Arsenic exposure through drinking water leads to senescence and alteration of telomere length in humans: A case-control study in West Bengal, India

Molecular Carcinogenesis

Volumn 54, Issue 9, 2015, Pages 800-809

  Chatterjee, Debmita ^a   Bhattacharjee, Pritha ^b   Sau, Tanmoy J ^c   Das, Jayanta K ^d   Sarma, Nilendu ^c   Bandyopadhyay, Apurba K ^a   Roy, Sib Sankar ^a   Giri, Ashok K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b UNIVERSITY OF CALCUTTA   (India)

^c NRS MEDICAL COLLEGE   (India)

^d Westbank Hospital   (India)

Author keywords

Alternative lengthening; Arsenic; Humans; Senescence; Telomere

Indexed keywords

ARSENIC; CELL PROTEIN; DRINKING WATER; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; PROTEIN P21; PROTEIN P53; STROMELYSIN; TERMINAL RESTRICTION FRAGMENT 1 PROTEIN; TERMINAL RESTRICTION FRAGMENT 2 PROTEIN; UNCLASSIFIED DRUG; TELOMERASE; WATER POLLUTANT;

ADULT; ARSENIC POISONING; ARTICLE; CASE CONTROL STUDY; CELL AGING; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FEMALE; HUMAN; INDIA; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SENESCENCE ASSOCIATED SECRETORY PHENOTYPE; SKIN DEFECT; TELOMERE HOMEOSTASIS; URINALYSIS; WATER INTOXICATION; AGING; CARCINOGENESIS; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION; SKIN; SKIN DISEASES; TELOMERE; TOXICITY; WATER POLLUTANT;

ADULT; AGING; ARSENIC; CARCINOGENESIS; CASE-CONTROL STUDIES; DRINKING WATER; FEMALE; HUMANS; INDIA; MALE; MIDDLE AGED; SIGNAL TRANSDUCTION; SKIN; SKIN DISEASES; TELOMERASE; TELOMERE; TUMOR SUPPRESSOR PROTEIN P53; WATER POLLUTANTS, CHEMICAL;

EID: 84938958244     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22150     Document Type: Article

References (41)

1. Mondal D, Banerjee M, Kundu M, et al. Comparison of drinking water, raw rice and cooking of rice as arsenic exposure routes in three contrasting areas of West Bengal, India. Environ Geochem Health 2010; 32:463-477.
2. Guidelines for Drinking Water Quality. Health criteria and other supporting information 2. Geneva: World Health Organisation; 1996. pp. 940-949.
3. Ghosh P, Banerjee M, De Chaudhuri S, et al. Comparison of health effects between individuals with and without skin lesions in the population exposed to arsenic through drinking water in West Bengal, India. J Expo Sci Environ Epidemiol 2007; 17:215-223.
4. Paul S, Das N, Bhattacharjee P, et al. Arsenic-induced toxicity and carcinogenicity: A two-wave cross-sectional study in arsenicosis individuals in West Bengal, India. J Expo Sci Environ Epidemiol 2013; 23:156-162.
5. Biswas D, Banerjee M, Sen G, et al. Mechanism of erythrocyte death in human population exposed to arsenic through drinking water. Toxicol Appl Pharmacol 2008; 230:57-66.
6. Jasso-Pineda Y, Díaz-Barriga F, Calderón J, et al. DNA damage and decreased DNA repair in peripheral blood mononuclear cells in individuals exposed to arsenic and lead in a mining site. Biol Trace Elem Res 2012; 146:141-149.
7. Valko M, Izakovic M, Mazur M, Rhodes CJ, Telser J. Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem 2004; 266:37-56.
8. Coppé JP, Desprez PY, Krtolica A, Campisi J. The senescence-associated secretory phenotype: The dark side of tumor suppression. Annu Rev Pathol 2010; 5:99-118.
9. Campisi J, Kim SH, Lim CS, Rubio M. Cellular senescence, cancer and aging: The telomere connection. Exp Gerontol 2001; 36:1619-1637.
10. Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 1995; 92:9363-9367.
11. Karlseder J, Smogorzewska A, de Lange T. Senescence induced by altered telomere state, not telomere loss. Science 2002; 295:2446-2449.
12. Calado RT, Cooper JN, Padilla-Nash HM, et al. Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia. Leukemia 2012; 26:700-707.
13. Zhang TC, Schmitt MT, Mumford JL, et al. Effects of arsenic on telomerase and telomeres in relation to cell proliferation and apoptosis in human keratinocytes and leukemia cells in vitro. Carcinogenesis 2003; 24:1811-1817.
14. Gramatges MM, Telli ML, Balise R, Ford JM. Longer relative telomere length in blood from women with sporadic and familial breast cancer compared with healthy controls. Cancer Epidemiol Biomarkers Prev 2010; 19:605-613.
15. Anic GM, Sondak VK, Messina JL. Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma. Cancer Epidemiol 2013; 37:434-439.
16. Neumann AA, Reddel RR. Telomere maintenance and cancer-Look, no telomerase. Nat Rev Cancer 2002; 2:879-884.
17. Nabetani A, Ishikawa F. Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells. J Biochem 2011; 149:5-14.
18. Bhattacharyya S, Sandy A, Groden J. Unwinding protein complexes in ALTernative telomere maintenance. J Cell Biochem 2010; 109:7-15.
19. Lantuejoul S, Raynaud C, Salameire D, et al. Telomere maintenance and DNA damage responses during lung carcinogenesis. Clin Cancer Res 2010; 16:2979-2988.
20. Dong W, Shen R, Wang Q, et al. Sp1 upregulates expression of TRF2 and TRF2 inhibition reduces tumorigenesis in human colorectal carcinoma cells. Cancer Biol Ther 2009; 8:2166-2174.
21. Biroccio A, Rizzo A, Elli R, et al. TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells. Eur J Cancer 2006; 42:1881-1888.
22. West Bengal Public Health Engineering Department (WBPHED). http://www.wbphed.gov.in (April 2012, last updated, October 2012, last accessed).
23. Banerjee N, Paul S, Sau TJ, et al. Epigenetic modifications of DAPK and p16 genes contribute to arsenic-induced skin lesions and nondermatological health effects. Toxicol Sci 2013; 135:300-308.
24. Kuwana T, Mackey MR, Perkins G, et al. Bid, Bax and lipid cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 2002; 111:331-342.
25. Cawthon RM. Telomere length measurement by a novel monochrome multiplex quantitative PCR method. Nucleic Acids Res 2009; 37:e21.
26. Cheng H, Qiu L, Zhang H, et al. Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells. Acta Biochim Biophys Sin 2011; 43:204-209.
27. Martín-Pardillos A, Sosa C, Sorribas V. Arsenic increases Pi-mediated vascular calcification and induces premature senescence in vascular smooth muscle cells. Toxicol Sci 2013; 131:641-653.
28. Liew CC, Ma J, Tang HC, Zheng R, Dempsey AA. The peripheral blood transcriptome dynamically reflects system wide biology: A potential diagnostic tool. J Lab Clin Med 2006; 147:126-132.
29. Matsushita T, Hasegawa M, Hamaguchi Y, Takehara K, Sato S. Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: Association of interleukin 12 elevation with spontaneous regression of skin sclerosis. J Rheumatol 2006; 33:275-284.
30. Ahmed S, Mahabbat-e Khoda S, Rekha RS, et al. Arsenic-associated oxidative stress, inflammation, and immune disruption in human placenta and cord blood. Environ Health Perspect 2011; 119:258-264.
31. Monickaraj F, Aravind S, Gokulakrishnan K, et al. Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetes. Mol Cell Biochem 2012; 365:343-350.
32. Buchet JP, Lauwerys R, Roels H. Comparison of the urinary excretion of arsenic metabolites after a single dose of sodium arsenite, monomethylarsonate or dimethylarsinate in man. Int Arch Occup Environ Health 1981; 48:71-79.
33. Ferrario D, Collotta A, Carfi M, et al. Arsenic induces telomerase expression and maintains telomere length in human cord blood cells. Toxicology 2009; 260:132-141.
34. Li H, Engström K, Vahter M, Broberg K. Arsenic exposure through drinking water is associated with longer telomeres in peripheral blood. Chem Res Toxicol 2012; 25:2333-2339.
35. Yu J, Lan J, Wang C, et al. PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells. Cancer Lett 2010; 291:177-186.
36. Zhang Y, Cao EH, Qin JF. Up-regulation of telomere-binding TRF1, TRF2 related to reactive oxygen species induced by As(2)O(3) in MGC-803 cells. Eur J Pharmacol 2005; 516:1-9.
37. Smogorzewska A, van Steensel B, Bianchi A, et al. Control of human telomere length by TRF1 and TRF2. Mol Cell Biol 2000; 20:1659-1668.
38. Jiang WQ, Zhong ZH, Henson JD, Reddel RR. Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference. Oncogene 2007; 26:4635-4647.
39. Chung I, Leonhardt H, Rippe K. De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation. J Cell Sci 2011; 124:3603-3618.
40. Jiang WQ, Zhong ZH, Nguyen A, et al. Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins. J Cell Biol 2009; 185:797-810.
41. Ramirez T, Brocher J, Stopper H, Hock R. Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells. Chromosoma 2008; 117:147-157.