Methoxychlor and triclosan stimulates ovarian cancer growth by regulating cell cycle- and apoptosis-related genes via an estrogen receptor-dependent pathway

Environmental Toxicology and Pharmacology

Volumn 37, Issue 3, 2014, Pages 1264-1274

  Kim, Joo Young ^a   Yi, Bo Rim ^a   Go, Ryeo Eun ^a   Hwang, Kyung A ^a   Nam, Ki Hoan ^b   Choi, Kyung Chul ^a  

^a Chungbuk National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Endocrine disrupting chemicals; Estrogen receptors; Methoxychlor; Ovarian cancer; Triclosan

Indexed keywords

CYCLIN D1; ESTROGEN RECEPTOR; METHOXYCHLOR; PROTEIN BAX; PROTEIN P21; TRICLOSAN; BAX PROTEIN, HUMAN; CCND1 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; ENDOCRINE DISRUPTOR;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL CYCLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; GENE CONTROL; GENE FUNCTION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MTT ASSAY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OVARY TUMOR; PHYSIOLOGY; TOXICITY; TUMOR CELL LINE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENDOCRINE DISRUPTORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METHOXYCHLOR; OVARIAN NEOPLASMS; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TRICLOSAN;

EID: 84900802679     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.04.013     Document Type: Article

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