p53-dependent but ATM-independent inhibition of DNA synthesis and G2 arrest in cadmium-treated human fibroblasts

Toxicology and Applied Pharmacology

Volumn 218, Issue 2, 2007, Pages 174-185

  Cao, Feng ^a,b   Zhou, Tong ^b   Simpson, Dennis ^b   Zhou, Yingchun ^b   Boyer, Jayne ^b   Chen, Bo ^a,b   Jin, Taiyi ^a   Cordeiro Stone, Marila ^b   Kaufmann, William ^b  

^a Medical Center   (China)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Ataxia telangiectasia; Cadmium; Checkpoint; DNA synthesis; Fibroblasts; Gadd45 ; p53

Indexed keywords

ATM PROTEIN; CADMIUM; CELL DNA; MESSENGER RNA; PROTEIN P53;

ARTICLE; ATAXIA TELANGIECTASIA; CELL CYCLE G2 PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPLICATION; DNA SYNTHESIS INHIBITION; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSACTIVATION;

ATAXIA TELANGIECTASIA; BLOTTING, WESTERN; CADMIUM; CELL CYCLE PROTEINS; CELL LINE; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; COMET ASSAY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA; DNA DAMAGE; DNA REPLICATION; DNA-BINDING PROTEINS; FIBROBLASTS; G1 PHASE; G2 PHASE; HUMANS; PLASMIDS; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 33846695111     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.10.031     Document Type: Article

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