Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice

Journal of Neuroscience

Volumn 26, Issue 24, 2006, Pages 6573-6582

  Callaerts Vegh, Zsuzsanna ^a   Beckers, Tom ^a   Ball, Simon M ^b   Baeyens, Frank ^a   Callaerts, Patrick F ^c   Cryan, John F ^d,f   Molnar, Elek ^b   D'Hooge, Rudi ^a,e  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d NOVARTIS PHARMA AG   (Switzerland)

^e Lab of Experimental Radiotherapy   (Belgium)

^f UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Conditioned emotional response; Fear and anxiety; Fear extinction; Learning and memory; Metabotropic glutamate receptors; Operant

Indexed keywords

AMPA RECEPTOR; METABOTROPIC RECEPTOR 7; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; METABOTROPIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; BEHAVIOR; CONDITIONING; CONTROLLED STUDY; EMOTION; FEAR; LEARNING; MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TASK PERFORMANCE; WORKING MEMORY; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; ANXIETY; AVOIDANCE BEHAVIOR; C57BL MOUSE; COMPARATIVE STUDY; DISEASE MODEL; EVOKED VISUAL RESPONSE; EXPLORATORY BEHAVIOR; FEMALE; GENE EXPRESSION; GENETICS; HUMAN RELATION; IMMUNOHISTOCHEMISTRY; INSTRUMENTAL CONDITIONING; MALE; METABOLISM; MOTOR ACTIVITY; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PSYCHOMOTOR PERFORMANCE; REINFORCEMENT; SHORT TERM MEMORY;

ANALYSIS OF VARIANCE; ANIMALS; ANXIETY; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS, VISUAL; EXPLORATORY BEHAVIOR; EXTINCTION, PSYCHOLOGICAL; FEAR; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTERPERSONAL RELATIONS; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; PSYCHOMOTOR PERFORMANCE; RECEPTORS, AMPA; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 33745781189     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1497-06.2006     Document Type: Article

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