The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus

Neuropharmacology

Volumn 36, Issue 11-12, 1997, Pages 1517-1532

  Palmer, M J ^a   Irving, A J ^b   Seabrook, G R ^c   Jane, D E ^a   Collingridge, G L ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

(2S,1'R,2'R,3'R) 2 (2',3' dicarboxycyclopropyl)glycine (DCG IV); (RS) 2 chloro 5 hydroxyphenylglycine (CHPG); (RS) 3,5 dihydroxyphenylglycine (DHPG); (S) 2 amino 4 phosphonobutanoic acid (L AP4); Glutamate; Hippocampal; Long term depression (LTD); Metabotropic glutamate (mGlu) receptor; N methyl D aspartate (NMDA) receptor; Synaptic plasticity

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 2 CHLORO 5 HYDROXYPHENYLGLYCINE; 3,5 DIHYDROXYPHENYLGLYCINE; EGLUMETAD; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PICROTOXIN; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HIPPOCAMPUS; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION;

ANIMALS; DEPRESSION, CHEMICAL; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID AGONISTS; FEMALE; GLYCINE; HIPPOCAMPUS; NEURONAL PLASTICITY; RATS; RECEPTORS, GABA-A; RESORCINOLS; SYNAPTIC TRANSMISSION;

EID: 0031406039     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00181-0     Document Type: Article

References (40)

1. Anderson W. W. and Collingridge G. L. (1997) A data acquisition program for on-line analysis of long-term potentiation and long-term depression. Society for Neuroscience Abstracts 264: 19.
2. Barrionuevo G., Schottler F. and Lynch G. (1980) The effects of repetitive low frequency stimulation on control and "potentiated" synaptic responses in the hippocampus. Life Sciences 27: 2385-2391.
3. Bashir Z. I., Jane D. E., Sunter D. C., Watkins J. C. and Collingridge G. L. (1993) Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus. European Journal of Pharmacology 239: 265-266.
4. Bashir Z. I. and Collingridge G. L. (1994) An investigation of depotentiation of long-term potentiation in the CA1 region of the hippocampus. Experimental Brain Research 100: 437-443.
5. Bear M. F. and Abraham W. C. (1996) Long-term depression in hippocampus. Annual Review of Neuroscience 19: 437-462.
6. Blake J. F., Brown M. W. and Collingridge G. L. (1988) CNQX blocks acidic amino acid induced depolarisations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices. Neuroscience 89: 182-186.
7. Bliss T. and Collingridge G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39.
8. Bolshakov V. Y. and Siegelbaum S. A. (1994) Postsynaptic induction and presynaptic expression of hippocampal longterm depression. Science 264: 1148-1152.
9. Bortolotto Z. A. and Collingridge G. L. (1993) Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus. Neuropharmacology 32: 1-9.
10. Bortolotto Z. A. and Collingridge G. L. (1995) On the mechanism of long-term potentiation induced by (1S,3R)-l-aminocyclopentane-l,3-dicarboxylic acid (ACPD) in rat hippocampal slices. Neuropharmacology 34: 1003-1014.
11. Coan E. J. and Collingridge G. L. (1985) Magnesium ions block an N-methyl-D-aspartate receptor-mediated component of synaptic transmission in rat hippocampus. Neuroscience Letters 53: 21-26.
12. Collins D. R. and Davies S. N. (1993) Co-administration of (1S,3R)-ACPD and arachidonic acid potentiates synaptic transmission in rat hippocampal slices. European Journal of Pharmacology 240: 325-326.
13. Davies C. H., Clarke V. R. J., Jane D. E. and Collingridge G. L. (1995) Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones. British Journal of Pharmacology 116: 1859-1869.
14. Doherty A. J., Palmer M. J., Henley J. M., Collingridge G. L. and Jane D. E. (1997) (RS)-2-Chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlul, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 36: 265-267.
15. Dudek S. M. and Bear M. F. (1992) Homosynaptic long-term depression in area CA1 of the hippocampus and the effects of NMDA receptor blockade. Proceedings of the National Academy of Sciences U.S.A. 89: 4363-4367.
16. Fitzjohn S. M., Irving A. J., Palmer M. J., Harvey J., Lodge D. and Collingridge G. L. (1996a) Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices. Neuroscience Letters 203: 211-213.
17. Fitzjohn, S. M., Lodge, D. and Collingridge, G. L. (1996b) Evidence for a presynaptic locus of expression of LTD induced by group I mGluRs in the CA1 region of the immature rat hippocampus. Society for Neuroscience Abstracts 686.3.
18. Fujii S., Saito K., Miyakawa H., Ito K. and Kalo H. (1991) Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CAI neurons of guinea pig hippocampal slices. Brain Research 555: 112-122.
19. Gereau R. W. and Conn P. J. (1995) Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CAI pyramidal cell excitability. Journal of Neurophysialogy 74: 122-129.
20. Harvey J. and Collingridge G. L. (1993) Signal transduction pathways involved in the acute potentiation of NMDA responses by 15,3R-ACPD in rat hippocampal slices. British Journal of Pharmacology 109: 1085-1090.
21. Harvey J., Palmer M. J., Irving A. J., Clarke V. R. J. and Collingridge G. L. (1996) NMDA receptor dependence of mGlu-mediated depression of synaptic transmission in the CAI region of the rat hippocampus. British Journal of Pharmacology 119: 1239-1247.
22. Herron C. E., Williamson R. and Collingridge G. L. (1985) A selective N-methyl-D-aspartate antagonist depresses epilepti-form activity in rat hippocampal slices. Neuroscience Letters 61: 255-260.
23. Irving A. J., Palmer M. J., Harvey J., Seabrook G. R. and Collingridge G. L. (1996) Long-term depression of synaptic transmission in the adult rat hippocampus by coactivation of NMDA and group I metabotropic glutamate receptors. Journal of Physiology (London) 495P: 49-50P.
24. Ishida M., Saitoh T., Shimamoto K., Ohfune Y. and Shinozaki H. (1993) A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord. British Journal of Pharmacology 109: 1169-1177.
25. Ito I., Kohda A., Tanabe S., Hirose E., Hayashi N., Mitsunaga S. and Sugiyama H. (1992) 3,5-Dihydroxyphenylglycine: a potent agonist of metabotropic glutamate receptors. Neuroreport 3: 1013-1016.
26. Kemp N. and Bashir Z. I. (1997) NMDA receptor-dependent and-independenl long-term depression in the CA1 region of the adult rat hippocampus in vitro. Neuropharmacology 36: 397-399.
27. Kerr D. S. and Abraham W. C. (1995) Cooperative interactions among afferents govern the induction of homosynaptic longterm depression in the hippocampus. Proceedings of the National Academy of Sciences U.S.A. 92: 11637-11641.
28. Manahan-Vaughan D. and Reymann K. G. (1995) 1S,3R-ACPD dose-dependently induces a slow-onset potentiation in the rat hippocampal CA1 region in vivo. Neuropharmacology 34: 1103-1105.
29. Mulkey R. M. and Malenka R. C. (1992) Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus. Neuron 9: 967-975.
30. Oliet S. H. R., Malenka R. C. and Nicoll R. A. (1997) Two distinct forms of long-term depression coexist in CA1 hippocampal pyramidal cells. Neuron 18: 969-982.
31. O'Mara S. M., Rowan M. J. and Anwyl R. (1995) Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro. Neuropharmacology 34: 983-989.
32. Ornstein P. L., Kingston A., Bleisch T. J., Arnold M. B., Wright R. A., Johnson B. G. and Schoepp D. D. (1997) Pharmacological characterization of LY341495, a potent antagonist of metabotropic glutamate receptors. Society for Neuroscience Abstracts 788: 10.
33. Overstreet L. S., Pasternak J. F., Colley P. A., Slater N. T. and Trommer B. L. (1997) Metabotropic glutamate receptor mediated long-term depression in developing hippocampus. Neuropharmacology 36: 831-844.
34. Pin J.-P. and Duvoisin R. (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34: 1-26.
35. Roberts P. J. (1995) Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenyglycine derivatives and other selective antagonists-an update. Neuropharmacology 34: 813-819.
36. Schoepp D. D., Goldsworthy J., Johnson B. G., Salhoff C. R. and Baker S. R. (1994) 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. Journal of Neurochemistry 63: 769-772.
37. Schoepp D. D., Johnson B. G., Wright R. A., Salhoff C. R., Mayne N. G., Wu S., Cockerham S. L., Paul Burnett L., Belegaje R., Bleakman D. and Monn J. A. (1997) LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors. Neuropharmacology 36: 1-11.
38. Selig D. K., Lee H. K., Bear M. F. and Malenka R. C. (1995) Re-examination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation. Journal of Neurophysiology 74: 1075-1082.
39. Staubli U. and Lynch G. (1990) Stable depression of potentiated synaptic responses in the hippocampus with 1-5 Hz stimulation. Brain Research 513: 113-118.
40. Wagner J. J. and Alger B. E. (1995) GABAergic and developmental influences on homosynaptic LTD and depotentiation in rat hippocampus. Journal of Neuroscience 15: 1577-1586.