메뉴 건너뛰기




Volumn 38, Issue 4, 2011, Pages 2785-2791

ERK mediates anti-apoptotic effect through phosphorylation and cytoplasmic localization of p21Waf1/Cip1/Sdi in response to DNA damage in normal human embryonic fibroblast (HEF) cells

Author keywords

Apoptosis; Camptothecin; ERK; Etoposide; HEF; P21

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CAMPTOTHECIN; CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P21 WAF1 CIP1 SDI; THREONINE; UNCLASSIFIED DRUG; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

EID: 79960955074     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0423-5     Document Type: Article
Times cited : (15)

References (23)
  • 1
    • 51249090123 scopus 로고    scopus 로고
    • The regulation of extracellular signal-regulated kinase (erk) in mammalian cells
    • Ramos JW (2008) The regulation of extracellular signal-regulated kinase (erk) in mammalian cells. Int J Biochem Cell Biol 40(12):2707-2719
    • (2008) Int J Biochem Cell Biol , vol.40 , Issue.12 , pp. 2707-2719
    • Ramos, J.W.1
  • 2
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • Yoon S, Seger R (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24(1):21-44
    • (2006) Growth Factors , vol.24 , Issue.1 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 3
    • 34547204160 scopus 로고    scopus 로고
    • The mek/erk cascade: From signaling specificity to diverse functions
    • Shaul YD, Seger R (2007) The mek/erk cascade: from signaling specificity to diverse functions. Biochim Biophys Acta 1773(8): 1213-1226
    • (2007) Biochim Biophys Acta , vol.1773 , Issue.8 , pp. 1213-1226
    • Shaul, Y.D.1    Seger, R.2
  • 4
    • 0028880006 scopus 로고
    • Opposing effects of erk and jnk-p38 map kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME (1995) Opposing effects of erk and jnk-p38 map kinases on apoptosis. Science 270(5240):1326-1331
    • (1995) Science , vol.270 , Issue.5240 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 7
    • 24944490193 scopus 로고    scopus 로고
    • The erk cascade: A prototype of mapk signaling
    • Rubinfeld H, Seger R (2005) The erk cascade: a prototype of mapk signaling. Mol Biotechnol 31(2):151-174
    • (2005) Mol Biotechnol , vol.31 , Issue.2 , pp. 151-174
    • Rubinfeld, H.1    Seger, R.2
  • 8
    • 0034881019 scopus 로고    scopus 로고
    • Molecular mechanisms mediating mammalian mitogen-activated protein kinase (mapk) kinase (mek)-mapk cell survival signals
    • Ballif BA, Blenis J (2001) Molecular mechanisms mediating mammalian mitogen-activated protein kinase (mapk) kinase (mek)-mapk cell survival signals. Cell Growth Differ 12(8): 397-408
    • (2001) Cell Growth Differ , vol.12 , Issue.8 , pp. 397-408
    • Ballif, B.A.1    Blenis, J.2
  • 9
    • 0030902111 scopus 로고    scopus 로고
    • P21(waf1/cip1) protects against p53-mediated apoptosis of human melanoma cells
    • Gorospe M, Cirielli C, Wang X, Seth P, Capogrossi MC, Holbrook NJ (1997) P21(waf1/cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene 14(8):929-935
    • (1997) Oncogene , vol.14 , Issue.8 , pp. 929-935
    • Gorospe, M.1    Cirielli, C.2    Wang, X.3    Seth, P.4    Capogrossi, M.C.5    Holbrook, N.J.6
  • 10
    • 0029956387 scopus 로고    scopus 로고
    • Protective role of p21(waf1/cip1) against prostaglandin a2-mediated apoptosis of human colorectal carcinoma cells
    • Gorospe M, Wang X, Guyton KZ, Holbrook NJ (1996) Protective role of p21(waf1/cip1) against prostaglandin a2-mediated apoptosis of human colorectal carcinoma cells. Mol Cell Biol 16(12):6654-6660
    • (1996) Mol Cell Biol , vol.16 , Issue.12 , pp. 6654-6660
    • Gorospe, M.1    Wang, X.2    Guyton, K.Z.3    Holbrook, N.J.4
  • 11
    • 0035821788 scopus 로고    scopus 로고
    • P21 waf1/cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents
    • Mahyar-Roemer M, Roemer K (2001) P21 waf1/cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene 20(26):3387-3398
    • (2001) Oncogene , vol.20 , Issue.26 , pp. 3387-3398
    • Mahyar-Roemer, M.1    Roemer, K.2
  • 12
    • 0033594245 scopus 로고    scopus 로고
    • Induced p21waf expression in h1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin
    • Wang Y, Blandino G, Givol D (1999) Induced p21waf expression in h1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin. Oncogene 18(16):2643-2649
    • (1999) Oncogene , vol.18 , Issue.16 , pp. 2643-2649
    • Wang, Y.1    Blandino, G.2    Givol, D.3
  • 13
    • 71949111129 scopus 로고    scopus 로고
    • Mst kinases monitor actin cytoskeletal integrity and signal via c-jun n-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability
    • Densham RM, O'Neill E, Munro J, Konig I, Anderson K, Kolch W, Olson MF (2009) Mst kinases monitor actin cytoskeletal integrity and signal via c-jun n-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability. Mol Cell Biol 29(24):6380-6390
    • (2009) Mol Cell Biol , vol.29 , Issue.24 , pp. 6380-6390
    • Densham, R.M.1    O'Neill, E.2    Munro, J.3    Konig, I.4    Anderson, K.5    Kolch, W.6    Olson, M.F.7
  • 14
    • 0037192852 scopus 로고    scopus 로고
    • Akt/pkb phosphorylation of p21cip/waf1 enhances protein stability of p21cip/waf1 and promotes cell survival
    • Li Y, Dowbenko D, Lasky LA (2002) Akt/pkb phosphorylation of p21cip/waf1 enhances protein stability of p21cip/waf1 and promotes cell survival. J Biol Chem 277(13):11352-11361
    • (2002) J Biol Chem , vol.277 , Issue.13 , pp. 11352-11361
    • Li, Y.1    Dowbenko, D.2    Lasky, L.A.3
  • 15
    • 0037119470 scopus 로고    scopus 로고
    • The stress-activated protein kinases p38 alpha and jnk1 stabilize p21(cip1) by phosphorylation
    • Kim GY, Mercer SE, Ewton DZ, Yan Z, Jin K, Friedman E (2002) The stress-activated protein kinases p38 alpha and jnk1 stabilize p21(cip1) by phosphorylation. J Biol Chem 277(33): 29792-29802
    • (2002) J Biol Chem , vol.277 , Issue.33 , pp. 29792-29802
    • Kim, G.Y.1    Mercer, S.E.2    Ewton, D.Z.3    Yan, Z.4    Jin, K.5    Friedman, E.6
  • 16
    • 67649205804 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21cip1
    • Hwang CY, Lee C, Kwon KS (2009) Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21cip1. Mol Cell Biol 29(12): 3379-3389
    • (2009) Mol Cell Biol , vol.29 , Issue.12 , pp. 3379-3389
    • Hwang, C.Y.1    Lee, C.2    Kwon, K.S.3
  • 17
    • 0037155824 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 couples akt-dependent signaling to the regulation of p21cip1 degradation
    • Rossig L, Badorff C, Holzmann Y, Zeiher AM, Dimmeler S (2002) Glycogen synthase kinase-3 couples akt-dependent signaling to the regulation of p21cip1 degradation. J Biol Chem 277(12):9684-9689
    • (2002) J Biol Chem , vol.277 , Issue.12 , pp. 9684-9689
    • Rossig, L.1    Badorff, C.2    Holzmann, Y.3    Zeiher, A.M.4    Dimmeler, S.5
  • 18
    • 2442651763 scopus 로고    scopus 로고
    • Ucn-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogenactivated protein/extracellular signal-regulated kinase kinase/ extracellular signal-regulated kinase pathway
    • Facchinetti MM, De Siervi A, Toskos D, Senderowicz AM (2004) Ucn-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogenactivated protein/extracellular signal-regulated kinase kinase/ extracellular signal-regulated kinase pathway. Cancer Res 64(10):3629-3637
    • (2004) Cancer Res , vol.64 , Issue.10 , pp. 3629-3637
    • Facchinetti, M.M.1    De Siervi, A.2    Toskos, D.3    Senderowicz, A.M.4
  • 19
    • 10344256186 scopus 로고    scopus 로고
    • Prostaglandin a2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein hur
    • Yang X, Wang W, Fan J, Lal A, Yang D, Cheng H, Gorospe M (2004) Prostaglandin a2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein hur. J Biol Chem 279(47):49298-49306
    • (2004) J Biol Chem , vol.279 , Issue.47 , pp. 49298-49306
    • Yang, X.1    Wang, W.2    Fan, J.3    Lal, A.4    Yang, D.5    Cheng, H.6    Gorospe, M.7
  • 22
    • 0024356008 scopus 로고
    • Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay
    • Plumb JA, Milroy R, Kaye SB (1989) Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay. Cancer Res 49(16):4435-4440
    • (1989) Cancer Res , vol.49 , Issue.16 , pp. 4435-4440
    • Plumb, J.A.1    Milroy, R.2    Kaye, S.B.3
  • 23
    • 0033104495 scopus 로고    scopus 로고
    • Apoptosis inhibitory activity of cytoplasmic p21(cip1/waf1) in monocytic differentiation
    • Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K, Mizutani S (1999) Apoptosis inhibitory activity of cytoplasmic p21(cip1/waf1) in monocytic differentiation. EMBO J 18(5):1223-1234
    • (1999) EMBO J , vol.18 , Issue.5 , pp. 1223-1234
    • Asada, M.1    Yamada, T.2    Ichijo, H.3    Delia, D.4    Miyazono, K.5    Fukumuro, K.6    Mizutani, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.