메뉴 건너뛰기




Volumn 77, Issue 1, 1997, Pages 131-140

Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat

Author keywords

Intraventricular injection; Kainic acid; Limbic motor seizures; Neuron damage

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; ANTICONVULSIVE AGENT; EXCITOTOXIN; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; KAINIC ACID; METABOTROPIC RECEPTOR; NEUROPROTECTIVE AGENT;

EID: 0031028197     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00442-3     Document Type: Article
Times cited : (69)

References (52)
  • 1
    • 0027135273 scopus 로고
    • A paradox after systemic kainate injection in rats: Lesser damage of hippocampal CA1 neurons after higher doses
    • Balchen T., Berg M., Diemer N. H. A paradox after systemic kainate injection in rats: lesser damage of hippocampal CA1 neurons after higher doses. Neurosci. Lett. 163:1993;151-154.
    • (1993) Neurosci. Lett. , vol.163 , pp. 151-154
    • Balchen, T.1    Berg, M.2    Diemer, N.H.3
  • 2
    • 0029121515 scopus 로고
    • Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration
    • Bruno V., Battaglia G., Copani A., Giffard R. G., Raciti G., Raffaele R., Shinozaki H., Nicoletti F. Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. Eur. J. Neurosci. 7:1995;1906-1913.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1906-1913
    • Bruno, V.1    Battaglia, G.2    Copani, A.3    Giffard, R.G.4    Raciti, G.5    Raffaele, R.6    Shinozaki, H.7    Nicoletti, F.8
  • 3
    • 0028351384 scopus 로고
    • Protective effect of the metabotropic glutamate receptor agonist DCG-IV, against excitotoxic neuronal death
    • Bruno V., Copani A., Battaglia G., Raffaele R., Shinozaki H., Nicoletti F. Protective effect of the metabotropic glutamate receptor agonist DCG-IV, against excitotoxic neuronal death. Eur. J. Pharmac. 256:1994;109-112.
    • (1994) Eur. J. Pharmac. , vol.256 , pp. 109-112
    • Bruno, V.1    Copani, A.2    Battaglia, G.3    Raffaele, R.4    Shinozaki, H.5    Nicoletti, F.6
  • 4
    • 0028852627 scopus 로고
    • Modulation of epileptiform activity by metabotropic glutamate receptors in immature rat neocortex
    • Burke J. P., Hablitz J. J. Modulation of epileptiform activity by metabotropic glutamate receptors in immature rat neocortex. J. Neurophysiol. 73:1995;205-217.
    • (1995) J. Neurophysiol. , vol.73 , pp. 205-217
    • Burke, J.P.1    Hablitz, J.J.2
  • 5
    • 0021277649 scopus 로고
    • Changes in regional neurotransmitter amino acid levels in rat brain during seizures induced by L-allyglycine, bicuculline, and kainic acid
    • Chapman A. G., Westerberg E., Premachandra M., Meldrum B. S. Changes in regional neurotransmitter amino acid levels in rat brain during seizures induced by L-allyglycine, bicuculline, and kainic acid. J. Neurochem. 43:1984;62-70.
    • (1984) J. Neurochem. , vol.43 , pp. 62-70
    • Chapman, A.G.1    Westerberg, E.2    Premachandra, M.3    Meldrum, B.S.4
  • 6
    • 0028036657 scopus 로고
    • The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells
    • Chavis P., Shinozaki H., Bockaert J., Fagni L. The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells. J. Neurosci. 14:1994;7067-7076.
    • (1994) J. Neurosci. , vol.14 , pp. 7067-7076
    • Chavis, P.1    Shinozaki, H.2    Bockaert, J.3    Fagni, L.4
  • 7
    • 0026647040 scopus 로고
    • Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia
    • Chiamulera C., Albertini P., Valerio E., Reggiani A. Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia. Eur. J. Pharmac. 216:1992;335-336.
    • (1992) Eur. J. Pharmac. , vol.216 , pp. 335-336
    • Chiamulera, C.1    Albertini, P.2    Valerio, E.3    Reggiani, A.4
  • 8
    • 0030071636 scopus 로고    scopus 로고
    • 2+ channels involves multiple receptor subtypes in cortical neurons
    • 2+ channels involves multiple receptor subtypes in cortical neurons. J. Neurosci. 16:1996;36-45.
    • (1996) J. Neurosci. , vol.16 , pp. 36-45
    • Choi, S.1    Lovinger, D.M.2
  • 9
    • 0019954365 scopus 로고
    • Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors
    • Ferkany J. W., Zaczek R., Coyle J. T. Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors. Nature. 298:1982;757-759.
    • (1982) Nature , vol.298 , pp. 757-759
    • Ferkany, J.W.1    Zaczek, R.2    Coyle, J.T.3
  • 11
    • 0028851850 scopus 로고
    • Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1
    • Gereau IV R. W., Conn P. J. Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1. J. Neurosci. 15:1995;6879-6889.
    • (1995) J. Neurosci. , vol.15 , pp. 6879-6889
    • Gereau R.W. IV1    Conn, P.J.2
  • 13
    • 0026756866 scopus 로고
    • Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells
    • Hayashi Y., Tanabe Y., Aramori I., Masu M., Shimamoto K., Ohfune Y., Nakanishi S. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br. J. Pharmac. 107:1992;539-543.
    • (1992) Br. J. Pharmac. , vol.107 , pp. 539-543
    • Hayashi, Y.1    Tanabe, Y.2    Aramori, I.3    Masu, M.4    Shimamoto, K.5    Ohfune, Y.6    Nakanishi, S.7
  • 14
    • 0025696335 scopus 로고
    • A potent metabotropic glutamate receptor agonist: Electrophysiological actions of a conformationally restricted glutamate analogue in the rat spinal cord and Xenopus oocytes
    • Ishida M., Akagi H., Shimamoto K., Ohfune Y., Shinozaki H. A potent metabotropic glutamate receptor agonist: electrophysiological actions of a conformationally restricted glutamate analogue in the rat spinal cord and Xenopus oocytes. Brain Res. 537:1990;311-314.
    • (1990) Brain Res. , vol.537 , pp. 311-314
    • Ishida, M.1    Akagi, H.2    Shimamoto, K.3    Ohfune, Y.4    Shinozaki, H.5
  • 15
    • 0027209890 scopus 로고
    • A novel metabotropic glutamate receptor agonist: Marked depression of monosynaptic excitation in the isolated newborn rat spinal cord
    • Ishida M., Saitoh T., Shimamoto K., Ohfune Y., Shinozaki H. A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the isolated newborn rat spinal cord. Br. J. Pharmac. 109:1993;1169-1177.
    • (1993) Br. J. Pharmac. , vol.109 , pp. 1169-1177
    • Ishida, M.1    Saitoh, T.2    Shimamoto, K.3    Ohfune, Y.4    Shinozaki, H.5
  • 16
    • 0027435172 scopus 로고
    • A new metabotropic glutamate receptor agonist: Developmental change of its sensitivity to receptors in the newborn rat spinal cord
    • Ishida M., Saitoh T., Shinozaki H. A new metabotropic glutamate receptor agonist: developmental change of its sensitivity to receptors in the newborn rat spinal cord. Neurosci. Lett. 160:1993;156-158.
    • (1993) Neurosci. Lett. , vol.160 , pp. 156-158
    • Ishida, M.1    Saitoh, T.2    Shinozaki, H.3
  • 17
    • 0029102084 scopus 로고
    • Novel agonists for metabotropic glutamate receptors: Trans- And cis-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (trans- And cis-MCG-I)
    • Ishida M., Saitoh T., Shinozaki H. Novel agonists for metabotropic glutamate receptors: trans- and cis-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (trans- and cis-MCG-I). Neuropharmacology. 34:1995;821-827.
    • (1995) Neuropharmacology , vol.34 , pp. 821-827
    • Ishida, M.1    Saitoh, T.2    Shinozaki, H.3
  • 19
    • 0029995540 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fiber synapse
    • Kamiya H., Shinozaki H., Yamamoto C. Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fiber synapse. J. Physiol. 493:1996;447-455.
    • (1996) J. Physiol. , vol.493 , pp. 447-455
    • Kamiya, H.1    Shinozaki, H.2    Yamamoto, C.3
  • 20
    • 0026093753 scopus 로고
    • Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures
    • Koh J. Y., Palmer E., Cotman A. W. Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures. Proc. natn. Acad. Sci. U.S.A. 88:1991;9431-9435.
    • (1991) Proc. Natn. Acad. Sci. U.S.A. , vol.88 , pp. 9431-9435
    • Koh, J.Y.1    Palmer, E.2    Cotman, A.W.3
  • 21
    • 0018713586 scopus 로고
    • Hippocampal lesions indicate differences between excitotoxic properties of acidic amino acids
    • Köhler C., Schwarcz R., Fuxe K. Hippocampal lesions indicate differences between excitotoxic properties of acidic amino acids. Neurosci. Lett. 175:1978;366-371.
    • (1978) Neurosci. Lett. , vol.175 , pp. 366-371
    • Köhler, C.1    Schwarcz, R.2    Fuxe, K.3
  • 22
    • 4243557572 scopus 로고
    • A potent metabotropic glutamate receptor agonist preferentially inhibits excitatory synaptic inputs to substantia nigral neurons in rat midbrain slices
    • Konishi S., Ishida M., Shinozaki H. A potent metabotropic glutamate receptor agonist preferentially inhibits excitatory synaptic inputs to substantia nigral neurons in rat midbrain slices. Jpn. J. Pharmac. 64:1994;O-362.
    • (1994) Jpn. J. Pharmac. , vol.64 , pp. 362
    • Konishi, S.1    Ishida, M.2    Shinozaki, H.3
  • 23
    • 0011729661 scopus 로고
    • Selective presynaptic depression by a metabotropic glutamate receptor agonist of GABA-mediated inhibitory transmission in rat cerebellar Purkinje cells
    • Konishi S., Mitoma H., Ishida M., Shinozaki H. Selective presynaptic depression by a metabotropic glutamate receptor agonist of GABA-mediated inhibitory transmission in rat cerebellar Purkinje cells. Jpn. J. Pharmac. 67:1995;S4-6.
    • (1995) Jpn. J. Pharmac. , vol.67 , pp. 4-6
    • Konishi, S.1    Mitoma, H.2    Ishida, M.3    Shinozaki, H.4
  • 24
    • 0030218993 scopus 로고    scopus 로고
    • Neurotoxicity of DCG-IV, a potent agonist for metabotropic glutamate receptors, in the rat
    • Kwak S., Miyamoto M., Ishida M., Shinozaki H. Neurotoxicity of DCG-IV, a potent agonist for metabotropic glutamate receptors, in the rat. Neuroscience. 73:1996;687-695.
    • (1996) Neuroscience , vol.73 , pp. 687-695
    • Kwak, S.1    Miyamoto, M.2    Ishida, M.3    Shinozaki, H.4
  • 25
    • 0022383917 scopus 로고
    • Effects of status epilepticus on extracellular amino acids in the hippocampus
    • Lehmann A., Hagberg H., Jacobson I., Hamberger A. Effects of status epilepticus on extracellular amino acids in the hippocampus. Brain Res. 359:1985;147-151.
    • (1985) Brain Res. , vol.359 , pp. 147-151
    • Lehmann, A.1    Hagberg, H.2    Jacobson, I.3    Hamberger, A.4
  • 26
    • 0010466533 scopus 로고
    • In rats, the metabotropic glutamate receptor-triggered hippocampal neuronal damage is strain-dependent
    • Lipartiti M., Fadda E., Savoini G., Siliprandi R., Sautter J., Arban R., Manev H. In rats, the metabotropic glutamate receptor-triggered hippocampal neuronal damage is strain-dependent. Life Sci. 52:1993;85-90.
    • (1993) Life Sci. , vol.52 , pp. 85-90
    • Lipartiti, M.1    Fadda, E.2    Savoini, G.3    Siliprandi, R.4    Sautter, J.5    Arban, R.6    Manev, H.7
  • 27
    • 0027440927 scopus 로고
    • Effect of temperature on kainic acid-induced seizures
    • Liu Z., Gatt A., Mikati M., Holmes G. L. Effect of temperature on kainic acid-induced seizures. Brain Res. 631:1993;51-58.
    • (1993) Brain Res. , vol.631 , pp. 51-58
    • Liu, Z.1    Gatt, A.2    Mikati, M.3    Holmes, G.L.4
  • 28
    • 0019501929 scopus 로고
    • Kainic acid induced limbic seizures: Metabolic, behavioral, electroencephalographic and neuropathological correlates
    • Lothman E. W., Collins R. C. Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates. Brain Res. 218:1981;299-318.
    • (1981) Brain Res. , vol.218 , pp. 299-318
    • Lothman, E.W.1    Collins, R.C.2
  • 29
    • 0027138725 scopus 로고
    • Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist
    • McDonald J. W., Fix A. S., Tizzano J. P., Schoepp D. D. Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist. J. Neurosci. 13:1993;4445-4455.
    • (1993) J. Neurosci. , vol.13 , pp. 4445-4455
    • McDonald, J.W.1    Fix, A.S.2    Tizzano, J.P.3    Schoepp, D.D.4
  • 30
    • 0017913106 scopus 로고
    • Kainate-induced degeneration of neostriatal neurons: Dependency upon corticostrial tract
    • McGeer E. G., McGeer P. L., Singh K. Kainate-induced degeneration of neostriatal neurons: dependency upon corticostrial tract. Brain Res. 139:1978;381-383.
    • (1978) Brain Res. , vol.139 , pp. 381-383
    • McGeer, E.G.1    McGeer, P.L.2    Singh, K.3
  • 31
    • 0011737235 scopus 로고
    • Metabotropic glutamate receptor activation selectively suppresses GABA-mediated inhibition in rat cerebellar Purkinje cells
    • Mitoma H., Kobayashi T., Ishida M., Shinozaki H., Konishi S. Metabotropic glutamate receptor activation selectively suppresses GABA-mediated inhibition in rat cerebellar Purkinje cells. Neurosci. Res. Suppl. 19:1994;217.
    • (1994) Neurosci. Res. , vol.19 , pp. 217
    • Mitoma, H.1    Kobayashi, T.2    Ishida, M.3    Shinozaki, H.4    Konishi, S.5
  • 32
    • 0028362116 scopus 로고
    • Agonist for metabotropic glutamate receptors in the rat delay recovery from halothane anesthesia
    • Miyamoto M., Ishida M., Kwak S., Shinozaki H. Agonist for metabotropic glutamate receptors in the rat delay recovery from halothane anesthesia. Eur. J. Pharmac. 260:1994;99-102.
    • (1994) Eur. J. Pharmac. , vol.260 , pp. 99-102
    • Miyamoto, M.1    Ishida, M.2    Kwak, S.3    Shinozaki, H.4
  • 33
    • 0017844923 scopus 로고
    • Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
    • Nadler J. V., Perry B. W., Cotman C. W. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature. 271:1978;676-677.
    • (1978) Nature , vol.271 , pp. 676-677
    • Nadler, J.V.1    Perry, B.W.2    Cotman, C.W.3
  • 34
    • 0025079146 scopus 로고
    • (2S,3S,4S)-α-(Carboxycycloproply)glycine is a novel agonist of metabotropic glutamate receptors
    • Nakagawa Y., Saitoh K., Isihara T., Ishida M., Shinozaki H. (2S,3S,4S)-α-(Carboxycycloproply)glycine is a novel agonist of metabotropic glutamate receptors. Eur. J. Pharmac. 184:1990;205-206.
    • (1990) Eur. J. Pharmac. , vol.184 , pp. 205-206
    • Nakagawa, Y.1    Saitoh, K.2    Isihara, T.3    Ishida, M.4    Shinozaki, H.5
  • 35
    • 0026437728 scopus 로고
    • Molecular diversity of glutamate receptors and implications for brain function
    • Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science. 258:1992;597-603.
    • (1992) Science , vol.258 , pp. 597-603
    • Nakanishi, S.1
  • 36
    • 0027190384 scopus 로고
    • Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat
    • Ohishi H., Sigemoto R., Nakanishi S., Mizuno N. Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat. Neuroscience. 53:1993;1009-1018.
    • (1993) Neuroscience , vol.53 , pp. 1009-1018
    • Ohishi, H.1    Sigemoto, R.2    Nakanishi, S.3    Mizuno, N.4
  • 38
    • 0028912822 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin J.-P., Duvoisin R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology. 34:1995;1-26.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.-P.1    Duvoisin, R.2
  • 39
    • 0027216836 scopus 로고
    • Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells
    • Pizzi M., Fallacara C., Arrighi V., Memo M., Spano P. F. Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells. J. Neurochem. 61:1993;683-689.
    • (1993) J. Neurochem. , vol.61 , pp. 683-689
    • Pizzi, M.1    Fallacara, C.2    Arrighi, V.3    Memo, M.4    Spano, P.F.5
  • 40
    • 0029003570 scopus 로고
    • Dual modulation of synaptic inhibition by distinct metabotropic glutamate receptors in the rat hippocampus
    • Poncer J. C., Shinozaki H., Miles R. Dual modulation of synaptic inhibition by distinct metabotropic glutamate receptors in the rat hippocampus. J. Physiol. 485:1995;121-134.
    • (1995) J. Physiol. , vol.485 , pp. 121-134
    • Poncer, J.C.1    Shinozaki, H.2    Miles, R.3
  • 41
    • 0029151828 scopus 로고
    • Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): Phenylglycine derivatives and other selective antagonists - An update
    • Roberts P. J. Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenylglycine derivatives and other selective antagonists - An update. Neuropharmacology. 34:1995;813-820.
    • (1995) Neuropharmacology , vol.34 , pp. 813-820
    • Roberts, P.J.1
  • 42
    • 0026513647 scopus 로고
    • Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage
    • Sacaan A. I., Schoepp D. D. Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage. Neurosci. Lett. 139:1992;77-82.
    • (1992) Neurosci. Lett. , vol.139 , pp. 77-82
    • Sacaan, A.I.1    Schoepp, D.D.2
  • 43
    • 0027395275 scopus 로고
    • Metabotropic glutamate receptors in brain function and pathology
    • Schoepp D. D., Conn P. J. Metabotropic glutamate receptors in brain function and pathology. Trends pharmac. Sci. 14:1993;13-20.
    • (1993) Trends Pharmac. Sci. , vol.14 , pp. 13-20
    • Schoepp, D.D.1    Conn, P.J.2
  • 44
    • 0027934857 scopus 로고
    • 3,5-Dihydroxyphenylglycine is highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus
    • Schoepp D. D., Goldsworthy J., Johnson B. G., Salhoff C. R., Baker S. R. 3,5-Dihydroxyphenylglycine is highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. J. Neurochem. 63:1994;769-772.
    • (1994) J. Neurochem. , vol.63 , pp. 769-772
    • Schoepp, D.D.1    Goldsworthy, J.2    Johnson, B.G.3    Salhoff, C.R.4    Baker, S.R.5
  • 45
    • 0028128947 scopus 로고
    • Neuron damage induced by some potent kainoids and neuroprotective action of new agonists for metabotropic glutamate receptors
    • Shinozaki H. Neuron damage induced by some potent kainoids and neuroprotective action of new agonists for metabotropic glutamate receptors. Eur. Neurol. 34 ((Suppl. 3)):1994;2-9.
    • (1994) Eur. Neurol. , vol.34 , Issue.3 , pp. 2-9
    • Shinozaki, H.1
  • 46
    • 0028057773 scopus 로고
    • Kainic acid seizures in the rat
    • Sperk G. Kainic acid seizures in the rat. Prog. Neurobiol. 42:1994;1-42.
    • (1994) Prog. Neurobiol. , vol.42 , pp. 1-42
    • Sperk, G.1
  • 47
    • 0027410488 scopus 로고
    • Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4
    • Tanabe Y., Nomura A., Masu M., Shigemoto R., Mizuno N., Nakanishi S. Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4. J. Neurosci. 13:1993;1372-1378.
    • (1993) J. Neurosci. , vol.13 , pp. 1372-1378
    • Tanabe, Y.1    Nomura, A.2    Masu, M.3    Shigemoto, R.4    Mizuno, N.5    Nakanishi, S.6
  • 48
    • 0028365897 scopus 로고
    • (S)-4-Carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR)1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice
    • Thomsen C., Klitgaard H., Sheardown M., Jackson H. C., Eskesen K., Jacobsen P., Treppendahl S., Suzdak P. D. (S)-4-Carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR)1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice. J. Neurochem. 62:1994;2492-2495.
    • (1994) J. Neurochem. , vol.62 , pp. 2492-2495
    • Thomsen, C.1    Klitgaard, H.2    Sheardown, M.3    Jackson, H.C.4    Eskesen, K.5    Jacobsen, P.6    Treppendahl, S.7    Suzdak, P.D.8
  • 49
    • 0027432951 scopus 로고
    • Intracerebral 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists
    • Tizzano J. P., Griffey K. I., Johnson J. A., Fix A. S., Helton D. R., Schoepp D. D. Intracerebral 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists. Neurosci. Lett. 162:1993;12-16.
    • (1993) Neurosci. Lett. , vol.162 , pp. 12-16
    • Tizzano, J.P.1    Griffey, K.I.2    Johnson, J.A.3    Fix, A.S.4    Helton, D.R.5    Schoepp, D.D.6
  • 50
    • 0029097032 scopus 로고
    • Induction or protection of limbic seizures in mice by mGluR subtype selective agonists
    • Tizzano J. P., Griffey K. I., Schoepp D. D. Induction or protection of limbic seizures in mice by mGluR subtype selective agonists. Neuropharmacology. 34:1995;1063-1067.
    • (1995) Neuropharmacology , vol.34 , pp. 1063-1067
    • Tizzano, J.P.1    Griffey, K.I.2    Schoepp, D.D.3
  • 51
    • 0027992583 scopus 로고
    • Phenylglycine derivatives as antagonists of metabotropic glutamate receptors
    • Watkins J., Collingridge G. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends pharmac. Sci. 15:1994;333-342.
    • (1994) Trends Pharmac. Sci. , vol.15 , pp. 333-342
    • Watkins, J.1    Collingridge, G.2
  • 52
    • 0028025658 scopus 로고
    • Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons
    • Wilsch V. W., Pidoplichko V. I., Opitz T., Shinozaki H., Reymann K. G. Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons. Eur. J. Pharmac. 262:1994;287-291.
    • (1994) Eur. J. Pharmac. , vol.262 , pp. 287-291
    • Wilsch, V.W.1    Pidoplichko, V.I.2    Opitz, T.3    Shinozaki, H.4    Reymann, K.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.