Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats

Pharmacology Biochemistry and Behavior

Volumn 73, Issue 2, 2002, Pages 419-427

  Simmons, Rosa Maria A ^a   Webster, Amy A ^a   Kalra, Anshu B ^a   Iyengar, Smriti ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

LY354740; LY379268; LY389795; mGlu2,3 receptors; Neuropathic pain; Persistent pain

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; 4 AMINO 2 THIABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; EGLUMETAD; LY 379267; METABOTROPIC RECEPTOR AGONIST; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; DIAGNOSTIC AGENT; FORMALDEHYDE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 2;

ALLODYNIA; ANIMAL MODEL; ARTICLE; ATAXIA; BEHAVIOR; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG SELECTIVITY; EVALUATION; IN VIVO STUDY; MALE; NERVE LIGATION; NEUROPATHY; NONHUMAN; PAIN; PERFORMANCE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SPINAL NERVE; STEREOCHEMISTRY; ANIMAL; BODY EQUILIBRIUM; CHEMICALLY INDUCED DISORDER; CHRONIC DISEASE; DRUG POTENTIATION; INTRAPERITONEAL DRUG ADMINISTRATION; LIGATION; PAIN ASSESSMENT; PERIPHERAL NEUROPATHY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; REACTION TIME; SPRAGUE DAWLEY RAT;

ANIMAL; ATAXIA; CHRONIC DISEASE; EQUILIBRIUM; EXCITATORY AMINO ACID AGONISTS; FORMALDEHYDE; INJECTIONS, INTRAPERITONEAL; LIGATION; MALE; PAIN; PAIN MEASUREMENT; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, METABOTROPIC GLUTAMATE; SPINAL NERVES; ANIMALS; MUSCULOSKELETAL EQUILIBRIUM;

ATAXIA;

EID: 0035996526     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(02)00849-3     Document Type: Article

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