Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R,3'R)-2-(2',3'- dicarboxycyclopropyl)glycine (DCG-IV)

Brain Research

Volumn 805, Issue 1-2, 1998, Pages 138-143

  Attwell, P J E ^a,d   Singh Kent, N ^a   Jane, D E ^c   Croucher, M J ^b   Bradford, H F ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c Dept Anat Sch Med Sci U   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

DCG IV; Epileptogenesis; Glutamate release; Group II metabotropic glutamate receptor; Kindling; Lamotrigine; Presynaptic glutamate receptor; Seizure

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 (CARBOXYCYCLOPROPYL)GLYCINE; ASPARTIC ACID; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; LAMOTRIGINE; METABOTROPIC RECEPTOR; SODIUM CHANNEL; VERATRIDINE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN SYNAPTOSOME; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; DRUG POTENCY; EPILEPTOGENESIS; KINDLING; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE SUSCEPTIBILITY; SEIZURE THRESHOLD;

AMYGDALA; ANIMALS; ANTICONVULSANTS; ASPARTIC ACID; CEREBRAL CORTEX; CYCLOPROPANES; GLUTAMIC ACID; GLYCINE; KINDLING, NEUROLOGIC; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SEIZURES; SYNAPTOSOMES; TRIAZINES;

EID: 0032517175     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00698-2     Document Type: Article

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