Osteoblasts survive the arsenic trioxide treatment by activation of ATM-mediated pathway

Biochemical Pharmacology

Volumn 85, Issue 7, 2013, Pages 1018-1026

  Hu, Yu Chen ^a   Hsieh, Bau Shan ^a   Cheng, Hsiao Ling ^a   Huang, Li Wen ^b   Huang, Tzu Ching ^a   Huang, I Yu ^c   Chang, Kee Lung ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Arsenic trioxide; ATM; Cell cycle; Checkpoint kinase; Osteoblast

Indexed keywords

ARSENIC TRIOXIDE; ATM PROTEIN; CASPASE 3; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; HISTONE H2AX; PROTEIN BAX; PROTEIN P21; PROTEIN P53; SINGLE STRANDED DNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; DNA REPLICATION; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; OSTEOBLAST; OSTEOSARCOMA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; ARSENICALS; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASES; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; OSTEOBLASTS; OXIDES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84874661208     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.01.008     Document Type: Article

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