Adenosine A2A Receptors Are Essential for Long-Term Potentiation of NMDA-EPSCs at Hippocampal Mossy Fiber Synapses

Neuron

Volumn 57, Issue 1, 2008, Pages 121-134

  Rebola, Nelson ^a,c   Lujan, Rafael ^b   Cunha, Rodrigo A ^a   Mulle, Christophe ^c  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^c University of Bordeaux   (France)

Author keywords

CELLBIO; SIGNALING; SYSNEURO

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENOSINE A2A RECEPTOR; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; CALCIUM; DRUG DERIVATIVE; ENZYME INHIBITOR; N METHYLASPARTIC ACID; PHENETHYLAMINE DERIVATIVE; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MEMORY; MOSSY FIBER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; RECEPTOR INTRINSIC ACTIVITY; SYNAPSE; SYNAPTIC TRANSMISSION; ANIMAL; C57BL MOUSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; DRUG POTENTIATION; ELECTROSTIMULATION; IN VITRO STUDY; METABOLISM; METHODOLOGY; NEWBORN; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ADENOSINE; ANIMALS; ANIMALS, NEWBORN; CALCIUM; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG INTERACTIONS; ELECTRIC STIMULATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; LONG-TERM POTENTIATION; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MOSSY FIBERS, HIPPOCAMPAL; N-METHYLASPARTATE; PHENETHYLAMINES; PYRIMIDINES; RECEPTOR, ADENOSINE A2A; SYNAPSES; TRIAZOLES;

EID: 37549021899     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2007.11.023     Document Type: Article

References (42)

1. Bashir Z.I., Alford S., Davies S.N., Randall A.D., and Collingridge G.L. Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus. Nature 349 (1991) 156-158
2. Ciruela F., Casado V., Rodrigues R.J., Lujan R., Burgueno J., Canals M., Borycz J., Rebola N., Goldberg S.R., Mallol J., et al. Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. J. Neurosci. 26 (2006) 2080-2087
3. 2A facilitatory adenosine receptor activation balance depends on motor nerve stimulation paradigm at the rat hemidiaphragm. J. Neurophysiol. 76 (1996) 3910-3919
4. Cunha R.A. Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors. Neurochem. Int. 38 (2001) 107-125
5. 2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices. J. Neurosci. 24 (2004) 2905-2913
6. Dunwiddie T.V., and Masino S.A. The role and regulation of adenosine in the central nervous system. Annu. Rev. Neurosci. 24 (2001) 31-55
7. Fredholm B.B., Chen J.F., Cunha R.A., Svenningsson P., and Vaugeois J.M. Adenosine and brain function. Int. Rev. Neurobiol. 63 (2005) 191-270
8. Frenguelli B.G., Wigmore G., Llaudet E., and Dale N. Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus. J. Neurochem. 101 (2007) 1400-1413
9. Harney S.C., Rowan R., and Anwyl R. Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering. J. Neurosci. 26 (2006) 1128-1132
10. Henze D.A., Urban N.N., and Barrionuevo G. The multifarious hippocampal mossy fiber pathway: a review. Neuroscience 98 (2000) 407-427
11. Henze D.A., Wittner L., and Buzsaki G. Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo. Nat. Neurosci. 5 (2002) 790-795
12. Heynen A.J., Quinlan E.M., Bae D.C., and Bear M.F. Bidirectional, activity-dependent regulation of glutamate receptors in the adult hippocampus in vivo. Neuron 28 (2000) 527-536
13. Kishimoto Y., Nakazawa K., Tonegawa S., Kirino Y., and Kano M. Hippocampal CA3 NMDA receptors are crucial for adaptive timing of trace eyeblink conditioned response. J. Neurosci. 26 (2006) 1562-1570
14. Kotecha S.A., and MacDonald J.F. Signaling molecules and receptor transduction cascades that regulate NMDA receptor-mediated synaptic transmission. Int. Rev. Neurobiol. 54 (2003) 51-106
15. Kotecha S.A., Jackson M.F., Al-Mahrouki A., Roder J.C., Orser B.A., and MacDonald J.F. Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons. J. Biol. Chem. 278 (2003) 27742-27749
16. Kukley M., Schwan M., Fredholm B.B., and Dietrich D. The role of extracellular adenosine in regulating mossy fiber synaptic plasticity. J. Neurosci. 25 (2005) 2832-2837
17. Lei S., Pelkey K.A., Topolnik L., Conger P., Lacaille J.C., and Mcbain C.J. Depolarization-induced long-term depression at hippocampal mossy fiber-CA3 pyramidal neuron synapses. J. Neurosci. 23 (2003) 9786-9795
18. Liao D., Hessler N.A., and Malinow R. Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature 375 (1995) 400-404
19. 1 receptor inhibition. Neuroscience 112 (2002) 319-329
20. Luján R., Nusser Z., Roberts J.D.B., Shigemoto R., and Somogyi P. Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus. Eur. J. Neurosci. 8 (1996) 1488-1500
21. Macdonald D.S., Weerapura M., Beazely M.A., Martin L., Czerwinski W., Roder J.C., Orser B.A., and MacDonald J.F. Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. J. Neurosci. 25 (2005) 11374-11384
22. Malenka R.C., and Bear M.F. LTP and LTD: An embarrassment of riches. Neuron 44 (2004) 5-21
23. Marchal C., and Mulle C. Postnatal maturation of mossy fibre excitatory transmission in mouse CA3 pyramidal cells: a potential role for kainate receptors. J. Physiol. 561 (2004) 27-37
24. Marino M.J., Rouse S.T., Levey A.I., Potter L.T., and Conn P.J. Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells. Proc. Natl. Acad. Sci. USA 95 (1998) 11465-11470
25. Moore K.A., Nicoll R.A., and Schmitz D. Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses. Proc. Natl. Acad. Sci. USA 100 (2003) 14397-14402
26. Nakazawa K., Quirk M.C., Chitwood R.A., Watanabe M., Yeckel M.F., Sun L.D., Kato A., Carr C.A., Johnston D., Wilson M.A., and Tonegawa S. Requirement for hippocampal CA3 NMDA receptors in associative memory recall. Science 297 (2002) 211-218
27. Nakazawa K., Sun L.D., Quirk M.C., Rondi-Reig L., Wilson M.A., and Tonegawa S. Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience. Neuron 38 (2003) 305-315
28. Nicoll R.A., and Schmitz D. Synaptic plasticity at hippocampal mossy fibre synapses. Nat. Rev. Neurosci. 6 (2005) 863-876
29. O'Connor J.J., Rowan M.J., and Anwyl R. Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation. Nature 367 (1994) 557-559
30. O'Connor J.J., Rowan M.J., and Anwyl R. Tetanically induced LTP involves a similar increase in the AMPA and NMDA receptor components of the excitatory postsynaptic current: investigations of the involvement of mGlu receptors. J. Neurosci. 15 (1995) 2013-2020
31. Pascual O., Casper K.B., Kubera C., Zhang J., Revilla-Sanchez R., Sul J.Y., Takano H., Moss S.J., McCarthy K., and Haydon P.G. Astrocytic purinergic signaling coordinates synaptic networks. Science 310 (2005) 113-116
32. 2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation. Neuron 11 (1993) 817-823
33. Pinheiro P.S., Perrais D., Coussen F., Barhanin J., Bettler B., Mann J.R., Malva J.O., Heinemann S.F., and Mulle C. GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proc. Natl. Acad. Sci. USA 104 (2007) 12181-12186
34. 2A receptors control the extracellular levels of adenosine through modulation of nucleoside transporters activity in the rat hippocampus. J. Neurochem. 93 (2005) 595-604
35. Rajji T., Chapman D., Eichenbaum H., and Greene R. The role of CA3 hippocampal NMDA receptors in paired associate learning. J. Neurosci. 26 (2006) 908-915
36. 2A receptors in the hippocampus and striatum of the rat. Neuroscience 132 (2005) 893-903
37. Rebola N., Sachidhanandam S., Perrais D., Cunha R.A., and Mulle C. Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses. J. Neurosci. 27 (2007) 3987-3993
38. Salter M.W., and Kalia L.V. Src kinases: a hub for NMDA receptor regulation. Nat. Rev. Neurosci. 5 (2004) 317-328
39. Tebano M.T., Martire A., Rebola N., Pepponi R., Domenici M.R., Gro M.C., Schwarzschild M.A., Chen J.F., Cunha R.A., and Popoli P. Adenosine A2A receptors and mGluR5 are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects. J. Neurochem. 95 (2005) 1188-1200
40. Wirkner K., Gerevich Z., Krause T., Gunther A., Koles L., Schneider D., Norenberg W., and Illes P. Adenosine A2A receptor-induced inhibition of NMDA and GABAA receptor-mediated synaptic currents in a subpopulation of rat striatal neurons. Neuropharmacology 46 (2004) 994-1007
41. Yeckel M.F., Kapur A., and Johnston D. Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism. Nat. Neurosci. 2 (1999) 625-633
42. Zalutsky R.A., and Nicoll R.A. Comparison of two forms of long-term potentiation in single hippocampal neurons. Science 251 (1990) 1619-1624