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Volumn 12, Issue 7, 2013, Pages 1030-1041

Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21Cip1

Author keywords

Aurora kinase B; Cancer target; Mitosis; Spindle assembly checkpoint

Indexed keywords

AURORA B KINASE; CYCLIN B1; CYCLIN DEPENDENT KINASE INHIBITOR 1;

EID: 84875895893     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24004     Document Type: Article
Times cited : (28)

References (63)
  • 1
    • 79960088065 scopus 로고    scopus 로고
    • Physiological relevance of cell cycle kinases
    • PMID:21742793
    • Malumbres M. Physiological relevance of cell cycle kinases. Physiol Rev 2011; 91:973-1007; PMID:21742793; http://dx.doi.org/10.1152/physrev. 00025.2010
    • (2011) Physiol Rev , vol.91 , pp. 973-1007
    • Malumbres, M.1
  • 2
    • 0028938482 scopus 로고
    • Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles
    • PMID:7720077
    • Glover DM, Leibowitz MH, McLean DA, Parry H. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 1995; 81:95-105; PMID:7720077; http://dx.doi. org/10.1016/0092-8674(95)90374-7
    • (1995) Cell , vol.81 , pp. 95-105
    • Glover, D.M.1    Leibowitz, M.H.2    McLean, D.A.3    Parry, H.4
  • 3
    • 0035235736 scopus 로고    scopus 로고
    • Mitotic kinases as regulators of cell division and its checkpoints
    • PMID:11413462
    • Nigg EA. Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol 2001; 2:21-32; PMID:11413462; http://dx.doi. org/10.1038/35048096
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 21-32
    • Nigg, E.A.1
  • 4
    • 0242551545 scopus 로고    scopus 로고
    • The cellular geography of aurora kinases
    • PMID:14625535
    • Carmena M, Earnshaw WC. The cellular geography of aurora kinases. Nat Rev Mol Cell Biol 2003; 4:842- 54; PMID:14625535; http://dx.doi.org/10.1038/nrm1245
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 842-854
    • Carmena, M.1    Earnshaw, W.C.2
  • 5
    • 78649476052 scopus 로고    scopus 로고
    • Shared and separate functions of polo-like kinases and aurora kinases in cancer
    • PMID:21102634
    • Lens SM, Voest EE, Medema RH. Shared and separate functions of polo-like kinases and aurora kinases in cancer. Nat Rev Cancer 2010; 10:825-41; PMID:21102634; http://dx.doi.org/10.1038/nrc2964
    • (2010) Nat Rev Cancer , vol.10 , pp. 825-841
    • Lens, S.M.1    Voest, E.E.2    Medema, R.H.3
  • 6
    • 8744283817 scopus 로고    scopus 로고
    • Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs
    • PMID:15476560
    • Brown JR, Koretke KK, Birkeland ML, Sanseau P, Patrick DR. Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs. BMC Evol Biol 2004; 4:39; PMID:15476560; http://dx.doi. org/10.1186/1471-2148-4-39
    • (2004) BMC Evol Biol , vol.4 , pp. 39
    • Brown, J.R.1    Koretke, K.K.2    Birkeland, M.L.3    Sanseau, P.4    Patrick, D.R.5
  • 7
    • 42049110752 scopus 로고    scopus 로고
    • Aurora-C and Aurora-B share phosphorylation and regulation of CENP-A and Borealin during mitosis
    • PMID:18239465
    • Slattery SD, Moore RV, Brinkley BR, Hall RM. Aurora-C and Aurora-B share phosphorylation and regulation of CENP-A and Borealin during mitosis. Cell Cycle 2008; 7:787-95; PMID:18239465; http://dx.doi.org/10.4161/cc.7.6.5563
    • (2008) Cell Cycle , vol.7 , pp. 787-795
    • Slattery, S.D.1    Moore, R.V.2    Brinkley, B.R.3    Hall, R.M.4
  • 8
    • 79958098477 scopus 로고    scopus 로고
    • Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development
    • PMID:21613325
    • Fernández-Miranda G, Trakala M, Martín J, Escobar B, González A, Ghyselinck NB, et al. Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development. Development 2011; 138:2661-72; PMID:21613325; http://dx.doi. org/10.1242/dev.066381
    • (2011) Development , vol.138 , pp. 2661-2672
    • Fernández-Miranda, G.1    Trakala, M.2    Martín, J.3    Escobar, B.4    González, A.5    Ghyselinck, N.B.6
  • 9
    • 34648825331 scopus 로고    scopus 로고
    • Chromosomal passengers: Conducting cell division
    • PMID:17848966
    • Ruchaud S, Carmena M, Earnshaw WC. Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol 2007; 8:798-812; PMID:17848966; http://dx.doi.org/10.1038/nrm2257
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 798-812
    • Ruchaud, S.1    Carmena, M.2    Earnshaw, W.C.3
  • 10
    • 84870192369 scopus 로고    scopus 로고
    • The chromosomal passenger complex (CPC): From easy rider to the godfather of mitosis
    • PMID:23175282
    • Carmena M, Wheelock M, Funabiki H, Earnshaw WC. The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol 2012; 13:789-803; PMID:23175282; http://dx.doi.org/10.1038/nrm3474
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 789-803
    • Carmena, M.1    Wheelock, M.2    Funabiki, H.3    Earnshaw, W.C.4
  • 11
    • 2342528439 scopus 로고    scopus 로고
    • The survivin/Aurora B complex: Its role in coordinating tension and attachment
    • PMID:14504461
    • Lens SM, Medema RH. The survivin/Aurora B complex: its role in coordinating tension and attachment. Cell Cycle 2003; 2:507-10; PMID:14504461; http://dx.doi.org/10.4161/cc.2.6.559
    • (2003) Cell Cycle , vol.2 , pp. 507-510
    • Lens, S.M.1    Medema, R.H.2
  • 12
    • 34548248276 scopus 로고    scopus 로고
    • Detection and correction of merotelic kinetochore orientation by Aurora B and its partners
    • PMID:17603301
    • Cimini D. Detection and correction of merotelic kinetochore orientation by Aurora B and its partners. Cell Cycle 2007; 6:1558-64; PMID:17603301; http://dx.doi.org/10.4161/cc.6.13.4452
    • (2007) Cell Cycle , vol.6 , pp. 1558-1564
    • Cimini, D.1
  • 13
    • 62149111407 scopus 로고    scopus 로고
    • Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates
    • PMID:19150808
    • Liu D, Vader G, Vromans MJ, Lampson MA, Lens SM. Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science 2009; 323:1350-3; PMID:19150808; http://dx.doi.org/10.1126/ science.1167000
    • (2009) Science , vol.323 , pp. 1350-1353
    • Liu, D.1    Vader, G.2    Vromans, M.J.3    Lampson, M.A.4    Lens, S.M.5
  • 14
    • 18044371706 scopus 로고    scopus 로고
    • Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis
    • PMID:15854913
    • Guse A, Mishima M, Glotzer M. Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis. Curr Biol 2005; 15:778-86; PMID:15854913; http://dx.doi.org/10.1016/j. cub.2005.03.041
    • (2005) Curr Biol , vol.15 , pp. 778-786
    • Guse, A.1    Mishima, M.2    Glotzer, M.3
  • 15
    • 59049101302 scopus 로고    scopus 로고
    • Aurora B-mediated abscission checkpoint protects against tetraploidization
    • PMID:19203582
    • Steigemann P, Wurzenberger C, Schmitz MH, Held M, Guizetti J, Maar S, et al. Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell 2009; 136:473-84; PMID:19203582; http://dx.doi. org/10.1016/j.cell.2008.12. 020
    • (2009) Cell , vol.136 , pp. 473-484
    • Steigemann, P.1    Wurzenberger, C.2    Schmitz, M.H.3    Held, M.4    Guizetti, J.5    Maar, S.6
  • 16
    • 33847001284 scopus 로고    scopus 로고
    • The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes
    • PMID:17128276
    • Song J, Salek-Ardakani S, So T, Croft M. The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes. Nat Immunol 2007; 8:64-73; PMID:17128276; http://dx.doi.org/10.1038/ni1413
    • (2007) Nat Immunol , vol.8 , pp. 64-73
    • Song, J.1    Salek-Ardakani, S.2    So, T.3    Croft, M.4
  • 17
    • 36249031604 scopus 로고    scopus 로고
    • A novel role for the Aurora B kinase in epigenetic marking of silent chromatin in differentiated postmitotic cells
    • PMID:17948062
    • Sabbattini P, Canzonetta C, Sjoberg M, Nikic S, Georgiou A, Kemball-Cook G, et al. A novel role for the Aurora B kinase in epigenetic marking of silent chromatin in differentiated postmitotic cells. EMBO J 2007; 26:4657-69; PMID:17948062; http://dx.doi. org/10.1038/sj.emboj.7601875
    • (2007) EMBO J , vol.26 , pp. 4657-4669
    • Sabbattini, P.1    Canzonetta, C.2    Sjoberg, M.3    Nikic, S.4    Georgiou, A.5    Kemball-Cook, G.6
  • 18
    • 78751502684 scopus 로고    scopus 로고
    • Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression
    • PMID:20959462
    • Wu L, Ma CA, Zhao Y, Jain A. Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression. J Biol Chem 2011; 286:2236- 44; PMID:20959462; http://dx.doi.org/ 10.1074/jbc. M110.174755
    • (2011) J Biol Chem , vol.286 , pp. 2236-2244
    • Wu, L.1    Ma, C.A.2    Zhao, Y.3    Jain, A.4
  • 20
    • 65249093721 scopus 로고    scopus 로고
    • Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780
    • PMID:19225156
    • Nair JS, Ho AL, Tse AN, Coward J, Cheema H, Ambrosini G, et al. Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780. Mol Biol Cell 2009; 20:2218-28; PMID:19225156; http://dx.doi.org/10.1091/mbc.E08-08-0885
    • (2009) Mol Biol Cell , vol.20 , pp. 2218-2228
    • Nair, J.S.1    Ho, A.L.2    Tse, A.N.3    Coward, J.4    Cheema, H.5    Ambrosini, G.6
  • 21
    • 0013057087 scopus 로고    scopus 로고
    • Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
    • PMID:12719470
    • Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, et al. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 2003; 161:267-80; PMID:12719470; http://dx.doi. org/10.1083/jcb.200208091
    • (2003) J Cell Biol , vol.161 , pp. 267-280
    • Ditchfield, C.1    Johnson, V.L.2    Tighe, A.3    Ellston, R.4    Haworth, C.5    Johnson, T.6
  • 22
    • 0038746733 scopus 로고    scopus 로고
    • The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochoremicrotubule attachment and in maintaining the spindle assembly checkpoint
    • PMID:12707311
    • Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochoremicrotubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol 2003; 161:281- 94; PMID:12707311; http://dx.doi.org/10. 1083/jcb.200208092
    • (2003) J Cell Biol , vol.161 , pp. 281-294
    • Hauf, S.1    Cole, R.W.2    Laterra, S.3    Zimmer, C.4    Schnapp, G.5    Walter, R.6
  • 23
    • 35848971221 scopus 로고    scopus 로고
    • The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions
    • PMID:17699588
    • Vader G, Cruijsen CW, van Harn T, Vromans MJ, Medema RH, Lens SM. The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions. Mol Biol Cell 2007; 18:4553- 64; PMID:17699588; http://dx.doi.org/10.1091/mbc. E07-04-0328
    • (2007) Mol Biol Cell , vol.18 , pp. 4553-4564
    • Vader, G.1    Cruijsen, C.W.2    Van Harn, T.3    Vromans, M.J.4    Medema, R.H.5    Lens, S.M.6
  • 24
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: A machine designed to destroy
    • PMID:16896351
    • Peters JM. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 2006; 7:644-56; PMID:16896351; http://dx.doi. org/10.1038/nrm1988
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 644-656
    • Peters, J.M.1
  • 25
    • 78650004841 scopus 로고    scopus 로고
    • Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase
    • PMID:21156286
    • Manchado E, Guillamot M, de Cárcer G, Eguren M, Trickey M, García-Higuera I, et al. Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase. Cancer Cell 2010; 18:641-54; PMID:21156286; http://dx.doi.org/10. 1016/j.ccr.2010.10.028
    • (2010) Cancer Cell , vol.18 , pp. 641-654
    • Manchado, E.1    Guillamot, M.2    De Cárcer, G.3    Eguren, M.4    Trickey, M.5    García-Higuera, I.6
  • 26
    • 0033574614 scopus 로고    scopus 로고
    • Mechanisms of cyclin-dependent kinase regulation: Structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
    • PMID:10222191
    • Pavletich NP. Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J Mol Biol 1999; 287:821-8; PMID:10222191; http://dx.doi. org/10.1006/jmbi.1999.2640
    • (1999) J Mol Biol , vol.287 , pp. 821-828
    • Pavletich, N.P.1
  • 27
    • 25444493567 scopus 로고    scopus 로고
    • Destruction box-dependent degradation of aurora B is mediated by the anaphasepromoting complex/cyclosome and Cdh1
    • PMID:16204042
    • Stewart S, Fang G. Destruction box-dependent degradation of aurora B is mediated by the anaphasepromoting complex/cyclosome and Cdh1. Cancer Res 2005; 65:8730-5; PMID:16204042; http://dx.doi. org/10.1158/0008-5472.CAN-05-1500
    • (2005) Cancer Res , vol.65 , pp. 8730-8735
    • Stewart, S.1    Fang, G.2
  • 28
    • 4444247138 scopus 로고    scopus 로고
    • Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
    • PMID:15315761
    • Malumbres M, Sotillo R, Santamaría D, Galán J, Cerezo A, Ortega S, et al. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 2004; 118:493-504; PMID:15315761; http://dx.doi.org/10.1016/j.cell.2004.08.002
    • (2004) Cell , vol.118 , pp. 493-504
    • Malumbres, M.1    Sotillo, R.2    Santamaría, D.3    Galán, J.4    Cerezo, A.5    Ortega, S.6
  • 30
    • 84869391341 scopus 로고    scopus 로고
    • Ser2481-autophosphorylated mTOR colocalizes with chromosomal passenger proteins during mammalian cell cytokinesis
    • PMID:23095638
    • Vazquez-Martin A, Sauri-Nadal T, Menendez OJ, Oliveras-Ferraros C, Cufí S, Corominas-Faja B, et al. Ser2481-autophosphorylated mTOR colocalizes with chromosomal passenger proteins during mammalian cell cytokinesis. Cell Cycle 2012; 11:4211-21; PMID:23095638; http://dx.doi.org/10. 4161/cc.22551
    • (2012) Cell Cycle , vol.11 , pp. 4211-4221
    • Vazquez-Martin, A.1    Sauri-Nadal, T.2    Menendez, O.J.3    Oliveras-Ferraros, C.4    Cufí, S.5    Corominas-Faja, B.6
  • 31
    • 0034594915 scopus 로고    scopus 로고
    • Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death
    • PMID:10713676
    • Suzuki A, Ito T, Kawano H, Hayashida M, Hayasaki Y, Tsutomi Y, et al. Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death. Oncogene 2000; 19:1346-53; PMID:10713676; http://dx.doi. org/10.1038/sj.onc.1203429
    • (2000) Oncogene , vol.19 , pp. 1346-1353
    • Suzuki, A.1    Ito, T.2    Kawano, H.3    Hayashida, M.4    Hayasaki, Y.5    Tsutomi, Y.6
  • 32
    • 79551534879 scopus 로고    scopus 로고
    • When Aurora B met p53: Newly revealed regulatory phosphorylation in an old protein
    • PMID:21212738
    • Wu L, Ma CA, Jain A. When Aurora B met p53: newly revealed regulatory phosphorylation in an old protein. Cell Cycle 2011; 10:171-2; PMID:21212738; http://dx.doi.org/10.4161/cc.10.2.14349
    • (2011) Cell Cycle , vol.10 , pp. 171-172
    • Wu, L.1    Ma, C.A.2    Jain, A.3
  • 34
    • 84869470926 scopus 로고    scopus 로고
    • FBW7-Aurora B-p53 feedback loop regulates mitosis and cell growth
    • PMID:23099923
    • Wang Y, Zhou BP. FBW7-Aurora B-p53 feedback loop regulates mitosis and cell growth. Cell Cycle 2012; 11:4113-4; PMID:23099923; http://dx.doi. org/10.4161/cc.22607
    • (2012) Cell Cycle , vol.11 , pp. 4113-4114
    • Wang, Y.1    Zhou, B.P.2
  • 35
    • 84866749750 scopus 로고    scopus 로고
    • P53 negatively regulates Aurora A via both transcriptional and posttranslational regulation
    • PMID:22894933
    • Wu CC, Yang TY, Yu CT, Phan L, Ivan C, Sood AK, et al. p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle 2012; 11:3433-42; PMID:22894933; http://dx.doi. org/10.4161/cc.21732
    • (2012) Cell Cycle , vol.11 , pp. 3433-3442
    • Wu, C.C.1    Yang, T.Y.2    Yu, C.T.3    Phan, L.4    Ivan, C.5    Sood, A.K.6
  • 36
    • 84868018757 scopus 로고    scopus 로고
    • P53-Aurora A mitotic feedback loop regulates cell cycle progression and genomic stability
    • PMID:22982999
    • Chiang CM. p53-Aurora A mitotic feedback loop regulates cell cycle progression and genomic stability. Cell Cycle 2012; 11:3719-20; PMID:22982999; http://dx.doi.org/10.4161/cc.22113
    • (2012) Cell Cycle , vol.11 , pp. 3719-3720
    • Chiang, C.M.1
  • 37
    • 84857466069 scopus 로고    scopus 로고
    • The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent
    • PMID:22293494
    • Nair JS, Ho AL, Schwartz GK. The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent. Cell Cycle 2012; 11:807- 17; PMID:22293494; http://dx.doi.org/10.4161/cc.11.4.19323
    • (2012) Cell Cycle , vol.11 , pp. 807-817
    • Nair, J.S.1    Ho, A.L.2    Schwartz, G.K.3
  • 38
    • 84872004359 scopus 로고    scopus 로고
    • A novel Aurora-A-mediated phosphorylation of p53 inhibits its interaction with MDM2
    • PMID: 23201157
    • Hsueh KW, Fu SL, Chang CB, Chang YL, Lin CH. A novel Aurora-A-mediated phosphorylation of p53 inhibits its interaction with MDM2. Biochim Biophys Acta 2013; 1834:508-15; PMID:23201157
    • (2013) Biochim Biophys Acta , vol.1834 , pp. 508-515
    • Hsueh, K.W.1    Fu, S.L.2    Chang, C.B.3    Chang, Y.L.4    Lin, C.H.5
  • 39
    • 79952628810 scopus 로고    scopus 로고
    • Functional significance of Aurora kinase A regulatory interactions with p53-ERα complex in human breast cancer cells
    • PMID:21761334
    • Katayama H, Sen S. Functional significance of Aurora kinase A regulatory interactions with p53-ERα complex in human breast cancer cells. Horm Cancer 2011; 2:117-24; PMID:21761334; http://dx.doi. org/10.1007/s12672-011- 0070-x
    • (2011) Horm Cancer , vol.2 , pp. 117-124
    • Katayama, H.1    Sen, S.2
  • 40
    • 6344221309 scopus 로고    scopus 로고
    • Cell division and cell survival in the absence of survivin
    • PMID:15477601
    • Yang D, Welm A, Bishop JM. Cell division and cell survival in the absence of survivin. Proc Natl Acad Sci USA 2004; 101:15100-5; PMID:15477601; http://dx.doi.org/10.1073/pnas.0406665101
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15100-15105
    • Yang, D.1    Welm, A.2    Bishop, J.M.3
  • 41
    • 10744219638 scopus 로고    scopus 로고
    • Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
    • PMID:14757745
    • Okada H, Bakal C, Shahinian A, Elia A, Wakeham A, Suh WK, et al. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. J Exp Med 2004; 199:399-410; PMID:14757745; http://dx.doi.org/10.1084/ jem.20032092
    • (2004) J Exp Med , vol.199 , pp. 399-410
    • Okada, H.1    Bakal, C.2    Shahinian, A.3    Elia, A.4    Wakeham, A.5    Suh, W.K.6
  • 42
    • 35848948611 scopus 로고    scopus 로고
    • Aurora B kinase activity is required to prevent polar cortical ingression during cytokinesis
    • PMID:17726378
    • Miyauchi K, Zhu X, Foong C, Hosoya H, Murata- Hori M. Aurora B kinase activity is required to prevent polar cortical ingression during cytokinesis. Cell Cycle 2007; 6:2549-53; PMID:17726378; http://dx.doi. org/10.4161/cc.6.20. 4817
    • (2007) Cell Cycle , vol.6 , pp. 2549-2553
    • Miyauchi, K.1    Zhu, X.2    Foong, C.3    Hosoya, H.4    Murata- Hori, M.5
  • 43
    • 70549107618 scopus 로고    scopus 로고
    • Sister chromatid tension and the spindle assembly checkpoint
    • PMID:19846287
    • Nezi L, Musacchio A. Sister chromatid tension and the spindle assembly checkpoint. Curr Opin Cell Biol 2009; 21:785-95; PMID:19846287; http://dx.doi. org/10.1016/j.ceb.2009.09.007
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 785-795
    • Nezi, L.1    Musacchio, A.2
  • 44
    • 79954999102 scopus 로고    scopus 로고
    • Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction
    • PMID:21407176
    • Santaguida S, Vernieri C, Villa F, Ciliberto A, Musacchio A. Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. EMBO J 2011; 30:1508-19; PMID:21407176; http://dx.doi.org/10. 1038/emboj.2011.70
    • (2011) EMBO J , vol.30 , pp. 1508-1519
    • Santaguida, S.1    Vernieri, C.2    Villa, F.3    Ciliberto, A.4    Musacchio, A.5
  • 45
    • 33744996707 scopus 로고    scopus 로고
    • Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    • PMID:16782009
    • Brito DA, Rieder CL. Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr Biol 2006; 16:1194- 200; PMID:16782009; http://dx.doi.org/10.1016/j. cub.2006.04.043
    • (2006) Curr Biol , vol.16 , pp. 1194-1200
    • Brito, D.A.1    Rieder, C.L.2
  • 46
    • 77953594908 scopus 로고    scopus 로고
    • Substrate degradation by the anaphase promoting complex occurs during mitotic slippage
    • PMID:20436289
    • Lee J, Kim JA, Margolis RL, Fotedar R. Substrate degradation by the anaphase promoting complex occurs during mitotic slippage. Cell Cycle 2010; 9:1792- 801; PMID:20436289; http://dx.doi.org/10.4161/cc.9.9.11519
    • (2010) Cell Cycle , vol.9 , pp. 1792-1801
    • Lee, J.1    Kim, J.A.2    Margolis, R.L.3    Fotedar, R.4
  • 47
    • 0042025008 scopus 로고    scopus 로고
    • Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts
    • PMID:12881433
    • Baus F, Gire V, Fisher D, Piette J, Dulić V. Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts. EMBO J 2003; 22:3992-4002; PMID:12881433; http://dx.doi.org/10.1093/emboj/cdg387
    • (2003) EMBO J , vol.22 , pp. 3992-4002
    • Baus, F.1    Gire, V.2    Fisher, D.3    Piette, J.4    Dulić, V.5
  • 48
    • 4344574113 scopus 로고    scopus 로고
    • P21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress
    • PMID:15181148
    • Charrier-Savournin FB, Château MT, Gire V, Sedivy J, Piette J, Dulic V. p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress. Mol Biol Cell 2004; 15:3965-76; PMID:15181148; http://dx.doi.org/10.1091/mbc.E03-12-0871
    • (2004) Mol Biol Cell , vol.15 , pp. 3965-3976
    • Charrier-Savournin, F.B.1    Château, M.T.2    Gire, V.3    Sedivy, J.4    Piette, J.5    Dulic, V.6
  • 49
    • 80054029091 scopus 로고    scopus 로고
    • The causes and consequences of polyploidy in normal development and cancer
    • PMID:21801013
    • Davoli T, de Lange T. The causes and consequences of polyploidy in normal development and cancer. Annu Rev Cell Dev Biol 2011; 27:585-610; PMID:21801013; http://dx.doi.org/10.1146/annurevcellbio- 092910-154234
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 585-610
    • Davoli, T.1    De Lange, T.2
  • 50
    • 10344236486 scopus 로고    scopus 로고
    • Aurora-kinase inhibitors as anticancer agents
    • PMID:15573114
    • Keen N, Taylor S. Aurora-kinase inhibitors as anticancer agents. Nat Rev Cancer 2004; 4:927-36; PMID:15573114; http://dx.doi.org/10.1038/nrc1502
    • (2004) Nat Rev Cancer , vol.4 , pp. 927-936
    • Keen, N.1    Taylor, S.2
  • 51
    • 51449108571 scopus 로고    scopus 로고
    • Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
    • PMID:18644252
    • Pérez de Castro I, de Cárcer G, Montoya G, Malumbres M. Emerging cancer therapeutic opportunities by inhibiting mitotic kinases. Curr Opin Pharmacol 2008; 8:375-83; PMID:18644252; http://dx.doi.org/10.1016/j.coph. 2008.06.013
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 375-383
    • Pérez De Castro, I.1    De Cárcer, G.2    Montoya, G.3    Malumbres, M.4
  • 52
    • 18044391525 scopus 로고    scopus 로고
    • Aurora kinases, aneuploidy and cancer, a coincidence or a real link?
    • PMID:15866028
    • Giet R, Petretti C, Prigent C. Aurora kinases, aneuploidy and cancer, a coincidence or a real link? Trends Cell Biol 2005; 15:241-50; PMID:15866028; http://dx.doi.org/10.1016/j.tcb.2005.03.004
    • (2005) Trends Cell Biol , vol.15 , pp. 241-250
    • Giet, R.1    Petretti, C.2    Prigent, C.3
  • 53
  • 54
    • 44949157910 scopus 로고    scopus 로고
    • Molecular basis of drug resistance in aurora kinases
    • PMID:18559266
    • Girdler F, Sessa F, Patercoli S, Villa F, Musacchio A, Taylor S. Molecular basis of drug resistance in aurora kinases. Chem Biol 2008; 15:552-62;. PMID:18559266; http://dx.doi.org/10.1016/j.chembiol. 2008.04.013
    • (2008) Chem Biol , vol.15 , pp. 552-562
    • Girdler, F.1    Sessa, F.2    Patercoli, S.3    Villa, F.4    Musacchio, A.5    Taylor, S.6
  • 55
    • 67649345473 scopus 로고    scopus 로고
    • Aurora B kinase inhibition in mitosis: Strategies for optimising the use of aurora kinase inhibitors such as AT9283
    • PMID:19440047
    • Curry J, Angove H, Fazal L, Lyons J, Reule M, Thompson N, et al. Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283. Cell Cycle 2009; 8:1921-9; PMID:19440047; http://dx.doi. org/10.4161/cc.8.12.8741
    • (2009) Cell Cycle , vol.8 , pp. 1921-1929
    • Curry, J.1    Angove, H.2    Fazal, L.3    Lyons, J.4    Reule, M.5    Thompson, N.6
  • 56
    • 84863787422 scopus 로고    scopus 로고
    • Tetraploidization increases sensitivity to Aurora B kinase inhibition
    • PMID:22722494
    • Marxer M, Foucar CE, Man WY, Chen Y, Ma HT, Poon RY. Tetraploidization increases sensitivity to Aurora B kinase inhibition. Cell Cycle 2012; 11:2567- 77; PMID:22722494; http://dx.doi.org/10.4161/cc.20947
    • (2012) Cell Cycle , vol.11 , pp. 2567-2577
    • Marxer, M.1    Foucar, C.E.2    Man, W.Y.3    Chen, Y.4    Ma, H.T.5    Poon, R.Y.6
  • 57
    • 79956035239 scopus 로고    scopus 로고
    • Evaluation of an Actinomycin D/VX-680 aurora kinase inhibitor combination in p53-based cyclotherapy
    • PMID: 21317459
    • Rao B, van Leeuwen IM, Higgins M, Campbel J, Thompson AM, Lane DP, et al. Evaluation of an Actinomycin D/VX-680 aurora kinase inhibitor combination in p53-based cyclotherapy. Oncotarget 2010; 1:639-50; PMID:21317459
    • (2010) Oncotarget , vol.1 , pp. 639-650
    • Rao, B.1    Van Leeuwen, I.M.2    Higgins, M.3    Campbel, J.4    Thompson, A.M.5    Lane, D.P.6
  • 58
    • 0029097759 scopus 로고
    • Radiation-induced cell cycle arrest compromised by p21 deficiency
    • PMID:7566157
    • Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 1995; 377:552-7; PMID:7566157; http://dx.doi. org/10.1038/377552a0
    • (1995) Nature , vol.377 , pp. 552-557
    • Brugarolas, J.1    Chandrasekaran, C.2    Gordon, J.I.3    Beach, D.4    Jacks, T.5    Hannon, G.J.6
  • 59
    • 46449095540 scopus 로고    scopus 로고
    • Genomic stability and tumour suppression by the APC/C cofactor Cdh1
    • PMID:18552834
    • García-Higuera I, Manchado E, Dubus P, Cañamero M, Méndez J, Moreno S, et al. Genomic stability and tumour suppression by the APC/C cofactor Cdh1. Nat Cell Biol 2008; 10:802-11; PMID:18552834; http://dx.doi.org/10.1038/ncb1742
    • (2008) Nat Cell Biol , vol.10 , pp. 802-811
    • García-Higuera, I.1    Manchado, E.2    Dubus, P.3    Cañamero, M.4    Méndez, J.5    Moreno, S.6
  • 60
    • 34250664283 scopus 로고    scopus 로고
    • Design and cloning of lentiviral vectors expressing small interfering RNAs
    • PMID:17406238
    • Tiscornia G, Singer O, Verma IM. Design and cloning of lentiviral vectors expressing small interfering RNAs. Nat Protoc 2006; 1:234-40; PMID:17406238; http://dx.doi.org/10.1038/nprot.2006.36
    • (2006) Nat Protoc , vol.1 , pp. 234-240
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 61
    • 69949182313 scopus 로고    scopus 로고
    • Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments
    • PMID:19720871
    • Yang Z, Kenny AE, Brito DA, Rieder CL. Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments. J Cell Biol 2009; 186:675-84; PMID:19720871; http://dx.doi.org/10. 1083/jcb.200906150
    • (2009) J Cell Biol , vol.186 , pp. 675-684
    • Yang, Z.1    Kenny, A.E.2    Brito, D.A.3    Rieder, C.L.4
  • 62
    • 3042761646 scopus 로고    scopus 로고
    • BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
    • PMID:15208629
    • Baker DJ, Jeganathan KB, Cameron JD, Thompson M, Juneja S, Kopecka A, et al. BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet 2004; 36:744-9; PMID:15208629; http://dx.doi.org/10.1038/ng1382
    • (2004) Nat Genet , vol.36 , pp. 744-749
    • Baker, D.J.1    Jeganathan, K.B.2    Cameron, J.D.3    Thompson, M.4    Juneja, S.5    Kopecka, A.6
  • 63
    • 50249150340 scopus 로고    scopus 로고
    • A reproducible and welltolerated method for 2/3 partial hepatectomy in mice
    • PMID:18600221
    • Mitchell C, Willenbring H. A reproducible and welltolerated method for 2/3 partial hepatectomy in mice. Nat Protoc 2008; 3:1167-70; PMID:18600221; http://dx.doi.org/10.1038/nprot.2008.80
    • (2008) Nat Protoc , vol.3 , pp. 1167-1170
    • Mitchell, C.1    Willenbring, H.2


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