The role of metals in site-specific DNA damage with reference to carcinogenesis

Free Radical Biology and Medicine

Volumn 32, Issue 9, 2002, Pages 822-832

  Kawanishi, Shosuke ^a   Hiraku, Yusuke ^a   Murata, Mariko ^a   Oikawa, Shinji ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Carcinogenesis; DNA damage; Free radicals; Metal; Reactive oxygen species; Site specificity

Indexed keywords

4 BIPHENYLAMINE; BENZENE DERIVATIVE; CAFFEIC ACID; CHROMIUM DERIVATIVE; COBALT; COPPER; HETEROCYCLIC AMINE; HYDROGEN PEROXIDE; IRON; METAL; NICKEL; NITRILOTRIACETATE IRON; NITROSO DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TOLUIDINE DERIVATIVE;

CARCINOGENESIS; CARCINOGENICITY; CATALYSIS; DNA ADDUCT; DNA DAMAGE; HUMAN; INFLAMMATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW;

EID: 0036569447     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00779-7     Document Type: Article

References (110)

1. Mechanism of DNA cleavage induced by sodium chromate(VI) in the presence of hydrogen peroxide
2. Hydroxy radical production human DNA damage induced by ferric nitrilotriacetate hydrogen peroxide
3. Site-specific DNA damage induced by cobalt(II) ion and hydrogen peroxide: Role of singlet oxygen
4. Site-specific DNA damage induced by nickel(II) ion in the presence of hydrogen peroxide
5. ESR evidence for superoxide, hydroxyl radicals, and singlet oxygen produced from hydrogen peroxide and nickel(II) complex of gylcylgylcyl-L-histidine
6. Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum-nitrilotriacetate complexes in rats
7. Carcinogenicity of metal compounds: Possible role of DNA repair inhibition
8. Thiol involvement in the inhibition of DNA repair by metals in mammalian cells
9. Epidemiological and experimental aspects of metal carcinogenesis: Physicochemical properties, kinetics, and the active species
10. Inhibition of 8-hydroxyguanine repair in testes after administration of cadmium chloride to GSH-depleted rats
11. Mechanism of oxidative DNA damage induced by δ-aminolevulinic acid in the presence of copper ion
12. Oxidative DNA damage in cultured cells and rat lungs by carcinogenic nickel compounds
13. Possible role of oxidative damage in metal-induced carcinogenesis
14. Carcinogen-mediated oxidant formation and oxidative DNA damage
15. Chromium and chromium compounds
16. Sequencing end-labeled DNA with base-specific chemical cleavages
17. Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue
18. Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: Similar reactivity toward single- and double-stranded forms
19. Site-specific DNA damage induced by UVA radiation in the presence of endogenous photosensitizer
20. The formation of DNA cleaving species during the reduction of chromate by ascorbate
21. The formation of both apurinic/apyrimidinic sites and single-strand breaks by chromate and glutathione arises from attack by the same single reactive species and is dependent on molecular oxygen
22. DNA fragmentation, DNA-protein crosslinks, postlabeled nucleotidic modifications, and 8-hydroxy-2′-deoxyguanosine in the lung but not in the liver of rats receiving intratracheal instillations of chromium(VI). Chemoprevention by oral N-acetylcysteine
23. Body iron stores and the risk of cancer
24. Hydroxyl radical production and human DNA damage induced by ferric nitrilotriacetate and hydrogen peroxide
25. Urinary excretion of biomarkers of oxidative kidney damage induced by ferric nitrilotriacetate
26. Iron-induced oxidative DNA damage and its repair in primary rat hepatocyte culture
27. High incidence of allelic loss on chromosome 5 and inactivation of p15INK4B and p16INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats
28. Cobalt and cobalt compounds
29. 2 in the presence of chelators in relation to DNA damage and 2′-deoxyguanosine hydroxylation
30. 2 in rat neuronal PC12 cells
31. Nickel and nickel compounds
32. Chronic infections and inflammatory processes as cancer risk factors: Possible role of chronically elevated nitric oxide in carcinogenesis
33. Potential genotoxicity of chronically elevated nitric oxide: A review
34. Damage to DNA by reactive oxygen and nitrogen species: Role in inflammatory disease and progression to cancer
35. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
36. Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase
37. Structural integrity of the nuclear matrix: Differential effects of thiol agents and metal chelators
38. Effects of ionic strength on endogenous nuclease activity in chelated and nonchelated chromatin
39. Interaction of mercury and copper with constitutive heterochromatin and euchromatin in Vivo and in Vitro
40. Abnormal copper accumulation in non-cancerous and cancerous liver tissues of LEC rats developing hereditary hepatitis and spontaneous hepatoma
41. Copper in human mammary carcinogenesis: A case-cohort study
42. Copper and genomic stability in mammals
43. Hydroxyl free radical is not the main active species in site-specific DNA damage induced by copper (II) ion and hydrogen peroxide
44. 2-induced DNA damage and alter its site specificity
45. Binding and the nature of Cu(II) ion interaction with nucleosomes
46. 2-induced DNA damage is enhanced by packaging of DNA as a nucleosome
47. Iron and its sensitive balance in the cell
48. Haematite and ferric oxide
49. Role of iron and superoxide for generation of hydroxyl radical, oxidative DNA lesions, and mutagenesis in Escherichia coli
50. Some industrial chemicals and dyestuffs
51. Benzene
52. The toxicity of benzene and its metabolism and molecular pathology in human risk assessment
53. Human DNA damage induced by 1,2,4-benzenetriol, a benzene metabolite
54. Site specificity and mechanism of oxidative DNA damage induced by carcinogenic catechol
55. Oxidative DNA damage and apoptosis induced by benzene metabolites
56. Ferritin stimulation of hydroxy radical production by rat liver nuclei
57. Site-specific DNA damage induced by NADH in the presence of copper(II): Role of active oxygen species
58. Biochemistry of redox reactions
59. Copper-mediated DNA damage by metabolites of p-dichlorobenzene
60. Role of active oxygen species in DNA damage by pentachlorophenol metabolites
61. DNA damage induced by metabolites of o-phenylphenol in the presence of copper(II) ion
62. Oxidative damage to cellular and isolated DNA by metabolites of a fungicide ortho-phenylphenol
63. Oxidative DNA damage by minor metabolites of toluene may lead to carcinogenesis and reproductive dysfunction
64. Oxidative DNA damage and apoptosis induced by metabolites of butylated hydroxytoluene
65. 2 formation
66. Oxidative DNA damage induced by homogentisic acid, a tyrosine metabolite
67. Ortho-Toluidine
68. 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation
69. Biomonitoring of urinary aromatic amines and arylamine hemoglobin adducts in exposed workers and nonexposed control persons
70. Species differences in the covalent binding of p-chloro-o-toluidine to DNA
71. Organ-specific genotoxicity of the potent rodent bladder carcinogens o-anisidine and p-cresidine
72. A flow cytometric analysis of cytotoxic effects of nitrobenzene on rat spermatogenesis
73. Oxidative DNA damage by a metabolite of carcinogenic and reproductive toxic nitrobenzene in the presence of NADH and Cu(II)
74. Distinct mechanisms of oxidative DNA damage by two metabolites of carcinogenic o-toluidine
75. Oxidative DNA damage induced by a metabolite of carcinogenic o-anisidine: Enhancement of DNA damage and alteration in its sequence-specificity by superoxide dismutase
76. 4-Aminobiphenyl
77. Tobacco habits other than smoking; Betel-quid and areca nut chewing; And some related nitrosamines
78. Reductive metabolism of 4-nitrobiphenyl by rat liver fraction
79. Mutagenicity of 4-aminobiphenyl and 4-acetylaminobiphenyl in Salmonella typhimurium strains expressing different levels of N-acetyltransferase
80. Mechanism of oxidative DNA damage induced by carcinogenic 4-aminobiphenyl
81. Non-enzymatic reduction of nitro-derivative of a heterocyclic amine IQ by NADH and Cu(II) leads to oxidative DNA damage
82. Mechanism of oxidative DNA damage induced by a heterocyclic amine, 2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline
83. Solvent in pesticides
84. Subchronic inhalation toxicity of nitromethane and 2-nitropropane
85. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane
86. Mechanism of metal-mediated DNA damage induced by metabolites of carcinogenic 2-nitropropane
87. Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound
88. Site-specific oxidation at GG and GGG sequences in double-stranded DNA by benzoyl peroxide as a tumor promoter
89. Theoretical studies of GG-specific photocleavage of DNA via electron transfer: Significant lowering of ionization potential and 5′-localization of HOMO of stacked GG bases in B-form DNA
90. High production of catalase in hydrogen peroxide-resistant human leukemia HL-60 cell lines
91. Benzoyl peroxide-induced damage to DNA and its components: Direct evidence for the generation of base adducts, sugar radicals, and strand breaks
92. Catechol estrogen conjugates and DNA adducts in the kidney of male Syrian golden hamsters treated with 4-hydroxyestradiol: Potential biomarkers for estrogen-initiated cancer
93. Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency
94. Oxidative DNA damage: Endogenous and chemically induced
95. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
96. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
97. Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase
98. Excision of 8-oxoguanine within clustered damage by the yeast OGG1 protein
99. The presence of two distinct 8-oxoguanine repair enzymes in human cells: Their potential complementary roles in preventing mutation
100. Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria
101. Excision of products of oxidative DNA base damage by human NTH1 protein
102. Disposition and biological activity of benzo [a]pyrene-7,8-dione. A genotoxic metabolite generated by dihydrodiol dehydrogenase