Nano-titanium dioxide induces genotoxicity and apoptosis in human lung cancer cell line, A549

Human and Experimental Toxicology

Volumn 32, Issue 2, 2013, Pages 153-166

  Srivastava, R K ^a,b   Rahman, Q ^c   Kashyap, M P ^a,b   Singh, A K ^a,b   Jain, G ^a,b   Jahan, S ^a,b   Lohani, M ^c   Lantow, M ^d   Pant, A B ^a,b  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b NATIONAL CHEMICAL LABORATORY   (India)

^c INTEGRAL UNIVERSITY   (India)

^d UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

A549; apoptosis; genotoxicity; oxidative stress; P53 TiO2 NPs

Indexed keywords

CASPASE 3; CATALASE; GLUTATHIONE; MALONALDEHYDE; MESSENGER RNA; NANOPARTICLE; NANOTITANIUM DIOXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TITANIUM DIOXIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG CANCER; MICRONUCLEUS TEST; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CATALASE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GLUTATHIONE; HUMANS; LIPID PEROXIDATION; MICRONUCLEUS TESTS; MUTAGENS; NANOPARTICLES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TITANIUM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84872311835     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327112462725     Document Type: Article

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