Cladosporol A, a new peroxisome proliferator-activated receptor γ (PPARγ) ligand, inhibits colorectal cancer cells proliferation through β-catenin/TCF pathway inactivation

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 7, 2014, Pages 2361-2372

  Zurlo, Diana ^a   Assante, Gemma ^b   Moricca, Salvatore ^c   Colantuoni, Vittorio ^a   Lupo, Angelo ^a  

^a UNIVERSITY OF SANNIO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cell proliferation; Cladosporol A; E cadherin; Transcription; catenin

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA CATENIN; CLADOSPOROL A; CYCLIN DEPENDENT KINASE INHIBITOR 1; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; UVOMORULIN;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL INTERACTION; CELL NUCLEUS; COLORECTAL CANCER; CONTROLLED STUDY; CYCLIN DEPENDENT KINASE INHIBITOR 1 GENE; E CADHERIN GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; UPREGULATION;

CELL PROLIFERATION; CLADOSPOROL A; E-CADHERIN; P21(WAF1/CIP1); TRANSCRIPTION; Β-CATENIN;

BETA CATENIN; CELL PROLIFERATION; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; LIGANDS; NAPHTHALENES; PPAR GAMMA; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TCF TRANSCRIPTION FACTORS;

EID: 84899998499     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.04.007     Document Type: Article

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