Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: A comparative real-time PCR analysis

Brain Research

Volumn 1226, Issue , 2008, Pages 173-180

  Ermolinsky, Boris ^a,b   Pacheco Otalora, Luis F ^a   Arshadmansab, Massoud F ^a   Zarei, Masoud M ^a,b   Garrido Sanabria, Emilio R ^a,b  

^a UNIVERSITY OF TEXAS AT BROWNSVILLE   (United States)

^b The Center for Biomedical Studies   (United States)

Author keywords

Epilepsy; Granule cell; Metabotropic glutamate receptor; Pilocarpine; Presynaptic

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DENTATE GYRUS; EPILEPTIC STATE; EPILEPTOGENESIS; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION;

ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; PILOCARPINE; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER; STATUS EPILEPTICUS; TIME FACTORS;

RATTUS;

EID: 48849109820     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.05.073     Document Type: Article

References (45)

1. Aronica E., van Vliet E.A., Mayboroda O.A., Troost D., da Silva F.H., and Gorter J.A. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur J Neurosci. 12 (2000) 2333-2344
2. Aronica E., van Vliet E.A., Mayboroda O.A., Troost D., da Silva F.H., and Gorter J.A. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur J Neurosci. 12 (2000) 2333-2344
3. Aronica E., and Gorter J.A. Gene expression profile in temporal lobe epilepsy. Neuroscientist 13 (2007) 100-108
4. Aronica E.M., Gorter J.A., Paupard M.C., Grooms S.Y., Bennett M.V., and Zukin R.S. Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats. J Neurosci. 17 (1997) 8588-8595
5. Aronica E.M., Gorter J.A., Paupard M.C., Grooms S.Y., Bennett M.V., and Zukin R.S. Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats. J Neurosci. 17 (1997) 8588-8595
6. Bruno V., Sureda F.X., Storto M., Casabona G., Caruso A., Knopfel T., Kuhn R., and Nicoletti F. The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling. J Neurosci. 17 (1997) 1891-1897
7. Cavalheiro E.A. The pilocarpine model of epilepsy. Ital J Neurol Sci. 16 (1995) 33-37
8. Danzer S.C., and McNamara J.O. Localization of brain-derived neurotrophic factor to distinct terminals of mossy fiber axons implies regulation of both excitation and feedforward inhibition of CA3 pyramidal cells. J Neurosci. 24 (2004) 11346-11355
9. Elliott R.C., and Lowenstein D.H. Gene expression profiling of seizure disorders. Neurochem Res. 29 (2004) 1083-1092
10. Fink K., Dooley D.J., Meder W.P., Suman-Chauhan N., Duffy S., Clusmann H., and Gothert M. Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex. Neuropharmacology 42 (2002) 229-236
11. Gorter J.A., van Vliet E.A., Aronica E., Breit T., Rauwerda H., Lopes da Silva F.H., and Wadman W.J. Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J Neurosci. 26 (2006) 11083-11110
12. Hatazaki S., Bellver-Estelles C., Jimenez-Mateos E.M., Meller R., Bonner C., Murphy N., Matsushima S., Taki W., Prehn J.H., Simon R.P., and Henshall D.C. Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning. Neuroscience 150 (2007) 467-477
13. Hunsberger J.G., Bennett A.H., Selvanayagam E., Duman R.S., and Newton S.S. Gene profiling the response to kainic acid induced seizures. Brain Res Mol Brain Res. 141 (2005) 95-112
14. Kamiya H., Shinozaki H., and Yamamoto C. Activation of metabotropic glutamate receptor type 2/3 suppresses transmission at rat hippocampal mossy fibre synapses. J Physiol. 493 Pt 2 (1996) 447-455
15. Kew J.N., Ducarre J.M., Pflimlin M.C., Mutel V., and Kemp J.A. Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1. Neuropharmacology 40 (2001) 20-27
16. Kilbride J., Rush A.M., Rowan M.J., and Anwyl R. Presynaptic group II mGluR inhibition of short-term depression in the medial perforant path of the dentate gyrus in vitro. J Neurophysiol. 85 (2001) 2509-2515
17. Kwan P., and Brodie M.J. Refractory epilepsy: mechanisms and solutions. Expert Rev Neurother. 6 (2006) 397-406
18. Lea P.M.t., Wroblewska B., Sarvey J.M., and Neale J.H. beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. J Neurophysiol. 85 (2001) 1097-1106
19. Lee T.S., Mane S., Eid T., Zhao H., Lin A., Guan Z., Kim J.H., Schweitzer J., King-Stevens D., Weber P., Spencer S.S., Spencer D.D., and de Lanerolle N.C. Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol Med. 13 (2007) 1-13
20. Lemos T., and Cavalheiro E.A. Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats. Exp Brain Res. 102 (1995) 423-428
21. Lemos T., and Cavalheiro E.A. Status epilepticus and the late development of spontaneous seizures in the pilocarpine model of epilepsy. Epilepsy Res Suppl. 12 (1996) 137-144
22. Liu Z., Mikati M., and Holmes G.L. Mesial temporal sclerosis: pathogenesis and significance. Pediatr Neurol. 12 (1995) 5-16
23. Lukasiuk K., Kontula L., and Pitkanen A. cDNA profiling of epileptogenesis in the rat brain. Eur J Neurosci. 17 (2003) 271-279
24. Macdonald R.L. Is there a mechanistic basis for rational polypharmacy?. Epilepsy Res Suppl. 11 (1996) 79-93
25. Majores M., Schoch S., Lie A., and Becker A.J. Molecular neuropathology of temporal lobe epilepsy: complementary approaches in animal models and human disease tissue. Epilepsia 48 Suppl 2 (2007) 4-12
26. Manzoni O.J., Castillo P.E., and Nicoll R.A. Pharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus. Neuropharmacology 34 (1995) 965-971
27. Mello L.E., Cavalheiro E.A., Tan A.M., Kupfer W.R., Pretorius J.K., Babb T.L., and Finch D.M. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting. Epilepsia 34 (1993) 985-995
28. Omori K., Inagaki C., and Sasa M. [Molecular mechanism underlying epileptic seizure: forwards development of novel drugs for untreatable epilepsy]. Nippon Yakurigaku Zasshi 114 (1999) 161-168
29. Pacheco Otalora L.F., Couoh J., Shigamoto R., Zarei M.M., and Garrido Sanabria E.R. Abnormal mGlu2/3 expression in the perforant path termination zones and mossy fibers of chronically epileptic rats. Brain Res. 1098 (2006) 170-185
30. Pacheco Otalora L.F., Hernandez E.F., Arshadmansab M.F., Francisco S., Willis M., Ermolinsky B., Zarei M., Knaus H.G., and Garrido-Sanabria E.R. Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy. Brain Res (2008)
31. Petralia R.S., Wang Y.X., Niedzielski A.S., and Wenthold R.J. The metabotropic glutamate receptors, mGlu2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience 71 (1996) 949-976
32. Pfaffl M.W. Relative quantification. Real Time PCR (BIOS Advanced Methods) (2006), Taylor and Francis 63-82
33. Poschel B., Wroblewska B., Heinemann U., and Manahan-Vaughan D. The metabotropic glutamate receptor mGluR3 is critically required for hippocampal long-term depression and modulates long-term potentiation in the dentate gyrus of freely moving rats. Cereb Cortex 15 (2005) 1414-1423
34. Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol. 32 (1972) 281-294
35. Sambrook J., and Russell D.W. Molecular Cloning, a Laboratory Manual (2001), Cold Spring Harbor Laboratories Press, Cold Spring
36. Sanabria E.R., Wozniak K.M., Slusher B.S., and Keller A. GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism. J Neurophysiol. 91 (2004) 182-193
37. Scanziani M., Salin P.A., Vogt K.E., Malenka R.C., and Nicoll R.A. Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors. Nature 385 (1997) 630-634
38. Shigemoto R., Kinoshita A., Wada E., Nomura S., Ohishi H., Takada M., Flor P.J., Neki A., Abe T., Nakanishi S., and Mizuno N. Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci. 17 (1997) 7503-7522
39. Tamaru Y., Nomura S., Mizuno N., and Shigemoto R. Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre-and postsynaptic sites. Neuroscience 106 (2001) 481-503
40. Tang F.R., and Lee W.L. Expression of the group II and III metabotropic glutamate receptors in the hippocampus of patients with mesial temporal lobe epilepsy. J Neurocytol. 30 (2001) 137-143
41. Tang F.R., Chia S.C., Chen P.M., Gao H., Lee W.L., Yeo T.S., Burgunder J.M., Probst A., Sim M.K., and Ling E.A. Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and mice after pilocarpine-induced status epilepticus. Epilepsy Res. 59 (2004) 167-180
42. Toth K., Suares G., Lawrence J.J., Philips-Tansey E., and McBain C.J. Differential mechanisms of transmission at three types of mossy fiber synapse. J Neurosci. 20 (2000) 8279-8289
43. Turski W.A., Cavalheiro E.A., Bortolotto Z.A., Mello L.M., Schwarz M., and Turski L. Seizures produced by pilocarpine in mice: a behavioral, electroencephalographic and morphological analysis. Brain Res. 321 (1984) 237-253
44. Wheeler G. Gabapentin. Pfizer. Curr Opin Investig Drugs 3 (2002) 470-477
45. Yokoi M., Kobayashi K., Manabe T., Takahashi T., Sakaguchi I., Katsuura G., Shigemoto R., Ohishi H., Nomura S., Nakamura K., Nakao K., Katsuki M., and Nakanishi S. Impairment of hippocampal mossy fiber LTD in mice lacking mGlu2. Science 273 (1996) 645-647