; Huber, K. M. Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome. J. Neurophysiol., 2006, 95 (5), 3291-3295.
    • (2006) J. Neurophysiol. , vol.95 , Issue.5 , pp. 3291-3295
    • Nosyreva, E.D.1    Huber, K.M.2
  • 286
    • 71549145629 scopus 로고    scopus 로고
    • Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome
    • Yuskaitis, C. J.; Mines, M. A.; King, M. K.; Sweatt, J. D.; Miller, C. A.; Jope, R. S. Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome. Biochem. Pharmacol., 2010, 79 (4), 632-646.
    • (2010) Biochem. Pharmacol. , vol.79 , Issue.4 , pp. 632-646
    • Yuskaitis, C.J.1    Mines, M.A.2    King, M.K.3    Sweatt, J.D.4    Miller, C.A.5    Jope, R.S.6
  • 289
    • 33751353757 scopus 로고    scopus 로고
    • Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome
    • Tucker, B.; Richards, R. I.; Lardelli, M. Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome. Hum. Mol. Genet., 2006, 15 (23), 3446-3458.
    • (2006) Hum. Mol. Genet. , vol.15 , Issue.23 , pp. 3446-3458
    • Tucker, B.1    Richards, R.I.2    Lardelli, M.3
  • 293
    • 16444361969 scopus 로고    scopus 로고
    • Effects of mGlu1 and mGlu5 receptor antagonists on negatively reinforced learning
    • Gravius, A.; Pietraszek, M.; Schafer, D.; Schmidt, W. J.; Danysz, W. Effects of mGlu1 and mGlu5 receptor antagonists on negatively reinforced learning. Behav. Pharmacol., 2005, 16 (2), 113-121.
    • (2005) Behav. Pharmacol. , vol.16 , Issue.2 , pp. 113-121
    • Gravius, A.1    Pietraszek, M.2    Schafer, D.3    Schmidt, W.J.4    Danysz, W.5
  • 295
    • 23944490213 scopus 로고    scopus 로고
    • Recent advances in fragile X: A model for autism and neurodegeneration
    • Hagerman, R. J.; Ono, M. Y.; Hagerman, P. J. Recent advances in fragile X: a model for autism and neurodegeneration. Curr. Opin. Psychiatry, 2005, 18 (5), 490-496.
    • (2005) Curr. Opin. Psychiatry. , vol.18 , Issue.5 , pp. 490-496
    • Hagerman, R.J.1    Ono, M.Y.2    Hagerman, P.J.3
  • 296
    • 76749128438 scopus 로고    scopus 로고
    • Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP
    • Silverman, J. L.; Tolu, S. S.; Barkan, C. L.; Crawley, J. N. Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP. Neuropsychopharmacology, 2010, 35 (4), 976-989.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.4 , pp. 976-989
    • Silverman, J.L.1    Tolu, S.S.2    Barkan, C.L.3    Crawley, J.N.4
  • 297
    • 23144446194 scopus 로고    scopus 로고
    • Molecular targets and therapeutic strategies in Huntington's disease
    • Rego, A. C.; de Almeida, L. P. Molecular targets and therapeutic strategies in Huntington's disease. Curr. Drug Targets CNS Neurol. Disord., 2005, 4 (4), 361-381.
    • (2005) Curr. Drug Targets CNS Neurol. Disord. , vol.4 , Issue.4 , pp. 361-381
    • Rego, A.C.1    de Almeida, L.P.2
  • 298
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • Li, S. H.; Li, X. J. Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet., 2004, 20 (3), 146-154.
    • (2004) Trends Genet , vol.20 , Issue.3 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 300
    • 0029943742 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in Huntington's disease: Evidence in favour of the glutamate excitotoxic theory
    • Taylor-Robinson, S. D.; Weeks, R. A.; Bryant, D. J.; Sargentoni, J.; Marcus, C. D.; Harding, A. E.; Brooks, D. J. Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory. Mov. Disord., 1996, 11 (2), 167-173.
    • (1996) Mov. Disord. , vol.11 , Issue.2 , pp. 167-173
    • Taylor-Robinson, S.D.1    Weeks, R.A.2    Bryant, D.J.3    Sargentoni, J.4    Marcus, C.D.5    Harding, A.E.6    Brooks, D.J.7
  • 301
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
    • Fan, M. M.; Raymond, L. A. N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog. Neurobiol., 2007, 81 (5-6), 272-293.
    • (2007) Prog. Neurobiol. , vol.81 , Issue.5-6 , pp. 272-293
    • Fan, M.M.1    Raymond, L.A.2
  • 303
    • 27144523294 scopus 로고    scopus 로고
    • Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin
    • Anborgh, P. H.; Godin, C.; Pampillo, M.; Dhami, G. K.; Dale, L. B.; Cregan, S. P.; Truant, R.; Ferguson, S. S. Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. J. Biol. Chem., 2005, 280 (41), 34840-34848.
    • (2005) J. Biol. Chem. , vol.280 , Issue.41 , pp. 34840-34848
    • Anborgh, P.H.1    Godin, C.2    Pampillo, M.3    Dhami, G.K.4    Dale, L.B.5    Cregan, S.P.6    Truant, R.7    Ferguson, S.S.8
  • 304
    • 74849091009 scopus 로고    scopus 로고
    • Metabotropic glutamate receptormediated cell signaling pathways are altered in a mouse model of Huntington's disease
    • Ribeiro, F. M.; Paquet, M.; Ferreira, L. T.; Cregan, T.; Swan, P.; Cregan, S. P.; Ferguson, S. S. Metabotropic glutamate receptormediated cell signaling pathways are altered in a mouse model of Huntington's disease. J. Neurosci., 2010, 30 (1), 316-324.
    • (2010) J. Neurosci. , vol.30 , Issue.1 , pp. 316-324
    • Ribeiro, F.M.1    Paquet, M.2    Ferreira, L.T.3    Cregan, T.4    Swan, P.5    Cregan, S.P.6    Ferguson, S.S.7
  • 305
    • 0029561263 scopus 로고
    • Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3- hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions
    • Orlando, L. R.; Standaert, D. G.; Penney, J. B., Jr.; Young, A. B. Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3- hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neurosci. Lett., 1995, 202 (1-2), 109-112.
    • (1995) Neurosci. Lett. , vol.202 , Issue.1-2 , pp. 109-112
    • Orlando, L.R.1    Standaert, D.G.2    Penney Jr., J.B.3    Young, A.B.4
  • 306
    • 26844498655 scopus 로고    scopus 로고
    • The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies
    • Li, J. Y.; Popovic, N.; Brundin, P. The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies. Neuro. Rx., 2005, 2 (3), 447-464.
    • (2005) Neuro. Rx. , vol.2 , Issue.3 , pp. 447-464
    • Li, J.Y.1    Popovic, N.2    Brundin, P.3
  • 308
    • 0036345741 scopus 로고    scopus 로고
    • Impaired glutamate transport and glutamateglutamine cycling: Downstream effects of the Huntington mutation
    • Behrens, P. F.; Franz, P.; Woodman, B.; Lindenberg, K. S.; Landwehrmeyer, G. B. Impaired glutamate transport and glutamateglutamine cycling: downstream effects of the Huntington mutation. Brain, 2002, 125 (Pt 8), 1908-1922.
    • (2002) Brain , vol.125 , Issue.PART 8 , pp. 1908-1922
    • Behrens, P.F.1    Franz, P.2    Woodman, B.3    Lindenberg, K.S.4    Landwehrmeyer, G.B.5
  • 309
    • 4043164771 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease
    • Schiefer, J.; Sprunken, A.; Puls, C.; Luesse, H. G.; Milkereit, A.; Milkereit, E.; Johann, V.; Kosinski, C. M. The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease. Brain Res., 2004, 1019 (1-2), 246-254.
    • (2004) Brain Res , vol.1019 , Issue.1-2 , pp. 246-254
    • Schiefer, J.1    Sprunken, A.2    Puls, C.3    Luesse, H.G.4    Milkereit, A.5    Milkereit, E.6    Johann, V.7    Kosinski, C.M.8
  • 310
    • 0036652765 scopus 로고    scopus 로고
    • Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease
    • Schiefer, J.; Landwehrmeyer, G. B.; Luesse, H. G.; Sprunken, A.; Puls, C.; Milkereit, A.; Milkereit, E.; Kosinski, C. M. Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease. Mov. Disord., 2002, 17 (4), 748-757.
    • (2002) Mov. Disord. , vol.17 , Issue.4 , pp. 748-757
    • Schiefer, J.1    Landwehrmeyer, G.B.2    Luesse, H.G.3    Sprunken, A.4    Puls, C.5    Milkereit, A.6    Milkereit, E.7    Kosinski, C.M.8
  • 312
    • 0025899041 scopus 로고
    • Amyloid deposition as the central event in the aetiology of Alzheimer's disease
    • Hardy, J.; Allsop, D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol. Sci., 1991, 12 (10), 383-388.
    • (1991) Trends Pharmacol. Sci. , vol.12 , Issue.10 , pp. 383-388
    • Hardy, J.1    Allsop, D.2
  • 313
    • 0141483708 scopus 로고    scopus 로고
    • Glutamatergic systems in Alzheimer's disease
    • Francis, P. T. Glutamatergic systems in Alzheimer's disease. Int. J. Geriatr. Psychiatry, 2003, 18 (Suppl 1), S15-S21.
    • (2003) Int. J. Geriatr. Psychiatry. , vol.18 , Issue.SUPPL. 1
    • Francis, P.T.1
  • 315
    • 27744583133 scopus 로고    scopus 로고
    • Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes
    • Albasanz, J. L.; Dalfo, E.; Ferrer, I.; Martin, M. Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes. Neurobiol. Dis., 2005, 20 (3), 685-693.
    • (2005) Neurobiol. Dis. , vol.20 , Issue.3 , pp. 685-693
    • Albasanz, J.L.1    Dalfo, E.2    Ferrer, I.3    Martin, M.4
  • 316
    • 0029147583 scopus 로고
    • Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors
    • Lee, R. K.; Wurtman, R. J.; Cox, A. J.; Nitsch, R. M. Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc. Natl. Acad Sci. USA, 1995, 92 (17), 8083-8087.
    • (1995) Proc. Natl. Acad Sci. USA , vol.92 , Issue.17 , pp. 8083-8087
    • Lee, R.K.1    Wurtman, R.J.2    Cox, A.J.3    Nitsch, R.M.4
  • 317
    • 0032577677 scopus 로고    scopus 로고
    • Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons
    • Jolly-Tornetta, C.; Gao, Z. Y.; Lee, V. M.; Wolf, B. A. Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons. J. Biol. Chem., 1998, 273 (22), 14015-14021.
    • (1998) J. Biol. Chem. , vol.273 , Issue.22 , pp. 14015-14021
    • Jolly-Tornetta, C.1    Gao, Z.Y.2    Lee, V.M.3    Wolf, B.A.4
  • 322
    • 0028242970 scopus 로고
    • Requirement of metabotropic glutamate receptors for the generation of inflammationevoked hyperexcitability in rat spinal cord neurons
    • Neugebauer, V.; Lucke, T.; Schaible, H. G. Requirement of metabotropic glutamate receptors for the generation of inflammationevoked hyperexcitability in rat spinal cord neurons. Eur. J. Neurosci., 1994, 6 (7), 1179-1186.
    • (1994) Eur. J. Neurosci. , vol.6 , Issue.7 , pp. 1179-1186
    • Neugebauer, V.1    Lucke, T.2    Schaible, H.G.3
  • 324
    • 0033966692 scopus 로고    scopus 로고
    • Differential distribution of metabotropic glutamate receptor subtype mRNAs in the thalamus of the rat
    • Lourenco, N. F.; Schadrack, J.; Berthele, A.; Zieglgansberger, W.; Tolle, T. R.; Castro-Lopes, J. M. Differential distribution of metabotropic glutamate receptor subtype mRNAs in the thalamus of the rat. Brain Res., 2000, 854 (1-2), 93-105.
    • (2000) Brain Res , vol.854 , Issue.1-2 , pp. 93-105
    • Lourenco, N.F.1    Schadrack, J.2    Berthele, A.3    Zieglgansberger, W.4    Tolle, T.R.5    Castro-Lopes, J.M.6
  • 325
    • 0030777350 scopus 로고    scopus 로고
    • A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1 alpha metabotropic glutamate receptors
    • Petralia, R. S.; Wang, Y. X.; Singh, S.; Wu, C.; Shi, L.; Wei, J.; Wenthold, R. J. A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1 alpha metabotropic glutamate receptors. J. Chem. Neuroanat., 1997, 13 (2), 77-93.
    • (1997) J. Chem. Neuroanat. , vol.13 , Issue.2 , pp. 77-93
    • Petralia, R.S.1    Wang, Y.X.2    Singh, S.3    Wu, C.4    Shi, L.5    Wei, J.6    Wenthold, R.J.7
  • 327
    • 33845655591 scopus 로고    scopus 로고
    • The amygdala: Different pains, different mechanisms
    • Neugebauer, V. The amygdala: different pains, different mechanisms. Pain 2007, 127 (1-2), 1-2.
    • (2007) Pain , vol.127 , Issue.1-2 , pp. 1-2
    • Neugebauer, V.1
  • 328
    • 34447504918 scopus 로고    scopus 로고
    • Microglia: A newly discovered role in visceral hypersensitivity?
    • Saab, C. Y.; Wang, J.; Gu, C.; Garner, K. N.; Al-Chaer, E. D. Microglia: a newly discovered role in visceral hypersensitivity? Neuron. Glia. Biol., 2007, 2 (4), 271-277.
    • (2007) Neuron. Glia. Biol. , vol.2 , Issue.4 , pp. 271-277
    • Saab, C.Y.1    Wang, J.2    Gu, C.3    Garner, K.N.4    Al-Chaer, E.D.5
  • 329
    • 0034073487 scopus 로고    scopus 로고
    • Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission
    • Dolan, S.; Nolan, A. M. Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission. Neuropharmacology, 2000, 39 (7), 1132-1138.
    • (2000) Neuropharmacology , vol.39 , Issue.7 , pp. 1132-1138
    • Dolan, S.1    Nolan, A.M.2
  • 330
    • 0030444724 scopus 로고    scopus 로고
    • The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception
    • Fisher, K.; Coderre, T. J. The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. Pain, 1996, 68 (2-3), 255-263.
    • (1996) Pain , vol.68 , Issue.2-3 , pp. 255-263
    • Fisher, K.1    Coderre, T.J.2
  • 331
    • 0031663115 scopus 로고    scopus 로고
    • Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats
    • Fisher, K.; Fundytus, M. E.; Cahill, C. M.; Coderre, T. J. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain, 1998, 77 (1), 59-66.
    • (1998) Pain , vol.77 , Issue.1 , pp. 59-66
    • Fisher, K.1    Fundytus, M.E.2    Cahill, C.M.3    Coderre, T.J.4
  • 332
    • 0037178637 scopus 로고    scopus 로고
    • Activation of spinal group I metabotropic glutamate receptors in rats evokes local glutamate release and spontaneous nociceptive behaviors: Effects of 2-methyl-6-(phenylethynyl)-pyridine pretreatment
    • Lorrain, D. S.; Correa, L.; Anderson, J.; Varney, M. Activation of spinal group I metabotropic glutamate receptors in rats evokes local glutamate release and spontaneous nociceptive behaviors: effects of 2-methyl-6-(phenylethynyl)-pyridine pretreatment. Neurosci. Lett., 2002, 327 (3), 198-202.
    • (2002) Neurosci. Lett. , vol.327 , Issue.3 , pp. 198-202
    • Lorrain, D.S.1    Correa, L.2    Anderson, J.3    Varney, M.4
  • 333
    • 0032498802 scopus 로고    scopus 로고
    • In vivo antinociceptive activity of anti-rat mGluR1 and mGluR5 antibodies in rats
    • Fundytus, M. E.; Fisher, K.; Dray, A.; Henry, J. L.; Coderre, T. J. In vivo antinociceptive activity of anti-rat mGluR1 and mGluR5 antibodies in rats. Neuroreport, 1998, 9 (4), 731-735.
    • (1998) Neuroreport , vol.9 , Issue.4 , pp. 731-735
    • Fundytus, M.E.1    Fisher, K.2    Dray, A.3    Henry, J.L.4    Coderre, T.J.5
  • 334
    • 0035150239 scopus 로고    scopus 로고
    • Knockdown of spinal metabotropic glutamate receptor 1 (mGluR(1)) alleviates pain and restores opioid efficacy after nerve injury in rats
    • Fundytus, M. E.; Yashpal, K.; Chabot, J. G.; Osborne, M. G.; Lefebvre, C. D.; Dray, A.; Henry, J. L.; Coderre, T. J. Knockdown of spinal metabotropic glutamate receptor 1 (mGluR(1)) alleviates pain and restores opioid efficacy after nerve injury in rats. Br. J. Pharmacol., 2001, 132 (1), 354-367.
    • (2001) Br. J. Pharmacol. , vol.132 , Issue.1 , pp. 354-367
    • Fundytus, M.E.1    Yashpal, K.2    Chabot, J.G.3    Osborne, M.G.4    Lefebvre, C.D.5    Dray, A.6    Henry, J.L.7    Coderre, T.J.8
  • 335
    • 0035996507 scopus 로고    scopus 로고
    • Antisense oligonucleotide knockdown of mGluR1 alleviates hyperalgesia and allodynia associated with chronic inflammation
    • Fundytus, M. E.; Osborne, M. G.; Henry, J. L.; Coderre, T. J.; Dray, A. Antisense oligonucleotide knockdown of mGluR1 alleviates hyperalgesia and allodynia associated with chronic inflammation. Pharmacol. Biochem. Behav., 2002, 73 (2), 401-410.
    • (2002) Pharmacol. Biochem. Behav. , vol.73 , Issue.2 , pp. 401-410
    • Fundytus, M.E.1    Osborne, M.G.2    Henry, J.L.3    Coderre, T.J.4    Dray, A.5
  • 336
    • 0142070816 scopus 로고    scopus 로고
    • Antisense knockdown of spinal-mGluR1 reduces the sustained phase of formalin-induced nociceptive responses
    • Noda, K.; Anzai, T.; Ogata, M.; Akita, H.; Ogura, T.; Saji, M. Antisense knockdown of spinal-mGluR1 reduces the sustained phase of formalin-induced nociceptive responses. Brain Res., 2003, 987 (2), 194-200.
    • (2003) Brain Res , vol.987 , Issue.2 , pp. 194-200
    • Noda, K.1    Anzai, T.2    Ogata, M.3    Akita, H.4    Ogura, T.5    Saji, M.6
  • 338
    • 4344648261 scopus 로고    scopus 로고
    • Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation
    • Adwanikar, H.; Karim, F.; Gereau, R. W. Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation. Pain, 2004, 111 (1-2), 125-135.
    • (2004) Pain , vol.111 , Issue.1-2 , pp. 125-135
    • Adwanikar, H.1    Karim, F.2    Gereau, R.W.3
  • 339
    • 0031901499 scopus 로고    scopus 로고
    • Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4- carboxy-phenylglycine
    • Salt, T. E.; Turner, J. P. Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4- carboxy-phenylglycine. Neuroscience, 1998, 85 (3), 655-658.
    • (1998) Neuroscience , vol.85 , Issue.3 , pp. 655-658
    • Salt, T.E.1    Turner, J.P.2
  • 340
    • 11144298072 scopus 로고    scopus 로고
    • mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain
    • Han, J. S.; Neugebauer, V. mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain. Pain, 2005, 113 (1-2), 211-222.
    • (2005) Pain , vol.113 , Issue.1-2 , pp. 211-222
    • Han, J.S.1    Neugebauer, V.2
  • 342
    • 0037731410 scopus 로고    scopus 로고
    • [3H]R214127: A novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists
    • Lavreysen, H.; Janssen, C.; Bischoff, F.; Langlois, X.; Leysen, J. E.; Lesage, A. S. [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. Mol. Pharmacol., 2003, 63 (5), 1082-1093.
    • (2003) Mol. Pharmacol. , vol.63 , Issue.5 , pp. 1082-1093
    • Lavreysen, H.1    Janssen, C.2    Bischoff, F.3    Langlois, X.4    Leysen, J.E.5    Lesage, A.S.6
  • 344
    • 0036137084 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation
    • Zhang, L.; Lu, Y.; Chen, Y.; Westlund, K. N. Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation. J. Pharmacol. Exp. Ther., 2002, 300 (1), 149-156.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , Issue.1 , pp. 149-156
    • Zhang, L.1    Lu, Y.2    Chen, Y.3    Westlund, K.N.4
  • 345
    • 0032867635 scopus 로고    scopus 로고
    • Evaluation of agonists and antagonists acting at Group I metabotropic glutamate receptors in the thalamus in vivo
    • Salt, T. E.; Turner, J. P.; Kingston, A. E. Evaluation of agonists and antagonists acting at Group I metabotropic glutamate receptors in the thalamus in vivo. Neuropharmacology, 1999, 38 (10), 1505-1510.
    • (1999) Neuropharmacology , vol.38 , Issue.10 , pp. 1505-1510
    • Salt, T.E.1    Turner, J.P.2    Kingston, A.E.3
  • 346
    • 33947432459 scopus 로고    scopus 로고
    • The peripheral role of group I metabotropic glutamate receptors on nociceptive behaviors in rats with knee joint inflammation
    • Lee, K. S.; Kim, J.; Yoon, Y. W.; Lee, M. G.; Hong, S. K.; Han, H. C. The peripheral role of group I metabotropic glutamate receptors on nociceptive behaviors in rats with knee joint inflammation. Neurosci. Lett., 2007, 416 (2), 123-127.
    • (2007) Neurosci. Lett. , vol.416 , Issue.2 , pp. 123-127
    • Lee, K.S.1    Kim, J.2    Yoon, Y.W.3    Lee, M.G.4    Hong, S.K.5    Han, H.C.6
  • 350
    • 0035049968 scopus 로고    scopus 로고
    • Actions of the systemically active metabotropic glutamate antagonist MPEP on sensory responses of thalamic neurones
    • Binns, K. E.; Salt, T. E. Actions of the systemically active metabotropic glutamate antagonist MPEP on sensory responses of thalamic neurones. Neuropharmacology, 2001, 40 (5), 639-644.
    • (2001) Neuropharmacology , vol.40 , Issue.5 , pp. 639-644
    • Binns, K.E.1    Salt, T.E.2
  • 351
    • 0034613452 scopus 로고    scopus 로고
    • Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats
    • Dogrul, A.; Ossipov, M. H.; Lai, J.; Malan, T. P., Jr.; Porreca, F. Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats. Neurosci. Lett., 2000, 292 (2), 115-118.
    • (2000) Neurosci. Lett. , vol.292 , Issue.2 , pp. 115-118
    • Dogrul, A.1    Ossipov, M.H.2    Lai, J.3    Malan Jr., T.P.4    Porreca, F.5
  • 353
    • 0035134263 scopus 로고    scopus 로고
    • Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception
    • V
    • Palazzo, E.; Marabese, I.; de, N., V; Oliva, P.; Rossi, F.; Berrino, L.; Rossi, F.; Maione, S. Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception. Neuropharmacology, 2001, 40 (3), 319-326.
    • (2001) Neuropharmacology , vol.40 , Issue.3 , pp. 319-326
    • Palazzo, E.1    Marabese, I.2    De, N.3    Oliva, P.4    Rossi, F.5    Berrino, L.6    Rossi, F.7    Maione, S.8
  • 354
    • 84934441155 scopus 로고    scopus 로고
    • NAAG as a neurotransmitter
    • Wroblewska, B. NAAG as a neurotransmitter. Adv. Exp. Med. Biol., 2006, 576, 317-325.
    • (2006) Adv. Exp. Med. Biol. , vol.576 , pp. 317-325
    • Wroblewska, B.1
  • 356
    • 3242750466 scopus 로고    scopus 로고
    • Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model
    • Yamamoto, T.; Hirasawa, S.; Wroblewska, B.; Grajkowska, E.; Zhou, J.; Kozikowski, A.; Wroblewski, J.; Neale, J. H. Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model. Eur. J. Neurosci., 2004, 20 (2), 483-494.
    • (2004) Eur. J. Neurosci. , vol.20 , Issue.2 , pp. 483-494
    • Yamamoto, T.1    Hirasawa, S.2    Wroblewska, B.3    Grajkowska, E.4    Zhou, J.5    Kozikowski, A.6    Wroblewski, J.7    Neale, J.H.8
  • 357
    • 0036710924 scopus 로고    scopus 로고
    • Behavioral evidence supporting a differential role for spinal group I and II metabotropic glutamate receptors in inflammatory hyperalgesia in sheep
    • Dolan, S.; Nolan, A. M. Behavioral evidence supporting a differential role for spinal group I and II metabotropic glutamate receptors in inflammatory hyperalgesia in sheep. Neuropharmacology, 2002, 43 (3), 319-326.
    • (2002) Neuropharmacology , vol.43 , Issue.3 , pp. 319-326
    • Dolan, S.1    Nolan, A.M.2
  • 358
    • 33749514629 scopus 로고    scopus 로고
    • Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain
    • Li, W.; Neugebauer, V. Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain. J. Neurophysiol., 2006, 96 (4), 1803-1815.
    • (2006) J. Neurophysiol. , vol.96 , Issue.4 , pp. 1803-1815
    • Li, W.1    Neugebauer, V.2
  • 359
    • 0033635528 scopus 로고    scopus 로고
    • Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells
    • Neugebauer, V.; Chen, P. S.; Willis, W. D. Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells. J. Neurophysiol., 2000, 84 (6), 2998-3009.
    • (2000) J. Neurophysiol. , vol.84 , Issue.6 , pp. 2998-3009
    • Neugebauer, V.1    Chen, P.S.2    Willis, W.D.3
  • 360
    • 0036198356 scopus 로고    scopus 로고
    • Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo
    • Sharpe, E. F.; Kingston, A. E.; Lodge, D.; Monn, J. A.; Headley, P. M. Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo. Br. J. Pharmacol., 2002, 135 (5), 1255-1262.
    • (2002) Br. J. Pharmacol. , vol.135 , Issue.5 , pp. 1255-1262
    • Sharpe, E.F.1    Kingston, A.E.2    Lodge, D.3    Monn, J.A.4    Headley, P.M.5
  • 361
    • 0035996526 scopus 로고    scopus 로고
    • Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats
    • Simmons, R. M.; Webster, A. A.; Kalra, A. B.; Iyengar, S. Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats. Pharmacol. Biochem. Behav., 2002, 73 (2), 419-427.
    • (2002) Pharmacol. Biochem. Behav. , vol.73 , Issue.2 , pp. 419-427
    • Simmons, R.M.1    Webster, A.A.2    Kalra, A.B.3    Iyengar, S.4
  • 362
    • 0001050064 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor involvement in models of acute and persistent pain: Prospects for the development of novel analgesics
    • Varney, M. A.; Gereau, R. W. Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics. Curr. Drug Targets CNS Neurol. Disord., 2002, 1 (3), 283-296.
    • (2002) Curr. Drug Targets CNS Neurol. Disord. , vol.1 , Issue.3 , pp. 283-296
    • Varney, M.A.1    Gereau, R.W.2
  • 363
    • 0345167994 scopus 로고    scopus 로고
    • Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation
    • Yang, D.; Gereau, R. W. Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation. Pain, 2003, 106 (3), 411-417.
    • (2003) Pain , vol.106 , Issue.3 , pp. 411-417
    • Yang, D.1    Gereau, R.W.2
  • 364
    • 0036085243 scopus 로고    scopus 로고
    • Peripheral metabotropic glutamate receptors as drug targets for pain relief
    • Neugebauer, V.; Carlton, S. M. Peripheral metabotropic glutamate receptors as drug targets for pain relief. Expert Opin. Ther. Targets, 2002, 6 (3), 349-361.
    • (2002) Expert Opin. Ther. Targets. , vol.6 , Issue.3 , pp. 349-361
    • Neugebauer, V.1    Carlton, S.M.2
  • 365
    • 23644440111 scopus 로고    scopus 로고
    • Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing
    • Jones, C. K.; Eberle, E. L.; Peters, S. C.; Monn, J. A.; Shannon, H. E. Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing. Neuropharmacology, 2005, 49 Suppl 1, 206-218.
    • (2005) Neuropharmacology , vol.49 , Issue.SUPPL. 1 , pp. 206-218
    • Jones, C.K.1    Eberle, E.L.2    Peters, S.C.3    Monn, J.A.4    Shannon, H.E.5
  • 366
    • 11844301325 scopus 로고    scopus 로고
    • Distinct roles of group III metabotropic glutamate receptors in control of nociception and dorsal horn neurons in normal and nerve-injured Rats
    • Chen, S. R.; Pan, H. L. Distinct roles of group III metabotropic glutamate receptors in control of nociception and dorsal horn neurons in normal and nerve-injured Rats. J. Pharmacol. Exp. Ther., 2005, 312 (1), 120-126.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , Issue.1 , pp. 120-126
    • Chen, S.R.1    Pan, H.L.2
  • 367
    • 44949177323 scopus 로고    scopus 로고
    • Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain
    • Goudet, C.; Chapuy, E.; Alloui, A.; Acher, F.; Pin, J. P.; Eschalier, A. Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain. Pain, 2008, 137 (1), 112-124.
    • (2008) Pain , vol.137 , Issue.1 , pp. 112-124
    • Goudet, C.1    Chapuy, E.2    Alloui, A.3    Acher, F.4    Pin, J.P.5    Eschalier, A.6
  • 368
    • 1842664364 scopus 로고    scopus 로고
    • Enhanced group III mGluRmediated inhibition of pain-related synaptic plasticity in the amygdala
    • Han, J. S.; Bird, G. C.; Neugebauer, V. Enhanced group III mGluRmediated inhibition of pain-related synaptic plasticity in the amygdala. Neuropharmacology, 2004, 46 (7), 918-926.
    • (2004) Neuropharmacology , vol.46 , Issue.7 , pp. 918-926
    • Han, J.S.1    Bird, G.C.2    Neugebauer, V.3
  • 369
    • 49949087048 scopus 로고    scopus 로고
    • Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors
    • Palazzo, E.; Fu, Y.; Ji, G.; Maione, S.; Neugebauer, V. Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors. Neuropharmacology, 2008, 55 (4), 537-545.
    • (2008) Neuropharmacology , vol.55 , Issue.4 , pp. 537-545
    • Palazzo, E.1    Fu, Y.2    Ji, G.3    Maione, S.4    Neugebauer, V.5
  • 370
    • 0029592665 scopus 로고
    • Glutamate, GABA and epilepsy
    • Bradford, H. F. Glutamate, GABA and epilepsy. Prog. Neurobiol., 1995, 47 (6), 477-511.
    • (1995) Prog. Neurobiol. , vol.47 , Issue.6 , pp. 477-511
    • Bradford, H.F.1
  • 371
    • 0030323594 scopus 로고    scopus 로고
    • Role of glutamate and aspartate in epileptogenesis; contribution of microdialysis studies in animal and man
    • Chapman, A. G.; Elwes, R. D.; Millan, M. H.; Polkey, C. E.; Meldrum, B. S. Role of glutamate and aspartate in epileptogenesis; contribution of microdialysis studies in animal and man. Epilepsy, Res. Suppl., 1996, 12, 239-246.
    • (1996) Epilepsy, Res. Suppl. , vol.12 , pp. 239-246
    • Chapman, A.G.1    Elwes, R.D.2    Millan, M.H.3    Polkey, C.E.4    Meldrum, B.S.5
  • 372
    • 0034019756 scopus 로고    scopus 로고
    • Glutamate and epilepsy
    • Chapman, A. G. Glutamate and epilepsy. J. Nutr., 2000, 130 (4S Suppl), 1043S-1045S.
    • (2000) J. Nutr. , vol.130 , Issue.4 S SUPPL.
    • Chapman, A.G.1
  • 373
    • 0026297017 scopus 로고
    • Excitatory amino acids in epilepsy and novel anti-epileptic drugs
    • Chapman, A.; Meldrum, B. Excitatory amino acids in epilepsy and novel anti-epileptic drugs. Epilepsy Res. Suppl., 1991, 3, 39-48.
    • (1991) Epilepsy Res. Suppl. , vol.3 , pp. 39-48
    • Chapman, A.1    Meldrum, B.2
  • 374
    • 0026298759 scopus 로고
    • Excitatory amino acid transmitters in epilepsy
    • Meldrum, B. S. Excitatory amino acid transmitters in epilepsy. Epilepsia, 1991, 32 Suppl 2, S1-S3.
    • (1991) Epilepsia , vol.32 , Issue.SUPPL. 2
    • Meldrum, B.S.1
  • 375
    • 0026644603 scopus 로고
    • Excitatory amino acids in epilepsy and potential novel therapies
    • Meldrum, B. S. Excitatory amino acids in epilepsy and potential novel therapies. Epilepsy Res., 1992, 12 (2), 189-196.
    • (1992) Epilepsy Res , vol.12 , Issue.2 , pp. 189-196
    • Meldrum, B.S.1
  • 376
    • 30344467530 scopus 로고    scopus 로고
    • Up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients
    • Notenboom, R. G.; Hampson, D. R.; Jansen, G. H.; van Rijen, P. C.; van Veelen, C. W.; van, N. O.; de Graan, P. N. Up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients. Brain, 2006, 129 (Pt 1), 96-107.
    • (2006) Brain , vol.129 , Issue.PART 1 , pp. 96-107
    • Notenboom, R.G.1    Hampson, D.R.2    Jansen, G.H.3    van Rijen, P.C.4    van Veelen, C.W.5    Van, N.O.6    de Graan, P.N.7
  • 377
    • 0037630058 scopus 로고    scopus 로고
    • Expression and cell distribution of group I and group II metabotropic glutamate receptor subtypes in taylor-type focal cortical dysplasia
    • Aronica, E.; Gorter, J. A.; Jansen, G. H.; van Veelen, C. W.; van Rijen, P. C.; Ramkema, M.; Troost, D. Expression and cell distribution of group I and group II metabotropic glutamate receptor subtypes in taylor-type focal cortical dysplasia. Epilepsia, 2003, 44 (6), 785-795.
    • (2003) Epilepsia , vol.44 , Issue.6 , pp. 785-795
    • Aronica, E.1    Gorter, J.A.2    Jansen, G.H.3    van Veelen, C.W.4    van Rijen, P.C.5    Ramkema, M.6    Troost, D.7
  • 378
    • 0031791792 scopus 로고    scopus 로고
    • Glutamate receptors in epilepsy
    • Chapman, A. G. Glutamate receptors in epilepsy. Prog. Brain Res., 1998, 116, 371-383.
    • (1998) Prog. Brain Res. , vol.116 , pp. 371-383
    • Chapman, A.G.1
  • 379
    • 0038182258 scopus 로고    scopus 로고
    • Emerging signalling and protein interactions mediated via metabotropic glutamate receptors
    • Moldrich, R. X.; Beart, P. M. Emerging signalling and protein interactions mediated via metabotropic glutamate receptors. Curr. Drug Targets CNS Neurol. Disord., 2003, 2 (2), 109-122.
    • (2003) Curr. Drug Targets CNS Neurol. Disord. , vol.2 , Issue.2 , pp. 109-122
    • Moldrich, R.X.1    Beart, P.M.2
  • 380
    • 26844467224 scopus 로고    scopus 로고
    • Agonists and antagonists of metabotropic glutamate receptors: Anticonvulsants and antiepileptogenic agents?
    • Tang, F. R. Agonists and antagonists of metabotropic glutamate receptors: anticonvulsants and antiepileptogenic agents? Curr. Neuropharmacol., 2005, 3 (4), 299-307.
    • (2005) Curr. Neuropharmacol. , vol.3 , Issue.4 , pp. 299-307
    • Tang, F.R.1
  • 381
    • 0027432951 scopus 로고
    • Intracerebral 1S,3R-1-aminocyclopentane-1,3- dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists
    • Tizzano, J. P.; Griffey, K. I.; Johnson, J. A.; Fix, A. S.; Helton, D. R.; Schoepp, D. D. Intracerebral 1S,3R-1-aminocyclopentane-1,3- dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists. Neurosci. Lett., 1993, 162 (1-2), 12-16.
    • (1993) Neurosci. Lett. , vol.162 , Issue.1-2 , pp. 12-16
    • Tizzano, J.P.1    Griffey, K.I.2    Johnson, J.A.3    Fix, A.S.4    Helton, D.R.5    Schoepp, D.D.6
  • 382
    • 0028365897 scopus 로고
    • (S)-4- carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice
    • Thomsen, C.; Klitgaard, H.; Sheardown, M.; Jackson, H. C.; Eskesen, K.; Jacobsen, P.; Treppendahl, S.; Suzdak, P. D. (S)-4- carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice. J. Neurochem., 1994, 62 (6), 2492-2495.
    • (1994) J. Neurochem. , vol.62 , Issue.6 , pp. 2492-2495
    • Thomsen, C.1    Klitgaard, H.2    Sheardown, M.3    Jackson, H.C.4    Eskesen, K.5    Jacobsen, P.6    Treppendahl, S.7    Suzdak, P.D.8
  • 383
    • 0030088067 scopus 로고    scopus 로고
    • Modulation of seizure activity in mice by metabotropic glutamate receptor ligands
    • Dalby, N. O.; Thomsen, C. Modulation of seizure activity in mice by metabotropic glutamate receptor ligands. J. Pharmacol. Exp. Ther., 1996, 276 (2), 516-522.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , Issue.2 , pp. 516-522
    • Dalby, N.O.1    Thomsen, C.2
  • 384
    • 0033047613 scopus 로고    scopus 로고
    • Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)- 1-aminoindan-1,5-dicarboxylic acid)
    • Chapman, A. G.; Yip, P. K.; Yap, J. S.; Quinn, L. P.; Tang, E.; Harris, J. R.; Meldrum, B. S. Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)- 1-aminoindan-1,5-dicarboxylic acid). Eur. J. Pharmacol., 1999, 368 (1), 17-24.
    • (1999) Eur. J. Pharmacol. , vol.368 , Issue.1 , pp. 17-24
    • Chapman, A.G.1    Yip, P.K.2    Yap, J.S.3    Quinn, L.P.4    Tang, E.5    Harris, J.R.6    Meldrum, B.S.7
  • 385
    • 0030614535 scopus 로고    scopus 로고
    • Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse
    • Burgess, D. L.; Jones, J. M.; Meisler, M. H.; Noebels, J. L. Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell, 1997, 88 (3), 385-392.
    • (1997) Cell , vol.88 , Issue.3 , pp. 385-392
    • Burgess, D.L.1    Jones, J.M.2    Meisler, M.H.3    Noebels, J.L.4
  • 386
    • 4344707853 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptors interfere in different ways with pentylenetetrazole seizures, kindling, and kindling- related learning deficits
    • Nagaraja, R. Y.; Grecksch, G.; Reymann, K. G.; Schroeder, H.; Becker, A. Group I metabotropic glutamate receptors interfere in different ways with pentylenetetrazole seizures, kindling, and kindling- related learning deficits. Naunyn. Schmiedebergs. Arch. Pharmacol., 2004, 370 (1), 26-34.
    • (2004) Naunyn. Schmiedebergs. Arch. Pharmacol. , vol.370 , Issue.1 , pp. 26-34
    • Nagaraja, R.Y.1    Grecksch, G.2    Reymann, K.G.3    Schroeder, H.4    Becker, A.5
  • 387
    • 0032402917 scopus 로고    scopus 로고
    • Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice
    • Thomsen, C.; Dalby, N. O. Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice. Neuropharmacology, 1998, 37 (12), 1465-1473.
    • (1998) Neuropharmacology , vol.37 , Issue.12 , pp. 1465-1473
    • Thomsen, C.1    Dalby, N.O.2
  • 388
    • 1442274950 scopus 로고    scopus 로고
    • In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands
    • Smolders, I.; Lindekens, H.; Clinckers, R.; Meurs, A.; O'Neill, M. J.; Lodge, D.; Ebinger, G.; Michotte, Y. In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands. J. Neurochem., 2004, 88 (5), 1068-1077.
    • (2004) J. Neurochem. , vol.88 , Issue.5 , pp. 1068-1077
    • Smolders, I.1    Lindekens, H.2    Clinckers, R.3    Meurs, A.4    O'Neill, M.J.5    Lodge, D.6    Ebinger, G.7    Michotte, Y.8
  • 389
    • 0036852812 scopus 로고    scopus 로고
    • AIDA, a class I metabotropic glutamate-receptor antagonist limits kainate-induced hippocampal dysfunction
    • Renaud, J.; Emond, M.; Meilleur, S.; Psarropoulou, C.; Carmant, L. AIDA, a class I metabotropic glutamate-receptor antagonist limits kainate-induced hippocampal dysfunction. Epilepsia, 2002, 43 (11), 1306-1317.
    • (2002) Epilepsia , vol.43 , Issue.11 , pp. 1306-1317
    • Renaud, J.1    Emond, M.2    Meilleur, S.3    Psarropoulou, C.4    Carmant, L.5
  • 390
    • 0034105111 scopus 로고    scopus 로고
    • Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)- pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893)
    • Chapman, A. G.; Nanan, K.; Williams, M.; Meldrum, B. S. Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)- pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893). Neuropharmacology, 2000, 39 (9), 1567-1574.
    • (2000) Neuropharmacology , vol.39 , Issue.9 , pp. 1567-1574
    • Chapman, A.G.1    Nanan, K.2    Williams, M.3    Meldrum, B.S.4
  • 391
    • 48849109820 scopus 로고    scopus 로고
    • Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: A comparative real-time PCR analysis
    • Ermolinsky, B.; Pacheco Otalora, L. F.; Arshadmansab, M. F.; Zarei, M. M.; Garrido-Sanabria, E. R. Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: a comparative real-time PCR analysis. Brain Res., 2008, 1226, 173-180.
    • (2008) Brain Res , vol.1226 , pp. 173-180
    • Ermolinsky, B.1    Pacheco Otalora, L.F.2    Arshadmansab, M.F.3    Zarei, M.M.4    Garrido-Sanabria, E.R.5
  • 392
    • 54549089737 scopus 로고    scopus 로고
    • Impaired expression and function of group II metabotropic glutamate receptors in pilocarpine-treated chronically epileptic rats
    • Garrido-Sanabria, E. R.; Otalora, L. F.; Arshadmansab, M. F.; Herrera, B.; Francisco, S.; Ermolinsky, B. S. Impaired expression and function of group II metabotropic glutamate receptors in pilocarpine-treated chronically epileptic rats. Brain Res., 2008, 1240, 165-176.
    • (2008) Brain Res , vol.1240 , pp. 165-176
    • Garrido-Sanabria, E.R.1    Otalora, L.F.2    Arshadmansab, M.F.3    Herrera, B.4    Francisco, S.5    Ermolinsky, B.S.6
  • 393
    • 0032517175 scopus 로고    scopus 로고
    • Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R, 3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV)
    • Attwell, P. J.; Singh, K. N.; Jane, D. E.; Croucher, M. J.; Bradford, H. F. Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R, 3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV). Brain Res., 1998, 805 (1-2), 138-143.
    • (1998) Brain Res , vol.805 , Issue.1-2 , pp. 138-143
    • Attwell, P.J.1    Singh, K.N.2    Jane, D.E.3    Croucher, M.J.4    Bradford, H.F.5
  • 394
    • 0030926112 scopus 로고    scopus 로고
    • Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats
    • Tang, E.; Yip, P. K.; Chapman, A. G.; Jane, D. E.; Meldrum, B. S. Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats. Eur. J. Pharmacol., 1997, 327 (2-3), 109-115.
    • (1997) Eur. J. Pharmacol. , vol.327 , Issue.2-3 , pp. 109-115
    • Tang, E.1    Yip, P.K.2    Chapman, A.G.3    Jane, D.E.4    Meldrum, B.S.5
  • 395
    • 0031028197 scopus 로고    scopus 로고
    • Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat
    • Miyamoto, M.; Ishida, M.; Shinozaki, H. Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat. Neuroscience, 1997, 77 (1), 131-140.
    • (1997) Neuroscience , vol.77 , Issue.1 , pp. 131-140
    • Miyamoto, M.1    Ishida, M.2    Shinozaki, H.3
  • 396
    • 0034964561 scopus 로고    scopus 로고
    • Anti-epileptic activity of group II metabotropic glutamate receptor agonists (--)-2-oxa-4-aminobicyclo[3.1.0] hexane-4,6-dicarboxylate (LY379268) and (--)-2-thia-4-aminobicyclo [3.1.0]hexane-4,6-dicarboxylate (LY389795)
    • Moldrich, R. X.; Jeffrey, M.; Talebi, A.; Beart, P. M.; Chapman, A. G.; Meldrum, B. S. Anti-epileptic activity of group II metabotropic glutamate receptor agonists (--)-2-oxa-4-aminobicyclo[3.1.0] hexane-4,6-dicarboxylate (LY379268) and (--)-2-thia-4-aminobicyclo [3.1.0]hexane-4,6-dicarboxylate (LY389795). Neuropharmacology, 2001, 41 (1), 8-18.
    • (2001) Neuropharmacology , vol.41 , Issue.1 , pp. 8-18
    • Moldrich, R.X.1    Jeffrey, M.2    Talebi, A.3    Beart, P.M.4    Chapman, A.G.5    Meldrum, B.S.6
  • 397
    • 23244444497 scopus 로고    scopus 로고
    • Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8
    • Duvoisin, R. M.; Zhang, C.; Pfankuch, T. F.; O'Connor, H.; Gayet- Primo, J.; Quraishi, S.; Raber, J. Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8. Eur. J. Neurosci., 2005, 22 (2), 425-436.
    • (2005) Eur. J. Neurosci. , vol.22 , Issue.2 , pp. 425-436
    • Duvoisin, R.M.1    Zhang, C.2    Pfankuch, T.F.3    O'Connor, H.4    Gayet-Primo, J.5    Quraishi, S.6    Raber, J.7
  • 400
    • 13444304265 scopus 로고    scopus 로고
    • Expression analysis of metabotropic glutamate receptors I and III in mouse strains with different susceptibility to experimental temporal lobe epilepsy
    • Chen, J.; Larionov, S.; Pitsch, J.; Hoerold, N.; Ullmann, C.; Elger, C. E.; Schramm, J.; Becker, A. J. Expression analysis of metabotropic glutamate receptors I and III in mouse strains with different susceptibility to experimental temporal lobe epilepsy. Neurosci. Lett., 2005, 375 (3), 192-197.
    • (2005) Neurosci. Lett. , vol.375 , Issue.3 , pp. 192-197
    • Chen, J.1    Larionov, S.2    Pitsch, J.3    Hoerold, N.4    Ullmann, C.5    Elger, C.E.6    Schramm, J.7    Becker, A.J.8
  • 401
    • 0029768826 scopus 로고    scopus 로고
    • Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs
    • Ghauri, M.; Chapman, A. G.; Meldrum, B. S. Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs. Neuroreport., 1996, 7 (9), 1469-1474.
    • (1996) Neuroreport , vol.7 , Issue.9 , pp. 1469-1474
    • Ghauri, M.1    Chapman, A.G.2    Meldrum, B.S.3
  • 402
    • 0035919557 scopus 로고    scopus 로고
    • Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid
    • Chapman, A. G.; Talebi, A.; Yip, P. K.; Meldrum, B. S. Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid. Eur. J. Pharmacol., 2001, 424 (2), 107-113.
    • (2001) Eur. J. Pharmacol. , vol.424 , Issue.2 , pp. 107-113
    • Chapman, A.G.1    Talebi, A.2    Yip, P.K.3    Meldrum, B.S.4
  • 403
    • 0033592590 scopus 로고    scopus 로고
    • Anticonvulsant activity of a metabotropic glutamate receptor 8 preferential agonist, (R,S)-4-phosphonophenylglycine
    • Chapman, A. G.; Nanan, K.; Yip, P.; Meldrum, B. S. Anticonvulsant activity of a metabotropic glutamate receptor 8 preferential agonist, (R,S)-4-phosphonophenylglycine. Eur. J. Pharmacol., 1999, 383 (1), 23-27.
    • (1999) Eur. J. Pharmacol. , vol.383 , Issue.1 , pp. 23-27
    • Chapman, A.G.1    Nanan, K.2    Yip, P.3    Meldrum, B.S.4
  • 405
    • 38749146478 scopus 로고    scopus 로고
    • Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid
    • Folbergrova, J.; Druga, R.; Haugvicova, R.; Mares, P.; Otahal, J. Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid. Neuropharmacology, 2008, 54 (4), 665-675.
    • (2008) Neuropharmacology , vol.54 , Issue.4 , pp. 665-675
    • Folbergrova, J.1    Druga, R.2    Haugvicova, R.3    Mares, P.4    Otahal, J.5
  • 406
    • 0031000788 scopus 로고    scopus 로고
    • Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures
    • Hosford, D. A.; Wang, Y. Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures. Epilepsia, 1997, 38 (4), 408-414.
    • (1997) Epilepsia , vol.38 , Issue.4 , pp. 408-414
    • Hosford, D.A.1    Wang, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.