Sterigmatocystin-Induced DNA Damage Triggers G2 Arrest via an ATM/p53-Related Pathway in Human Gastric Epithelium GES-1 Cells In Vitro

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Zhang, Donghui ^a   Cui, Yu ^a   Shen, Haitao ^a   Xing, Lingxiao ^a   Cui, Jinfeng ^a   Wang, Juan ^a   Zhang, Xianghong ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CAFFEINE; CARCINOGEN; CHECKPOINT KINASE 2; DNA; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN P53; SMALL INTERFERING RNA; STERIGMATOCYSTIN;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EPITHELIUM CELL; EUKARYOTIC CELL; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOLECULAR MECHANICS; PROTEIN EXPRESSION; STOMACH EPITHELIUM;

APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CAFFEINE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHECKPOINT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPITHELIAL CELLS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE SILENCING; HUMANS; MODELS, BIOLOGICAL; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STERIGMATOCYSTIN; STOMACH; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84877972500     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065044     Document Type: Article

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