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Volumn 73, Issue 2, 2002, Pages 455-466

Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease

(7) Murray, Tracey K a Messenger, Marcus J b Ward, Mark A a Woodhouse, Sandra a Osborne, David J a Duty, Susan b O'Neill, Michael J a

a ELI LILLY AND COMPANY (United States)

b KING'S COLLEGE LONDON (United Kingdom)

Author keywords

6 Hydroxydopamine; Akinesia; Glutamate; LY379268; Metabotropic glutamate receptor; Neuroprotection; Parkinson's disease; Reserpine

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; EGLUMETAD; METABOTROPIC RECEPTOR AGONIST; OXIDOPAMINE; RESERPINE; TYROSINE; ADRENERGIC RECEPTOR BLOCKING AGENT; AMINO ACID; AMINO ACID RECEPTOR STIMULATING AGENT; ANTIPARKINSON AGENT; FUSED HETEROCYCLIC RINGS; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; TYROSINE 3 MONOOXYGENASE;

AKINESIA; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG ACTIVITY; DRUG SELECTIVITY; IMMUNOREACTIVITY; LOCOMOTION; MALE; MEASUREMENT; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA; ANIMAL; ANIMAL BEHAVIOR; CHEMICAL SYMPATHECTOMY; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; DRUG POTENTIATION; DYSKINESIA; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; MOTOR ACTIVITY; NEOSTRIATUM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STEREOTYPY;

AMINO ACIDS; ANIMAL; ANTIPARKINSON AGENTS; BEHAVIOR, ANIMAL; BICYCLO COMPOUNDS, HETEROCYCLIC; DYSKINESIA, DRUG-INDUCED; EXCITATORY AMINO ACID AGONISTS; INJECTIONS, INTRAVENTRICULAR; MALE; MOTOR ACTIVITY; NEOSTRIATUM; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RESERPINE; STEREOTYPED BEHAVIOR; SUBSTANTIA NIGRA; SYMPATHECTOMY, CHEMICAL; SYMPATHOLYTICS; TYROSINE 3-MONOOXYGENASE; ANIMALS;

ANIMALIA; RODENTIA;

EID: 0035996544 PISSN: 00913057 EISSN: None Source Type: Journal
DOI: 10.1016/S0091-3057(02)00842-0 Document Type: Article

Times cited : (82)

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