Accumulation of p21Cip1/WAF1during hyperoxic lung injury in mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 19, Issue 5, 1998, Pages 777-785

  O'Reilly, Michael A ^a,b   Staversky, Rhonda J ^a   Watkins, Richard H ^a   Maniscalco, William M ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CDKN1A PROTEIN, MOUSE; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; OXYGEN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; ARTICLE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HYPEROXIA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG; MALE; MOUSE; MOUSE STRAIN; PATHOLOGY; PATHOPHYSIOLOGY; TIME;

ANIMALS; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; GENE EXPRESSION REGULATION; HYPEROXIA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG; MALE; MICE; MICE, INBRED STRAINS; MICROTUBULE-ASSOCIATED PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; OXYGEN; RNA, MESSENGER; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0032209550     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.19.5.3200     Document Type: Article

References (36)

1. Crapo, J. D. 1986. Morphologic changes in pulmonary oxygen toxicity. Annu. Rev. Physiol. 48:721-731.
2. Miller, F. J., J. H. Overton, R. Jaskot, and D. B. Menzel. 1985. A model of the regional uptake of gaseous pollutants of the lung: I. The sensitivity of the uptake of ozone in the human lung to lower respiratory tract secretions and exercise. Toxicol. Appl. Pharmacol. 79:11-27.
3. O'Brodovich, H. M., and R. B. Mellins. 1985. Bronchopulmonary dysplasia: unresolved neonatal acute lung injury. Am. Rev. Respir. Dis. 132: 694-709.
4. Adamson, I. Y., D. H. Bowden, and J. P. Wyatt. 1970. Oxygen poisoning in mice: ultrastructural and surfactant studies during exposure and recovery. Archives of Pathology 90:463-472.
5. Joenje, H. 1989. Genetic toxicology of oxygen. Mutat. Res. 219:193-208.
6. Michiels, C., M. Raes, O. Toussaint, and J. Remacle. 1994. Importance of SE-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic. Biol. Med. 17:235-248.
7. Siede, W. 1995. Cell cycle arrest in response to DNA damage: lessons from yeast. Mutat. Res. 337:73-84.
8. El-Deiry, W. S., T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons, J. M. Trent, D. Lin, W. E. Mercer, K. W. Kinzler, and B. Vogelstein. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
9. Cip1/WAF1 and mediates G1 and S phase checkpoints. Oncogene 12:1387-1396.
10. El-Deiry, W. S., J. W. Harper, P. M. O'Connor, V. E. Velculescu, C. E. Canman, J. Jackman, J. A. Pietenpol, M. Burrell, D. E. Hill, Y. Wang, K. G. Wiman, W. E. Mercer, M. B. Kastan, K. W. Kohn, S. J. Elledge, K. W. Kinzler, and B. Vogelstein. 1994. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 54:1169-1174.
11. Harper, J. W., G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
12. Xiong, Y., G. J. Hannon, H. Zhang, D. Casso, R. Kobayashi, and D. Beach. 1993. p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704.
13. Waga, S., G. J. Hannon, D. Beach, and B. Stillman. 1994. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369:574-578.
14. WAF1/CIP1 -/-human cancer cells. Cancer Res. 56:2250-2255.
15. Waf1/Cip1/Sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells. Oncogene 14:1875-1882.
16. WAF1/CIP1 in breast epithelial cells. Cancer Res. 55:4520-4524.
17. Wang, J., and K. Walsh. 1996. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science 273:359-361.
18. Reynisdottir, I., K. Polyak, A. Iavarone, and J. Massague. 1995. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev. 9:1831-1845.
19. Datto, M. B., Y. Li, J. F. Panus, D. J. Howe, Y. Xiong, and X.-F. Wang. 1995. Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc. Natl. Acad. Sci. USA 92:5545-5549.
20. waf1/cip1 expression involves a post-transcriptional mechanism and activation of the mitogen-activated kinase pathway. Eur. J. Biochem. 245:730-737.
21. Clement, A., M. Edeas, K. Chadelat, and J. S. Brody. 1992. Inhibition of lung epithelial cell proliferation by hyperoxia. J. Clin. Invest. 90:1812-1818.
22. Bui, K. C., S. Buckley, F. Wu, B. Uhal, I. Joshi, J. Liu, M. Hussain, I. Makhoul, and D. Warburton. 1995. Induction of A- and D-type cyclins and cdc2 kinase activity during recovery from short-term hyperoxic lung injury. Am. J. Physiol. 268(Lung Cell. Mol. Physiol.):L625-L635.
23. Tryka, A. F., H. Witschi, D. G. Gosslee, A. H. McArthur, and N. K. Clapp. 1986. Patterns of cell proliferation during recovery from oxygen injury. Am. Rev. Respir. Dis. 133:1055-1059.
24. Corroyer, S., B. Maitre, V. Cazals, and A. Clement. 1996. Altered regulation of G1 cyclins in oxidant-induced growth arrest of lung alveolar epithelial cells. J. Biol. Chem. 271:25117-25125.
25. O'Reilly, M. A., R. J. Staversky, K. C. Flanders, C. J. Johnston, and J. N. Finkelstein. 1997. Temporal changes in expression of TGF-β isoforms in mouse lung exposed to oxygen. Am. J. Physiol. 272(Lung Cell. Mol. Phys iol.):L60-L67.
26. O'Reilly, M. A., R. J. Staversky, B. R. Stripp, and J. N. Finkelstein. 1998. Exposure to hyperoxia induces p53 expression in mouse lung epithelium. Am. J. Respir. Cell Mol. Biol. 18:43-50.
27. Kazzaz, J. A., J. Xu, T. A. Palaia, L. Mantell, A. M. Fein, and S. Horowitz. 1996. Cellular oxygen toxicity: oxidant injury without apoptosis. J. Biol. Chem. 271:15182-15186.
28. CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684.
29. Maniscalco, W. M., R. H. Watkins, J. N. Finkelstein, and M. H. Campbell. 1995. Vascular endothelial growth factor mRNA increases in alveolar epithelial cells during recovery from oxygen injury. Am. J. Respir. Cell Mol. Biol. 13:377-386.
30. Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
31. Sherr, C. J. 1996. Cancer cell cycles. Science 274:1672-1677.
32. CIP1/WAF1 gene in normal diploid human fibroblasts. Science 277:831-834.
33. Li, R., S. Waga, G. J. Hannon, D. Beach, and B. Stillman. 1994. Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature 371:534-537.
34. WAF1. Science 277:1996-2000.
35. Ward, P. A. 1994. Oxygen radicals, cytokines, adhesion molecules, and lung injury. Environ. Health Perspect. 102:13-16.
36. Maki, C. G., and P. M. Howley. 1997. Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol. Cell. Biol. 17:355-363.