Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity

Toxicology

Volumn 315, Issue 1, 2014, Pages 8-16

  Sakai, Rina ^a,b   Kondo, Chiaki ^a   Oka, Hiroyuki ^a   Miyajima, Hirofumi ^a   Kubo, Kihei ^b   Uehara, Takeki ^a  

^a SHIONOGI AND CO LTD   (Japan)

^b Osaka Prefecture University   (Japan)

Author keywords

Clastogenicity; Cyclin dependent kinase inhibitor 1A (CDKN1A) p21; DNA damage; TK6 lymphoblastoid cell line; Toxicogenomics

Indexed keywords

ATAXIN 1; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; ETOPOSIDE; HYDROXYUREA; KRUPPEL LIKE FACTOR 6; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; MITOMYCIN; PROTEIN P21; TRANSCRIPTION FACTOR 7 LIKE 1;

ARTICLE; CHROMOSOME ABERRATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSS LINKING; DNA DAMAGE; DNA DAMAGE INDUCED CLASTOGENICITY; DNA REPLICATION; DNA SYNTHESIS; FOLLOW UP; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; MICRONUCLEUS; MUTAGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

EID: 84889572243     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.10.009     Document Type: Article

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