A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1α metabotropic glutamate receptors

Journal of Chemical Neuroanatomy

Volumn 13, Issue 2, 1997, Pages 77-93

  Petralia, Ronald S ^a   Wang, Ya Xian ^a   Singh, Sujay ^b,c   Wu, Chun ^b   Shi, Liangru ^b   Wei, Jia ^b   Wenthold, Robert J ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b BD Technologies   (United States)

^c General Instrument Corporation   (United States)

Author keywords

Cerebellum; Dorsal cochlear nucleus; Hippocampus; Interneuron; Motoneurons; Purkinje cell; Spinal cord

Indexed keywords

METABOTROPIC RECEPTOR; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL ORGANELLE; CELLULAR DISTRIBUTION; COCHLEAR NUCLEUS; CYTOPLASM; ENDOPLASMIC RETICULUM; GLOBUS PALLIDUS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; INTERNEURON; MOUSE; NERVE CELL MEMBRANE; NONHUMAN; OLFACTORY BULB; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; THALAMUS; ULTRASTRUCTURE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BRAIN CHEMISTRY; ENDOPLASMIC RETICULUM; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; PURKINJE CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0030777350     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-0618(97)00023-9     Document Type: Article

References (49)

1. Batchelor, A.M., Madge, D.J., Garthwaite, J., 1994. Synaptic activation of metabotropic glutamate receptors in the parallel fibre-Purkinje cell pathway in rat cerebellar slices. Neuroscience 63, 911-915.
2. Baude, A., Nusser, Z., Roberts, J.D.B., Mulvihill, E., McIlhinney, R.A.J., Somogyi, P., 1993. The metabotropic glutamate receptor (mGluR1α) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11, 771-787.
3. Baude, A., Nusser, Z., Molnár, E., McIlhinney, R.A.J., Somogyi, P., 1995. High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus. Neuroscience 69, 1031-1055.
4. Conquet, F., Bashir, Z.I., Davies, C.H., Daniel, H., Ferraguti, F., Bordi, F., Franz-Bacon, K., Reggiani, A., Matarese, V., Condé, F., Collingridge, G.L., Crépel, F., 1994. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature 372, 237-243.
5. Eshhar, N., Petralia, R.S., Winters, C.A., Niedzielski, A.S., Wenthold, R.J., 1993. The segregation and expression of glutamate receptor subunits in cultured hippocampal neurons. Neuroscience 57, 943-964.
6. Fotuhi, M., Sharp, A.M., Glatt, C.E., Hwang, P.M., von Krosigk, M., Snyder, S.H., Dawson, T.M., 1993. Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain. J. Neurosci. 13, 2001-2012.
7. Galfre, G., Howe, S.C., Milstein, C., Butcher, G.W., Howard, J.C., 1977. Antibodies to major histocompatibility antigens produced by hybrid cell line. Nature 266, 550-552.
8. Göres, T.J., Penke, B., Boti, Z., Katarova, Z., Hamori, J., 1993. Immunohistochemical visualization of a metabotropic glutamate receptor. NeuroReport 4, 283-286.
9. Hampson, D.R., Theriault, E., Huang, X.-P., Kristensen, P., Pickering, D.S., Franck, J.E., Mulvihill, E.R., 1994. Characterization of two alternatively spliced forms of a metabotropic glutamate receptor in the central nervous system of the rat. Neuroscience 60, 325-336.
10. Houamed, K.M., Kuijper, J.L., Gilbert, T.L., Haldeman, B.A., O'Hara, P.J., Mulvihill, E.R., Almers, W., Hagen, F.S., 1991. Cloning, expression and gene structure of a G protein-coupled glutamate receptor from rat brain. Science 252, 1318-1321.
11. Kharazia, V.N., Wenthold, R.J., Weinberg, R.J., 1996. GluR1-immunopositive interneurons in rat neocortex. J. Comp. Neurol. 368, 399-412.
12. 1d, a novel splice variant of the human type I metabotropic glutamate receptor. Eur. J. Pharmacol. 296, R1-R3.
13. Leranth, C., Szeidemann, Z., Hsu, M., Buzsáki, G., 1996. AMPA receptors in the rat and primate hippocampus: A possible absence of GluR2/3 subunits in most interneurons. Neuroscience 70, 631-652.
14. Luján, R., Nusser, Z., Roberts, J.D.B., Shigemoto, R., Somogyi, P., 1996. Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus. Eur. J. Neurosci. 8, 1488-1500.
15. Martin, L.J., Blackstone, C.D., Huganir, R.L., Price, D.L., 1992. Cellular localization of a metabotropic glutamate receptor in the rat brain. Neuron 9, 259-270.
16. Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., Nakanishi, S., 1991. Sequence and expression of a metabotropic glutamate receptor. Nature 349, 760-765.
17. Mayat, E., Petralia, R.S., Wang, Y.-X., Wenthold, R.J., 1995. Immunoprecipitation, immunoblotting and immunocytochemistry studies suggest that glutamate receptor delta subunits form novel postsynaptic receptor complexes. J. Neurosci. 15, 2533-2546.
18. McCormick, D.A., Von Krosigk, M., 1992. Corticothalamic activation modulates thalamic firing through glutamate 'metabotropic' receptors. Proc. Natl. Acad. Sci. USA 89, 2774-2778.
19. Molnár, E., Baude, A., Richmond, S.A., Patel, P.B., Somogyi, P., McIlhinney, R.A.J., 1993. Biochemical and immunocytochemical characterization of antipeptide antibodies to a cloned GluR1 glutamate receptor subunit: Cellular and subcellular distribution in the rat forebrain. Neuroscience 53, 307-326.
20. Nakanishi, S., 1994. Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity. Neuron 13, 1031-1037.
21. Nusser, Z., Mulvhill, E., Streit, P., Somogyi, P., 1994. Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neuroscience 61, 421-427.
22. Patton, J.G., Alley, M.C., Mao, S.J., 1982. Evaluation of monoclonal antibodies to human plasma low density lipoproteins. A requirement for lipids to maintain antigenic structure. J. Immunol. Meth. 55, 193-203.
23. Paxinos, G., Watson, C., 1986. The Rat Brain in Stereotaxic Coordinates, Academic, New York.
24. Petralia, R.S., 1997. Immunocytochemical localization of ionotropic glutamate receptors in neural circuits. In: Monaghan, D.T., Wenthold, R.J. (Eds.), The Ionotropic Glutamate Receptors. Humana, Totowa, N.J., pp. 219-263.
25. Petralia, R.S., Wenthold, R.J., 1992. Light and electron immunocytochemical localization of AMPA-selective glutamate receptors in the rat brain. J. Comp. Neurol. 318, 329-354.
26. Petralia, R.S., Wenthold, R.J., 1996. Types of excitatory amino acid receptors and their localization in the nervous system and hypothalamus. In: Brann, D.W., Mahesh, V.B. (Eds.), Excitatory Amino Acids: Their Role in Neuroendocrine Function. CRC, Boca Raton, FL, pp. 55-101.
27. Petralia, R.S., Yokotani, N., Wenthold, R.J., 1994a. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14, 667-696.
28. Petralia, R.S., Wang, Y.-X., Wenthold, R.J., 1994b. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J. Neurosci. 14, 6102-6120.
29. Petralia, R.S., Wang, Y.-X., Wenthold, R.J., 1994c. Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodies. J. Comp. Neurol. 349, 85-110.
30. Petralia, R.S., Wang, Y.-X., Niedzielski, A.S., Wenthold, R.J., 1996a. The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience 71, 949-976.
31. Petralia, R.S., Wang, Y.-X., Zhao, H.-M., Wenthold, R.J., 1996b. Ionotropic and metabotropic glutamate receptors show unique postsynaptic, presynaptic, and glial localizations in the dorsal cochlear nucleus. J. Comp. Neurol. 372, 356-383.
32. Petralia, R.S., Wang, Y.-X., Mayat, E., Wenthold, R.J., 1997. A GluR2-selective antibody shows a differential distribution of calcium-impermeable AMPA receptors among populations of neurons. J. Comp. Neurol. in press.
33. Pin, J.-P., Bockaert, J., 1995. Get receptive to metabotropic glutamate receptors. Curr. Opin. Neurobiol. 5, 342-349.
34. Pin, J.-P., Duvoisin, R., 1995. The metabotropic glutamate receptors: Structure and functions. Neuropharmacology 34, 1-26.
35. Reid, S.N.M., Romano, C., Hughes, T., Daw, N.W., 1995. Immunohistochemical study of two phosphoinositide-linked metabotropic glutamate receptors (mGluRla and mGluR5) in the cat visual cortex before, during and after the peak of the critical period for eye-specific connections. J. Comp. Neurol. 355, 470-477.
36. Ribak, C.E., Seress, L., 1983. Five types of basket cell in the hippocampal dentate gyrus: A combined Golgi and electron microscopic study. J. Neurocytol. 12, 577-597.
37. Romano, C., Sesma, M.A., MacDonald, C., O'Malley, K., van den Pol, A., Olney, J.W., 1995. Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J. Comp. Neurol. 355, 455-469.
38. Seress, L., Ribak, C.E., 1985. A combined Golgi-electron microscopic study of non-pyramidal neurons in the CA1 area of the hippocampus. J. Neurocytol. 14, 717-730.
39. Shigemoto, R., Nakanishi, S., Mizuno, N., 1992. Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat. J. Comp. Neurol. 322, 121-135.
40. Shigemoto, R., Kulik, A., Roberts, J.D.B., Ohishi, H., Nusser, Z., Kaneko, T., Somogyi, P., 1996. Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone. Nature 381, 523-525.
41. Smith, D.B., Johnson, K.S., 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67, 31-40.
42. Soriano, E., Frotscher, M., 1993. Spiny nonpyramidal neurons in the CA3 region of the rat hippocampus are glutamate-like immunoreactive and receive convergent mossy fiber input. J. Comp. Neurol. 332, 435-448.
43. Testa, C.M., Standaert, D.G., Young, A.B., Penney, J.B. Jr., 1994. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J. Neurosci. 14, 3005-3018.
44. van den Pol, A.N., 1994. Metabotropic glutamate receptor mGluR1 distribution and ultrastructural localization in hypothalamus. J. Comp. Neurol. 349, 615-632.
45. van den Pol, A.N., 1995. Presynaptic metabotropic glutamate receptors in adult and developing neurons: Autoexcitation in the olfactory bulb. J. Comp. Neurol. 359, 253-271.
46. Vidnyánszky, Z., Göres, T.J., Négyessy, L., Borostyánkõi, Z., Kuhn, R., Knöpfel, T., Hámori, J., 1996. Immunocytochemical visualization of the mGluRla metabotropic glutamate receptor at synapses of corticothalamic terminals originating from area 17 of the rat. Eur. J. Neurosci. 8, 1061-1071.
47. Wenthold, R.J., Trumpy, V.A., Zhu, W.S., Petralia, R.S., 1994. Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies. J. Biol. Chem. 269, 1332-1339.
48. Wright, D.D., Blackstone, C.D., Huganir, R.L., Ryugo, D.K., 1996. Immunocytochemical localization of the mGluR1α metabotropic glutamate receptor in the dorsal cochlear nucleus. J. Comp. Neurol. 364, 729-745.
49. Zhao, H.-M., Wenthold, R.J., Wang, Y.-X., Petralia, R.S., 1997. Delta glutamate receptors are differentially distributed at parallel and climbing fiber synapses on Purkinje cells. J. Neurochem. 68, 1041-1052.