Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G 2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation

Journal of Nutrition

Volumn 134, Issue 11, 2004, Pages 3121-3126

  Visanji, James M ^a   Duthie, Susan J ^b   Pirie, Lynn ^b   Thompson, David G ^a   Padfield, Philip J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Checkpoints; DNA damage; Isothiocyanates; Proliferation

Indexed keywords

BENZYL ISOTHIOCYANATE; CHECKPOINT KINASE 2; ISOTHIOCYANIC ACID DERIVATIVE; NOCODAZOLE; PHENETHYL ISOTHIOCYANATE; PROTEIN P21;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BRASSICA; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL SYNCHRONIZATION; CELL VIABILITY; CONTROLLED STUDY; DIET; DNA DAMAGE; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; DRUG ACTIVITY; DRUG EFFECT; HUMAN; HUMAN CELL; IC 50; METAPHASE; PHYTOCHEMISTRY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; VEGETABLE;

BRASSICA;

EID: 7944237475     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/134.11.3121     Document Type: Article

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