The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: A comparison

Psychopharmacology

Volumn 179, Issue 1, 2005, Pages 218-229

  Ballard, Theresa M ^a   Woolley, Marie L ^a,b   Prinssen, Eric ^a   Huwyler, Jörg ^a   Porter, Richard ^a   Spooren, Will ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Anxiety; Cognition; Conditioned emotional response; Conflict task; Delayed match to position; mGlu5 receptor antagonist; MPEP; Rat; Water maze

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; BENZODIAZEPINE; DIAZEPAM; METABOTROPIC RECEPTOR 5 ANTAGONIST; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; BRAIN; COGNITION; CONDITIONING; CONFLICT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; DRUG SELECTIVITY; EMOTION; MALE; MAZE TEST; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; RODENT; SPATIAL MEMORY; TASK PERFORMANCE; TRANQUILIZING ACTIVITY;

ANIMALS; ANXIETY; BRAIN; CHOICE BEHAVIOR; COGNITION; CONDITIONING (PSYCHOLOGY); CONFLICT (PSYCHOLOGY); DIAZEPAM; EXCITATORY AMINO ACID ANTAGONISTS; FEAR; MALE; MAZE LEARNING; PYRIDINES; RATS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 17744373871     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-005-2211-9     Document Type: Article

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