Ubiquitination of p21Cip1/WAF1 by SCFSkp2: Substrate requirement and ubiquitination site selection

Biochemistry

Volumn 44, Issue 44, 2005, Pages 14553-14564

  Wang, Wei ^a   Nacusi, Lucas ^b   Sheaff, Robert J ^b   Liu, Xuedong ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; DEGRADATION; DNA; ENZYME INHIBITION; ENZYMES;

LYSINE RESIDUES; MULTIPLE PROTEOLYTIC PATHWAYS; MUTATIONS; UBIQUITINATION;

PROTEINS;

CELL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; LYSINE; POTEIN SCF SKP2; PROTEIN CU11; PROTEIN RBX1; PROTEIN SKP1; S PHASE KINASE ASSOCIATED PROTEIN 2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN E; S PHASE KINASE ASSOCIATED PROTEIN; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; UBIQUITINATION; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HUMANS; LYSINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; S-PHASE KINASE-ASSOCIATED PROTEINS; SUBSTRATE SPECIFICITY; UBIQUITIN;

EID: 27644451320     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051071j     Document Type: Article

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