Copper ability to induce premature senescence in human fibroblasts

Age

Volumn 34, Issue 4, 2012, Pages 783-794

  Matos, Liliana ^a,b,c   Gouveia, Alexandra ^a,b,c   Almeida, Henrique ^b,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b University of Porto   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

Ageing; Cellular senescence; Copper; Human fibroblasts; Metals; Oxidative stress

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; CLUSTERIN; COPPER; COPPER SULFATE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; FIBRONECTIN; HEME OXYGENASE 1; MESSENGER RNA; PROTEIN P21; SOMATOMEDIN BINDING PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CELL AGING; CELL ENLARGEMENT; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CLUSTERIN GENE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYCLIN DEPENDENT KINASE INHIBITOR 1A GENE; CYTOTOXICITY TEST; ENZYME ACTIVITY; FIBROBLAST; FIBRONECTIN GENE; G1 PHASE CELL CYCLE CHECKPOINT; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC ASSOCIATION; HEME OXYGENASE 1 GENE; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; MOLECULAR DYNAMICS; OXIDATIVE STRESS; P21 GENE; PROTEIN CONTENT; PROTEIN EXPRESSION; SOMATOMEDIN BINDING PROTEIN 3 GENE; TRANSFORMING GROWTH FACTOR BETA1 GENE; WESTERN BLOTTING;

BETA-GALACTOSIDASE; BLOTTING, WESTERN; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CLUSTERIN; COPPER SULFATE; FIBROBLASTS; HUMANS; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; REFERENCE VALUES; RNA, MESSENGER; SAMPLING STUDIES; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 84866491060     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9276-7     Document Type: Article

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