-
1
-
-
23944511133
-
Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons
-
Antar L.N., et al. Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons. Genes Brain Behav. 4 (2005) 350-359
-
(2005)
Genes Brain Behav.
, vol.4
, pp. 350-359
-
-
Antar, L.N.1
-
2
-
-
33744966575
-
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses
-
Antar L.N., et al. Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses. Mol. Cell. Neurosci. 32 (2006) 37-48
-
(2006)
Mol. Cell. Neurosci.
, vol.32
, pp. 37-48
-
-
Antar, L.N.1
-
3
-
-
17844372504
-
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
-
Bagni C., and Greenough W.T. From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat. Rev., Neurosci. 6 (2005) 376-387
-
(2005)
Nat. Rev., Neurosci.
, vol.6
, pp. 376-387
-
-
Bagni, C.1
Greenough, W.T.2
-
4
-
-
0028246435
-
Fmr1 knockout mice: a model to study fragile X mental retardation
-
Bakker C.E., et al. Fmr1 knockout mice: a model to study fragile X mental retardation. Cell 78 (1994) 23-33
-
(1994)
Cell
, vol.78
, pp. 23-33
-
-
Bakker, C.E.1
-
5
-
-
33645993912
-
The fragile X syndrome: exploring its molecular basis and seeking a treatment
-
Bardoni B., et al. The fragile X syndrome: exploring its molecular basis and seeking a treatment. Expert Rev. Mol. Med. 8 (2006) 1-16
-
(2006)
Expert Rev. Mol. Med.
, vol.8
, pp. 1-16
-
-
Bardoni, B.1
-
6
-
-
3042647610
-
The mGluR theory of fragile X mental retardation
-
Bear M.F., et al. The mGluR theory of fragile X mental retardation. Trends Neurosci. 27 (2004) 370-377
-
(2004)
Trends Neurosci.
, vol.27
, pp. 370-377
-
-
Bear, M.F.1
-
7
-
-
0033802736
-
FMRP involvement in formation of synapses among cultured hippocampal neurons
-
Braun K., and Segal M. FMRP involvement in formation of synapses among cultured hippocampal neurons. Cereb. Cortex 10 (2000) 1045-1052
-
(2000)
Cereb. Cortex
, vol.10
, pp. 1045-1052
-
-
Braun, K.1
Segal, M.2
-
8
-
-
0035478371
-
Endogenous activation of group-I metabotropic glutamate receptors is required for differentiation and survival of cerebellar Purkinje cells
-
Catania M.V., et al. Endogenous activation of group-I metabotropic glutamate receptors is required for differentiation and survival of cerebellar Purkinje cells. J. Neurosci. 21 (2001) 7664-7673
-
(2001)
J. Neurosci.
, vol.21
, pp. 7664-7673
-
-
Catania, M.V.1
-
9
-
-
0030986183
-
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits
-
Comery T.A., et al. Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 5401-5404
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 5401-5404
-
-
Comery, T.A.1
-
10
-
-
0036889389
-
Transport of fragile X mental retardation protein via granules in neurites of PC12 cells
-
De Diego Otero Y., et al. Transport of fragile X mental retardation protein via granules in neurites of PC12 cells. Mol. Cell Biol. 22 (2002) 8332-8341
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 8332-8341
-
-
De Diego Otero, Y.1
-
11
-
-
37049032616
-
Correction of fragile X syndrome in mice
-
Dolen G., et al. Correction of fragile X syndrome in mice. Neuron 56 (2007) 955-962
-
(2007)
Neuron
, vol.56
, pp. 955-962
-
-
Dolen, G.1
-
12
-
-
2042473496
-
Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice
-
Frankland P.W., et al. Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice. Mol. Psychiatry 9 (2004) 417-425
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 417-425
-
-
Frankland, P.W.1
-
13
-
-
20044388939
-
Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome
-
Galvez R., and Greenough W.T. Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. Am. J. Med. Genet A. 135 (2005) 155-160
-
(2005)
Am. J. Med. Genet A.
, vol.135
, pp. 155-160
-
-
Galvez, R.1
Greenough, W.T.2
-
14
-
-
0032929398
-
Intracerebral administration of metabotropic glutamate receptor agonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats
-
Grauer S.M., and Marquis K.L. Intracerebral administration of metabotropic glutamate receptor agonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats. Psychopharmacology (Berl). 141 (1999) 405-412
-
(1999)
Psychopharmacology (Berl).
, vol.141
, pp. 405-412
-
-
Grauer, S.M.1
Marquis, K.L.2
-
15
-
-
0035912771
-
Synaptic regulation of protein synthesis and the fragile X protein
-
Greenough W.T., et al. Synaptic regulation of protein synthesis and the fragile X protein. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 7101-7106
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 7101-7106
-
-
Greenough, W.T.1
-
16
-
-
33746196574
-
Local protein synthesis and spine morphogenesis: fragile X syndrome and beyond
-
Grossman A.W., et al. Local protein synthesis and spine morphogenesis: fragile X syndrome and beyond. J. Neurosci. 26 (2006) 7151-7155
-
(2006)
J. Neurosci.
, vol.26
, pp. 7151-7155
-
-
Grossman, A.W.1
-
17
-
-
0036945935
-
The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity
-
Henry S.A., et al. The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity. Neuropharmacology. 43 (2002) 1199-1209
-
(2002)
Neuropharmacology.
, vol.43
, pp. 1199-1209
-
-
Henry, S.A.1
-
18
-
-
0025720084
-
Analysis of neocortex in three males with the fragile X syndrome
-
Hinton V.J., et al. Analysis of neocortex in three males with the fragile X syndrome. Am. J. Med. Genet. 41 (1991) 289-294
-
(1991)
Am. J. Med. Genet.
, vol.41
, pp. 289-294
-
-
Hinton, V.J.1
-
19
-
-
0034685813
-
Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression
-
Huber K.M., et al. Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression. Science 288 (2000) 1254-1257
-
(2000)
Science
, vol.288
, pp. 1254-1257
-
-
Huber, K.M.1
-
20
-
-
0037188502
-
Altered synaptic plasticity in a mouse model of fragile X mental retardation
-
Huber K.M., et al. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 7746-7750
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7746-7750
-
-
Huber, K.M.1
-
21
-
-
0036796924
-
Monitoring kinetic and frequency-domain properties of eyelid responses in mice with magnetic distance measurement technique
-
Koekkoek S.K., et al. Monitoring kinetic and frequency-domain properties of eyelid responses in mice with magnetic distance measurement technique. J. Neurophysiol. 88 (2002) 2124-2133
-
(2002)
J. Neurophysiol.
, vol.88
, pp. 2124-2133
-
-
Koekkoek, S.K.1
-
22
-
-
23044503253
-
Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome
-
Koekkoek S.K., et al. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome. Neuron. 47 (2005) 339-352
-
(2005)
Neuron.
, vol.47
, pp. 339-352
-
-
Koekkoek, S.K.1
-
23
-
-
0035864826
-
Evidence that fragile X mental retardation protein is a negative regulator of translation
-
Laggerbauer B., et al. Evidence that fragile X mental retardation protein is a negative regulator of translation. Hum. Mol. Genet. 10 (2001) 329-338
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 329-338
-
-
Laggerbauer, B.1
-
24
-
-
22044444318
-
Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors
-
Lea P.M.t., et al. Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors. Br. J. Pharmacol. 145 (2005) 527-534
-
(2005)
Br. J. Pharmacol.
, vol.145
, pp. 527-534
-
-
Lea, P.M.t.1
-
25
-
-
6344276563
-
The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development
-
Lu R., et al. The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 15201-15206
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15201-15206
-
-
Lu, R.1
-
26
-
-
0035708355
-
Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons
-
Matsuzaki M., et al. Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nat. Neurosci. 4 (2001) 1086-1092
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 1086-1092
-
-
Matsuzaki, M.1
-
27
-
-
20044388322
-
Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome
-
McBride S.M., et al. Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome. Neuron 45 (2005) 753-764
-
(2005)
Neuron
, vol.45
, pp. 753-764
-
-
McBride, S.M.1
-
28
-
-
33244492432
-
The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo
-
Mientjes E.J., et al. The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo. Neurobiol. Dis. 21 (2006) 549-555
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 549-555
-
-
Mientjes, E.J.1
-
29
-
-
0033515516
-
Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: a preliminary report
-
Miller L.J., et al. Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: a preliminary report. Am. J. Med. Genet. 83 (1999) 268-279
-
(1999)
Am. J. Med. Genet.
, vol.83
, pp. 268-279
-
-
Miller, L.J.1
-
30
-
-
0037421721
-
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice
-
Miyashiro K.Y., et al. RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron 37 (2003) 417-431
-
(2003)
Neuron
, vol.37
, pp. 417-431
-
-
Miyashiro, K.Y.1
-
31
-
-
34249064936
-
Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome
-
Muddashetty R.S., et al. Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. J. Neurosci. 27 (2007) 5338-5348
-
(2007)
J. Neurosci.
, vol.27
, pp. 5338-5348
-
-
Muddashetty, R.S.1
-
32
-
-
0033987591
-
Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome
-
Musumeci S.A., et al. Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome. Epilepsia 41 (2000) 19-23
-
(2000)
Epilepsia
, vol.41
, pp. 19-23
-
-
Musumeci, S.A.1
-
33
-
-
34848890329
-
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors
-
Nakamoto M., et al. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 15537-15542
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 15537-15542
-
-
Nakamoto, M.1
-
34
-
-
0035879180
-
Abnormal development of dendritic spines in fmr1 knock-out mice
-
Nimchinsky E.A., et al. Abnormal development of dendritic spines in fmr1 knock-out mice. J. Neurosci. 21 (2001) 5139-5146
-
(2001)
J. Neurosci.
, vol.21
, pp. 5139-5146
-
-
Nimchinsky, E.A.1
-
35
-
-
10344245542
-
Cadherin activity is required for activity-induced spine remodeling
-
Okamura K., et al. Cadherin activity is required for activity-induced spine remodeling. J. Cell Biol. 167 (2004) 961-972
-
(2004)
J. Cell Biol.
, vol.167
, pp. 961-972
-
-
Okamura, K.1
-
36
-
-
0028860053
-
Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons
-
Papa M., et al. Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons. J. Neurosci. 15 (1995) 1-11
-
(1995)
J. Neurosci.
, vol.15
, pp. 1-11
-
-
Papa, M.1
-
37
-
-
3042522901
-
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre-and post-synaptic mechanisms and lack of direct NMDA blocking activity
-
Popoli P., et al. Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre-and post-synaptic mechanisms and lack of direct NMDA blocking activity. J. Neurochem. 89 (2004) 1479-1489
-
(2004)
J. Neurochem.
, vol.89
, pp. 1479-1489
-
-
Popoli, P.1
-
38
-
-
27144537834
-
Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity
-
Porter R.H., et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J. Pharmacol. Exp. Ther. 315 (2005) 711-721
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 711-721
-
-
Porter, R.H.1
-
39
-
-
0035708880
-
Internalization of ionotropic glutamate receptors in response to mGluR activation
-
Snyder E.M., et al. Internalization of ionotropic glutamate receptors in response to mGluR activation. Nat. Neurosci. 4 (2001) 1079-1085
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 1079-1085
-
-
Snyder, E.M.1
-
40
-
-
33745588863
-
Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins
-
Spencer C.M., et al. Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins. Hum. Mol. Genet. 15 (2006) 1884-1894
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1884-1894
-
-
Spencer, C.M.1
-
41
-
-
38749114229
-
Dynamic association of the fragile X mental retardation protein as an mRNP between microtubules and polyribosomes
-
Wang H., et al. Dynamic association of the fragile X mental retardation protein as an mRNP between microtubules and polyribosomes. Mol. Biol. Cell. 19 1 (2008) 105-114
-
(2008)
Mol. Biol. Cell.
, vol.19
, Issue.1
, pp. 105-114
-
-
Wang, H.1
-
42
-
-
0345528532
-
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
-
Weiler I.J., et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 5395-5400
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 5395-5400
-
-
Weiler, I.J.1
-
43
-
-
10644270727
-
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses
-
Weiler I.J., et al. Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 17504-17509
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 17504-17509
-
-
Weiler, I.J.1
-
44
-
-
24344457816
-
Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP
-
Yan Q.J., et al. Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP. Neuropharmacology. 49 (2005) 1053-1066
-
(2005)
Neuropharmacology.
, vol.49
, pp. 1053-1066
-
-
Yan, Q.J.1
-
45
-
-
34247485947
-
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
-
Zalfa F., et al. A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat. Neurosci. 10 5 (2007) 578-587
-
(2007)
Nat. Neurosci.
, vol.10
, Issue.5
, pp. 578-587
-
-
Zalfa, F.1
-
46
-
-
33846307715
-
Metabotropic glutamate subtype 5 receptors modulate fear-conditioning induced enhancement of prepulse inhibition in rats
-
Zou D., et al. Metabotropic glutamate subtype 5 receptors modulate fear-conditioning induced enhancement of prepulse inhibition in rats. Neuropharmacology. 52 (2007) 476-486
-
(2007)
Neuropharmacology.
, vol.52
, pp. 476-486
-
-
Zou, D.1
|