Rhodium and iridium salts inhibit proliferation and induce DNA damage in rat fibroblasts in vitro

Toxicology in Vitro

Volumn 26, Issue 6, 2012, Pages 963-969

  Iavicoli, Ivo ^a   Cufino, Valerio ^a   Corbi, Maddalena ^a   Goracci, Martina ^a   Caredda, Emanuele ^a   Cittadini, Achille ^a   Bergamaschi, Antonio ^a   Sgambato, Alessandro ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

DNA damage; Platinum group elements; Rat fibroblasts; Toxicity

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; IRIDIUM; IRIDIUM DERIVATIVE; PRB PROTEIN; REACTIVE OXYGEN METABOLITE; RHODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIPLOIDY; DNA DAMAGE; DNA STRAND BREAKAGE; EMBRYO; FIBROBLAST; GROWTH INHIBITION; IN VITRO STUDY; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; FIBROBLASTS; IRIDIUM; RATS; RHODIUM;

RATTUS;

EID: 84863824724     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.03.014     Document Type: Article

References (31)

1. Artelt S., Kock H., König H.P., Levsen K., Rosner G. Engine dynamometer experiments: platinum emissions from differently aged three-way catalytic converters. Atmos. Environ. 1999, 33:3559-3567.
2. Barefoot R.R. Determination of platinum at trace levels in environmental and biological materials. Environ. Sci. Technol. 1997, 31:309-314.
3. Bedello P.G., Goitre M., Roncarolo G., Bundino S., Cane D. Contact dermatitis to rhodium. Contact Dermatitis 1987, 17:111-112.
4. Bergman A., Svedberg U., Nilsson E. Contact urticaria with anaphylactic reactions caused by occupational exposure to iridium salt. Contact Dermatitis 1995, 32:14-17.
5. Botrè C., Tosi M., Mazzei F., Bocca B., Petrucci F., Alimonti A. Automotive catalytic converters and environmental pollution: role of the platinum group elements in the redox reactions and free radicals production. Int. J. Environ. Health 2007, 1:142-152.
6. Brook M.A. Platinum in silicone breast implants. Biomaterials 2006, 27:3274-3286.
7. Bünger J., Stork J., Stalder K. Cyto and genotoxic effects of coordination complexes of platinum, palladium and rhodium in vitro. Int. Arch. Occup. Environ. Health 1996, 69:33-38.
8. Cristaudo A., Sera F., Severino V., De Rocco M., Di Lella E., Picardo M. Occupational hypersensitivity to metal salts, including platinum, in the secondary industry. Allergy 2005, 60:159-164.
9. De la Cuadra J., Grau-Massanés M. Occupational contact dermatitis from rhodium and cobalt. Contact Dermatitis 1991, 25:182-184.
10. De la Fuente E.G., Alvarez J.G., Vicente F.J., Sols M., Naz E., Lopez-Estebaranz J.L. Occupational contact dermatitis caused by rhodium. Am. J. Contact Dermatitis 2003, 14:172-173.
11. Gagnon Z.E., Newkirk C., Hicks S. Impact of platinum group metals on the environment: a toxicological, genotoxic and analytical chemistry study. J. Environ. Sci. Health A Tox Hazard Subst. Environ. Eng. 2006, 41:397-414.
12. Iavicoli I., Bocca B., Carelli G., Caroli S., Caimi S., Alimonti A., Fontana L. Biomonitoring of tram drivers exposed to airborne platinum, rhodium and palladium. Int. Arch. Occup. Environ. Health 2007, 81:109-114.
13. Iavicoli I., Bocca B., Caroli S., Caimi S., Alimonti A., Carelli G., Fontana L. Exposure of Rome city tram drivers to airborne platinum, rhodium, and palladium. J. Occup. Environ. Med. 2008, 50:1158-1166.
14. Iavicoli I., Carelli G., Bocca B., Caimi S., Fontana L., Alimonti A. Environmental and biological monitoring of iridium in the city of Rome. Chemosphere 2008, 71:568-573.
15. Iavicoli I., Fontana L., Marinaccio A., Bergamaschi A., Calabrese E.J. Iridium alters immune balance between T helper 1 and T helper 2 responses. Hum. Exp. Toxicol. 2010, 29:213-219.
16. Landolt R.R., Berk H.W., Russell H.T. Studies on the toxicity of rhodium trichloride in rats and rabbits. Toxicol. Appl. Pharmacol. 1972, 21:589-590.
17. Merget R., Sander I., Van Kampen V., Raulf-Heimsoth M., Ulmer H.M., Kulzer R., Bruening T. Occupational immediate-type asthma and rhinitis due to rhodium salts. Am. J. Ind. Med. 2010, 53:42-46.
18. Migliore L., Frenzilli G., Nesti C., Fortaner S., Sabbioni E. Cytogenetic and oxidative damage induced in human lymphocytes by platinum, rhodium and palladium compounds. Mutagenesis 2002, 17:411-417.
19. Murdoch R.D., Pepys J., Hughes E.G. IgE antibody responses to platinum group metals: a large scale refinery survey. Br. J. Ind. Med. 1986, 43:37-43.
20. Murdoch R.D., Pepys J. Platinum group metal sensitivity: reactivity to platinum group metal salts in platinum halide saltsensitive workers. Ann. Allergy 1987, 59:464-469.
21. Onovwiona H.I., Ugursal V.I. Residential cogeneration systems: review of the current technology. Renew. Sustain Energy Rev. 2006, 10:389-431.
22. Pyrzyñska K. Recent advances in solid-phase extraction of platinum and palladium. Talanta 1998, 47:841-848.
23. Ravindra K., Bencs L., Van Grieken R. Platinum group elements in the environment and their health risk. Sci. Total Environ. 2004, 318:1-43.
24. Resano M., Garcia-Ruiz E., Belarra M.A., Vanhaecke F., McIntosh K.S. Solid sampling in the determination of precious metals at ultratrace levels. Trends. Anal. Chem. 2007, 26:385-395.
25. Santucci B., Valenzano C., De Rocco M., Cristaudo A. Platinum in the environment: frequency of reactions to platinum-group elements in patients with dermatitis and urticaria. Contact Dermatitis 2000, 43:333-338.
26. Sgambato A., Ardito R., Faraglia B., Boninsegna A., Wolf F.I., Cittadini A. Resveratrol, a natural phenolic compound, inhibits cell proliferation and prevents oxidative DNA damage. Mutat. Res. 2001, 496:171-180.
27. Sgambato A., Iavicoli I., Goracci M., Corbi M., Boninsegna A., Pietroiusti A., Cittadini A., Bergamaschi A. Evaluation of in vitro toxic effects of cement dusts: a preliminary study. Toxicol. Ind. Health. 2010, 26:309-317.
28. Sheard C. Contact dermatitis from platinum and related metals. AMA Arch. Derm. 1955, 71:357-360.
29. Schmid M., Zimmermann S., Krug H.F., Sures B. Influence of platinum, palladium and rhodium as compared with cadmium, nickel and chromium on cell viability and oxidative stress in human bronchial epithelial cells. Environ. Int. 2007, 33:385-390.
30. Twigg M.V. Progress and future challenges in controlling automotive exhaust gas emissions. Appl. Catal B: Environ. 2007, 70:2-15.
31. Zimmermann S., Alt F., Messerschmidt J., von Bohlen A., Taraschewski H., Sures B. Biological availability of traffic related platinum group elements (Pd, Pt, Rh) and other metals to the zebra mussel (Dreissena polymorpha) in water containing road dust. Environ. Toxicol. Chem. 2002, 21:2713-2718.