Peripheral group I metabotropic glutamate receptors modulate nociception in mice

Nature Neuroscience

Volumn 4, Issue 4, 2001, Pages 417-423

  Bhave, G ^a   Karim, F ^a   Carlton, S M ^b   Gereau Iv, R W ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METABOTROPIC RECEPTOR; PHOSPHOLIPASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; INFLAMMATION; MOUSE; NERVE CELL EXCITABILITY; NEUROMODULATION; NOCICEPTION; NONHUMAN; NONMYELINATED NERVE; PAIN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SYNAPTIC TRANSMISSION; THERMAL STIMULATION;

ANIMALS; CHROMONES; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; HEAT; HINDLIMB; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; NEURONS, AFFERENT; PAIN; PAIN MEASUREMENT; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE; VALINE;

EID: 0035094199     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/86075     Document Type: Article

References (42)

1. Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin
2. Ultrastructural analysis of NMDA, AMPA, and kainate receptors on unmyelinated and myelinated axons in the periphery
3. Glutamate participates in the peripheral modulation of thermal hyperalgesia in rats
4. Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats
5. Peripheral NMDA and non-NMDA glutamate receptors contribute to nociceptive behaviors in the rat formalin test
6. Peripheral glutamate release in the hindpaw following low and high intensity sciatic stimulation
7. Formalin-induced release of excitatory amino acids in the skin of the rat hindpaw
8. Excitatory amino acid profiles of synovial fluid from patients with arthritis
9. Pharmacology and functions of metabotropic glutamate receptors
10. Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons
11. Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells
12. Hyperalgesia and allodynia induced by intrathecal (RS)-dihydroxyphenylglycine in rats
13. Comparison of nociceptive effects produced by intrathecal administration of mGluR agonists
14. The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception
15. Intrathecal administration of the mGluR compound (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats
16. Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord
17. Cellular and subcellular localization of the mGluR5a metabotropic glutamate receptor in rat spinal cord
18. Metabotropic glutamate receptor mRNA expression in rat spinal cord
19. mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: A developmental study
20. Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn
21. 2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones
22. Opioid receptors on peripheral sensory axons
23. 3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus
24. Role of specific metabotropic glutamate receptor subtypes in regulating hippocampal CA1 pyramidal cell excitability
25. Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist
26. 2-methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist
27. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding
28. A novel class of antagonists for metabotropic glutamate receptors, 7-(hydroxyimino)cyclopropa[b] chromen-1a-carboxylates
29. (+)-2-methyl-4-carboxyphenylglycine (LY367385) selectively antagonises metabotropic glutamate mGluR1 receptors
30. Direct effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-D-aspartate receptors
31. Formalin induces biphasic activity in C-fibers in the rat
32. Formalin-evoked activity in identified primary afferent fibers: Systemic lidocaine suppresses phase-2 activity
33. Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input
34. Central nervous system plasticity in the tonic pain response to subcutaneous formalin injection
35. The formalin test: An evaluation of the method
36. Electrophysiological assessment of the cutaneous arborization of Adeltafiber nociceptors
37. Evidence for the interaction of glutamate and NK1 receptors in the periphery
38. Amino acid release into the knee joint: Key role in nociception and inflammation
39. mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurons mediate inflammatory hyperaglesia
40. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
41. The formalin test: Scoring properties of the first and second phases of the pain response in rats
42. Glutamate receptors on postganglionic sympathetic axons