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Volumn 107, Issue 4, 2004, Pages 365-371

Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease

Author keywords

Alzheimer's disease; Glutamate; Metabotropic glutamate receptor; Neurofibrillary pathology

Indexed keywords

METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE; TAU PROTEIN;

EID: 1842638281     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-004-0820-8     Document Type: Article
Times cited : (60)

References (50)
  • 2
    • 0033537306 scopus 로고    scopus 로고
    • Signal transduction abnormalities in Alzheimer's disease: Evidence of a pathogenic stimuli
    • McShea A, Zelasko DA, Gerst JL, Smith MA (1999) Signal transduction abnormalities in Alzheimer's disease: evidence of a pathogenic stimuli. Brain Res 815:237
    • (1999) Brain Res. , vol.815 , pp. 237
    • McShea, A.1    Zelasko, D.A.2    Gerst, J.L.3    Smith, M.A.4
  • 5
    • 0033004346 scopus 로고    scopus 로고
    • Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors
    • Ferraguti F, Baldani-Guerra B, Corsi M, Nakanishi S, Corti C (1999) Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors. Eur J Neurosci 11:2073
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2073
    • Ferraguti, F.1    Baldani-Guerra, B.2    Corsi, M.3    Nakanishi, S.4    Corti, C.5
  • 7
    • 0031912995 scopus 로고    scopus 로고
    • Glutamate receptors in the mammalian central nervous system
    • Ozawa S, Kamiya H, Tsuzuki K (1998) Glutamate receptors in the mammalian central nervous system. Prog Neurobiol 54:581
    • (1998) Prog. Neurobiol. , vol.54 , pp. 581
    • Ozawa, S.1    Kamiya, H.2    Tsuzuki, K.3
  • 8
    • 0026087014 scopus 로고
    • Ischaemic brain damage - Prevention with competitive and non-competitive antagonists of N-methyl-D-aspartate receptors
    • McCulloch J (1991) Ischaemic brain damage - prevention with competitive and non-competitive antagonists of N-methyl-D-aspartate receptors. Drug Res 41:319
    • (1991) Drug Res. , vol.41 , pp. 319
    • McCulloch, J.1
  • 9
    • 33845212776 scopus 로고    scopus 로고
    • Pharmacology of AMPA antagonists and their role in neuroprotection
    • Gill R, Lodge D (1997) Pharmacology of AMPA antagonists and their role in neuroprotection. Int Rev Neurobiol 40:197
    • (1997) Int. Rev. Neurobiol. , vol.40 , pp. 197
    • Gill, R.1    Lodge, D.2
  • 11
    • 0033057319 scopus 로고    scopus 로고
    • New perspectives for the development of selective metabotropic glutamate receptor ligands
    • Pin JP, De Colle C, Bessis AS, Acher F (1999) New perspectives for the development of selective metabotropic glutamate receptor ligands. Eur J Pharmacol 375:277
    • (1999) Eur. J. Pharmacol. , vol.375 , pp. 277
    • Pin, J.P.1    De Colle, C.2    Bessis, A.S.3    Acher, F.4
  • 12
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin JP, Duvoisin R (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34:1
    • (1995) Neuropharmacology , vol.34 , pp. 1
    • Pin, J.P.1    Duvoisin, R.2
  • 14
    • 0029874694 scopus 로고    scopus 로고
    • The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations
    • Petralia RS, Wang YX, Niedzielski AS, Wenthold RJ (1996) The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience 71:949
    • (1996) Neuroscience , vol.71 , pp. 949
    • Petralia, R.S.1    Wang, Y.X.2    Niedzielski, A.S.3    Wenthold, R.J.4
  • 15
    • 0029156276 scopus 로고
    • The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death
    • Buisson A, Choi DW (1995) The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death. Neuropharmacology 34:1081
    • (1995) Neuropharmacology , vol.34 , pp. 1081
    • Buisson, A.1    Choi, D.W.2
  • 16
    • 0030031001 scopus 로고    scopus 로고
    • DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons
    • Buisson A, Yu SP, Choi DW (1996) DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons. Eur J Neurosci 8:138
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 138
    • Buisson, A.1    Yu, S.P.2    Choi, D.W.3
  • 17
    • 0032791811 scopus 로고    scopus 로고
    • Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795
    • Kingston AE, O'Neill MJ, Lam A, Bales KR, Monn JA, Schoepp DD (1999) Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795. Eur J Pharmacol 377:155
    • (1999) Eur. J. Pharmacol. , vol.377 , pp. 155
    • Kingston, A.E.1    O'Neill, M.J.2    Lam, A.3    Bales, K.R.4    Monn, J.A.5    Schoepp, D.D.6
  • 19
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, Belle G van, Berg L (1991) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41:479
    • (1991) Neurology , vol.41 , pp. 479
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Sumi, S.M.4    Crain, B.J.5    Brownlee, L.M.6    Vogel, F.S.7    Hughes, J.P.8    van Belle, G.9    Berg, L.10
  • 20
    • 0031255112 scopus 로고    scopus 로고
    • Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease
    • Hyman BT, Trojanowski JQ (1997) Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol 56: 1095
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1095
    • Hyman, B.T.1    Trojanowski, J.Q.2
  • 21
    • 0035825371 scopus 로고    scopus 로고
    • Developmental and sensory-dependent changes of group II metabotropic glutamate receptors
    • Reid SN, Romano C (2001) Developmental and sensory-dependent changes of group II metabotropic glutamate receptors. J Comp Neurol 429:270
    • (2001) J. Comp. Neurol. , vol.429 , pp. 270
    • Reid, S.N.1    Romano, C.2
  • 22
    • 0029903640 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 is a disulfide-linked dimer
    • Romano C, Yang WL, O'Malley KL (1996) Metabotropic glutamate receptor 5 is a disulfide-linked dimer. J Biol Chem 271: 28612
    • (1996) J. Biol. Chem. , vol.271 , pp. 28612
    • Romano, C.1    Yang, W.L.2    O'Malley, K.L.3
  • 24
    • 0030583622 scopus 로고    scopus 로고
    • Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus
    • Blumcke I, Behle K, Malitschek B, Kuhn R, Knopfel T, Wolf HK, Wiestler OD (1996) Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus. Brain Res 736: 217
    • (1996) Brain Res. , vol.736 , pp. 217
    • Blumcke, I.1    Behle, K.2    Malitschek, B.3    Kuhn, R.4    Knopfel, T.5    Wolf, H.K.6    Wiestler, O.D.7
  • 25
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239
    • (1991) Acta Neuropathol. , vol.82 , pp. 239
    • Braak, H.1    Braak, E.2
  • 26
    • 0029015501 scopus 로고
    • Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists
    • Couratier P, Sindou P, Tabaraud F, Diop AG, Spencer PS, Hugon J (1995) Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists. Neurodegeneration 4:33
    • (1995) Neurodegeneration , vol.4 , pp. 33
    • Couratier, P.1    Sindou, P.2    Tabaraud, F.3    Diop, A.G.4    Spencer, P.S.5    Hugon, J.6
  • 27
    • 0032101953 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activation in vivo induces intraneuronal amyloid immunoreactivity in guinea pig hippocampus
    • Stephenson DT, Clemens JA (1998) Metabotropic glutamate receptor activation in vivo induces intraneuronal amyloid immunoreactivity in guinea pig hippocampus. Neurochem Int 33: 83
    • (1998) Neurochem. Int. , vol.33 , pp. 83
    • Stephenson, D.T.1    Clemens, J.A.2
  • 28
    • 0033571938 scopus 로고    scopus 로고
    • Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases
    • Otani S, Auclair N, Desce JM, Roisin MP, Crepel F (1999) Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. J Neurosci 19:9788
    • (1999) J. Neurosci. , vol.19 , pp. 9788
    • Otani, S.1    Auclair, N.2    Desce, J.M.3    Roisin, M.P.4    Crepel, F.5
  • 29
    • 0034067992 scopus 로고    scopus 로고
    • Phosphorylation sites on tau identified by nano-electrospray mass spectrometry: Differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta
    • Reynolds CH, Betts JC, Blackstock WP, Nebreda AR, Anderton BH (2000) Phosphorylation sites on tau identified by nano-electrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta. J Neurochem 74:1587
    • (2000) J. Neurochem. , vol.74 , pp. 1587
    • Reynolds, C.H.1    Betts, J.C.2    Blackstock, W.P.3    Nebreda, A.R.4    Anderton, B.H.5
  • 30
    • 0033011390 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury
    • Allen JW, Ivanova SA, Fan L, Espey MG, Basile AS, Faden AI (1999) Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury. J Pharmacol Exp Ther 290: 112
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 112
    • Allen, J.W.1    Ivanova, S.A.2    Fan, L.3    Espey, M.G.4    Basile, A.S.5    Faden, A.I.6
  • 31
    • 0035145543 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP(+)-induced neurotoxicity along with brain-derived neurotrophic factor induction
    • Matarredona ER, Santiago M, Venero JL, Cano J, Machado A (2001) Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP(+)-induced neurotoxicity along with brain-derived neurotrophic factor induction. J Neurochem 76:351
    • (2001) J. Neurochem. , vol.76 , pp. 351
    • Matarredona, E.R.1    Santiago, M.2    Venero, J.L.3    Cano, J.4    Machado, A.5
  • 33
    • 0026647040 scopus 로고
    • Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia
    • Chiamulera C, Albertini P, Valerio E, Reggiani A (1992) Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia. Eur J Pharmacol 216:335
    • (1992) Eur. J. Pharmacol. , vol.216 , pp. 335
    • Chiamulera, C.1    Albertini, P.2    Valerio, E.3    Reggiani, A.4
  • 34
    • 0031028197 scopus 로고    scopus 로고
    • Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat
    • Miyamoto M, Ishida M, Shinozaki H (1997) Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for group II metabotropic glutamate receptors against intraventricular kainate in the rat. Neuroscience 77:131
    • (1997) Neuroscience , vol.77 , pp. 131
    • Miyamoto, M.1    Ishida, M.2    Shinozaki, H.3
  • 35
    • 0032834028 scopus 로고    scopus 로고
    • Pharmacological agents acting at subtypes of metabotropic glutamate receptors
    • Schoepp DD, Jane DE, Monn JA (1999) Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38:1431
    • (1999) Neuropharmacology , vol.38 , pp. 1431
    • Schoepp, D.D.1    Jane, D.E.2    Monn, J.A.3
  • 36
    • 0032403407 scopus 로고    scopus 로고
    • Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta
    • Bruno V, Battaglia G, Casabona G, Copani A, Caciagli F, Nicoletti F (1998) Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. J Neurosci 18:9594
    • (1998) J. Neurosci. , vol.18 , pp. 9594
    • Bruno, V.1    Battaglia, G.2    Casabona, G.3    Copani, A.4    Caciagli, F.5    Nicoletti, F.6
  • 37
    • 0030852182 scopus 로고    scopus 로고
    • In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats
    • Battaglia G, Monn JA, Schoepp DD (1997) In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats. Neurosci Lett 229:161
    • (1997) Neurosci. Lett. , vol.229 , pp. 161
    • Battaglia, G.1    Monn, J.A.2    Schoepp, D.D.3
  • 38
    • 0031757268 scopus 로고    scopus 로고
    • Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV
    • Kilbride J, Huang LQ, Rowan MJ, Anwyl R (1998) Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV. Eur J Pharmacol 356: 149
    • (1998) Eur. J. Pharmacol. , vol.356 , pp. 149
    • Kilbride, J.1    Huang, L.Q.2    Rowan, M.J.3    Anwyl, R.4
  • 40
  • 41
    • 0034938257 scopus 로고    scopus 로고
    • Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease
    • Hynd MR, Scott HL, Dodd PR (2001) Glutamate(NMDA) receptor NR1 subunit mRNA expression in Alzheimer's disease. J Neurochem 78:175
    • (2001) J. Neurochem. , vol.78 , pp. 175
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 42
    • 0035188745 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease
    • Sze C, Bi H, Kleinschmidt-DeMasters BK, Filley CM, Martin LJ (2001) N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease. J Neurol Sci 182:151
    • (2001) J. Neurol. Sci. , vol.182 , pp. 151
    • Sze, C.1    Bi, H.2    Kleinschmidt-DeMasters, B.K.3    Filley, C.M.4    Martin, L.J.5
  • 43
    • 0030930206 scopus 로고    scopus 로고
    • The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains
    • Ikonomovic MD, Mizukami K, Davies P, Hamilton R, Sheffield R, Armstrong DM (1997) The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains. J Neuropathol Exp Neurol 56:1018
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1018
    • Ikonomovic, M.D.1    Mizukami, K.2    Davies, P.3    Hamilton, R.4    Sheffield, R.5    Armstrong, D.M.6
  • 44
    • 0029843713 scopus 로고    scopus 로고
    • AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal dentate gyrus of patients with Alzheimer disease. Evidence for hippocampal plasticity
    • Armstrong DM, Ikonomovic MD (1996) AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal dentate gyrus of patients with Alzheimer disease. Evidence for hippocampal plasticity. Mol Chem Neuropathol 28:59
    • (1996) Mol. Chem. Neuropathol. , vol.28 , pp. 59
    • Armstrong, D.M.1    Ikonomovic, M.D.2
  • 45
    • 0030777850 scopus 로고    scopus 로고
    • Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant
    • Thorns V, Mallory M, Hansen L, Masliah E (1997) Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant. Acta Neuropathol 94:539
    • (1997) Acta Neuropathol. , vol.94 , pp. 539
    • Thorns, V.1    Mallory, M.2    Hansen, L.3    Masliah, E.4
  • 47
    • 0028952094 scopus 로고
    • Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: A biochemical study
    • Yasuda RP, Ikonomovic MD, Sheffield R, Rubin RT, Wolfe BB, Armstrong DM (1995) Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study. Brain Res 678:161
    • (1995) Brain Res. , vol.678 , pp. 161
    • Yasuda, R.P.1    Ikonomovic, M.D.2    Sheffield, R.3    Rubin, R.T.4    Wolfe, B.B.5    Armstrong, D.M.6
  • 48
    • 0035800188 scopus 로고    scopus 로고
    • Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS
    • Laslo P, Lipski J, Funk GD (2001) Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS. Neuroreport 12:1903
    • (2001) Neuroreport , vol.12 , pp. 1903
    • Laslo, P.1    Lipski, J.2    Funk, G.D.3
  • 49
    • 0035881425 scopus 로고    scopus 로고
    • Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: Implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis
    • Tomiyama M, Kimura T, Maeda T, Tanaka H, Furusawa K, Kurahashi K, Matsunaga M (2001) Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis. J Neurol Sci 189:65
    • (2001) J. Neurol. Sci. , vol.189 , pp. 65
    • Tomiyama, M.1    Kimura, T.2    Maeda, T.3    Tanaka, H.4    Furusawa, K.5    Kurahashi, K.6    Matsunaga, M.7
  • 50
    • 0033019102 scopus 로고    scopus 로고
    • The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains
    • Oka A, Takashima S (1999) The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains. Acta Neuropathol 97:275
    • (1999) Acta Neuropathol. , vol.97 , pp. 275
    • Oka, A.1    Takashima, S.2


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