Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A2A and dopamine D2 receptors

Neuroscience Letters

Volumn 324, Issue 2, 2002, Pages 154-158

  Díaz Cabiale, Zaida ^a   Vivó, Meritxell ^a,b   Del Arco, Alberto ^a   O'Connor, William T ^c   Harte, Michael K ^c   Müller, Christa E ^d   Martínez, Emili ^b   Popoli, Patrizia ^e   Fuxe, Kjell ^a   Ferré, Sergi ^a,f  

^a KAROLINSKA INSTITUTE   (Sweden)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF BONN   (Germany)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^f NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Adenosine A2A receptor; Dopamine D2 receptor; Gamma aminobutyric acid; Metabotropic mGlu5 receptor; Microdialysis; Nucleus accumbens; Phencyclidine; Ventral pallidum

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLORO 5 HYDROXYPHENYLGLYCINE; 4 AMINOBUTYRIC ACID RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; GLUTAMATE RECEPTOR AGONIST; METABOTROPIC RECEPTOR; QUINPIROLE;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DEPENDENCE; GLOBUS PALLIDUS; MALE; MICRODIALYSIS; NEUROMODULATION; NONHUMAN; NUCLEUS ACCUMBENS; PERFUSION; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; SCHIZOPHRENIA; SIGNAL TRANSDUCTION;

ADENOSINE; ANIMALS; ANTIHYPERTENSIVE AGENTS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; EXTRACELLULAR SPACE; GAMMA-AMINOBUTYRIC ACID; GLOBUS PALLIDUS; GLUTAMIC ACID; MALE; MICRODIALYSIS; NEURAL INHIBITION; NEURAL PATHWAYS; NEURONS; NUCLEUS ACCUMBENS; PHENETHYLAMINES; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A2A; RECEPTORS, DOPAMINE D2; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, PURINERGIC P1; SYNAPTIC TRANSMISSION; XANTHINES;

EID: 0037123728     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00179-9     Document Type: Article

References (20)

1. Interactions between glutamatergic and monoaminergic systems within the basal ganglia - Implications for schizophrenia and Parkinson's disease
2. Adenosine-dopamine interactions in the ventral striatum. Implications for the treatment of schizophrenia
3. Clozapine decreases serotonin extracellular levels in the nucleus accumbens by a dopamine receptor-independent mechanism
4. 2 receptors in the ventral striopallidal system. Implications for the treatment of schizophrenia
5. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
6. Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum
7. 2 dopamine receptors in rat striatum
8. 14C]-2-deoxyglucose autoradiographic study
9. The role of the striatopallidal and extended amygdala systems in drug addiction
10. Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors
11. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
12. Systemic administration of adenosine A(2A) receptor antagonist reverses increased GABA release in the globus pallidus of unilateral 6-hydroxydopamine-lesioned rats: A microdialysis study
13. The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: Possible involvement of A2A receptors
14. The selective mGlu5 receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D2 receptors in the rat striatum
15. Multiple intramembrane receptor-receptor interactions in the regulation of striatal dopamine D2 receptors
16. Water soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A2A-selective adenosine receptor antagonists
17. 2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: An in situ hybridization histochemistry study
18. Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
19. Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas
20. Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons