Biology of the cell cycle inhibitor p21CDKN1A: molecular mechanisms and relevance in chemical toxicology

Archives of Toxicology

Volumn 89, Issue 2, 2015, Pages 155-178

  Dutto, Ilaria ^a   Tillhon, Micol ^a   Cazzalini, Ornella ^b   Stivala, Lucia A ^b   Prosperi, Ennio ^a  

^a CNR   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Cell cycle inhibition; Chemical toxicity; DNA damage response; DNA repair; Genotoxic compounds; p21CDKN1A WAF1 CIP1

Indexed keywords

ALUMINUM; ARSENIC; ASBESTOS; BACTERIAL TOXIN; BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA; ENDOCRINE DISRUPTOR; HEAVY METAL; MERCURY; MYCOTOXIN; NANOPARTICLE; ORGANIC COMPOUND; OXYGEN; PESTICIDE; PLANT MEDICINAL PRODUCT; PROTEIN P21; TOXIN; TRACE ELEMENT; CADMIUM;

AIR POLLUTANT; ANIMAL PRODUCT; APOPTOSIS; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL MOTILITY; CELL RENEWAL; CELLULAR DISTRIBUTION; CHEMICAL TOXICITY; DNA DAMAGE; DNA REPAIR; GENETIC TRANSCRIPTION; HUMAN; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; SENESCENCE; SMOKE; STEM CELL; TOXICITY; ANIMAL; CELL AGING; CELL CYCLE; GENETICS; PHYSIOLOGY;

ANIMALS; APOPTOSIS; ARSENIC; CADMIUM; CELL AGING; CELL CYCLE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA REPAIR; HUMANS; MYCOTOXINS; NANOPARTICLES; PESTICIDES; TRANSCRIPTION, GENETIC;

EID: 84922011528     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1430-4     Document Type: Review

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