Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain

Journal of Neurophysiology

Volumn 96, Issue 4, 2006, Pages 1803-1815

  Li, Weidong ^a   Neugebauer, Volker ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRAGEENAN; KAOLIN; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EVOKED RESPONSE; KNEE ARTHRITIS; MALE; MICRODIALYSIS; MUSCLE EXCITATION; NERVE CELL; NERVE CELL PLASTICITY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ALANINE; AMINOBUTYRIC ACIDS; AMYGDALA; ANIMALS; ARTHRITIS; BICYCLO COMPOUNDS; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID AGONISTS; GLUTAMATES; MALE; NEURONAL PLASTICITY; NOCICEPTORS; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPTIC TRANSMISSION;

EID: 33749514629     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00495.2006     Document Type: Article

References (76)

1. Anwyl R. Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res Brain Res Rev 29: 83-120, 1999.
2. Berrino L, Oliva P, Rossi F, Palazzo E, Nobili B, and Maione S. Interaction between metabotropic and NMDA glutamate receptors in the periaqueductal grey pain modulatory system. Naunyn Schmiedebergs Arch Pharmacol 364: 437-443, 2001.
3. Bird GC, Lash LL, Han JS, Zou X, Willis WD, and Neugebauer V. PKA-dependent enhanced NMDA receptor function in pain-related synaptic plasticity in amygdala neurons. J Physiol 564: 907-921, 2005.
4. Bordi F and Ugolini A. Group I metabotropic glutamate receptors: implications for brain diseases. Prog Neurobiol 59: 55-79, 1999.
5. Bourgeais L, Gauriau C, and Bernard J-F. Projections from the nociceptive area of the central nucleus of the amygdala to the forebrain: a PHA-L study in the rat. Eur J Neurosci 14: 229-255, 2001.
6. Bradley SR, Rees HD, Yi H, Levey AI, and Conn PJ. Distribution and developmental regulation of metabotropic glutamate receptor 7a in rat brain. J Neurochem 71: 636-645, 1998.
7. Braz JM, Nassar MA, Wood JN, and Basbaum AI. Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron 47: 787-793, 2005.
8. Cartmell J and Schoepp DD. Regulation of neurotransmitter release by metabotropic glutamate receptors. J Neurochem 75: 889-907, 2000.
9. Corti C, Aldegheri L, Somogyi P, and Ferraguti F. Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS. Neuroscience 110: 403-420, 2002.
10. Davidson RJ. Anxiety and affective style: role of prefrontal cortex and amygdala. Biol Psychiatry 51: 68-80, 2002.
11. Davis M. Anatomic and physiologic substrates of emotion in an animal model. J Clin Neurophysiol 15: 378-387, 1998.
12. De Blasi A, Conn PJ, Pin J, and Nicoletti F. Molecular determinants of metabotropic glutamate receptor signaling. Trends Pharmacol Sci 22: 114-120, 2001.
13. Dolan S and Nolan AM. Behavioral evidence supporting a differential role for spinal group I and II metabotropic glutamate receptors in inflammatory hyperalgesia in sheep. Neuropharmacology 43: 319-326, 2002.
14. Duvoisin RM, Zhang C, and Ramonell K. A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J Neurosci 15: 3075-3083, 1995.
15. Ferraguti F, Klausberger T, Cobden P, Baude A, Roberts JD, Szucs P, Kinoshita A, Shigemoto R, Somogyi P, and Dalezios Y. Metabotropic glutamate receptor 8-expressing nerve terminals target subsets of GABAergic neurons in the hippocampus. J Neurosci 25: 10520-10536, 2005.
16. Fundytus ME. Glutamate receptors and nociception. Implications for the drug treatment of pain. CNS Drugs 15: 29-58, 2001.
17. Gallagher RM and Verma S. Mood and anxiety disorders in chronic pain. Prog Pain Res Manage 27: 139-178, 2004.
18. Gasparini F, Kuhn R, and Pin JP. Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives. Curr Opin Pharmacol 2: 43-49, 2002.
19. Gauriau C and Bernard J-F. Pain pathways and parabrachial circuits in the rat. Exp Physiol 87: 251-258, 2002.
20. Gerber G, Zhong J, Youn D, and Randic M. Group II and group III metabotropic glutamate receptor agonists depress synaptic transmission in the rat spinal cord dorsal horn. Neuroscience 100: 393-406, 2000.
21. Grillon C, Cordova J, Levine LR, and Morgan CA III. Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans. Psychopharmacology (Berl) 168: 446-454, 2003.
22. Han JS, Bird GC, Li W, and Neugebauer V. Computerized analysis of audible and ultrasonic vocalizations of rats as a standarized measure of pain-related behavior. Neurosci Methods 141: 261-269, 2005a.
23. Han JS, Bird GC, and Neugebauer V. Enhanced group III mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala. Neuropharmacology 46: 918-926, 2004.
24. Han JS, Li W, and Neugebauer V. Critical role of calcitonin gene-related peptide 1 receptors in the amygdala in synaptic plasticity and pain behavior. J Neurosci 25: 10717-10728, 2005b.
25. Han JS and Neugebauer V. mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain. Pain 113: 211-222, 2005.
26. Jang JH, Kim DW, Sang Nam T, Se Paik K, and Leem JW. Peripheral glutamate receptors contribute to mechanical hyperalgesia in a neuropathic pain model of the rat. Neuroscience 128: 169-176, 2004.
27. Jones CK, Eberle EL, Peters SC, Monn JA, and Shannon HE. Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing. Neuropharmacology 49: 206-218, 2005.
28. Kingston AE, O'Neill MJ, Bond A, Bruno V, Battaglia G, Nicoletti F, Harris JR, Clark BP, Monn JA, Lodge D, and Schoepp DD. Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors. Ann NY Acad Sci 890: 438-449, 1999.
29. Kinoshita A, Shigemoto R, Ohishi H, van der PH, and Mizuno N. Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: a light and electron microscopic study. J Comp Neurol 393: 332-352, 1998.
30. Lesage ASJ. Role of group I metabotropic glutamate receptors mGlu1 and mGlu5 in nociceptive signalling. Curr Neuropharmacol 2: 363-393, 2004.
31. Li W and Neugebauer V. Differential roles of mGluR1 and mGluR5 in brief and prolonged nociceptive processing in central amygdala neurons. J Neurophysiol 91: 13-24, 2004a.
32. Li W and Neugebauer V. Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdala neurons in a model of arthritic pain. Pain 110: 112-122, 2004b.
33. Lujan R, Roberts JD, Shigemoto R, Ohishi H, and Somogyi P. Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites. J Chem Neuroanat 13: 219-241, 1997.
34. Maione S, Marabese I, Leyva J, Palazzo E, de Novellis V, and Rossi F. Characterisation of mGluRs which modulate nociception in the PAG of the mouse. Neuropharmacology 37: 1475-1483, 1998.
35. Maione S, Oliva P, Marabese I, Palazzo E, Rossi F, Berrino L, Rossi F, and Filippelli A. Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception. Pain 85: 183-189, 2000.
36. Marek GJ. Metabotropic glutamate 2/3 receptors as drug targets. Curr Opin Pharmacol 4: 18-22, 2004.
37. Maren S. Synaptic mechanisms of associative memory in the amygdala. Neuron 47: 783-786, 2005.
38. McGaraughty S and Heinricher MM. Microinjection of morphine into various amygdaloid nuclei differentially affects nociceptive responsiveness and RVM neuronal activity. Pain 96: 153-162, 2002.
39. Min SS, Han JS, Kim YI, Na HS, Yoon YW, Hong SK, and Han HC. A novel method for convenient assessment of arthritic pain in voluntarily walking rats. Neurosci Lett 308: 95-98, 2001.
40. Nakanishi S, Nakajima Y, Masu M, Yoshiki U, Nakahara K, Watanabe D, Yamaguchi S, Kawabata S, and Okada M. Glutamate receptors: brain function and signal transduction. Brain Res Rev 26: 230-235, 1998.
41. Neto FL and Castro-Lopes JM. Antinociceptive effect of a group II metabotropic glutamate receptor antagonist in the thalamus of monoarthritic rats. Neurosci Lett 296: 25-28, 2000.
42. Neugebauer V. Metabotropic glutamate receptors: novel targets for pain relief. Expert Rev Neurotherapeut 1: 207-224, 2001.
43. Neugebauer V. Metabotropic glutamate receptors - important modulators of nociception and pain behavior. Pain 98: 1-8, 2002.
44. Neugebauer V and Carlton SM. Peripheral metabotropic glutamate receptors as drug targets for pain relief. Exp Opin Ther Targets 6: 349-361, 2002.
45. Neugebauer V, Chen P-S, and Willis WD. Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells. J Neurophysiol 84: 2998-3009, 2000a.
46. Neugebauer V, Keele NB, and Shinnick-Gallagher P. Epileptogenesis in vivo enhances the sensitivity of inhibitory presynaptic metabotropic glutamate receptors in basolateral amygdala neurons in vitro. J Neurosci 17: 983-995, 1997.
47. Neugebauer V and Li W. Processing of nociceptive mechanical and thermal information in central amygdala neurons with knee-joint input. J Neurophysiol 87: 103-112, 2002.
48. Neugebauer V and Li W. Differential sensitization of amygdala neurons to afferent inputs in a model of arthritic pain. J Neurophysiol 89: 716-727, 2003.
49. Neugebauer V, Li W, Bird GC, Bhave G, and Gereau RW. Synaptic plasticity in the amygdala in a model of arthritic pain: differential roles of metabotropic glutamate receptors 1 and 5. J Neurosci 23: 52-63, 2003.
50. Neugebauer V, Li W, Bird GC, and Han JS. The amygdala and persistent pain. Neuroscientist 10: 221-234, 2004.
51. Neugebauer V, Zinebi F, Russell R, Gallagher JP, and Shinnick-Gallagher P. Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala. J Neurophysiol 84: 759-770, 2000b.
52. Ohishi H, Akazawa C, Shigemoto R, Nakanishi S, and Mizuno N. Distributions of the mRNAs for L-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain. J Comp Neurol 360: 555-570, 1995.
53. Ohishi H, Neki A, and Mizuno N. Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: an immunohistochemical study with a monoclonal antibody. Neurosci Res 30: 65-82, 1998.
54. Ohishi H, Shigemoto R, Nakanishi S, and Mizuno N. Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat. Neuroscience 53: 1009-1018, 1993a.
55. Ohishi H, Shigemoto R, Nakanishi S, and Mizuno N. Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study. J Comp Neurol 335: 252-266, 1993b.
56. Paré D, Quirk GJ, and Ledoux JE. New vistas on amygdala networks in conditioned fear. J Neurophysiol 92: 1-9, 2004.
57. Paxinos G and Watson C. The Rat Brain in Stereotaxic Coordinates. New York: Academic Press, 1998.
58. Phelps EA and Ledoux JE. Contributions of the amygdala to emotion processing: from animal models to human behavior. Neuron 48: 175-187, 2005.
59. Price JL. Comparative aspects of amygdala connectivity. In: The Amygdala in Brain Function. Basic and Clinical Approaches, edited by Shinnick-Gallagher P, Pitkanen A, Shekhar A, and Cahill L. New York: The New York Academy of Sciences, 2003, p. 50-58.
60. Rhudy JL and Meagher MW. The role of emotion in pain modulation. Curr Opin Psychiatry 14: 241-245, 2001.
61. Rodrigues SM, Schafe GE, and Ledoux JE. Molecular mechanisms underlying emotional learning and memory in the lateral amygdala. Neuron 44: 75-91, 2004.
62. Rome HP Jr and Rome JD. Limbically augmented pain syndrome (LAPS): kindling, corticolimbic sensitization, and the convergence of affective and sensory symptoms in chronic pain disorders. Pain Med 1: 7-23, 2000.
63. Salt TE. Glutamate receptor functions in sensory relay in the thalamus. Philos Trans R Soc Lond B Biol Sci 357: 1759-1766, 2002.
64. Saugstad JA, Kinzie JM, Shinohara MM, Segerson TP, and Westbrook GL. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Mol Pharmacol 51: 119-125, 1997.
65. Schoepp DD, Jane DE, and Monn JA. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38: 1431-1476, 1999.
66. Shigemoto R, Kinoshita A, Wada E, Nomura S, Ohishi H, Takada M, Flor PJ, Neki A, Abe T, Nakanishi S, and Mizuno N. Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J Neurosci 17: 7503-7522, 1997.
67. Simmons RM, Webster AA, Kalra AB, and Iyengar S. Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats. Pharmacol Biochem Behav 73: 419-427, 2002.
68. Soliman AC, Yu JSC, and Coderre TJ. mGlu and NMDA receptor contributions to capsaicin-induced thermal and mechanical hypersensitivity. Neuropharmacology 48: 325-332, 2005.
69. Stanfa LC and Dickenson AH. Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. Eur J Pharmacol 347: 165-172, 1998.
70. Swanson CJ, Bures M, Johnson MP, Linden AM, Monn JA, and Schoepp DD. Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat Rev Drug Discov 4: 131-144, 2005.
71. Varney MA and Gereau RW. Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics. Current Drug Targets 1: 215-225, 2002.
72. Walker DL and Davis M. Are fear memories made and maintained by the same NMDA receptor-dependent mechanisms? Neuron 41: 781-793, 2004.
73. Walker DL, Rattiner LM, and Davis M. Group II metabotropic glutamate receptors within the amygdala regulate fear as assessed with potentiated startle in rats. Behav Neurosci 116: 1075-1083, 2002.
74. Yang D and Gereau RW. Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. J Neurosci 22: 6388-6393, 2002.
75. Yang D and Gereau RW. Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation. Pain 106: 411-417, 2003.
76. Zald DH. The human amygdala and the emotional evaluation of sensory stimuli. Brain Res Rev 41: 88-123, 2003.