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Volumn 15, Issue 9, 2004, Pages 3965-3976

p21-mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; CYCLINE; DNA; PROTEIN KINASE; PROTEIN P21; RETINOBLASTOMA PROTEIN;

EID: 4344574113     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E03-12-0871     Document Type: Article
Times cited : (162)

References (48)
  • 1
    • 0029147732 scopus 로고
    • Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase
    • Aprelikova, O., Xiong, Y., and Liu, E.T. (1995). Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J. Biol. Chem. 270, 18195-18197.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18195-18197
    • Aprelikova, O.1    Xiong, Y.2    Liu, E.T.3
  • 2
    • 0032965769 scopus 로고    scopus 로고
    • Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition
    • Barboule, N., Lafon, C., Chadebech, P., Vidal, S., and Valette, A. (1999). Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition. FEBS Lett. 444, 32-37.
    • (1999) FEBS Lett. , vol.444 , pp. 32-37
    • Barboule, N.1    Lafon, C.2    Chadebech, P.3    Vidal, S.4    Valette, A.5
  • 3
    • 0042025008 scopus 로고    scopus 로고
    • Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts
    • Baus, F., Gire, V., Fisher, D., Piette, J., and Dulic, V. (2003). Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts. EMBO J. 22, 3992-4002.
    • (2003) EMBO J. , vol.22 , pp. 3992-4002
    • Baus, F.1    Gire, V.2    Fisher, D.3    Piette, J.4    Dulic, V.5
  • 4
    • 0030308967 scopus 로고    scopus 로고
    • Regulation of Cdc2 activity by phosphorylation at T14/Y15
    • Berry, L.D., and Gould, K.L. (1996). Regulation of Cdc2 activity by phosphorylation at T14/Y15. Prog. Cell Cycle Res. 2, 99-105.
    • (1996) Prog. Cell Cycle Res. , vol.2 , pp. 99-105
    • Berry, L.D.1    Gould, K.L.2
  • 5
    • 0029981099 scopus 로고    scopus 로고
    • Sequential dephosphorylation of p34(cdc2) on Thr-14 and Tyr-15 at the prophase/metaphase transition
    • Borgne, A., and Meijer, L. (1996). Sequential dephosphorylation of p34(cdc2) on Thr-14 and Tyr-15 at the prophase/metaphase transition. J. Biol. Chem. 271, 27847-27854.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27847-27854
    • Borgne, A.1    Meijer, L.2
  • 7
    • 0032997651 scopus 로고    scopus 로고
    • Use of CDC2 from etoposide-treated cells as substrate to assay CDC25 phosphatase activity
    • Cans, C., Sert, V., De Rycke, J., Baldin, V., and Ducommun, B. (1999). Use of CDC2 from etoposide-treated cells as substrate to assay CDC25 phosphatase activity. Anticancer Res. 19, 1241-1244.
    • (1999) Anticancer Res. , vol.19 , pp. 1241-1244
    • Cans, C.1    Sert, V.2    De Rycke, J.3    Baldin, V.4    Ducommun, B.5
  • 8
    • 0033533612 scopus 로고    scopus 로고
    • 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
    • Chan, T.A., Hermeking, H., Lengauer, C., Kinzler, K.W., and Vogelstein, B. (1999). 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 401, 616-620.
    • (1999) Nature , vol.401 , pp. 616-620
    • Chan, T.A.1    Hermeking, H.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 11
    • 0034713226 scopus 로고    scopus 로고
    • Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events
    • De Souza, C.P., Ellem, K.A., and Gabrielli, B.G. (2000). Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events. Exp. Cell Res. 257, 11-21.
    • (2000) Exp. Cell Res. , vol.257 , pp. 11-21
    • De Souza, C.P.1    Ellem, K.A.2    Gabrielli, B.G.3
  • 15
    • 0031594705 scopus 로고    scopus 로고
    • Nuclear accumulation of p21Cip1 at the onset of mitosis: A role at the G2/M-phase transition
    • Dulic, V., Stein, G.H., Far, D.F., and Reed, S.I. (1998). Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition. Mol. Cell. Biol. 18, 546-557.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 546-557
    • Dulic, V.1    Stein, G.H.2    Far, D.F.3    Reed, S.I.4
  • 16
  • 17
    • 0033166064 scopus 로고    scopus 로고
    • Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
    • Hagting, A., Jackman, M., Simpson, K., and Pines, J. (1999). Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal. Curr. Biol. 9, 680-689.
    • (1999) Curr. Biol. , vol.9 , pp. 680-689
    • Hagting, A.1    Jackman, M.2    Simpson, K.3    Pines, J.4
  • 18
    • 0032528290 scopus 로고    scopus 로고
    • MPF localization is controlled by nuclear export
    • Hagting, A., Karlsson, C., Clute, P., Jackman, M., and Pines, J. (1998). MPF localization is controlled by nuclear export. EMBO J. 17, 4127-4138.
    • (1998) EMBO J. , vol.17 , pp. 4127-4138
    • Hagting, A.1    Karlsson, C.2    Clute, P.3    Jackman, M.4    Pines, J.5
  • 19
    • 0029058587 scopus 로고
    • Inhibition of cyclin-dependent kinases by p21
    • Harper, J.W., et al. (1995). Inhibition of cyclin-dependent kinases by p21. Mol. Biol. Cell 6, 387-400.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 387-400
    • Harper, J.W.1
  • 20
    • 0027244234 scopus 로고
    • Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase
    • Heald, R., McLoughlin, M., and McKeon, F. (1993). Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell 74, 463-474.
    • (1993) Cell , vol.74 , pp. 463-474
    • Heald, R.1    McLoughlin, M.2    McKeon, F.3
  • 22
    • 0141429171 scopus 로고    scopus 로고
    • Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
    • Hirota, T., Kunitoku, N., Sasayama, T., Marumoto, T., Zhang, D., Nitta, M., Hatakeyama, K., and Saya, H. (2003). Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 114, 585-598.
    • (2003) Cell , vol.114 , pp. 585-598
    • Hirota, T.1    Kunitoku, N.2    Sasayama, T.3    Marumoto, T.4    Zhang, D.5    Nitta, M.6    Hatakeyama, K.7    Saya, H.8
  • 23
    • 0037322744 scopus 로고    scopus 로고
    • Active cyclin B1-Cdk1 first appears on centrosomes in prophase
    • Jackman, M., Lindon, C., Nigg, E.A., and Pines, J. (2003). Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat. Cell Biol. 5, 143-148.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 143-148
    • Jackman, M.1    Lindon, C.2    Nigg, E.A.3    Pines, J.4
  • 24
    • 0031749011 scopus 로고    scopus 로고
    • Nuclear localization of cyclin B1 controls mitotic entry after DNA damage
    • Jin, P., Hardy, S., and Morgan, D.O. (1998). Nuclear localization of cyclin B1 controls mitotic entry after DNA damage. J. Cell Biol. 141, 875-885.
    • (1998) J. Cell Biol. , vol.141 , pp. 875-885
    • Jin, P.1    Hardy, S.2    Morgan, D.O.3
  • 25
    • 0031686960 scopus 로고    scopus 로고
    • Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities
    • Kaldis, P., Russo, A.A., Chou, H.S., Pavletich, N.P., and Solomon, M.J. (1998). Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities. Mol. Biol. Cell 9, 2545-2560.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 2545-2560
    • Kaldis, P.1    Russo, A.A.2    Chou, H.S.3    Pavletich, N.P.4    Solomon, M.J.5
  • 26
    • 0028979436 scopus 로고
    • p21CIP1 is not required for the early G2 checkpoint response to ionizing radiation
    • Levedakou, E.N., Kaufmann, W.K., Alcorta, D.A., Galloway, D.A., and Paules, R.S. (1995). p21CIP1 is not required for the early G2 checkpoint response to ionizing radiation. Cancer Res. 55, 2500-2502.
    • (1995) Cancer Res. , vol.55 , pp. 2500-2502
    • Levedakou, E.N.1    Kaufmann, W.K.2    Alcorta, D.A.3    Galloway, D.A.4    Paules, R.S.5
  • 27
    • 0037195281 scopus 로고    scopus 로고
    • DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
    • Mikhailov, A., Cole, R.W., and Rieder, C.L. (2002). DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint. Curr. Biol. 12, 1797-1806.
    • (2002) Curr. Biol. , vol.12 , pp. 1797-1806
    • Mikhailov, A.1    Cole, R.W.2    Rieder, C.L.3
  • 28
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D.O. (1995). Principles of CDK regulation. Nature 374, 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 29
    • 0035956258 scopus 로고    scopus 로고
    • Biological activities and molecular targets of the human papillomavirus E7 oncoprotein
    • Munger, K., Basile, J.R., Duensing, S., Eichten, A., Gonzalez, S.L., Grace, M., and Zacny, V.L. (2001). Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene 20, 7888-7898.
    • (2001) Oncogene , vol.20 , pp. 7888-7898
    • Munger, K.1    Basile, J.R.2    Duensing, S.3    Eichten, A.4    Gonzalez, S.L.5    Grace, M.6    Zacny, V.L.7
  • 30
    • 0025988705 scopus 로고
    • Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates
    • Norbury, C., Blow, J., and Nurse, P. (1991). Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J. 10, 3321-3329.
    • (1991) EMBO J. , vol.10 , pp. 3321-3329
    • Norbury, C.1    Blow, J.2    Nurse, P.3
  • 31
    • 0032910170 scopus 로고    scopus 로고
    • Regulating the onset of mitosis
    • Ohi, R., and Gould, K.L. (1999). Regulating the onset of mitosis. Curr. Opin. Cell Biol. 11, 267-273.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 267-273
    • Ohi, R.1    Gould, K.L.2
  • 33
    • 0024427288 scopus 로고
    • Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2
    • Pines, J., and Hunter, T. (1989). Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2. Cell 58, 833-846.
    • (1989) Cell , vol.58 , pp. 833-846
    • Pines, J.1    Hunter, T.2
  • 34
    • 0035144407 scopus 로고    scopus 로고
    • Re-staging mitosis: A contemporary view of mitotic progression
    • Pines, J., and Rieder, C.L. (2001). Re-staging mitosis: a contemporary view of mitotic progression. Nat. Cell Biol. 3, E3-E6.
    • (2001) Nat. Cell Biol. , vol.3
    • Pines, J.1    Rieder, C.L.2
  • 35
    • 0642286495 scopus 로고    scopus 로고
    • Cyclin B1 and Cdk 1, nuclear localisation and upstream regulators
    • Porter, L.A., and Donoghue, D.J. (2003). Cyclin B1 and Cdk 1, nuclear localisation and upstream regulators. Prog. Cell Cycle Res. 5, 335-447.
    • (2003) Prog. Cell Cycle Res. , vol.5 , pp. 335-447
    • Porter, L.A.1    Donoghue, D.J.2
  • 36
    • 0037080483 scopus 로고    scopus 로고
    • E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
    • Ren, B., Cam, H., Takahashi, Y., Volkert, T., Terragni, J., Young, R.A., and Dynlacht, B.D. (2002). E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev. 16, 245-256.
    • (2002) Genes Dev. , vol.16 , pp. 245-256
    • Ren, B.1    Cam, H.2    Takahashi, Y.3    Volkert, T.4    Terragni, J.5    Young, R.A.6    Dynlacht, B.D.7
  • 37
    • 0028345406 scopus 로고
    • Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp
    • Roca, J., Ishida, R., Berger, J.M., Andoh, T., and Wang, J.C. (1994). Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc. Natl. Acad. Sci. USA 91, 1781-1785.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1781-1785
    • Roca, J.1    Ishida, R.2    Berger, J.M.3    Andoh, T.4    Wang, J.C.5
  • 38
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou, E.P., Boon, C., Redon, C., and Bonner, W.M. (1999). Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146, 905-916.
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 39
    • 0030611780 scopus 로고    scopus 로고
    • p21CIP1 and Cdc25A: Competition between an inhibitor and an activator of cyclin-dependent kinases
    • Saha, P., Eichbaum, Q., Silberman, E.D., Mayer, B.J., and Dutta, A. (1997). p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases. Mol. Cell. Biol. 17, 4338-4345.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4338-4345
    • Saha, P.1    Eichbaum, Q.2    Silberman, E.D.3    Mayer, B.J.4    Dutta, A.5
  • 40
    • 0034730246 scopus 로고    scopus 로고
    • p21 inhibits thr161 phosphorylation of cdc2 to enforce the G2 DNA damage checkpoint
    • Smits, V.A., Klompmaker, R., Vallenius, T., Rijksen, G., Makela, T.P., and Medema, R.H. (2000). p21 inhibits thr161 phosphorylation of cdc2 to enforce the G2 DNA damage checkpoint [In Process Citation]. J. Biol. Chem. 275, 30638-30643.
    • (2000) J. Biol. Chem. , vol.275 , pp. 30638-30643
    • Smits, V.A.1    Klompmaker, R.2    Vallenius, T.3    Rijksen, G.4    Makela, T.P.5    Medema, R.H.6
  • 41
    • 0035810054 scopus 로고    scopus 로고
    • Regulation of the G2/M transition by p53
    • Taylor, W.R., and Stark, G.R. (2001). Regulation of the G2/M transition by p53. Oncogene 20, 1803-1815.
    • (2001) Oncogene , vol.20 , pp. 1803-1815
    • Taylor, W.R.1    Stark, G.R.2
  • 42
    • 0032525308 scopus 로고    scopus 로고
    • Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint
    • Toyoshima, F., Moriguchi, T., Wada, A., Fukuda, M., and Nishida, E. (1998). Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint. EMBO J. 17, 2728-2735.
    • (1998) EMBO J. , vol.17 , pp. 2728-2735
    • Toyoshima, F.1    Moriguchi, T.2    Wada, A.3    Fukuda, M.4    Nishida, E.5
  • 43
    • 0034788964 scopus 로고    scopus 로고
    • 14-3-3 proteins: Key regulators of cell division, signalling and apoptosis
    • van Hemert, M.J., Steensma, H.Y., and van Heusden, G.P. (2001). 14-3-3 proteins: key regulators of cell division, signalling and apoptosis. Bioessays 23, 936-946.
    • (2001) Bioessays , vol.23 , pp. 936-946
    • Van Hemert, M.J.1    Steensma, H.Y.2    Van Heusden, G.P.3
  • 44
    • 0034813364 scopus 로고    scopus 로고
    • Role of p14(ARF) in replicative and induced senescence of human fibroblasts
    • Wei, W., Hemmer, R.M., and Sedivy, J.M. (2001). Role of p14(ARF) in replicative and induced senescence of human fibroblasts. Mol. Cell. Biol. 21, 6748-6757.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6748-6757
    • Wei, W.1    Hemmer, R.M.2    Sedivy, J.M.3
  • 45
    • 0028047288 scopus 로고
    • Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope
    • Westendorf, J.M., Rao, P.N., and Gerace, L. (1994). Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc. Natl. Acad. Sci. USA 91, 714-718.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 714-718
    • Westendorf, J.M.1    Rao, P.N.2    Gerace, L.3
  • 46
    • 0032514364 scopus 로고    scopus 로고
    • p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells
    • Winters, Z.E., Ongkeko, W.M., Harris, A.L., and Norbury, C.J. (1998). p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells. Oncogene 17, 673-684.
    • (1998) Oncogene , vol.17 , pp. 673-684
    • Winters, Z.E.1    Ongkeko, W.M.2    Harris, A.L.3    Norbury, C.J.4
  • 47
    • 0032528001 scopus 로고    scopus 로고
    • Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1
    • Yang, J., Bardes, E.S., Moore, J.D., Brennan, J., Powers, M.A., and Kornbluth, S. (1998). Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1. Genes Dev. 12, 2131-2143.
    • (1998) Genes Dev. , vol.12 , pp. 2131-2143
    • Yang, J.1    Bardes, E.S.2    Moore, J.D.3    Brennan, J.4    Powers, M.A.5    Kornbluth, S.6
  • 48
    • 0035793643 scopus 로고    scopus 로고
    • Combinatorial control of cyclin B1 nuclear trafficking through phosphorylation at multiple sites
    • Yang, J., Song, H., Walsh, S., Bardes, E.S., and Kornbluth, S. (2001). Combinatorial control of cyclin B1 nuclear trafficking through phosphorylation at multiple sites. J. Biol. Chem. 276, 3604-3609.
    • (2001) J. Biol. Chem. , vol.276 , pp. 3604-3609
    • Yang, J.1    Song, H.2    Walsh, S.3    Bardes, E.S.4    Kornbluth, S.5


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