Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test

Neuroscience and Biobehavioral Reviews

Volumn 29, Issue 4-5, 2005, Pages 547-569

  Cryan, John F ^a,c   Valentino, Rita J ^b   Lucki, Irwin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antidepressant; Behavior; Depression; Serotonin

Indexed keywords

2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 2 AMINO 3 (3,4 DICHLOROBENZYLOXY) 6 FLUOROBICYCLO[3.1.0]HEXANE 2,6 DICARBOXYLIC ACID; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; 8 AMINO 7 CHLORO 1,4 BENZODIOXAN 5 CARBOXYLIC ACID 1 BUTYL 4 PIPERIDINYLMETHYL ESTER; ALPRAZOLAM; AMFEBUTAMONE; ANTALARMIN; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; BUSPIRONE; CATECHOLAMINE; CGP 56433A; CITALOPRAM; CLOMIPRAMINE; CORTICOTROPIN RELEASING FACTOR; CYTIDINE; DESIPRAMINE; DULOXETINE; EMD 281014; ESTRADIOL; ETHINYLESTRADIOL; FLUOXETINE; FLUVOXAMINE; GBR 127935; GEPIRONE; IDAZOXAN; IPSAPIRONE; LIDOCAINE; LU 10134C; MAPROTILINE; MCL 0129; METHYLPHENIDATE; MIANSERIN; MILNACIPRAN; MIRTAZAPINE; MOCLOBEMIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NEFAZODONE; NICOTINAMIDE; PAROXETINE; PINDOLOL; R 278995; REBOXETINE; RECEPTOR SUBTYPE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RO 600332; SB 206533; SEROTONIN; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TIANEPTINE; UNCLASSIFIED DRUG; VANOXERINE; VENLAFAXINE; VILAZODONE; WAY 161503;

BEHAVIOR; BEHAVIOR DISORDER; CATECHOLAMINERGIC SYSTEM; CHRONIC DRUG ADMINISTRATION; CLIMBING; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); DEPRESSION; DISEASE MODEL; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; EXPERIMENTAL TEST; FORCED SWIMMING TEST; HUMAN; IMMOBILIZATION; LABORATORY; MEASUREMENT; MEDICAL RESEARCH; METHODOLOGY; MODEL; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; PREDICTION; PRESCRIPTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT STRAIN; REGULATORY MECHANISM; REVIEW; STRAIN DIFFERENCE; STRESS; SWIMMING; SYNAPSE; TASK PERFORMANCE; VALIDATION PROCESS;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; RATS; RECEPTORS, SEROTONIN; SEROTONIN UPTAKE INHIBITORS; SPECIES SPECIFICITY; SWIMMING;

EID: 19944418868     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2005.03.008     Document Type: Review

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