Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after γ-irradiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 3, 1999, Pages 1002-1007

  Brugarolas, James ^a,d   Moberg, Ken ^a   Boyd, Scott D ^a   Taya, Yoichi ^c   Jacks, Tyler ^a,b   Lees, Jacqueline A ^a  

^a Center for Cancer Research   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; DNA; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; DNA DAMAGE; EMBRYO; ENZYME ASSAY; FIBROBLAST CULTURE; GAMMA IRRADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINOBLASTOMA; TUMOR SUPPRESSOR GENE;

ANIMALS; CDC2-CDC28 KINASES; CELL CYCLE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA DAMAGE; EMBRYO; ENZYME INHIBITORS; FIBROBLASTS; G1 PHASE; GAMMA RAYS; MICE; PEPTIDE MAPPING; PHOSPHOPEPTIDES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RETINOBLASTOMA PROTEIN;

ANIMALIA; MAMMALIA;

EID: 0033514441     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.3.1002     Document Type: Article

References (43)

1. Weinberg, R. A. (1992) Cancer Surv. 12, 43-57.
2. Nevins, J., Leone, G., Degregori, J. & Jakoi, L. (1997) J. Cell Physiol. 173, 233-236.
3. Weintraub, S. J., Prater, C. A. & Dean, D. C. (1992) Nature (London) 358, 259-261.
4. Bremner, R., Cohen, B. L., Sopta, M., Hamel, P. A., Ingles, C.J., Gallie, B. L. & Phillips, R. A. (1995) Mol. Cell. Biol. 15, 3256-3265.
5. Weintraub, S. J., Chow, K. N., Luo, R. X., Zhang, S. H., He, S. & Dean, D. C. (1995) Nature (London) 375, 812-815.
6. Dyson, N. & Harlow, E. (1992) Cancer Surv. 12, 161-195.
7. Lees, J. A., Buchkovich, K. J., Marshak, D. R., Anderson, C. W. & Harlow, E. (1991) EMBO J. 10, 4279-4289.
8. Hinds, P. W., Mittnacht, S., Dyulic, V., Arnold, A., Reed, S. I. & Weinberg, R. A. (1992) Cell 70, 993-1006.
9. Ewen, M. E., Sluss, H. K., Sherr, C. J., Matsushime, H., Kato, J. & Livingston, D. M. (1993) Cell 73, 487-497.
10. Matsushime, H., Quelle, D. E., Shurtleff, S. A., Shibuya, M., Sherr, C. J. & Kato, J. Y. (1994) Mol. Cell. Biol. 14, 2066-2076.
11. Meyerson, M. & Harlow, E. (1994) Mol. Cell. Biol. 14, 2077-2086.
12. Connell-Crowley, L., Harper, J. W. & Goodrich, D. W. (1997) Mol. Biol. Cell 8, 287-301.
13. Zarkowska, T. & Mittnacht, S. (1997) J. Biol. Chem. 272, 12738-12746.
14. Lukas, J., Parry, D., Aagaard, L., Mann, D. J., Bartkova, J., Strauss, M., Peters, G. & Bartek, J. (1995) Nature (London) 375, 503-506.
15. Lukas, J. J. B., Rohde, M., Strauss, M. & Bartek, J. (1995) Mol. Cell. Biol. 15, 2600-2611.
16. Ezhevsky, S. A., Nagahara, H., Vocero-Akbani, A. M., Gius, D. R., Wei, M. C. & Dowdy, S. F. (1997) Proc. Natl. Acad. Sci. USA 94, 10699-10704.
17. Lundberg, A. S. & Weinberg, R. A. (1998) Mol. Cell. Biol. 18, 753-761.
18. Ohtsubo, M., Theodoras, A. M., Schumacher, J., Roberts, J. M. & Pagano, M. (1995) Mol. Cell. Biol. 15, 2612-2624.
19. Paulovich, A. G., Toczyski, D. P. & Hartwell, L. H. (1997) Cell 88, 315-321.
20. Kastan, M., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B. & Fornace, A. J., Jr. (1992) Cell 71, 587-597.
21. Lane, D. P. (1992) Nature (London) 358, 15-16.
22. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. & Vogelstein, B. (1993) Cell 75, 817-825.
23. Gu, Y., Turck, W. & Morgan, D. O. (1993) Nature (London) 366, 707-710.
24. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K. & Elledge, S. J. (1993) Cell 75, 805-816.
25. Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R. & Beach, D. (1993) Science 366, 701-704.
26. Brugarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T. & Hannon, G. J. (1995) Nature (London) 377,552-557.
27. Deng, C., Zhang, P., Harper, J. W., Elledge, S. & Leder, P. (1995) Cell 82, 675-684.
28. Waldman, T., Kinzler, K. W. & Vogelstein, B. (1995) Cancer Res. 55, 5187-5190.
29. Dulic, V., Kaufmann, W. K., Wilson, S. J., Tlsty. T. D., Lees, E., Harper, J. W., Elledge, S. J. & Reed, S. I. (1994) Cell 76, 1013-1023.
30. Slebos, R. J. C., Lee, M. H., Plunkett, B. S., Kessis, T. D., Williams, B. O., Jacks, T., Hedrick, T., Kastan, M. B. & Cho, R. C. (1994) Proc. Natl. Acad. Sci. USA 91, 5320-5324.
31. Demers, G. W., Foster, S. A., Halbert, C. L. & Galloway, D. A. (1997) Genes Dev. 11, 2090-2100.
32. Funk, J. O., Waga, S., Harry, J. B., Espling, E., Stillman, B. & Galloway, D. A. (1997) Genes Dev. 11, 2090-2100.
33. Jones, D. L., Alani, R. M. & Munger, K. (1997) Genes Dev. 11, 2101-2111.
34. Brugarolas, J., Bronson, R. T. & Jacks, T. (1998) J. Cell Biol. 141, 503-514.
35. Kitagawa, M., Higashi, H., Jung, H. K., Suzuki-Takahashi, I., Ikeda, M., Tamai, K., Kato, J., Segawa, K., Yoshida, E., Nishimura, S. & Taya, Y. (1996) EMBO J. 15, 7060-7069.
36. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. & Craig, R. W. (1991) Cancer Res. 51, 6304-6311.
37. Terada, Y., Tatsuka, M., Jinno, S. & Okayama, H. (1995) Nature (London) 376, 358-362.
38. Poon, R., Jiang, W., Toyoshima, H. & Hunter, T. (1996) J. Biol. Chem. 271, 13283-13291.
39. Harrington, E. A., Bruce, J. L., Harlow, E. & Dyson, N. (1998) Proc. Natl. Acad. Sci. USA 95, 11945-11950.
40. Serrano, M., Gomez-Lahoz, E., DePhino, R. A. & Bar-Sagi, D. (1995) Science 267, 249-252.
41. Petrocelli, T., Poon, R., Drucker, D. J., Slingerland, J. M. & Rosen, C. F. (1996) Oncogene 12, 1387-1396.
42. Lowe, S. W., Ruley, E., Jacks, T. & Housman, D. E. (1993) Cell 74, 957-967.
43. Almasan, Y., Yin, Y., Kelly, R. E., Lee, E. Y., Bradley, A., Li, W., Bertino, J. R. & Wahl, G. M. (1995) Proc. Natl. Acad. Sci. USA 92, 5436-5440.