-
1
-
-
33847737716
-
DNA damage checkpoints: from initiation to recovery or adaptation
-
Bartek J., and Lukas J. DNA damage checkpoints: from initiation to recovery or adaptation. Curr. Opin. Cell Biol. 19 (2007) 238-245
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
2
-
-
0034738420
-
p21(WAF1/Cip1): more than a break to the cell cycle?
-
Dotto G.P. p21(WAF1/Cip1): more than a break to the cell cycle?. Biochim. Biophys. Acta 1471 (2000) M43-56
-
(2000)
Biochim. Biophys. Acta
, vol.1471
-
-
Dotto, G.P.1
-
3
-
-
0037304898
-
New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?
-
Coqueret O. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?. Trends Cell. Biol. 13 (2003) 65-70
-
(2003)
Trends Cell. Biol.
, vol.13
, pp. 65-70
-
-
Coqueret, O.1
-
4
-
-
0033564697
-
CDK inhibitors: positive and negative regulators of G1 phase progression
-
Sherr C.J., and Roberts J.M. CDK inhibitors: positive and negative regulators of G1 phase progression. Genes Dev. 13 (1999) 1501-1512
-
(1999)
Genes Dev.
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
5
-
-
38849187293
-
CDK inhibitors: cell cycle regulators and beyond
-
Besson A., Dowdy S.F., and Roberts J.M. CDK inhibitors: cell cycle regulators and beyond. Dev. Cell 14 (2008) 159-169
-
(2008)
Dev. Cell
, vol.14
, pp. 159-169
-
-
Besson, A.1
Dowdy, S.F.2
Roberts, J.M.3
-
6
-
-
0027496935
-
The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper J.W., Adami G., Wei N., Keyomarsi K., and Elledge S. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75 (1993) 805-816
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.5
-
7
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppressor
-
el-Deiry W., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzier K.W., and Volgestein B. WAF1, a potential mediator of p53 tumor suppressor. Cell 75 (1993) 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzier, K.W.9
Volgestein, B.10
-
8
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
Noda A., Ning Y., Venalle S.F., Pereira-Smith O.M., and Smith J.R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211 (1994) 90-98
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venalle, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
9
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
Chen J., Jackson P.K., Kirschner M.W., and Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 374 (1995) 386-388
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
10
-
-
0029021714
-
Cip1 cyclin-dependent kinase inhibitor
-
Cip1 cyclin-dependent kinase inhibitor. Oncogene 10 (1995) 2281-2287
-
(1995)
Oncogene
, vol.10
, pp. 2281-2287
-
-
Goubin, F.1
Ducommun, B.2
-
12
-
-
0029948612
-
p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity
-
Fotedar R., Fitzgerald P., Rousselle T., Cannella D., Dorée M., Messier H., and Fotedar A. p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity. Oncogene 12 (1996) 2155-2164
-
(1996)
Oncogene
, vol.12
, pp. 2155-2164
-
-
Fotedar, R.1
Fitzgerald, P.2
Rousselle, T.3
Cannella, D.4
Dorée, M.5
Messier, H.6
Fotedar, A.7
-
13
-
-
0027981476
-
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme
-
Flores-Rozas H., Kelman Z., Dean F.B., Pan Z.Q., Harper J.W., Elledge S.J., O'Donnell M., and Hurwitz J. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 8655-8659
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 8655-8659
-
-
Flores-Rozas, H.1
Kelman, Z.2
Dean, F.B.3
Pan, Z.Q.4
Harper, J.W.5
Elledge, S.J.6
O'Donnell, M.7
Hurwitz, J.8
-
14
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
Waga S., Hannon G.J., Beach D., and Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369 (1994) 574-578
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
15
-
-
0029063745
-
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21
-
Luo Y., Hurwitz J., and Massagué J. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21. Nature 375 (1995) 159-161
-
(1995)
Nature
, vol.375
, pp. 159-161
-
-
Luo, Y.1
Hurwitz, J.2
Massagué, J.3
-
16
-
-
0029670606
-
Cip1/Waf1 peptide domains required for cyclin E/cdk2 and PCNA interactions
-
Cip1/Waf1 peptide domains required for cyclin E/cdk2 and PCNA interactions. Oncogene 12 (1996) 595-607
-
(1996)
Oncogene
, vol.12
, pp. 595-607
-
-
Chen, L.T.1
Akamatsu, M.2
Smith, M.L.3
Lung, F.D.T.4
Duba, D.5
Roller, P.P.6
Fornace Jr., A.J.7
O'Connor, P.M.8
-
17
-
-
33744462103
-
The fellowship of the rings: distinct pools of proliferating cell nuclear antigen (PCNA) trimer at work
-
Prosperi E. The fellowship of the rings: distinct pools of proliferating cell nuclear antigen (PCNA) trimer at work. FASEB J. 20 (2006) 833-837
-
(2006)
FASEB J.
, vol.20
, pp. 833-837
-
-
Prosperi, E.1
-
18
-
-
34249066085
-
PCNA, the maestro of replication fork
-
Moldovan G.L., Pfander B., and Jentsch S. PCNA, the maestro of replication fork. Cell 129 (2007) 665-679
-
(2007)
Cell
, vol.129
, pp. 665-679
-
-
Moldovan, G.L.1
Pfander, B.2
Jentsch, S.3
-
19
-
-
0141683528
-
Cip1 is a determinant for target protein recognition
-
Cip1 is a determinant for target protein recognition. ChemBioChem. 4 (2003) 863-869
-
(2003)
ChemBioChem.
, vol.4
, pp. 863-869
-
-
Esteve, V.1
Canela, N.2
Rodriguez-Vilarrupla, A.3
Aliguè, R.4
Agell, N.5
Mingarro, I.6
Bachs, O.7
Perz-Payà, E.8
-
20
-
-
33745150087
-
The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability
-
Child E.S., and Mann D.J. The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability. Cell Cycle 12 (2006) 1313-1319
-
(2006)
Cell Cycle
, vol.12
, pp. 1313-1319
-
-
Child, E.S.1
Mann, D.J.2
-
21
-
-
0028849274
-
p21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman T., Kinzler K.W., and Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55 (1995) 5187-5190
-
(1995)
Cancer Res.
, vol.55
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
22
-
-
0033514441
-
Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation
-
Brugarolas J., Moberg K., Boyd S.D., Taya Y., Jacks T., and Lees J.A. Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 1002-1007
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 1002-1007
-
-
Brugarolas, J.1
Moberg, K.2
Boyd, S.D.3
Taya, Y.4
Jacks, T.5
Lees, J.A.6
-
23
-
-
0027229136
-
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
-
Ewen M.E., Sluss H.K., Sherr C.J., Matsushime H., Kato J., and Livingston D.M. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73 (1993) 487-497
-
(1993)
Cell
, vol.73
, pp. 487-497
-
-
Ewen, M.E.1
Sluss, H.K.2
Sherr, C.J.3
Matsushime, H.4
Kato, J.5
Livingston, D.M.6
-
24
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
el-Deiry W.S., Harper J.W., O'Connor P.M., Velculescu V.E., Canman C.E., Jackman J., Pietenpol J.A., Burrell M., Hill D.E., Wang Y., Wiman K.G., Mercer W.E., Kastan M.B., Kohn K.W., Elledge S.J., Kinzler K.W., and Vogelstein B. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 54 (1994) 1169-1174
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
el-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
Wiman, K.G.11
Mercer, W.E.12
Kastan, M.B.13
Kohn, K.W.14
Elledge, S.J.15
Kinzler, K.W.16
Vogelstein, B.17
-
26
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J., Chandrasekaran C., Gordon J.I., Beach D., Jacks I., and Hannon G.J. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377 (1995) 552-557
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, I.5
Hannon, G.J.6
-
27
-
-
38749103066
-
p21 inhibits CDK1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
-
Satyanarayana A., Hilton M.B., and Kaldis P. p21 inhibits CDK1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint. Mol. Biol. Cell 19 (2008) 65-77
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 65-77
-
-
Satyanarayana, A.1
Hilton, M.B.2
Kaldis, P.3
-
28
-
-
0030592544
-
Structure of the C-terminal region of p21waf1/cip1 complexed with human PCNA
-
Gulbis J.M., Kelman Z., Hurtwitz J., O'Donnel M., and Kuriyan J. Structure of the C-terminal region of p21waf1/cip1 complexed with human PCNA. Cell 87 (1996) 297-306
-
(1996)
Cell
, vol.87
, pp. 297-306
-
-
Gulbis, J.M.1
Kelman, Z.2
Hurtwitz, J.3
O'Donnel, M.4
Kuriyan, J.5
-
29
-
-
0031865131
-
Functional sites of human PCNA which interact with p21 (Cip1/Waf1), DNA polymerase delta and replication factor C
-
Oku T., Ikeda S., Sasaki H., Fukuda K., Morioka H., Ohtsuka E., Yoshikawa H., and Tsurimoto T. Functional sites of human PCNA which interact with p21 (Cip1/Waf1), DNA polymerase delta and replication factor C. Gene Cells 3 (1998) 357-369
-
(1998)
Gene Cells
, vol.3
, pp. 357-369
-
-
Oku, T.1
Ikeda, S.2
Sasaki, H.3
Fukuda, K.4
Morioka, H.5
Ohtsuka, E.6
Yoshikawa, H.7
Tsurimoto, T.8
-
30
-
-
0029257341
-
A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen
-
Warbrick E., Lane D.P., Glover D.M., and Cox L.S. A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen. Curr. Biol. 5 (1995) 275-282
-
(1995)
Curr. Biol.
, vol.5
, pp. 275-282
-
-
Warbrick, E.1
Lane, D.P.2
Glover, D.M.3
Cox, L.S.4
-
31
-
-
0029873287
-
A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo
-
Chen J., Peters R., Saha P., Lee P., Theodoras A., Pagano M., Wagner G., and Dutta A. A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo. Nucleic Acids Res. 24 (1996) 1727-1733
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 1727-1733
-
-
Chen, J.1
Peters, R.2
Saha, P.3
Lee, P.4
Theodoras, A.5
Pagano, M.6
Wagner, G.7
Dutta, A.8
-
32
-
-
0032556952
-
p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
-
Cayrol C., Knibiehler M., and Ducommun B. p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells. Oncogene 16 (1998) 311-320
-
(1998)
Oncogene
, vol.16
, pp. 311-320
-
-
Cayrol, C.1
Knibiehler, M.2
Ducommun, B.3
-
33
-
-
0033609369
-
Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway
-
Rousseau D., Cannella D., Boulaire J., Fitzgerald P., Fotedar A., and Fotedar R. Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway. Oncogene 18 (1999) 4313-4325
-
(1999)
Oncogene
, vol.18
, pp. 4313-4325
-
-
Rousseau, D.1
Cannella, D.2
Boulaire, J.3
Fitzgerald, P.4
Fotedar, A.5
Fotedar, R.6
-
34
-
-
0035325262
-
Inhibition of cell proliferation by the PCNA-binding protein region of p21 expressed as a GFP miniprotein
-
Mattock H., Lane D.P., and Warbrick E. Inhibition of cell proliferation by the PCNA-binding protein region of p21 expressed as a GFP miniprotein. Exp. Cell Res. 265 (2001) 234-241
-
(2001)
Exp. Cell Res.
, vol.265
, pp. 234-241
-
-
Mattock, H.1
Lane, D.P.2
Warbrick, E.3
-
35
-
-
0347160176
-
CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase δ at the G1/S phase transition
-
CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase δ at the G1/S phase transition. Cell Cycle 2 (2003) 596-603
-
(2003)
Cell Cycle
, vol.2
, pp. 596-603
-
-
Cazzalini, O.1
Perucca, P.2
Riva, F.3
Stivala, L.A.4
Bianchi, L.5
Vannini, V.6
Ducommun, B.7
Prosperi, E.8
-
37
-
-
1242294418
-
Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block
-
Gottifredi V., McKinney K., Poyurovsky M.V., and Prives C. Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block. J. Biol. Chem. 279 (2004) 5802-5810
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5802-5810
-
-
Gottifredi, V.1
McKinney, K.2
Poyurovsky, M.V.3
Prives, C.4
-
38
-
-
33645230895
-
Direct interaction of p21 with p50, the small subunit of human DNA polymerase delta
-
Li H., Xie B., Rahmeh A., Zhou Y., and Lee M.Y.W.T. Direct interaction of p21 with p50, the small subunit of human DNA polymerase delta. Cell Cycle 5 (2006) 428-436
-
(2006)
Cell Cycle
, vol.5
, pp. 428-436
-
-
Li, H.1
Xie, B.2
Rahmeh, A.3
Zhou, Y.4
Lee, M.Y.W.T.5
-
39
-
-
1542330106
-
cip1/waf1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition
-
cip1/waf1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition. Genes Cells 9 (2004) 131-142
-
(2004)
Genes Cells
, vol.9
, pp. 131-142
-
-
Arima, Y.1
Hirota, T.2
Bronner, C.3
Mousli, M.4
Fujiwara, T.5
Niwa, S.6
Ishikawa, H.7
Saya, H.8
-
40
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F., Dutriaux A., Lengauer C., Waldman T., Zhou S., Brown J.P., Sedivy J.M., Kinzler K.W., and Vogelstein B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282 (1998) 1497-1501
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
41
-
-
0031961995
-
Cip1/Waf1 at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
-
Cip1/Waf1 at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol. 18 (1998) 629-643
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 629-643
-
-
Niculescu, A.B.1
Chen, X.2
Smeets, M.3
Hengst, L.4
Prives, C.5
Reed, S.I.6
-
42
-
-
0030011128
-
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman T., Lengauer C., Kinzler K.W., and Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381 (1996) 713-716
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
43
-
-
0029058587
-
Inhibition of cyclin-dependent kinases by p21
-
Harper J.W., Elledge S.J., Keyomarsi K., Dynlacht B., Tsai L.H., Zhang P., Dobrowolski S., Bai C., Connell-Crowley L., Swindell E., Fox M.P., and Wei N. Inhibition of cyclin-dependent kinases by p21. Mol. Biol. Cell 6 (1995) 387-400
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 387-400
-
-
Harper, J.W.1
Elledge, S.J.2
Keyomarsi, K.3
Dynlacht, B.4
Tsai, L.H.5
Zhang, P.6
Dobrowolski, S.7
Bai, C.8
Connell-Crowley, L.9
Swindell, E.10
Fox, M.P.11
Wei, N.12
-
44
-
-
0034730246
-
p21 inhibits Thr161 phosphorylation of Cdc2 to enforce the G2 DNA damage checkpoint
-
Smits V.A., Klompmaker R., Vallenius T., Rijksen G., Mäkela T.P., and Medema R.H. p21 inhibits Thr161 phosphorylation of Cdc2 to enforce the G2 DNA damage checkpoint. J. Biol. Chem. 275 (2000) 30638-30643
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30638-30643
-
-
Smits, V.A.1
Klompmaker, R.2
Vallenius, T.3
Rijksen, G.4
Mäkela, T.P.5
Medema, R.H.6
-
46
-
-
0042025008
-
Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts
-
Baus F., Gire V., Fisher D., Piette J., and Dulić V. Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts. EMBO J. 22 (2003) 3992-4002
-
(2003)
EMBO J.
, vol.22
, pp. 3992-4002
-
-
Baus, F.1
Gire, V.2
Fisher, D.3
Piette, J.4
Dulić, V.5
-
47
-
-
4344574113
-
p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress
-
Charrier-Savournin F.B., Château M.T., Gire V., Sedivy J., Piette J., and Dulic V. p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress. Mol. Biol. Cell 15 (2004) 3965-3976
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3965-3976
-
-
Charrier-Savournin, F.B.1
Château, M.T.2
Gire, V.3
Sedivy, J.4
Piette, J.5
Dulic, V.6
-
49
-
-
65249099623
-
DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest
-
Lee J., Kim A.K., Barbier V., Fotedar A., and Fotedar R. DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest. Mol. Biol. Cell 20 (2009) 1891-1902
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1891-1902
-
-
Lee, J.1
Kim, A.K.2
Barbier, V.3
Fotedar, A.4
Fotedar, R.5
-
50
-
-
0141743327
-
Differential effects of cell cycle regulatory protein p21(WAF1/Cip1) on apoptosis and sensitivity to cancer chemotherapy
-
Liu S., Bishop W.R., and Liu M. Differential effects of cell cycle regulatory protein p21(WAF1/Cip1) on apoptosis and sensitivity to cancer chemotherapy. Drug Resist. Update 6 (2003) 183-195
-
(2003)
Drug Resist. Update
, vol.6
, pp. 183-195
-
-
Liu, S.1
Bishop, W.R.2
Liu, M.3
-
52
-
-
40549111934
-
Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death
-
Garner E., and Raj K. Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death. Cell Cycle 7 (2008) 277-282
-
(2008)
Cell Cycle
, vol.7
, pp. 277-282
-
-
Garner, E.1
Raj, K.2
-
53
-
-
67649424560
-
p21 in cancer: intricate networks and multiple activities
-
Abbas T., and Dutta A. p21 in cancer: intricate networks and multiple activities. Nat. Rev. Cancer 9 (2009) 400-414
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 400-414
-
-
Abbas, T.1
Dutta, A.2
-
54
-
-
0030842655
-
Cell-cycle arrest versus cell death in cancer therapy
-
Waldman T., Zhang Y., Dillehay L., Yu J., Kinzler K., Vogelstein B., and Williams J. Cell-cycle arrest versus cell death in cancer therapy. Nat. Med. 3 (1997) 1034-1036
-
(1997)
Nat. Med.
, vol.3
, pp. 1034-1036
-
-
Waldman, T.1
Zhang, Y.2
Dillehay, L.3
Yu, J.4
Kinzler, K.5
Vogelstein, B.6
Williams, J.7
-
55
-
-
0032572789
-
Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP
-
Suzuki A., Tsutomi Y., Akahane K., Araki T., and Miura M. Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP. Oncogene 17 (1998) 931-939
-
(1998)
Oncogene
, vol.17
, pp. 931-939
-
-
Suzuki, A.1
Tsutomi, Y.2
Akahane, K.3
Araki, T.4
Miura, M.5
-
56
-
-
0033521925
-
Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21
-
Suzuki A., Tsutomi Y., Miura M., and Akahane K. Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21. Oncogene 18 (1999) 1239-1244
-
(1999)
Oncogene
, vol.18
, pp. 1239-1244
-
-
Suzuki, A.1
Tsutomi, Y.2
Miura, M.3
Akahane, K.4
-
57
-
-
44149110803
-
Caspase 2 is both required for p53-mediated apoptosis and downregulated by p53 in a p21-dependent manner
-
Baptiste-Okoh N., Barsotti A.M., and Prives C. Caspase 2 is both required for p53-mediated apoptosis and downregulated by p53 in a p21-dependent manner. Cell Cycle 7 (2008) 1133-1138
-
(2008)
Cell Cycle
, vol.7
, pp. 1133-1138
-
-
Baptiste-Okoh, N.1
Barsotti, A.M.2
Prives, C.3
-
58
-
-
0032563286
-
Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis
-
Gervais J.L., Seth P., and Zhang H. Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis. J. Biol. Chem. 273 (1998) 19207-19212
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19207-19212
-
-
Gervais, J.L.1
Seth, P.2
Zhang, H.3
-
59
-
-
0032012062
-
Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade
-
Levkau B., Koyama H., Raines E.W., Clurman B.E., Herren B., Orth K., Roberts J.M., and Ross R. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. Mol. Cell 1 (1998) 553-563
-
(1998)
Mol. Cell
, vol.1
, pp. 553-563
-
-
Levkau, B.1
Koyama, H.2
Raines, E.W.3
Clurman, B.E.4
Herren, B.5
Orth, K.6
Roberts, J.M.7
Ross, R.8
-
60
-
-
0034730527
-
Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells
-
Jin Y.H., Yoo K.J., Lee Y.H., and Lee S.K. Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells. J. Biol. Chem. 275 (2000) 30256-30263
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30256-30263
-
-
Jin, Y.H.1
Yoo, K.J.2
Lee, Y.H.3
Lee, S.K.4
-
61
-
-
0033104495
-
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
-
Asada M., Yamada T., Ichijo H., Delia D., Miyazono K., Fukumuro K., and Mizutani S. Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J. 18 (1999) 1223-1234
-
(1999)
EMBO J.
, vol.18
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
Delia, D.4
Miyazono, K.5
Fukumuro, K.6
Mizutani, S.7
-
62
-
-
0038094504
-
Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)
-
Huang S., Shu L., Dilling M.B., Easton J., Harwood F.C., Ichijo H., and Houghton P.J. Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). Mol. Cell 11 (2003) 1491-1501
-
(2003)
Mol. Cell
, vol.11
, pp. 1491-1501
-
-
Huang, S.1
Shu, L.2
Dilling, M.B.3
Easton, J.4
Harwood, F.C.5
Ichijo, H.6
Houghton, P.J.7
-
63
-
-
0037225749
-
Association of JNK1 with p21waf1 and p53: modulation of JNK1 activity
-
Xue Y., Ramaswamy N.T., Hong X., and Pelling J.C. Association of JNK1 with p21waf1 and p53: modulation of JNK1 activity. Mol. Carcinog. 36 (2003) 38-44
-
(2003)
Mol. Carcinog.
, vol.36
, pp. 38-44
-
-
Xue, Y.1
Ramaswamy, N.T.2
Hong, X.3
Pelling, J.C.4
-
64
-
-
34247577963
-
Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo
-
Zhan J., Easton J.B., Huang S., Mishra A., Xiao L., Lacy E.R., Kriwacki R.W., and Houghton P.J. Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo. Mol. Cell. Biol. 27 (2007) 3530-3541
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3530-3541
-
-
Zhan, J.1
Easton, J.B.2
Huang, S.3
Mishra, A.4
Xiao, L.5
Lacy, E.R.6
Kriwacki, R.W.7
Houghton, P.J.8
-
65
-
-
24744462701
-
Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells
-
Le H.V., Minn A.J., and Massagué J. Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. J. Biol. Chem. 280 (2005) 32018-32025
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32018-32025
-
-
Le, H.V.1
Minn, A.J.2
Massagué, J.3
-
66
-
-
33845777950
-
p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation
-
Sohn D., Essmann F., Schulze-Osthoff K., and Jänicke R.U. p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation. Cancer Res. 66 (2006) 11254-11262
-
(2006)
Cancer Res.
, vol.66
, pp. 11254-11262
-
-
Sohn, D.1
Essmann, F.2
Schulze-Osthoff, K.3
Jänicke, R.U.4
-
68
-
-
0242671511
-
An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells
-
Fan Y., Borowsky A.D., and Weiss R.H. An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells. Mol. Cancer Ther. 2 (2003) 773-782
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 773-782
-
-
Fan, Y.1
Borowsky, A.D.2
Weiss, R.H.3
-
69
-
-
0347628818
-
p21Waf1/Cip1 as a therapeutic target in breast and other cancers
-
Weiss R.H. p21Waf1/Cip1 as a therapeutic target in breast and other cancers. Cancer Cell 4 (2003) 425-429
-
(2003)
Cancer Cell
, vol.4
, pp. 425-429
-
-
Weiss, R.H.1
-
70
-
-
0037427570
-
Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1)
-
Weiss R.H., Marshall D., Howard L., Corbacho A.M., Cheung A.T., and Sawai E.T. Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1). Cancer Lett. 189 (2003) 39-48
-
(2003)
Cancer Lett.
, vol.189
, pp. 39-48
-
-
Weiss, R.H.1
Marshall, D.2
Howard, L.3
Corbacho, A.M.4
Cheung, A.T.5
Sawai, E.T.6
-
71
-
-
44649118573
-
Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53
-
Park S.H., Park J.Y., and Weiss R.H. Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53. J. Urol. 180 (2008) 352-360
-
(2008)
J. Urol.
, vol.180
, pp. 352-360
-
-
Park, S.H.1
Park, J.Y.2
Weiss, R.H.3
-
72
-
-
33847649218
-
Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance
-
Lin P.Y., Fosmire S.P., Park S.H., Park J.Y., Baksh S., Modiano J.F., and Weiss R.H. Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance. Mol. Cancer 14 (2007) 6-16
-
(2007)
Mol. Cancer
, vol.14
, pp. 6-16
-
-
Lin, P.Y.1
Fosmire, S.P.2
Park, S.H.3
Park, J.Y.4
Baksh, S.5
Modiano, J.F.6
Weiss, R.H.7
-
73
-
-
0037126303
-
Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
-
Seoane J., Le H.V., and Massagué J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 419 (2002) 729-734
-
(2002)
Nature
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massagué, J.3
-
74
-
-
0033621560
-
p21WAF1/CIP1 antisense therapy radiosensitizes human colon cancer by converting growth arrest to apoptosis
-
Tian H., Wittmack E.K., and Jorgensen T.J. p21WAF1/CIP1 antisense therapy radiosensitizes human colon cancer by converting growth arrest to apoptosis. Cancer Res. 60 (2000) 679-684
-
(2000)
Cancer Res.
, vol.60
, pp. 679-684
-
-
Tian, H.1
Wittmack, E.K.2
Jorgensen, T.J.3
-
75
-
-
24744454815
-
CIP1/WAF1 in apoptosis
-
CIP1/WAF1 in apoptosis. Leuk. Res. 29 (2005) 1237-1238
-
(2005)
Leuk. Res.
, vol.29
, pp. 1237-1238
-
-
Gartel, A.L.1
-
76
-
-
0033577936
-
Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells
-
Fotedar R., Brickner H., Saadatmandi N., Rousselle T., Diederich L., Munshi A., Jung B., Reed J.C., and Fotedar A. Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells. Oncogene 18 (1999) 3652-3658
-
(1999)
Oncogene
, vol.18
, pp. 3652-3658
-
-
Fotedar, R.1
Brickner, H.2
Saadatmandi, N.3
Rousselle, T.4
Diederich, L.5
Munshi, A.6
Jung, B.7
Reed, J.C.8
Fotedar, A.9
-
77
-
-
0942290420
-
P21(WAF1/CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells
-
Chopin V., Toillon R.A., Jouy N., and Le Bourhis X. P21(WAF1/CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells. Oncogene 23 (2004) 21-29
-
(2004)
Oncogene
, vol.23
, pp. 21-29
-
-
Chopin, V.1
Toillon, R.A.2
Jouy, N.3
Le Bourhis, X.4
-
78
-
-
49549104441
-
A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate
-
Kraljevic Pavelic S., Cacev T., and Kralj M. A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate. Cancer Gene Ther. 15 (2008) 576-590
-
(2008)
Cancer Gene Ther.
, vol.15
, pp. 576-590
-
-
Kraljevic Pavelic, S.1
Cacev, T.2
Kralj, M.3
-
79
-
-
0042197268
-
Are p27 and p21 cytoplasmic oncoproteins?
-
Blagosklonny M.V. Are p27 and p21 cytoplasmic oncoproteins?. Cell Cycle 1 (2002) 391-393
-
(2002)
Cell Cycle
, vol.1
, pp. 391-393
-
-
Blagosklonny, M.V.1
-
80
-
-
67349136037
-
Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair
-
Savio M., Coppa T., Cazzalini O., Perucca P., Necchi D., Nardo T., Stivala L.A., and Prosperi E. Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair. DNA Repair 8 (2009) 778-785
-
(2009)
DNA Repair
, vol.8
, pp. 778-785
-
-
Savio, M.1
Coppa, T.2
Cazzalini, O.3
Perucca, P.4
Necchi, D.5
Nardo, T.6
Stivala, L.A.7
Prosperi, E.8
-
81
-
-
0036045455
-
p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells
-
Martinez L.A., Yang J., Vazquez E.S., Rodriguez-Vargas M.del.C., Olive M., Hsieh J.T., Logothetis C.J., and Navone N.M. p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells. Carcinogenesis 23 (2002) 1289-1296
-
(2002)
Carcinogenesis
, vol.23
, pp. 1289-1296
-
-
Martinez, L.A.1
Yang, J.2
Vazquez, E.S.3
Rodriguez-Vargas, M.del.C.4
Olive, M.5
Hsieh, J.T.6
Logothetis, C.J.7
Navone, N.M.8
-
82
-
-
67651154117
-
Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis
-
Lee E.W., Lee M.S., Camus S., Ghim J., Yang M.R., Oh W., Ha N.C., Lane D.P., and Song J. Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis. EMBO J. 28 (2009) 2100-2113
-
(2009)
EMBO J.
, vol.28
, pp. 2100-2113
-
-
Lee, E.W.1
Lee, M.S.2
Camus, S.3
Ghim, J.4
Yang, M.R.5
Oh, W.6
Ha, N.C.7
Lane, D.P.8
Song, J.9
-
83
-
-
67549142261
-
Life and death partners: apoptosis, autophagy and the cross-talk between them
-
Eisenberg-Lerner A., Bialik S., Simon U.K., and Kimchi A. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ. 16 (2009) 966-975
-
(2009)
Cell Death Differ.
, vol.16
, pp. 966-975
-
-
Eisenberg-Lerner, A.1
Bialik, S.2
Simon, U.K.3
Kimchi, A.4
-
84
-
-
38049148611
-
Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy
-
Fujiwara K., Daido S., Yamamoto A., Kobayashi R., Yokoyama T., Aoki H., Iwado E., Shinojima N., Kondo Y., and Kondo S. Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy. J. Biol. Chem. 283 (2008) 388-397
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 388-397
-
-
Fujiwara, K.1
Daido, S.2
Yamamoto, A.3
Kobayashi, R.4
Yokoyama, T.5
Aoki, H.6
Iwado, E.7
Shinojima, N.8
Kondo, Y.9
Kondo, S.10
-
85
-
-
53549104898
-
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling
-
Zhang G., Park M.A., Mitchell C., Walker T., Hamed H., Studer E., Graf M., Rahmani M., Gupta S., Hylemon P.B., Fisher P.B., Grant S., and Dent P. Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling. J. Biol. Chem. 283 (2008) 24343-24358
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24343-24358
-
-
Zhang, G.1
Park, M.A.2
Mitchell, C.3
Walker, T.4
Hamed, H.5
Studer, E.6
Graf, M.7
Rahmani, M.8
Gupta, S.9
Hylemon, P.B.10
Fisher, P.B.11
Grant, S.12
Dent, P.13
-
86
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
Green D.R., and Kroemer G. Cytoplasmic functions of the tumour suppressor p53. Nature 458 (2009) 1127-1130
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
87
-
-
57649184088
-
Control of autophagy by oncogenes and tumor suppressor genes
-
Maiuri M.C., Tasdemir E., Criollo A., Morselli E., Vicencio J.M., Carnuccio R., and Kroemer G. Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ. 16 (2009) 87-93
-
(2009)
Cell Death Differ.
, vol.16
, pp. 87-93
-
-
Maiuri, M.C.1
Tasdemir, E.2
Criollo, A.3
Morselli, E.4
Vicencio, J.M.5
Carnuccio, R.6
Kroemer, G.7
-
88
-
-
0036048524
-
(WAF1/CIP1/SDI1)
-
(WAF1/CIP1/SDI1). Cell Cycle 1 (2002) 39-41
-
(2002)
Cell Cycle
, vol.1
, pp. 39-41
-
-
Perkins, N.D.1
-
89
-
-
14844365000
-
p21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha
-
Fritah A., Saucier C., Mester J., Redeuilh G., and Sabbah M. p21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha. Mol. Cell. Biol. 25 (2005) 2419-2430
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2419-2430
-
-
Fritah, A.1
Saucier, C.2
Mester, J.3
Redeuilh, G.4
Sabbah, M.5
-
90
-
-
37549004570
-
p21 (CDKN1A) is a negative regulator of p53 stability
-
Broude E.V., Demidenko Z.N., Vivo C., Swift M.E., Davis B.M., Blagosklonny M.V., and Roninson I.B. p21 (CDKN1A) is a negative regulator of p53 stability. Cell Cycle 6 (2007) 1468-1471
-
(2007)
Cell Cycle
, vol.6
, pp. 1468-1471
-
-
Broude, E.V.1
Demidenko, Z.N.2
Vivo, C.3
Swift, M.E.4
Davis, B.M.5
Blagosklonny, M.V.6
Roninson, I.B.7
-
92
-
-
0029670837
-
p21 disrupts the interaction between cdk2 and the E2F-p130 complex
-
Shiyanov P., Bagchi S., Adami G., Kokontis J., Hay N., Arroyo M., Morozov A., and Raychaudhuri P. p21 disrupts the interaction between cdk2 and the E2F-p130 complex. Mol. Cell. Biol. 16 (1996) 737-744
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 737-744
-
-
Shiyanov, P.1
Bagchi, S.2
Adami, G.3
Kokontis, J.4
Hay, N.5
Arroyo, M.6
Morozov, A.7
Raychaudhuri, P.8
-
93
-
-
0033598444
-
Control of E2F activity by p21Waf1/Cip1
-
Delavaine L., and La Thangue N.B. Control of E2F activity by p21Waf1/Cip1. Oncogene 18 (1999) 5381-5392
-
(1999)
Oncogene
, vol.18
, pp. 5381-5392
-
-
Delavaine, L.1
La Thangue, N.B.2
-
94
-
-
0034616116
-
Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription
-
Kitaura H., Shinshi M., Uchikoshi Y., Ono T., Iguchi-Ariga S.M., and Ariga H. Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription. J. Biol. Chem. 275 (2000) 10477-10483
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10477-10483
-
-
Kitaura, H.1
Shinshi, M.2
Uchikoshi, Y.3
Ono, T.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
95
-
-
0036047982
-
Identification of promoter elements responsible for transcriptional inhibition of polo-like kinase 1 and topoisomerase II alpha genes by p21(WAF1/CIP1/SDI1)
-
Zhu H., Chang B.D., Uchiumi T., and Roninson I.B. Identification of promoter elements responsible for transcriptional inhibition of polo-like kinase 1 and topoisomerase II alpha genes by p21(WAF1/CIP1/SDI1). Cell Cycle 1 (2002) 59-66
-
(2002)
Cell Cycle
, vol.1
, pp. 59-66
-
-
Zhu, H.1
Chang, B.D.2
Uchiumi, T.3
Roninson, I.B.4
-
96
-
-
27844470637
-
Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis
-
Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis. J. Biol. Chem. 280 (2005) 37725-37731
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37725-37731
-
-
Wang, J.1
Devgan, V.2
Corrado, M.3
Prabhu, N.4
El-Deiry, W.S.5
Riccardi, C.6
Pandolfi, P.P.7
Missero, C.8
Dotto, G.P.9
-
98
-
-
0030614504
-
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
-
Perkins N.D., Felzien L.K., Betts J.C., Leung K., Beach D.H., and Nabel G.J. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science 275 (1997) 523-527
-
(1997)
Science
, vol.275
, pp. 523-527
-
-
Perkins, N.D.1
Felzien, L.K.2
Betts, J.C.3
Leung, K.4
Beach, D.H.5
Nabel, G.J.6
-
99
-
-
0037158891
-
Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases
-
Redeuilh G., Attia A., Mester J., and Sabbah M. Transcriptional activation by the oestrogen receptor alpha is modulated through inhibition of cyclin-dependent kinases. Oncogene 21 (2002) 5773-5782
-
(2002)
Oncogene
, vol.21
, pp. 5773-5782
-
-
Redeuilh, G.1
Attia, A.2
Mester, J.3
Sabbah, M.4
-
100
-
-
0141963319
-
Concomitant increase of histone acetyltransferase activity and degradation of p300 during retinoic acid-induced differentiation of F9 cells
-
Brouillard F., and Cremisi C.E. Concomitant increase of histone acetyltransferase activity and degradation of p300 during retinoic acid-induced differentiation of F9 cells. J. Biol. Chem. 278 (2003) 39509-39516
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39509-39516
-
-
Brouillard, F.1
Cremisi, C.E.2
-
101
-
-
17944373135
-
CBP/p300 and muscle differentiation: no HAT, no muscle
-
Polesskaya A., Naguibneva I., Fritsch L., Duquet A., Ait-Si-Ali S., Robin P., Vervisch A., Pritchard L.L., Cole P., and Harel-Bellan A. CBP/p300 and muscle differentiation: no HAT, no muscle. EMBO J. 20 (2001) 6816-6825
-
(2001)
EMBO J.
, vol.20
, pp. 6816-6825
-
-
Polesskaya, A.1
Naguibneva, I.2
Fritsch, L.3
Duquet, A.4
Ait-Si-Ali, S.5
Robin, P.6
Vervisch, A.7
Pritchard, L.L.8
Cole, P.9
Harel-Bellan, A.10
-
102
-
-
0030938916
-
The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B
-
Datto M.B., Hu P.P., Kowalik T.F., Yingling J., and Wang X.F. The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B. Mol. Cell. Biol. 17 (1997) 2030-2037
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2030-2037
-
-
Datto, M.B.1
Hu, P.P.2
Kowalik, T.F.3
Yingling, J.4
Wang, X.F.5
-
103
-
-
0029020945
-
Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation
-
Missero C., Calautti E., Eckner R., Chin J., Tsai L.H., Livingston D.M., and Dotto G.P. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 5451-5455
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5451-5455
-
-
Missero, C.1
Calautti, E.2
Eckner, R.3
Chin, J.4
Tsai, L.H.5
Livingston, D.M.6
Dotto, G.P.7
-
104
-
-
2142776283
-
The acetyltransferase activity of CBP stimulates transcription
-
Martinez-Balbás M.A., Bannister A.J., Martin K., Haus-Seuffert P., Meisterernst M., and Kouzarides T. The acetyltransferase activity of CBP stimulates transcription. EMBO J. 17 (1998) 2886-2893
-
(1998)
EMBO J.
, vol.17
, pp. 2886-2893
-
-
Martinez-Balbás, M.A.1
Bannister, A.J.2
Martin, K.3
Haus-Seuffert, P.4
Meisterernst, M.5
Kouzarides, T.6
-
105
-
-
0030967951
-
RNA helicase A mediates association of CBP with RNA polymerase II
-
Nakajima T., Uchida C., Anderson S.F., Lee C.G., Hurwitz J., Parvin J.D., and Montminy M. RNA helicase A mediates association of CBP with RNA polymerase II. Cell 90 (1997) 1107-1112
-
(1997)
Cell
, vol.90
, pp. 1107-1112
-
-
Nakajima, T.1
Uchida, C.2
Anderson, S.F.3
Lee, C.G.4
Hurwitz, J.5
Parvin, J.D.6
Montminy, M.7
-
106
-
-
22344436360
-
p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
-
Devgan V., Mammucari C., Millar S.E., Brisken C., and Dotto G.P. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 19 (2005) 1485-1495
-
(2005)
Genes Dev.
, vol.19
, pp. 1485-1495
-
-
Devgan, V.1
Mammucari, C.2
Millar, S.E.3
Brisken, C.4
Dotto, G.P.5
-
107
-
-
0038682913
-
Induction of transcription through the CRD1 motif by p21WAF1/CIP1 is core promoter specific and cyclin dependent kinase independent
-
Gregory D.J., Garcia-Wilson E., Poole J.C., Snowden A.W., Roninson I.B., and Perkins N.D. Induction of transcription through the CRD1 motif by p21WAF1/CIP1 is core promoter specific and cyclin dependent kinase independent. Cell Cycle 1 (2002) 343-350
-
(2002)
Cell Cycle
, vol.1
, pp. 343-350
-
-
Gregory, D.J.1
Garcia-Wilson, E.2
Poole, J.C.3
Snowden, A.W.4
Roninson, I.B.5
Perkins, N.D.6
-
108
-
-
63149121093
-
p21(WAF1) negatively regulates DNMT1 expression in mammalian cells
-
Tan H.H., and Porter A.G. p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. Biochem. Biophys. Res. Commun. 382 (2009) 171-176
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.382
, pp. 171-176
-
-
Tan, H.H.1
Porter, A.G.2
-
109
-
-
41149125554
-
Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair
-
Cazzalini O., Perucca P., Savio M., Necchi D., Bianchi L., Stivala L.A., Ducommun B., Scovassi A.I., and Prosperi E. Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair. Nucleic Acids Res. 36 (2008) 1713-1722
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 1713-1722
-
-
Cazzalini, O.1
Perucca, P.2
Savio, M.3
Necchi, D.4
Bianchi, L.5
Stivala, L.A.6
Ducommun, B.7
Scovassi, A.I.8
Prosperi, E.9
-
110
-
-
0037450761
-
p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage
-
Rubbi C.P., and Milner J. p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage. EMBO J. 22 (2003) 975-986
-
(2003)
EMBO J.
, vol.22
, pp. 975-986
-
-
Rubbi, C.P.1
Milner, J.2
-
111
-
-
0242582360
-
The human proliferating cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression
-
Hong R., and Chakravarti D. The human proliferating cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression. J. Biol. Chem. 278 (2003) 44505-44513
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44505-44513
-
-
Hong, R.1
Chakravarti, D.2
-
112
-
-
0034635914
-
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases
-
Chang B.D., Watanabe K., Broude E.V., Fang J., Poole J.C., Kalinichenko T.V., and Roninson I.B. Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 4291-4296
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 4291-4296
-
-
Chang, B.D.1
Watanabe, K.2
Broude, E.V.3
Fang, J.4
Poole, J.C.5
Kalinichenko, T.V.6
Roninson, I.B.7
-
113
-
-
13144256711
-
Induction of transcription by p21Waf1/Cip1/Sdi1: role of NFkappaB and effect of non-steroidal anti-inflammatory drugs
-
Poole J.C., Thain A., Perkins N.D., and Roninson I.B. Induction of transcription by p21Waf1/Cip1/Sdi1: role of NFkappaB and effect of non-steroidal anti-inflammatory drugs. Cell Cycle 3 (2004) 931-940
-
(2004)
Cell Cycle
, vol.3
, pp. 931-940
-
-
Poole, J.C.1
Thain, A.2
Perkins, N.D.3
Roninson, I.B.4
-
114
-
-
0029102829
-
Inhibition of nucleotide excision repair by cyclin-dependent kinase inhibitor p21
-
Pan Z.-Q., Reardon J.T., Li L., Flores-Rozas H., Legerski R., Sancar A., and Hurwitz J. Inhibition of nucleotide excision repair by cyclin-dependent kinase inhibitor p21. J. Biol. Chem. 270 (1995) 22008-22016
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22008-22016
-
-
Pan, Z.-Q.1
Reardon, J.T.2
Li, L.3
Flores-Rozas, H.4
Legerski, R.5
Sancar, A.6
Hurwitz, J.7
-
115
-
-
0029016275
-
Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21
-
Podust V.N., Podust L., Goubin F., Ducommun B., and Hübscher H. Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21. Biochemistry 34 (1995) 8869-8875
-
(1995)
Biochemistry
, vol.34
, pp. 8869-8875
-
-
Podust, V.N.1
Podust, L.2
Goubin, F.3
Ducommun, B.4
Hübscher, H.5
-
116
-
-
0032864677
-
The C-terminal domain of p21 inhibits nucleotide excision repair in vitro and in vivo
-
Cooper M.P., Balajee A.S., and Bohr V.A. The C-terminal domain of p21 inhibits nucleotide excision repair in vitro and in vivo. Mol. Biol. Cell 10 (1999) 2119-2129
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 2119-2129
-
-
Cooper, M.P.1
Balajee, A.S.2
Bohr, V.A.3
-
117
-
-
0034053780
-
p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes
-
Smith L., Ford J.M., Hollander M.C., Bortnick R.A., Amounson S.A., Seo Y.R., Deng C., Hanawalt P.C., and Fornace A.J. p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Mol. Cell. Biol. 20 (2000) 3705-3714
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3705-3714
-
-
Smith, L.1
Ford, J.M.2
Hollander, M.C.3
Bortnick, R.A.4
Amounson, S.A.5
Seo, Y.R.6
Deng, C.7
Hanawalt, P.C.8
Fornace, A.J.9
-
118
-
-
0035854825
-
The p53 regulated cyclin-dependent kinase inhibitor, p21 (cip1,waf1,sdi1), is not required for global genomic and transcriptional coupled nucleotide excision repair of UV-induced DNA photoproducts
-
Adimoolam S., Lin C.X., and Ford J.M. The p53 regulated cyclin-dependent kinase inhibitor, p21 (cip1,waf1,sdi1), is not required for global genomic and transcriptional coupled nucleotide excision repair of UV-induced DNA photoproducts. J. Biol. Chem. 28 (2001) 25813-25822
-
(2001)
J. Biol. Chem.
, vol.28
, pp. 25813-25822
-
-
Adimoolam, S.1
Lin, C.X.2
Ford, J.M.3
-
119
-
-
0035328786
-
Ablation of p21waf1cip1 expression enhances the capacity of p53-deficient human tumor cells to repair UVB-induced DNA damage
-
Therrien J.P., Loignon M., Drouin R., and Drobetsky E.A. Ablation of p21waf1cip1 expression enhances the capacity of p53-deficient human tumor cells to repair UVB-induced DNA damage. Cancer Res. 61 (2001) 3781-3786
-
(2001)
Cancer Res.
, vol.61
, pp. 3781-3786
-
-
Therrien, J.P.1
Loignon, M.2
Drouin, R.3
Drobetsky, E.A.4
-
120
-
-
0036204535
-
waf/cip1 expression exhibit normal nucleotide excision repair of UV-induced DNA damage
-
waf/cip1 expression exhibit normal nucleotide excision repair of UV-induced DNA damage. Carcinogenesis 3 (2002) 403-410
-
(2002)
Carcinogenesis
, vol.3
, pp. 403-410
-
-
Wani, M.A.1
Wani, G.2
Yao, J.3
Zhu, Q.4
Wani, A.5
-
121
-
-
0028675510
-
Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision repair
-
Shivji M.K.K., Grey S.J., Strausfeld U.P., Wood R.D., and Blow J.J. Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision repair. Curr. Biol. 4 (1994) 1062-1068
-
(1994)
Curr. Biol.
, vol.4
, pp. 1062-1068
-
-
Shivji, M.K.K.1
Grey, S.J.2
Strausfeld, U.P.3
Wood, R.D.4
Blow, J.J.5
-
122
-
-
0032481128
-
Resistance of human nucleotide excision repair synthesis in vitro to p21CDKN1
-
Shivji M.K.K., Ferrari E., Ball K., Hübscher U., and Wood R.D. Resistance of human nucleotide excision repair synthesis in vitro to p21CDKN1. Oncogene 17 (1998) 2827-2838
-
(1998)
Oncogene
, vol.17
, pp. 2827-2838
-
-
Shivji, M.K.K.1
Ferrari, E.2
Ball, K.3
Hübscher, U.4
Wood, R.D.5
-
124
-
-
0030612714
-
Role of p21waf/cip1/sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells
-
Sheikh M.S., Chen Y.Q., Smith M.L., and Fornace Jr. A.J. Role of p21waf/cip1/sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells. Oncogene 14 (1997) 1875-1882
-
(1997)
Oncogene
, vol.14
, pp. 1875-1882
-
-
Sheikh, M.S.1
Chen, Y.Q.2
Smith, M.L.3
Fornace Jr., A.J.4
-
125
-
-
0030088038
-
Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage
-
Li R., Hannon G.J., Beach D., and Stillman B. Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Curr. Biol. 6 (1996) 189-199
-
(1996)
Curr. Biol.
, vol.6
, pp. 189-199
-
-
Li, R.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
126
-
-
0029661817
-
waf1/cip1 protein associates with the detergent-insoluble form of PCNA concomitantly with disassembly of PCNA at nucleotide excision repair sites
-
waf1/cip1 protein associates with the detergent-insoluble form of PCNA concomitantly with disassembly of PCNA at nucleotide excision repair sites. Oncogene 13 (1996) 1591-1598
-
(1996)
Oncogene
, vol.13
, pp. 1591-1598
-
-
Savio, M.1
Stivala, L.A.2
Scovassi, A.I.3
Bianchi, L.4
Prosperi, E.5
-
127
-
-
0032054738
-
Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin
-
Ruan S., Okcu M.F., Ren J.P., Chiao P., Andreeff M., Levin V., and Zhang W. Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin. Cancer Res. 58 (1998) 1538-1543
-
(1998)
Cancer Res.
, vol.58
, pp. 1538-1543
-
-
Ruan, S.1
Okcu, M.F.2
Ren, J.P.3
Chiao, P.4
Andreeff, M.5
Levin, V.6
Zhang, W.7
-
128
-
-
0035252699
-
waf1/cip1-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites
-
waf1/cip1-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites. Oncogene 20 (2001) 563-570
-
(2001)
Oncogene
, vol.20
, pp. 563-570
-
-
Stivala, L.A.1
Riva, F.2
Cazzalini, O.3
Savio, M.4
Prosperi, E.5
-
129
-
-
0035163025
-
Revisiting the rodent repairadox
-
Hanawalt P.C. Revisiting the rodent repairadox. Environ. Mol. Mutagen. 38 (2001) 89-96
-
(2001)
Environ. Mol. Mutagen.
, vol.38
, pp. 89-96
-
-
Hanawalt, P.C.1
-
130
-
-
33646674105
-
CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen
-
CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen. J. Cell Sci. 119 (2006) 1517-1527
-
(2006)
J. Cell Sci.
, vol.119
, pp. 1517-1527
-
-
Perucca, P.1
Cazzalini, O.2
Mortusewicz, O.3
Necchi, D.4
Savio, M.5
Nardo, T.6
Stivala, L.A.7
Leonhardt, H.8
Cardoso, M.C.9
Prosperi, E.10
-
131
-
-
55449119244
-
p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
-
Soria G., Speroni J., Podhajcer O.L., Prives C., and Gottifredi V. p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation. J. Cell Sci. 121 (2008) 3271-3282
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3271-3282
-
-
Soria, G.1
Speroni, J.2
Podhajcer, O.L.3
Prives, C.4
Gottifredi, V.5
-
132
-
-
70450285163
-
WAF1/CIP1 protein prior to its cytosolic degradation by UV enhances DNA repair and survival
-
WAF1/CIP1 protein prior to its cytosolic degradation by UV enhances DNA repair and survival. Biochem. Biophys. Res. Commun. 390 (2009) 1361-1366
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 1361-1366
-
-
Lee, J.Y.1
Kim, H.K.2
Kim, J.Y.3
Sohn, J.4
-
133
-
-
38049000832
-
Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step
-
Mocquet V., Lainé J.P., Riedl T., Yajin Z., Lee M.Y., and Egly J.M. Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step. EMBO J. 27 (2007) 155-167
-
(2007)
EMBO J.
, vol.27
, pp. 155-167
-
-
Mocquet, V.1
Lainé, J.P.2
Riedl, T.3
Yajin, Z.4
Lee, M.Y.5
Egly, J.M.6
-
134
-
-
0036153467
-
Characterization of CDKN1A (p21) binding to sites of heavy-ion-induced damage: colocalization with proteins involved in DNA repair
-
Jakob B., Scholz M., and Taucher-Scholz G. Characterization of CDKN1A (p21) binding to sites of heavy-ion-induced damage: colocalization with proteins involved in DNA repair. Int. J. Radiat. Biol. 78 (2002) 75-88
-
(2002)
Int. J. Radiat. Biol.
, vol.78
, pp. 75-88
-
-
Jakob, B.1
Scholz, M.2
Taucher-Scholz, G.3
-
135
-
-
0035869074
-
Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis
-
Hasan S., Hassa P.O., Imhof R., and Hottiger M.O. Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis. Nature 410 (2001) 387-391
-
(2001)
Nature
, vol.410
, pp. 387-391
-
-
Hasan, S.1
Hassa, P.O.2
Imhof, R.3
Hottiger, M.O.4
-
136
-
-
33646146161
-
p53 and p21 regulate error-prone DNA repair to yield a lower mutation load
-
Avkin S., Sevilya Z., Toube L., Geacintov N., Chaney S.G., Oren M., and Livneh Z. p53 and p21 regulate error-prone DNA repair to yield a lower mutation load. Mol. Cell 22 (2006) 407-413
-
(2006)
Mol. Cell
, vol.22
, pp. 407-413
-
-
Avkin, S.1
Sevilya, Z.2
Toube, L.3
Geacintov, N.4
Chaney, S.G.5
Oren, M.6
Livneh, Z.7
-
137
-
-
58049215354
-
The p21 and PCNA partnership. A new twist for an old plot
-
Prives C., and Gottifredi V. The p21 and PCNA partnership. A new twist for an old plot. Cell Cycle 7 (2008) 3840-3846
-
(2008)
Cell Cycle
, vol.7
, pp. 3840-3846
-
-
Prives, C.1
Gottifredi, V.2
-
138
-
-
33646156444
-
Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation
-
Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation. Oncogene 25 (2006) 2829-2838
-
(2006)
Oncogene
, vol.25
, pp. 2829-2838
-
-
Soria, G.1
Podhajcer, O.2
Prives, C.3
Gottifredi, V.4
-
139
-
-
0035966081
-
Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair
-
Tom S., Ranalli T.A., Podust V.N., and Bambara R.A. Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair. J. Biol. Chem. 276 (2001) 48781-48789
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48781-48789
-
-
Tom, S.1
Ranalli, T.A.2
Podust, V.N.3
Bambara, R.A.4
-
140
-
-
0141960298
-
waf1/cip1. A dynamic exchange of partners
-
waf1/cip1. A dynamic exchange of partners. J. Biol. Chem. 278 (2003) 39265-39268
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39265-39268
-
-
Frouin, I.1
Maga, G.2
Denegri, M.3
Riva, F.4
Savio, M.5
Spadari, S.6
Prosperi, E.7
Scovassi, A.I.8
-
141
-
-
0141429168
-
WAF1 to promote DNA repair
-
WAF1 to promote DNA repair. Cell 114 (2003) 599-610
-
(2003)
Cell
, vol.114
, pp. 599-610
-
-
Bendjennat, M.1
Boulaire, J.2
Jascur, T.3
Brickner, H.4
Barbier, V.5
Sarasin, A.6
Fotedar, A.7
Fotedar, R.8
-
145
-
-
0141987892
-
Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation
-
Bloom J., Amador V., Bartolini F., DeMartino G., and Pagano M. Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation. Cell 115 (2003) 71-82
-
(2003)
Cell
, vol.115
, pp. 71-82
-
-
Bloom, J.1
Amador, V.2
Bartolini, F.3
DeMartino, G.4
Pagano, M.5
-
146
-
-
0038219632
-
Waf1/Cip1 protein stability via cyclin-D1-imposed block in proteasome-mediated degradation
-
Waf1/Cip1 protein stability via cyclin-D1-imposed block in proteasome-mediated degradation. EMBO J. 22 (2003) 2036-2046
-
(2003)
EMBO J.
, vol.22
, pp. 2036-2046
-
-
Coleman, M.L.1
Marshall, C.J.2
Olson, M.F.3
-
148
-
-
1942437554
-
MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53
-
Zhang Z., Wang H., Li M., Agrawal S., Chen X., and Zhang R. MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53. J. Biol. Chem. 279 (2004) 16000-16006
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16000-16006
-
-
Zhang, Z.1
Wang, H.2
Li, M.3
Agrawal, S.4
Chen, X.5
Zhang, R.6
-
149
-
-
33748753391
-
UV induces p21 rapid turnover independently of ubiquitin and Skp2
-
Lee H., Zeng S.X., and Lu H. UV induces p21 rapid turnover independently of ubiquitin and Skp2. J. Biol. Chem. 281 (2006) 26876-26883
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26876-26883
-
-
Lee, H.1
Zeng, S.X.2
Lu, H.3
-
155
-
-
0032511893
-
Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21
-
Cayrol C., and Ducommun B. Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21. Oncogene 17 (1998) 2437-2444
-
(1998)
Oncogene
, vol.17
, pp. 2437-2444
-
-
Cayrol, C.1
Ducommun, B.2
-
156
-
-
65649105790
-
Cul4A abrogation augments DNA damage response and protection against skin carcinogenesis
-
Liu L., Lee S., Zhang J., Peters S.B., Hannah J., Zhang Y., Yin Y., Koff A., Ma L., and Zhou P. Cul4A abrogation augments DNA damage response and protection against skin carcinogenesis. Mol. Cell 34 (2009) 451-460
-
(2009)
Mol. Cell
, vol.34
, pp. 451-460
-
-
Liu, L.1
Lee, S.2
Zhang, J.3
Peters, S.B.4
Hannah, J.5
Zhang, Y.6
Yin, Y.7
Koff, A.8
Ma, L.9
Zhou, P.10
-
157
-
-
0032490853
-
waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis
-
waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis. Oncogene 17 (1998) 545-555
-
(1998)
Oncogene
, vol.17
, pp. 545-555
-
-
McKay, B.C.1
Ljungman, M.2
Rainbow, A.J.3
-
158
-
-
27844452053
-
CDKN1A in cells surviving UV-irradiation
-
CDKN1A in cells surviving UV-irradiation. DNA Repair 4 (2005) 1457-1462
-
(2005)
DNA Repair
, vol.4
, pp. 1457-1462
-
-
Itoh, T.1
Linn, S.2
-
159
-
-
67649774566
-
DDB2 decides cell fate following DNA damage
-
Stoyanova T., Roy N., Kopanja D., Bagchi S., and Raychaudhuri P. DDB2 decides cell fate following DNA damage. Proc. Natl. Acad. Sci. U.S.A. 106 (2009) 10690-10695
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 10690-10695
-
-
Stoyanova, T.1
Roy, N.2
Kopanja, D.3
Bagchi, S.4
Raychaudhuri, P.5
-
161
-
-
77952565848
-
p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase 1
-
O. Cazzalini, F. Donà, M. Savio, M. Tillhon, C. Maccario, P. Perucca, L.A. Stivala, A.I. Scovassi, E., Prosperi, p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase 1. DNA Repair.
-
DNA Repair
-
-
Cazzalini, O.1
Donà, F.2
Savio, M.3
Tillhon, M.4
Maccario, C.5
Perucca, P.6
Stivala, L.A.7
Scovassi, A.I.8
Prosperi, E.9
|