P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Yao, Hongwei ^a   Sundar, Isaac K ^a   Gorbunova, Vera ^b   Rahman, Irfan ^a  

^a Lung Biology and Disease Program ^*  (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOBENZAMIDE; BETA GALACTOSIDASE; CIGARETTE SMOKE; CYCLINE; DNA; HISTONE H2AX; KU ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN P21;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGING; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; ENZYME ACTIVITY; GENE DELETION; LUNG INJURY; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, NUCLEAR; BENZAMIDES; BETA-GALACTOSIDASE; CELL AGING; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA-BINDING PROTEINS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HISTONES; LUNG; MICE; MICE, KNOCKOUT; P21-ACTIVATED KINASES; POLY(ADP-RIBOSE) POLYMERASES; PROLIFERATING CELL NUCLEAR ANTIGEN; SIGNAL TRANSDUCTION; SMOKING;

EID: 84893193039     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080007     Document Type: Article

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