Increased p21CIP1/WAF1 and B cell lymphoma leukemia-xL expression and reduced apoptosis in alveolar macrophages from smokers

American Journal of Respiratory and Critical Care Medicine

Volumn 166, Issue 5, 2002, Pages 724-731

  Tomita, Katsuyuki ^a   Caramori, Gaetano ^a   Lim, Sam ^a   Ito, Kazuhiro ^a   Hanazawa, Toyoyuki ^a   Oates, Timothy ^a   Chiselita, Irena ^a   Jazrawi, Elen ^a   Fan Chung, K ^a   Barnes, Peter J ^a   Adcock, Ian M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Apoptosis; Cigarette smoke; Epithelial cells; Monocytes macrophages; p21CIP1 WAF1

Indexed keywords

B CELL LYMPHOMA LEUKEMIA XL; HYDROGEN PEROXIDE; PROTEIN P21; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; ASTHMA; B CELL LEUKEMIA; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LUNG ALVEOLUS MACROPHAGE; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SMOKING;

ADULT; APOPTOSIS; ASTHMA; BCL-X PROTEIN; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; CASE-CONTROL STUDIES; CELL DIVISION; CELLS, CULTURED; CHRONIC DISEASE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SMOKING; STATISTICS, NONPARAMETRIC;

EID: 0036724480     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.2104010     Document Type: Article

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